Click to Translate to English Click to Translate to French  Click to Translate to Spanish  Click to Translate to German  Click to Translate to Italian  Click to Translate to Japanese  Click to Translate to Chinese Simplified  Click to Translate to Korean  Click to Translate to Arabic  Click to Translate to Russian  Click to Translate to Portuguese


Forum Home Forum Home > General Discussion > Latest News
  New Posts New Posts RSS Feed - Ebola Again
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Online Discussion: Tracking new emerging diseases and the next pandemic

Ebola Again

 Post Reply Post Reply Page  <1 34567 8>
Author
Message
MikeL View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 26 2018 at 11:03am
Lysosomal is a keyword for Niemann-Pick.

Polio-Influenza Vaccines / Lysosomal
http://www.ncbi.nlm.nih.gov/pubmed/28383105

VSV-EBOV was the vaccine used at Mbandaka (843 vacinees), recalling that anti-ebola brincidofovir is an ether lipid analogue of cidofovir. Indeed, in Nieman-Pick disease patients have either a zero or low esterification profile, and in alcoholism, ester bonds are changed to ether bonds in cell walls.

At a certain point, the mechanisms involved become less clear, and names of compounds will change to number names, as in this report from Harvard:

(Ap 2016) VSV / Lysosomal / ZCL278
http://www.ncbi.nlm.nih.gov/pubmed/26912630
'....VSV....lysosomal....'
Back to Top
Technophobe View Drop Down
Senior Moderator
Senior Moderator
Avatar

Joined: January 16 2014
Location: Scotland
Status: Offline
Points: 50675
Post Options Post Options   Thanks (0) Thanks(0)   Quote Technophobe Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 12:59am
["Contained" is old news but there have been no new cases sonce the 6th of June.]

Ebola Outbreak in Democratic Republic Congo is ‘largely contained’: WHO

26 June 2018

Almost two months after the start of the latest Ebola outbreak in the Democratic Republic of Congo (DRC), United Nations health experts announced on Tuesday that the deadly disease has “largely been contained”. 

A total of 55 cases of Ebola have been recorded during the current outbreak of the often-deadly viral infection and 28 people have died, according to the World Health Organization (WHO).

Ebola is endemic in DRC and has been identified there nine times, since 1976. Before the current outbreak in Equateur Province, the most recent episode of the disease was in 2017, in northern Likati province. Four people died and four survived, according to WHO.

Spokesperson Tarik Jasarevic said that the development was an “important step” but “it is not the end”.

Experience has shown us that it only takes one case to set off a fast-moving outbreak - Tarik Jasarevic (WHO)

“We are cautiously confident regarding the situation and know that a continued aggressive response is required,” he said, adding that “experience has shown us that it only takes one case to set off a fast-moving outbreak.”

Ahead of the WHO announcement, there were fears that the disease might continue its spread from rural north-western DRC, along the key Congo River transport route, to the capital Kinshasa, which is home to 10 million people; and also spread to neighbouring countries.

Those concerns were based on the grim toll and progress of the Ebola epidemic in West Africa between 2013 and 2016, which killed more than 11,000 people in Guinea, Liberia and Sierra Leone.

To counter the threat from the current outbreak – and making use of a new vaccine - the UN agency and Doctors Without Frontiers (MSF) quickly coordinated over an inoculation programme that began in the DRC city of Mbandaka, where around one million people live.

This was followed by another round of preventive vaccination in and around the town of Bikoro to the south, where the initial Ebola victims were identified.

According to WHO, the last confirmed case of Ebola in DRC was on 6 June.

Since then, all probable and suspect cases have been declared negative.

A key tactic used to counter the spread of the haemorrhagic disease has been contact-tracing.

During this current episode, WHO and MSF have traced contacts of those who are suspected of having the disease, administering more than 3,200 vaccinations.

The last 161 people to have come into contact with suspected Ebola virus carriers will finish their mandatory follow-up period on 27 June, at which point they will be declared virus-free, WHO says. 

Meanwhile, on the ground in DRC, health teams are following as many as 20 suspect cases a day, said Mr Jasarevic: “We need to keep the work going in DRC to make sure that all suspect cases are being looked for and make sure that there are no new cases.”

https://news.un.org/en/story/2018/06/1013122

Absence of proof is not proof of absence.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 7:06am
Filoviruses were discovered in 1967, and yet no proof is extant that bats are infected with the virus. If such a report exists, we'd like to see it displayed on this thread because Africans believing that bats have something to do with the epidemic are as yet a fairy tale. What is the precise reservoir and vector? Nature is not opposed to invention, invention being part of nature itself. Nature is opposed to myth.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 9:01am
Because Mononegavirales sequences have been found in the genome of the soybean cyst nematode (Heterodera), the trajectory links to Australia and by default, a possible explanation for the origins of the Reston ebola virus (Phillipines):

Progenitor of the Soybean, Australia
'....Table 2. Soybean Pathogens....Glycine microphylla: Soybean Cyst Nematode....'

Because VSV-EBOV vaccine is Diptera-based, the investigative trajectory includes bat-flies as ectoparasites of fruit bats.

'Family Hippoboscidae....Wings either normally developed with 6 or 7 longitudinal veins and alula, or reduced and nonfunctional in Hippoboscinae; wings and halter absent in Melophagus.... Obligate blood-sucking ectoparasites of birds and mammals. Reproduction by adenotropic viviparity. The mature larvae (third instar) are usually deposited away from the host and very soon transform into puparia; though in Melophagus they are laid and pupate in the host's hair.
....
Hippoboscinae, Tribe Ornithomyini.

Ornithoica Rondani, 1878 Ornithoeca emend. O. bistativa Maa, 1966. Pacif. Insects Monogr. 10: 52 (Ornithoica) Type Locality: Borneo Tenom. Sabah -- Distr. Asia: Iran; Oriental Region

O. podicipis von Roeder, 1892: Mitt. naturh. Mus. Hamb. 10(2), Dipteren: 4 (Ornithoica). Type Locality: Sansibar -- Distr. North Africa: Egypt, East Africa.

O. stipituri (Schiner, 1868): Reise Novara, Zool. 2(1)B, 374. Type Locality: Sudney -- Distr.: Asia, Japan, Indoustralia Region.

O. unicolor Speiser, 1900: Annali Mus. cov. Stor. nat Giacomo Doria (2) (20) 40: 556 (Ornithoica) Type Locality: "Sumatra am Singalang-Berge" -- Distr. USSR: KZ, FE; Asia: Japan; Oriental Region.'
(Catalogue of Palearctic Diptera, V. 11 Scathophagidae -- Hypodermatidae, pp. 215 -17)  
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 9:12am
Note ebola virus antibodies discovered in orangutans on Sumatra and Borneo.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 9:28am
The 1980 Kenya case of Marburg was a Frenchman who trekked to Mt. Elgon, but also fed birds that came into his house. He was an electrician for the irrigation pumps at the Nzoia sugar factory.

Nzoia Ebola and Marburg Antibodies

Back to Top
Technophobe View Drop Down
Senior Moderator
Senior Moderator
Avatar

Joined: January 16 2014
Location: Scotland
Status: Offline
Points: 50675
Post Options Post Options   Thanks (0) Thanks(0)   Quote Technophobe Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 10:35am
Originally posted by MikeL MikeL wrote:

Note ebola virus antibodies discovered in orangutans on Sumatra and Borneo.
Good!  That could mean a bit of real justice for poachers and illegal loggers.
Absence of proof is not proof of absence.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 11:50am
Linking the Hippoboscidae to orangutans also means Pongids co-existing with hominids in Ethiopia, which has been documented. Following the Marburg virus evidence links to Edward Hooper's mention of chimpanzee skulls being sent to the museum in Turvuren(see The River: A Journey to the Source of HIV and AIDS).

'Subgenus Ardmoeca Maa, 1969. 

A. schoutedeni (Bequaert, 1945) Psyche 52: 93 (Lynchia) Type Locality: "Mongende, Belgian Congo" -- Distr. USSR: Kazhakstan; Oriental Region.'
(Catalogue of Palaearctic Diptera, V. 11, p. 221)

One must dig deeper to find the chimpanzee connection:

J. Bequaert, Notes on Hippoboscidae.19.
psyche.entclub.org/52/52-088.html
'Specimens Examined: Belgian Congo: Holotype, male, Mongende, off cormorant, Halietor africanus (Gmelin) (H. Schouteden, Congo Museum, Turvuren); Kenya Colony: Allotype, female, Naivasha, off Phalacorcorax carbo lucidus (Lichtenstein) (A. Meinertzhagen, Museum of Comparative Zoology, Cambridge).'

The Marburg-infected electrician (1980) worked at Nzoia, so here is the trajectory of the journey to the hospital in Nairobi, which passes through Naivasha:

Trans-Nzoia County

Lake Naivasha

Naivasha

If not mistaken, cormorants on Lake Naivasha would link to the Marburg-infected electrician who fed crows and other birds at his home. Hippoboscidae links to crows and bats:

'Family Nycteribiidae....Blood-sucking ectoparasites of Chiroptera with adenotropic vivparity. Females bear third instar larvae away from the host, in the neighbourhood of the roosting place; larva is pressed to the substrate, pupation follows immediately. Female larviparous, returning to the host. Emerged imago without ptilinum, puparial operculum opened by the action of the first pair of legs. After hardening the insect searches for its host.
(Çatalogue of Palaerctic Diptera, p. 227)


Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 12:13pm
There is a link to Kashmir, West Sumatra, and the Rothschild collection:

'Subfamily Nycteribiinae, Nycteribia Latreille

Subgenus Nycteribia Latreille, 1796

N. allotopa (Speiser, 1901) Arch. Naturgesch. 67(1): 47 (Nycteribia (Lystropodia)) Type Locality: Liang si Paghe (West-Sumatra) -- Distr. Asia: Afghanistan, China; Oriental Region.

N. allotopa mikado Maa, 1967, Pacif. Insects, 9(4):748 (Nycteribia). Type Locality: Syozyodo Cave, Wiigata-ken, Honshu (Japan) -- Distr. Japan (Honshu); Ryukyu Islands

N. dentata Theodor, 1967: Illustr. Cat. Rothschild Coll. Nycteribiidae (Brit. Mus. Nat. Hist., Publ. 655), London 61: (Nycteribia). Type Locality: "Kashmir (Bumbroo Cave, Matan, Palhgam Road") -- Distr. Asia: Afghanistan; India.'
(Catalogue, op cit, pp.227-8)

Both N. allotopa mikado and N. dentata were discovered the year of the Marburg virus outbreak in Germany, though the Germans would find out that the Marburg agent was circulating in Uganda as early as 1961.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 12:49pm
Following the watercourse from Mbandaka (formerly Coquilhatville), the Ruki River flows into the Busira arriving at Bandaka and Boende. Though yet to find it on a map, Mongende is apparently close to Boende.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 1:55pm
We entered 'syozyodo' as a search term at Pubmed. It retrieved a few refs, with Abe,Y as an author both in 1948 and in 2018. Since Abe is a presidential family name, we further pursue this trajectory. A Yahoo search 'syozyodo' retrieves only one reference:

A Synopsis of Diptera pupipara of Japan -- Hawaii Biological
hbs.bishopmuseum.org/pi/pdf/9(4)-727.pdf

(1948) Abe, Y / Syozyodo / Japanese Encephalitis

(Ap 2018) Abe, Y / Sumoylation in Alzheimer's

Ebola Hijacks Cellular Sumoylation System

There are two other links to sumoylation:


'Ardmoeca ardeae (Macquart, 1835) Hist. Nat. Ins. Dipt. 2: 640 (Olfersia) Type Locality: "En Sicilie" (Italy) -- Distr. in Old World, widely spread.'
(Catalogue, op cit, p.221)

This Ardmoeca species links to A. schoutedeni at Mogende, Belgian Congo. Further, it may parasitize herons, so heron hepatitis would link the evolution of the retroviruses because hepatitis B virus, HIV-1 and HIV-2 have a common ancestor (reverse transcriptase). Tracking the anti-ebola ether-lipid analogue, brincidofovir, and recalling that in Niemann-Pick a cholesterol transporter is critical for filovirus infection, we link a heron virus (first discovered in 1956) in a heron rookery in Japan, reported in the year of the Marburg virus outbreak in Germany:

(1967) Nodamura Virus / Diethyl Ether and Chloroform Resistance

Back to Top
carbon20 View Drop Down
Admin Group
Admin Group


Joined: April 08 2006
Location: West Australia
Status: Offline
Points: 24761
Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: June 27 2018 at 3:11pm
the link i posted to "hot zone " the book is all about the 1980 french man and a lot more on Ebola ,Marburg even an airbourne subtype

the "hot zone" refers to an island in africa where the monkeys/ apes who were not wanted by the Scientists the old infirm diseased were dumped ,(this was back in the 60's when animals were captured by the thousands and  used for experiments) created a "Hot Zone "of viruses

well worth a read 
12 Monkeys...............
1995 ‧ Science fiction film/Thriller ‧ 2h 11m a must for AFT
Back to Top
Technophobe View Drop Down
Senior Moderator
Senior Moderator
Avatar

Joined: January 16 2014
Location: Scotland
Status: Offline
Points: 50675
Post Options Post Options   Thanks (0) Thanks(0)   Quote Technophobe Quote  Post ReplyReply Direct Link To This Post Posted: June 28 2018 at 5:31am

We Have Some Great News About The Ebola Outbreak in Congo

Humans are amazing.

MAX BEARAK, THE WASHINGTON POST

Absence of proof is not proof of absence.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 28 2018 at 7:11am
One approach is to have a companion text to the Hot Zone such as Marburg Virus Disease (Martini and Siegert, eds.), because it shows photos such as the "6-shaped" virus morphology, and devotes an entire chapter on Marburg virus hepatitis. As far as is known, Hot Zone does not mention Naivasha, because the Frenchman, being an outdoorsman, was  not documented as having visited the lake there, which is an important clue to possible vectors/reservoirs such as cormorants via Hippoboscidae.

Hot Zone has no index, and most assuredly Hooper's The River should be consulted due to especially the map Preston places at the front of the book.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 28 2018 at 10:32am
Preston (Hot Zone) p. 265, 'Highway' : 'The road to Mount Elgon heads northwest from Nairobi into the Kenya highlands, climbing through green hills that bump against African skies. It goes through small farms and patches of cedar forest, and then it breaks over a crest of land and seems to leap out into space, into a bowl of yellow haze, which is the Rift Valley. The road descends into the Rift, cutting across wrinkled knees of bluffs, until it hits bottom and unravels on a savanna dotted with acacia trees. It skirts the lakes at the bottom of the Rift and passes through groves of fever trees, yellow-green and glowing in the sun. It is detained in cities that dwell by the lakes, and then it turns westward toward a line of blue hills. a straight, narrow, paved two-lane highway, crowded with smoky overlander trucks gasping up the grade, bound for Uganda and Zaire. The road to Mount Elgon is a segment of the AIDS highway, the Kinshasa Highway, the road that cuts Africa in half, along which the AIDS virus traveled during its breakout from somewhere in the African rain forest to every place on earth.'

Consulting The Atlas of Africa, 1973, Editions Jeune Afrique, we find that the agricultural map between Nairobi and Mt. Elgon shows large plantings of pyrethrum just west of Lake Naivasha, and above that Tobacco plantings encircling Nakuru. The pyrethrum was most likely used as insecticide on the tobacco, so at the time of the Marburg outbreak in Germany in 1967, mutations in viruses were occurring in the Lake Naivasha region, prompting the question of migrating cormorants and African Corax between Nzoia area and Naivasha.

Intriguingly, a more rigorous scrutiny of the trajectory did yield the Japanese encephalitis connection to Syozyodo Cave yesterday, whereas today pyrethrum links to encephalitis and by default, Lake Naivasha:

India / Pyrethrum / Japanese Encephalitis
'....fogging with 2% pyrethrum....'
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 29 2018 at 11:04am
Ebola and Marburg virus divergence twixt one another critically depended on their hosts during evolution. Preston's passages on crab-eating monkeys:

'The monkey tree usually hangs out over a river, so that they can relieve themselves without littering the ground....and the troops moves out, leaping through trees, searching for fruit.'
(Preston, Hot Zone p.112 Reston)

We are interested in ebola (not Marburg) antibodies in orangutans on Borneo and Sumatra, a close link to Reston ebola virus. Kaeng Khoi District, Thailand, with Kaeng Khoi being spelled Kaeng Khlo on Macmillan's Book of the World map. It is situated on the Sa Pak River at the edge of a lake.

Kaeng Khoi District
'...."vulture waiting"....Pa Sak River....'

We next verify that Marburg virus has been fou nd in Egyptian fruit bats, Rousettus aegyptiacus:

Genomic Analysis of Filoviruses Associated with Four Viral Hemorrhagic Fever Outbreaks in Uganda and the Democratic Republic of the Congo in 2012, Virology (2013) 442:87-100: '....Indeed, MARV and RAVN viruses have been repeatedly isolated from common African fruit bats, Rousettus aegyptiacus.'


Evolutionary History of Indian Ocean Nycteribiid Bat Flies Mirroring the Ecology of Their Hosts
journals.plos.org/plosone/article?id=10.1371/journal.pone.0075215
'....Species of Eucampsipoda were limiited to Rousettus....E. madagascariensis....Rousettus madagascariensis....E. theodori....Rousettus obliviosus....'

Marburg-infected Rousettus aegyptiacus is also infected with other viruses, and it would be patently absurd to suggest that no blood-sucking bat flies never ingested Marburg virus, the corresponding mechanism would mirror Yersinia pestis plague which is endemic on Madagascar.

May 2017  Egyptian Fruit Bats in South Africa
'....Rousettus aegyptiacus....Wolkberg virus....Kaeng Khoi virus....'


Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 29 2018 at 11:26am
'Nycteribiidae. Subfamily Cyclopdiinae

Genus Eucampsipoda Kolenati, 1857 Kolenati, Wein. Ent. Mschr. 1:62. Type species: Nycteribia hyrtlii Kolenati, 1856: Parasiten der Chiropt., Bruenn: 42 (des. Theodor, 1955: Parasitology 45: 196) (junior synonym of Brachitarsina aegyptia Macquaer, 1851 (Maa, 1965, J. Med. Entomology 1(4):379).

aegyptia (Macquart, 1851): Mem/ Soc. Sci. Agric. Lille, 1850: 282 (Brachitarsina). Type Locality: Egypt -- Distr. Asia: S. Turkey, Lebanon, Israel, Jordan, Iran, North Africa Saudi Arabia, Yemen....hyrtlii....fitzingeri.

Genus Cyclopodia Kolenati, 1863, Kolenati, 1863: Horae Soc. ent. ross., 2:82 Type species: nycteribia sykesii Westwood, 1835, Trqans. Zool. Soc. London, 1:275 (des Musgrave, 1925; Rec. Aust. Mus. 14:299); not Palaearctic.

[greeffi Karsch in Greeff, 1884: Sber. Ges. Befoerd. ges Naturw. Marburg, 1884: 77 (Cyclopodia) Type localities: Sao Tome and Roles. Distr. Afrotropical Region].'
(Catalogue of Palaerctic Diptera V. 11, pp. 233-4)

Sao Tome links ebola vectors and reservoirs in West Africa.
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: June 29 2018 at 11:47am
Eidolon dupreanum
'....Two different host preference patterns occurred in nycteribiids infecting insectivorus bats....'

Pteropus / Eidolon
'....antibodies against Nipah....' 
Back to Top
MikeL View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: June 11 2018
Location: Madison, Wiscon
Status: Offline
Points: 340
Post Options Post Options   Thanks (0) Thanks(0)   Quote MikeL Quote  Post ReplyReply Direct Link To This Post Posted: July 01 2018 at 1:54pm
In developing a Japanese alphabet for use in science and medicine, especially epidemiology, an introductory music video for the alphabet seems worth considering. For example, saxophonist John Coltrane, who died of hepatitis B-caused hepatocellular carcinoma at 41 years of age in 1967, the year of the Marburg virus outbreak in Germany. Ideally, we would ask if Grace Kelly would be interested in being featured in the video. Grace's work appears on the new Manhattan Transfer's album, The Junction, since the passing of founding member, Tim Hauser. Some great musicians are linked to the loss of 461 years of talent due to disease:

The Lost Years: The Impact of Cirrhosis on the History of Jazz (Canadian Journal of Gastroenterology)
europe.pmc.org/articles/PMC2721805
'....Hepatitis B vaccination could improve longevity, but alcoholism and Hepatitis C remain major health issues among jazz musicians.....Hepatocellular carcinoma also claimed major saxophone stylists Stan Getz....and Steve Lacy....It is interesting to speculate where jazz may have gone had John Coltrane and Charlie Parker lived into their 80s rather than succumb to the ravages of liver disease in their 30s. If we assume an average life span 75 years for an adult man, the jazz musicians depicted in Figure 1 have lost a combined 461 years of jazz productivity as a consequence of cirrhosis.'

At the onset of the ebola crisis of 2014, we saw ebola rap emerge from Africa: Ebola in Town "Dont Touch Your Friend."

Stan Getz, who once described himself as "a pale Lester Young," also had this to say:

"There wasn't much choice, I wanted to be a doctor, actually. I think I would have made a good research doctor, with my curiosity."

MikeL recalls attempts to mimick Getz's horn by listening to the Hi-Fi record, which machine was cranking out the music off-key, introducing strange new worlds such as concert C#, F#, B, A flat, etc. Needless to say, the new Japanese alphabet will also be used to score music, at least in MikeL's studio.
Back to Top
Technophobe View Drop Down
Senior Moderator
Senior Moderator
Avatar

Joined: January 16 2014
Location: Scotland
Status: Offline
Points: 50675
Post Options Post Options   Thanks (0) Thanks(0)   Quote Technophobe Quote  Post ReplyReply Direct Link To This Post Posted: July 04 2018 at 3:21pm

Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 14

Report
from World Health Organization
Published on 03 Jul 2018 View Original

1. Situation update

The Ministry of Health and WHO continue to closely monitor the outbreak of Ebola virus disease (EVD) in the Democratic Republic of the Congo. On 27 June 2018, all the people who were exposed to the last confirmed EVD case-patient completed their mandatory 21-day follow up without developing symptoms. This is an important milestone. The last confirmed EVD case in Equateur Province was cured and discharged from the Ebola treatment centre (ETC), following two negative tests on serial laboratory specimens, on 12 June 2018. The response is now focused on intensive surveillance, including active case finding and investigation of suspected cases and alerts.

Since our last report on 26 June 2018 (External Situation report 13), 13 suspected EVD cases were reported in Bikoro (10), Iboko (2) and Wangata (1) health zones. Of the 13 suspected cases, 11 tested negative, while two suspected cases reported on 30 June 2018 are awaiting collection of the second specimens for a repeat test after the first specimens tested negative.

Since the beginning of the outbreak (on 4 April 2018), a total of 55 EVD cases and 29 deaths have been reported, as of 1 July 2018. Of the 55 cases, 38 have been laboratory confirmed, 15 were probable cases (deaths for which it was not possible to collect laboratory specimens for testing) and two were suspected cases. One community death that occurred on 20 May 2018 in Iboko Health Zone was retrospectively identified and reclassified as a probable case, increasing the number of probable cases from 14 to 15. Of the 53 confirmed and probable cases, 29 died, giving a case fatality rate of 54.7%. Twenty-eight (53%) confirmed and probable cases were from Iboko, followed by 21 (40%) from Bikoro and four (8%) from Wangata health zones. Five healthcare workers have been affected, with four confirmed cases and two deaths. A total 24 casepatients with confirmed EVD have been cured since the onset of the outbreak.

Context

On 8 May 2018, the Ministry of Health of the Democratic Republic of the Congo notified WHO of an EVD outbreak in Bikoro Health Zone, Equateur Province. The event was initially reported on 3 May 2018 by the Provincial Health Division of Equateur when a cluster of 21 cases of an undiagnosed illness, involving 17 community deaths, occurred in Ikoko-Impenge health area. A team from the Ministry of Health, supported by WHO and Médecins Sans Frontières (MSF), visited Ikoko-Impenge health area on 5 May 2018 and found five case-patients, two of whom were admitted in Bikoro General Hospital and three were in the health centre in Ikoko-Impenge. Samples were taken from each of the five cases and sent for analysis at the Institute National de Recherche Biomédicale (INRB), Kinshasa on 6 May 2018. Of these, two tested positive for Ebola virus, Zaire ebolavirus species, by reverse transcription polymerase chain reaction (RT-PCR) on 7 May 2018, and the outbreak was officially declared on 8 May 2018. The index case in this outbreak has not yet been identified and epidemiologic investigations are ongoing, including laboratory testing. This is the ninth EVD outbreak in the Democratic Republic of the Congo over the last four decades, with the most recent one occurring in May 2017. Further information on past outbreaks is available at: http://www.who.int/ebola/historical-outbreaksdrc/en/.

Source:   https://reliefweb.int/report/democratic-republic-congo/democratic-republic-congo-ebola-virus-disease-external-situation-12
Absence of proof is not proof of absence.
Back to Top
 Post Reply Post Reply Page  <1 34567 8>
  Share Topic   

Forum Jump Forum Permissions View Drop Down