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Tracking the next pandemic: Avian Flu Talk

Bird flu could hit U.S. - 10/26/2005

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    Posted: February 10 2006 at 10:50pm


10/26/2005

Bird flu could hit U.S. next year

USA Today (excerpt)

DENVER (AP) — As bird flu is spread continent-to-continent by wild birds,
the seasonal migration that is normally one of nature's wonders is
becoming something scary.

Could bird flu reach North America through migrating birds? Biologists in
Alaska and Canada are keeping an eye out and say it's possible by next
year.

Scientists from several agencies have been monitoring large flocks in the
northern part of this continent since last summer, collecting both live
birds and thousands of samples from bird droppings. The results of those
tests are pending, but so far scientists have not found the virus that is
spreading across Asia.

Of course, the bigger fear is that bird flu will mutate into a flu that is both
contagious and deadly to people and which would quickly spread around
the globe through international travel. The current bird flu is not easily
spread to people.

But scientists are studying the virus' transmission among birds as well. In
the United States, a consortium of government agencies is seeking $5
million over the next three years to test birds along their migratory routes
in the Lower 48 states beginning next spring.

"The patterns (of the virus) in Asia right now would not suggest that it
would come over to North America this fall," said Christopher Brand, chief
of field and lab research for the U.S. Geological Survey's National Wildlife
Health Center in Madison, Wis.

Here's why: Bird flu was observed spreading from domestic poultry to
wild birds in Asia last summer in northern breeding grounds in Siberia.
Most of those birds now are migrating south — along their distinctive
routes called flyways — to India and Bangladesh; others follow
southwestern routes to the eastern Mediterranean and even Africa.

So far, bird flu has been detected in both wild and domestic birds as far
east as the Danube Delta in Romania. The virus was reported in poultry in
Turkey, Romania and Russia.

"There has been a shift in the susceptibility of wild fowl to H5N1,"
acknowledged David Nabarro, chief U.N. coordinator for avian and human
influenza.

Brand says that if those birds maintain the virus over the winter, they
would have the opportunity to bring it back to northern nesting grounds
in Siberia next spring and summer.

While most Siberian flocks don't try to cross the Pacific to North America,
some do cross the narrow Bering Strait to Alaska.

If those birds mingle with birds from Alaska, "there is the possibility the
virus could be transmitted to waterfowl or shorebirds that make their way
here next fall," Brand said.

While many severely infected birds usually die within a few days and are
unable to fly very far, other hardier varieties could carry the disease.

Among the Arctic species under suspicion are hardier, long-distance
fliers like eiders, gulls and geese. "It probably will be spread by one that
isn't killed very easily by it," Brand said


http://www.usatoday.com/news/health/2005-10-25-bird-flu-us_x .htm
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Commentary
.
H5 Wild Bird Flu In Canada Causes More Concern

Recombinomics Commentary
November 1, 2005

The H5N1 virus, which scientists say kills 100 per cent of the birds it
infects......

A wildlife surveillance program that began in August tested 4,800 ducks
in six migratory-bird flyways across Canada. Initial results have found an
H5-type virus in 28 ducks in Quebec and another five in Manitoba, said
Mr. Clark. Results from the other provinces have yet to come back but
they, too, are expected to show some H5 infection.


Some form of H5 virus is normally found in about 7.4 per cent of all wild
fowl, said Mr. Clark.

The above comments are additional causes for concern. The
misconception that H5N1 kills 100% of the birds it affects is widely
quoted in the media, but is clearly incorrect. The WHO warning in the fall
of 2004 was due to the fact that H5N1 from a fatal human case in
Vietnam did not cause death in experimental ducks. Instead the ducks
appeared to be healthy and excreted high levels of stable H5N1. This
concern was borne out by surveys of waterfowl in Vietnam which showed
that 70% were H5N1 positive.

The recent mission report from Russia also detailed about two dozen
species that were H5N1 positive when shot down by hunters, indicating
that asymptomatic waterfowl was widespread. Further support came
from the rapid spread of H5N1 to new areas via migratory birds. After
being detected in long range migratory birds in May at Qinghai Lake,
H5N1 was then reported for the first time in Russia, Kazakhstan, and
Mongolia. Now countries in Europe are reporting H5N1 infections for the
first time.

Although some serotype of influenza is found in a significant portion of
wild birds, the H5 serotype is not found in 7.4%. In Canada, there have
been about 120 deposits at GenBank and only two are H5. One (H5N2)
was detected in 1980 and the other (H5N9) was detected in 1966. Thus,
there have been no H5 isolates reported in the past 25 years, although
that is when most of the deposits from Canada were collected.

The above comments also fail to detail how many of the 4800 birds have
been tested or the frequency of H5 in the positive provinces or detail the
number of species.

Publication of this data would allow for a more accurate analysis of the H5
data collected thus far.

http://www.recombinomics.com/News/11010501/H5N1_WBF_Canada_M ore_Concerns.html
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Corn Quote  Post ReplyReply Direct Link To This Post Posted: February 11 2006 at 12:06am

(Quote from article at top above. )

Of course, the bigger fear is that bird flu will mutate into a flu that is both
contagious and deadly to people and which would quickly spread around
the globe through international travel.

From exports, travel, black market and illegal immigrants. By the time the birds srrive next year it will be people giving it to the birds. I think we're missing the point thinking the birds will come with the flu first here in the US. The biggest threat would be people spreading the virus. .

By the way, What type of precautions do the sample takers use to make sure they don't spread BF amongst the birds when they are handling so many species of in a day testing?. ie new gloves each bird, etc. Or do they just protect people?

The testers could contaminate many foul looking for a few.

 

Speculation is the only tool we have with a threat that can circle the globe in 30 days. Test results&news is slow.Factor in human conditions,politics, money&bingo!The truth!Facts come after the fact.
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Influenza Pandemic of 1918

The influenza pandemic of 1918, also known as “Spanish” flu, killed more
rapidly than any other form of influenza known up to that time. This
particular strain of influenza was especially dangerous to young adults.
The National Office of Vital Statistics in the United States recorded the
distribution of deaths during 1917 showing that the highest levels of
morbidity occurred at the extremes of infancy and old age, and was very
low in between these two age groups. By 1918, morbidity changed
dramatically, and was now highest for the very young, and higher yet for
persons between the ages of twenty and forty. The elderly appeared to be
spared, for the most part.

Thus, the Spanish Flu had two outstanding characteristics:

1) it killed millions of people and
2) most of them were in the prime of their life.

This distinctive strain of influenza swept across the face of the earth in
three major waves between 1918 and 1919. Although it is uncertain as to
where the first wave in the spring of 1918 originated, all available
evidence indicates that it appeared in the United States in March of 1918.
It attracted very little attention because pneumonic complications were
few and deaths even fewer; it appeared as no more than just another bout
with the kind of respiratory disease that so often circulates during that
time of the year. Only later, after the second and third killer waves
appeared did statisticians notice that an unusually large proportion of the
flu and pneumonia victims were young adults.

The second wave occurred during March and April and expanded across
North America, temporarily disrupting the operation of some military
camps and a few factories. It was during this wave that the disease spread
throughout most of the rest of the world. According to records, the
disease reached epidemic proportions in Europe in April. It swept across
the continent in the spring and summer, and the number of casualties
was devastating. In Switzerland alone during the month of July, 53,000
people succumbed to the Spanish Flu.

In late August, the severity of the infection changed, suddenly
transforming into the most dangerous strain (or strains) ever recorded. It
occurred in three major parts of the North Atlantic almost simultaneously:
Freetown. Sierra Leone, where local West Africans were brought together
with British, South African, East African, and Australian soldiers and
sailors; Brest, France, which was the chief port for Allied troops; and
Boston, Massachusetts, one of America’s busiest embarkation ports and a
major crossroads for military and civilian personnel of every nation
involved with the Allied war effort. Massive troop movements and the
disruption of significant segments of the population during World War I
played an important role in the transmission of the disease.

The Origins of the 1957 H2N2 Pandemic

In May 1957, an epidemic of a disease presumed to be influenza was
reported in Hong Kong. After several months of investigation, most
epidemiologists agreed that a strain of influenza virus had surfaced in
China early in 1957. Meanwhile, the disease was spreading outward from
Southeast Asia.

The new strain of influenza, initially referred to as “Asian Flu” had rapidly
spread from Hong Kong to Japan, the Philippines, Malaya, and Indonesia
by the end of May 1957. By June, there were numerous reports of
influenza among passengers and crew on board ships that had departed
from East Asian ports. During June, the disease also spread though India
and the Middle East. Port cities were among the first places to be affected.
Given the nature of international trade, the disease rapidly spread
towards England, and reached the United States.

The Asian strain of influenza continued to be the most pronounced type A
variant internationally for more than a decade. It was at this time that
epidemiologists and biostatisticians seriously started to explore methods
of devising an early warning detection system, at least within the context
of determining the severity of an influenza epidemic and its geographical
locale.

The 1976 Swine Flu "Epidemic"

The details surrounding the swine-influenza "outbreak" of 1976 is
notable because the event lead to a major change in public health policy.
While the exact origins and validity of the Swine Flu outbreak are
unknown, many public health and medical researchers
believed that the type of swine influenza that was recovered from human
victims during the January 1976 outbreak at Fort Dix, New Jersey was so
closely related to the influenza strain that caused more than 500,000
deaths in the United States during the 1918-19 pandemic that to ignore
the possibility of a repeat of that epidemic seemed irresponsible.


As the result, a nationwide inoculation program was instituted. However,
the establishment of such a program was not easy to implement. In spite
of identification of swine flu the proposal for a nationwide inoculation
program gained little support at the federal level during April and May of
that year. Although President Gerald Ford espoused the need for such a
program, there was a consensus among many Congressmen that such a
program was not warranted. The vaccine program did not officially begin
until October.

As history would show, the predicted epidemic failed to materialize.
However, millions became vaccinated, some with devastaing health
consequences. Guillian-Barre Syndrom, a decending paralysis, was not
one of the predicted outcomes, yet occurred with a high degree of
frequency at the height of the vaccination program. The vaccine was
produced by Merck, Inc., but the insurance policy agaist such an
eventuality was underwritten by the United States govenment. The public
ended up paying out millions of dollars in health care benefits to affected
individuals.


http://www.medicalecology.org/diseases/influenza/print_influ enza.htm#sect2.1
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Canada plays down bird flu scare

Last Update: Friday, October 21, 2005. 4:00pm
ABC News Online

The federal Government may impose a blanket ban on all live bird
imports after the discovery of Canadian pigeons with bird flu antibodies
in Melbourne.Officials in Toronto say Canada met all international
requirements for the pigeons that were exported to Australia.

Three of the pigeons were found to have antibodies for avian flu but
quarantine officials say there is no health threat to the public or the local
bird population.Another four of the birds had strains of newcastle disease
and the affected birds have been destroyed.

Agriculture Minister Peter McGauran says Canada's testing regime is to
blame.

"I'm reassured that the Australian system works so well but I am
disturbed that the Canadian authorities certified these birds as disease
free," he said.

But the spokesman for Canada's Minister of Agriculture insisted that
Canada had not been negligent. The pigeons had been tested before they
left Canada, but Canadian labs only look for the live virus, which is
dangerous.

When the birds arrived in Australia they were found to have antibodies for
avian flu, but the spokesman said that antibodies were not dangerous.
Jim Clark from Canada's Food Inspection Agency says his organisation
does not have to test for antibodies if Canada has already been declared
free of the disease.

"In Canada's case we are free of the avian influenza virus and have been
since May 2004," Dr Clark said.

The Federal Government today demanded answers from Canadian
officials over the consignment.

Prime Minister John Howard says a temporary ban on all bird imports
from Canada has been imposed.

"Mr McGauran, the Minister for Agriculture, will raise this matter with the
Canadian High Commissioner," he said.

"Now that's just a short-term immediate response measure. I'm not
suggesting that's going to be long-term, it will depend on those
inquiries," he said.

None of the birds actually has the bird flu virus but the
antibodies mean they have been in contact with the virus at some point.


Canada does not export any live birds or poultry to Australia, except for
occasional small shipments of show pigeons.
The rest of the pigeons are being sent back to Canada.


http://www.abc.net.au/news/newsitems/200510/s1487872.htm
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LIVE AVIAN INFLUENZA VIRUS NOT PRESENT IN EXPORTED
CANADIAN PIGEONS

2005-10-25 - Removal of import restrictions

Ottawa, October 21, 2005 - The Canadian Food Inspection Agency (CFIA)
would like to clarify recent reports on the presence of avian influenza
antibodies in three pigeons out of a shipment of 102 pigeons recently
exported from Canada to Australia.

None of the exported pigeons were infected with or carrying live avian
influenza virus. The birds were neither clinically ill nor capable of making
other birds or humans ill. This determination was confirmed by Canadian
and Australian animal health experts. As no threat to human or animal
health is present, Canada believes the interim import restrictions are
unfortunate as Canada followed all Australian certification requirements
for importing live birds.

Canada remains free of highly pathogenic avian influenza, including the
H5N1 strain, which has been the focus of international attention.

Additional blood tests conducted by Australian authorities had confirmed
the presence of generic AI antibodies in the birds. This finding indicates
that the birds were likely exposed to an AI virus at some point in their
life. Because pigeons are commonly raised outdoors, this finding is not
surprising. Exposure to wild birds, which are known carriers of the virus,
would result in the development of antibodies.

Since the announcement by Australia, Canadian officials have had
ongoing bilateral discussions with their Australian counterparts in hopes
of resuming full trade in live birds as soon as possible. Canada and
Australia are committed to working together, and animal disease experts
from both countries will meet over the weekend to discuss what, if any,
actions are required to lift the trade restrictions.

While both countries are sensitive to the international concerns
associated with AI, actions must be based on sound science.


http://www.inspection.gc.ca/english/corpaffr/newcom/2005/200 51021e.shtml
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Summary of Canadian Findings of H5 Virus in Wild,
Migratory Birds

To date, two types of H5 viruses have been identified in the wild bird
survey - H5N3 and H5N1. It is of critical importance to note that in all
cases, these viruses have been clearly characterized by scientists as low
pathogenic, North American strain. This strain is similar to other H5N1
strains identified in North America in the past.

It is not the highly pathogenic H5N1 Asian subtype, which has been
associated with significant disease in wild and domestic birds that has
infected and killed people.

In fact, the North American strain is very different to the Asian strain and
scientists have characterized approximately 15% structural differences
between the two strains. In genetic terms, this percentage difference is
considered to be very substantial.

These laboratory results are confirmed by the absence of any increased
mortality observed in Canadian birds. All North American samples
originated from healthy birds. This can also be attributed to the low
pathogenic nature of the North American strain, as opposed to the highly
pathogenic Asian strain. (excerpt)


http://www.inspection.gc.ca/english/anima/heasan/disemala/av flu/2005wildsauv/virtype.shtml
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