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Online Discussion: Tracking new emerging diseases and the next pandemic

Ebola drugs show ‘90% survival rate’

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EdwinSm, View Drop Down
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    Posted: August 12 2019 at 9:38pm
The headline is modified by the fact that to get a 90% survival rate the drugs have to be given at an early stage.

Originally posted by BBC BBC wrote:

Four drugs were trialled on patients in the Democratic Republic of Congo, where there is a major outbreak of the virus.

Two of those were considerably more effective in treating the disease, the study found.

The drugs will now be used to treat all Ebola patients in DR Congo, according to health officials.
....
The drugs, named REGN-EB3 and mAb114, work by attacking the Ebola virus with antibodies, neutralising its impact on human cells.

They are the "first drugs that, in a scientifically sound study, have clearly shown a significant diminution in mortality" for Ebola patients, said Dr Anthony Fauci, director of NIAID.

REGN-EB3 and mAb114 were developed using antibodies harvested from survivors of Ebola, which has killed more than 1,800 people in DR Congo in the past year.

Two other treatments, called ZMapp and Remdesivir, have been dropped from trials as they were found to be less effective.
....
Of the patients given the two more effective drugs, 29% on REGN-EB3 and 34% on mAb114 died, NIAID said.

In contrast, 49% on ZMapp and 53% on Remdesivir died in the study, the agency said.

The survival rate among patients with low levels of the virus in their blood was as high as 94% when they were given REGN-EB3, and 89% when on mAb114, the agency said.

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