ECDC-WISO week 3

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   http://ecdc.europa.eu/en/publications/Publications/influenza-surveillance-overview-24-jan-2014.pdf

For week 3/2014: 
• Of the 29 reporting countries, four (Bulgaria, Greece, Portugal and Spain) reported medium-intensity 
influenza and Portugal, Spain and the UK (England) reported geographically widespread activity. 
• Of 1 401 sentinel specimens tested across 27 countries, 447 (32%) were positive for influenza virus. 
• Dominant viruses were reported by Bulgaria, Greece, Portugal, Spain, Sweden, the UK (Scotland) 
(A(H1)pdm09 virus) and Slovenia (A(H3)). 
• Since week 40/2013, France and Spain have reported 33 fatal cases related to influenza virus infection, 19 
(58%) of them being infected with influenza A(H1)pdm09 virus. 
A growing number of countries are reporting an increasing proportion of specimens testing positive for 
influenza virus. Increasing numbers of hospitalised laboratory-confirmed and fatal influenza cases have been 
reported in the last few weeks. 

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Dutch Josh Members Profile Send Private Message Find Members Posts Add to Buddy List Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95867	Post Options Post Reply Quote Dutch Josh Report Post Thanks(0) Quote Reply Topic: ECDC-WISO week 3 Posted: January 24 2014 at 7:15am
	http://ecdc.europa.eu/en/publications/Publications/influenza-surveillance-overview-24-jan-2014.pdf For week 3/2014: • Of the 29 reporting countries, four (Bulgaria, Greece, Portugal and Spain) reported medium-intensity influenza and Portugal, Spain and the UK (England) reported geographically widespread activity. • Of 1 401 sentinel specimens tested across 27 countries, 447 (32%) were positive for influenza virus. • Dominant viruses were reported by Bulgaria, Greece, Portugal, Spain, Sweden, the UK (Scotland) (A(H1)pdm09 virus) and Slovenia (A(H3)). • Since week 40/2013, France and Spain have reported 33 fatal cases related to influenza virus infection, 19 (58%) of them being infected with influenza A(H1)pdm09 virus. A growing number of countries are reporting an increasing proportion of specimens testing positive for influenza virus. Increasing numbers of hospitalised laboratory-confirmed and fatal influenza cases have been reported in the last few weeks.
	We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein

Dutch Josh Members Profile Send Private Message Find Members Posts Add to Buddy List Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95867	Post Options Post Reply Quote Dutch Josh Report Post Thanks(0) Quote Reply Posted: January 24 2014 at 7:23am
	http://pf11.blogspot.nl/2013/09/emergent-h7n9-homology-in-fatal-human.html Again; H1N1 and H7N9 may have "mixed": On 2013-09-25, the Rospotrebnadzor of Moscow, Russia released a set of human pH1N1 sequences without age or gender at GISAID, including 6 Fatal cases. The Neuraminidase segments were not released. One HA segment sampled in late January 2013 from Astrakhan [map], near the Caspian Sea, [EPI471830] strongly suggests Emergent H7N9 involvement. This Astrakhan H7N9-related viral Hemagglutinin displays a standardEmergent H7N9 amino at 179V on a pH1N1 Clade2:188T background. The HA 179V is Novel to pH1N1 after more than 4 years of pH1N1 circulation in humans. HA 89G, found in the H7N9 reservoir, is co-located on this same pH1N1 sequence. Polymorphisms at two antigenic amino positions practically adjacent, HA 129Q and HA 131L, provide grist for the Host-Transition mill. Contemporary sequences from Spain carry homology as well as an unusual change adjacent to these odd aa129 andaa131 positions from the Russian Federation: HA 477M SpainCatalonia5925S_29F_2013_02_05 HA 132S SpainMurcia164_80F_2013_01_30_s Furthermore, SpainMurcia164_80F_2013_01_30_s, an In-Patient case, is on a cross-clade background (HA 188T &189T) and features a polymorphism at aa89 (HA 89N) HA 219T, also seen in the H7N9 reservoir, is demonstrated in Kazan [map], [EPI471827].
	We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein