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Is Q Fever Our Worst Nightmare? |
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Mary008 
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 Topic: Is Q Fever Our Worst Nightmare?Posted: December 14 2009 at 11:40am |
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Image A: A normal chest X-ray. Image B: Q fever pneumonia. C burnetii
wikipedia
There Is A Vaccine For Our Worst Nightmare
And It Isn't Being Widely Given Out....?
...................................................................
No Profit in Curing this?
........................................... Why Are They Not Vaccinating For It? (there is a vaccine ) The incubation period is 9 - 40 days. It can be considered
the most infectious disease in the world,
.......................................................................... as a human being can be infected by
a single bacterium.[2]
.................................................
More..... On Q Fever
................................................ During the course, the disease can progress to an atypical pneumonia,
which can result in a life threatening acute respiratory distress syndrome (ARDS),
whereby such symptoms
usually occur during the first 4 to 5 days of infection.
Sexually transmitted Q fever
....................................................... ................................................................. .............................................................................. Auteur(s) / Author(s)
MILAZZO Adriana (1) ; HALL Robert (1) ; STORM Paul A. (2) ; HARRIS Ray J. (3) ; WINSLOW William (4) ; MARMION Barrie P. (2 4) ; Affiliation(s) du ou des auteurs / Author(s) Affiliation(s) (1) Communicable Disease Control Branch, Department of Human Services, University of Adelaide, Adelaide, South Australia a man with occupationally acquired Q fever to his wife.
Fifteen days after coitus, his wife also developed serologically proven acute Q fever.
C. burnetii DNA sequences were detected by polymerase chain reaction (PCR)
performed on semen samples obtained from the husband at 4 and 15 months after the onset of acute Q fever, but PCR results were variable at 23 months, indicating the presence of few organisms. vol. 33, no3, pp. 399-402 (19 ref.) Journal Title
Clinical infectious diseases ISSN 1058-4838 CODEN CIDIEL 2001
Publisher University of Chicago Press, Chicago, IL, ETATS-UNIS (1992) (Revue) Transmission
Aerosol Cities and towns
Downwind from farms
By roads traveled by animals
Transmission Aerosol Parturient fluids 109 bacteria per gram of placenta Urine, feces, milk Wind-borne Direct contact Fomites Ingestion Arthropods (ticks) Center for Food Security and Public Health Iowa State University - 2004
Center for Food Security and Public Health Iowa State University - 2004
Prevention and Control
Mary008
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Mary008
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Posted: December 14 2009 at 12:17pm |
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C burnetii can cause debilitating diseaseand may result in potentially fatal chronic infections among humans. Although the disease is considered enzootic in the United States, human and animal C burnetii infections are underdiagnosed and underreportedbecause of the protean nature of its clinical signs, the requirement for laboratory tests to establish a diagnosis, and the lack of awareness of this disease in the medical and veterinary communities. Finally, C burnetii is considered a potential agent ofbioterrorism because of its accessibility, low infectious dose, resistance to environmental degradation, and aerosol route of transmission. 52 Because national surveillancefor Q fever is currently lacking in the United States, it would be difficult to detect and respond to a bioterrorism event involving C burnetii. Q fever wasmade nationally notifiable in humans in 1999, and although this represents a critical first step toward improved surveillance, the disease continues to be underreported in the United States. |
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Mary008
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Posted: December 14 2009 at 12:31pm |
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Acute Infection
.............................. Flu-like, self limiting
Atypical pneumonia (30-50%) Non-productive cough, chest pain Acute respiratory distress possible Hepatitis Skin rash (10%) Other signs (< 1%) Myocarditis, pericarditis, meningoencephalitis Death: 1-2% Chronic Disease
.................................... 1-5% of those infected
Prior heart disease, pregnant women, immunocompromised Endocarditis
Other Osteomyelitis Granulomatous hepatitis Cirrhosis 50% relapse rate after antibiotic therapy
......................................................................... .................................................................................... Risk to Pregnant Women ................................................. Most asymptomatic
Transplacental transmission
Reported complications In-utero death Premature birth Low birth weight Placentitis Thrombocytopenia Prognosis
...................... Overall case-fatality rate <1 - 2.4% 50% cases self-limiting Only 2% develop severe disease Active chronic disease Usually fatal if left untreated Fatality for endocarditis: 35-55% 50-60% need valve replacement [PPT] Q Fever Presentation
File Format: Microsoft Powerpoint - View as HTML ... Intradermal inoculation; Possibly sexually transmitted. Epidemiology ... Tested positive for Q fever; Antibiotics for 5 days; Resolved in 2 weeks ... www.cfsph.iastate.edu/DiseaseInfo/ppt/Qfever.ppt |
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Mary008
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Posted: December 14 2009 at 12:34pm |
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.
in week 41-
A/H1N1 is 3,378 cases..... out of 12,943 Influenza Like Cases tested
or...
"... in clinical laboratory specimens (29% of all specimens tested are positive for
influenza A and all of those subtyped are pandemic H1N1 2009 virus."
This means that all Respiratory illnes .... other than Influenza ... is causing 71% of illness. so... what is it called?
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Mary008
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Posted: December 14 2009 at 1:10pm |
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Mary008
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Posted: December 14 2009 at 1:13pm |
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.
Rabies, Q Fever, & Zoonotic Resources
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Mary008
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Posted: December 14 2009 at 1:19pm |
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Will The Dutch Help Bring It Out Into The Open?
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Mary008
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Posted: December 14 2009 at 1:25pm |
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Mary008
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Posted: December 14 2009 at 1:30pm |
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In humans, Q fever is not a clinically distinct illness and may resemble a viral illness
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SheepLady
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Posted: December 14 2009 at 1:36pm |
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Hi, Mary,
Outstanding sources!!!! Occupational hazard is about right.
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SheepLady
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Mary008
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Posted: December 14 2009 at 1:44pm |
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.
 [PDF]
Immunogenicity and reactogenicity of a Q fever chemovaccine in ...File Format: PDF/Adobe Acrobat - View as HTML
by J Kazar - 1982 - Cited by 18 - Related articles South America (14), and in the United States of. America (8). Q fever poses an importam public health problem in Slovakia (/ 7), and long-term studies have ... whqlibdoc.who.int/bulletin/1982/Vol60.../bulletin_1982_60(3)_389-394.pdf  Immuno-histochemistry of C.burnetii in clinical sample |
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Mary008
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Posted: December 14 2009 at 2:01pm |
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Mary008
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Posted: December 14 2009 at 2:05pm |
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Mary008
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Posted: December 14 2009 at 2:44pm |
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.
Why Billions would be spent on Influenza... rather than something as insidious as this
amazing.
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Mary008
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Posted: December 14 2009 at 6:05pm |
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Interesting read...
Acute Q fever has three major manifestations: 1) a self limited febrile illness;
2) pneumonia; and
3) hepatitis. Hard to kill it...
Two studies documented that high winds can result in infection with C. burnetii up to an 11-mile (18.3 km) distance from the point source 13, 39.
Spore-like formation explains why C. burnetii is so successful as a pathogen.
It can survive for 7–10 months on walls
at 15–20°C, for >1 month on meat in cold storage
and for >40 months in skimmed milk at room temperature 8.
And...
exposure to 10% bleach solution for 30 minutes will not kill it :/
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Mary008
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Posted: December 14 2009 at 6:13pm |
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Q fever-related cholecystitis: a missed entity? - Elsevierby S Reina-Serrano - 2005 - Cited by 3 - Related articles - All 4 versions
... burnetii, hepatitis B s antigen, antibodies against hepatitis B c ... tests done 2 weeks later revealed a positive ELISA for C burnetii IgM antibodies. ... linkinghub.elsevier.com/retrieve/pii/S1473309905702747 - Similar Journal of Medical Case Reports | Full text | Coxiella burnetii as ...We report the simultaneous presence of chronic Q-fever hepatitis and autoimmune liver disease. Serology for C. burnetii is highly specific, and we are not ...
www.jmedicalcasereports.com/content/3/1/8870 - Cached Q Fever in Patients with Hepatitis and Pneumonia: Results of ...by LA Sawyer - 1988 - Cited by 19 - Related articles
hepatitis A virus) for antibodies to C burnetii. In addition, se- rum specimens that were submitted for testing with respiratory ... www.jstor.org/stable/30136359 Steroids treatment of Granulomatous hepatitis complicating ...by M CRESPO - 1999 - Cited by 8 - Related articles - All 3 versions
A case of granulomatous hepatitis complicating C. burnetii acute infection is reported, which was refractory to antibiotics but, as in four other cases ... cat.inist.fr/?aModele=afficheN&cpsidt=1718276 - Similar Complement Fixation Test To C Burnetii - a comprehensive view ...Complement Fixation Test To C Burnetii - Health Knowledge Made Personal. ... Diagnosis Hepatitis C is diagnosed by a blood test that can detect antibodies ...
www.wellsphere.com/.../complement-fixation-test-to-c-burnetii - Cached Surveillance Case Definition Q Fever (Coxiella burnetii, Query Fever)File Format: PDF/Adobe Acrobat - Quick View
vascular prosthesis, or chronic hepatitis in the absence of other known etiology AND o Serological evidence of IgG antibody to C. burnetii IFA phase I IgG ... www.state.nj.us/health/cd/documents/casedef/qfever.pdf - Similar Case Definitions for Infectious Conditions Under Public Health ...A, B, C, D ... Corynebacterium diphtheriae (Diphtheria): 1995 | 1990; Coxiella burnetii (Q Fever): 2009 | 2008 ... Hepatitis C virus infection (past or present www.cdc.gov/ncphi/disss/nndss/casedef/case_definitions.htm - Cached - Similar |
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Mary008
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Posted: December 14 2009 at 6:22pm |
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. Surveillance Case Definition
Q Fever
(Coxiella burnetii, Query Fever)
Clinical description Acute infection: A febrile illness (up to 105 F) usually accompanied by rigors, myalgia, malaise, and
retrobulbar headache. Fatigue, night sweats, dyspnea, confusion, nausea, diarrhea, abdominal pain, vomiting, non-productive cough, and chest pain have also been reported. Severe disease can
include acute hepatitis, atypical pneumonia with abnormal radiograph, and meningoencephalitis. Pregnant women are at risk for fetal death and abortion. Clinical laboratory findings may include elevated liver enzyme levels, leukocytosis, and thrombocytopenia. Asymptomatic infections may also occur. Chronic infection: Infection that persists for more than 6 months. Potentially fatal endocarditis may evolve months to years after acute infection, particularly in persons with underlying valvular disease. Infections of aneurysms and vascular prostheses have been reported. Immunocompromised individuals are particularly susceptible. Rare cases of chronic hepatitis without endocarditis, osteomyelitis, osteoarthritis, and pneumonitis have been described. Laboratory criteria for diagnosis Laboratory diagnosis is made by demonstration of the presence of antibodies to C burnetii antigens using indirect immunoflourescent assay (IFA), or enzyme-linked immunosorbent assay (ELISA) methods. Organisms can also be identified in the tissues using immunohistochemical (ICH) staining, DNA detection methods by polymerase chain reaction (PCR), or electron microscopy. Recovery of the organism from blood is diagnostic but poses a hazard to laboratory workers. Microsoft Word - Case_ Definition_Qfever_2008.doc Download (24K) Print (2 pages)Plain HTML patitis+C+burnetii+hep+c&hl=en&gl=us&sig=AHIEtbQ9LIRqOC-HvF5OZ_qkl-Gu2bYn1A
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Mary008
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Posted: December 14 2009 at 11:21pm |
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CDC
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DiagnosisBecause the signs and symptoms of Q fever are not specific to this disease, it is difficult to make an accurate diagnosis without appropriate laboratory testing.
Results from some types of routine laboratory tests in the appropriate clinical and epidemiologic settings may suggest a diagnosis of Q fever.
For example, a platelet count may be suggestive because persons with Q fever may show a transient thrombocytopenia. Confirming a diagnosis of Q fever requires serologic testing to detect the presence ofantibodies to Coxiella burnetii antigens. In most laboratories, theindirect immunofluorescence assay (IFA) is the most dependable and widely used method. Coxiella burnetii may also be identified in infected tissues by using immunohistochemical staining and DNA detection methods.
Coxiella burnetii exists in two antigenic phases called phase I and phase II. This antigenic difference is important in diagnosis. In acute cases of Q fever, the antibody level to phase II is usually higher than that to phase I,
often by several orders of magnitude, and generally is first detected during the second week of illness.
In chronic Q fever, the reverse situation is true.
Antibodies to phase I antigens of C. burnetii generally require longer to appear and indicate continued exposure to the bacteria.
Thus, high levels of antibody to phase I in later specimens in combination with constant or falling levels of phase II antibodies
and other signs of inflammatory disease suggest chronic Q fever.
Antibodies to phase I and II antigens have been known to persist for months or years after initial infection.
Recent studies have shown that greater accuracy in the diagnosis of Q fever can be achieved by looking at specific levels of classes of antibodies other than IgG, namely IgA and IgM. Combined detection of IgM and IgA in addition to IgG improves the specificity of the assays and provides better accuracy in diagnosis. IgM levels are helpful in the determination of a recent infection. In acute Q fever, patients will have IgG antibodies to phase II and IgM antibodies to phases I and II. Increased IgG and IgA antibodies to phase I are often indicative of Q fever endocarditis.
Wow... Imagine trying to test people for that... the time ... the expense
It isn't possible at this time....
It could be anywhere... ( big woop... Biotesting in a few big cities... so there they go ...out to the country, who would know?
Is It Flu? Or Is It Q?
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Doxycycline is the treatment of choice for acute Q fever. Antibiotic treatment is most effective when initiated within the first 3 days of illness. A dose of 100 mg of doxycycline taken orally twice daily for 15-21 days is a frequently prescribed therapy. Quinolone antibiotics have demonstrated good in vitro activity against C. burnetii and may be considered by the physician. Therapy should be started again if the disease relapses. Chronic Q fever endocarditis is much more difficult to treat effectively and often requires the use of multiple drugs. Two different treatment protocols have been evaluated: 1) doxycycline in combination with quinolones for at least 4 years and 2) doxycycline in combination with hydroxychloroquine for 1.5 to 3 years. The second therapy leads to fewer relapses, but requires routine eye exams to detect accumulation of chloroquine. Surgery to remove damaged valves may be required for some cases of C. burnetii endocarditis. |
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Mahshadin
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Posted: December 15 2009 at 11:01am |
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jeese Mary008
You want to start a vaccine campaign for this after what we just went through with influenza vaccine.
My God Mercola and Becks Heads would just explode, we cant have that :-)
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"In a time of universal deceit, telling the truth is a revolutionary act." G Orwell
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Mary008
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Posted: December 15 2009 at 7:34pm |
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Sorry...
Not understanding this... a vaccine campaign? where did you get that?
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