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PANDEMIC ALERT LEVEL
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Tracking the next pandemic: Avian Flu Talk

When Pandemic detected Who change phase

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    Posted: March 07 2006 at 4:33am

According to the PDF version below of the WHO DRAFT PRTOCOL OF THE MEETING GOING ON AT THE MOMENT>  

The draft contains this.

That the decision to change the phase of PANDEMIC alert is expected to trigger a number of cascading actions by countries,possibly including travel resrictions and border closures.

 

PAGE 1 

 First strategy - contain outbreaks ( with quarantines etc). 

Second strategy - Intensify the worlds preparedness to cope with a pandemic. (Information. Stockpile! Antivirals etc.)

 

PAGE 5

Key concepts - assortment and response of any kind after possible early pandemic activity detected.

(Containment achievable if rapid response in place.)

Rapid containment - stop further spread of an emerging pandemic.

(This would slow initial spread to give countries enough time to prepare!)

STOCKPILE - NATIONAL REGIONAL and GLOBAL.

 

Page 10

The first potential signal of early pandemic activity , for example -

Isolation, from a single infected person, of an influenza virus with certain genetic and antigenic features.

Or detection of an expanding cluster of human cases of avian influenza closely related in time and place.

Or detection of a community outbreak of respiratory illness of unknown etiology. 

(Each country is responsible for their own surveillance and detection)!

 

When Who has satisfied itself after much protocol and verification then they will make a decision to change the phase.

 

Page 13

A WHO decision to change the phase of pandemic alert is expected to trigger a number of cascading actions by countries, possibly including travel restrictions and border closures.

END

That is it my friends! No mention of any levels just a straight jump to PANDEMIC!!!!!!!!

Don't panic. Be prepared!

http://www.who.int/csr/disease/avian_influenza/guidelines/Ra pidResponse_27%2001.pdf

Read full PDF version above.

Thanks.

 

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WHO convenes international meeting to discuss influenza pandemic containment strategy


On Monday 6 March 2006, the World Health Organization (WHO) will convene a three-day technical meeting of international public health experts at its Geneva headquarters, to discuss a rapid response strategy in the event of an influenza pandemic emerging.

The meeting will continue development of an operational guide for WHO and other public health authorities to use in an attempt to extinguish a pandemic in its initial stages. Using the draft protocol issued on 27 January 2006 as a departure point, the meeting will define priorities for WHO and its partners as planning for a pandemic containment effort moves forward.

The meeting will focus on three areas: operations (the logistics for mounting such an effort), surveillance and epidemiology, and public health measures (quarantines, anti-viral medicines, social distancing measures, etc.) From 6-8 March, more than 30 experts in a variety of disciplines including epidemiology, virology, public health, and laboratory issues, will discuss how WHO and the global public health community might effectively contain the transmission of a pandemic virus at its source.

A containment protocol will enable a coordinated approach to the rapid detection, assessment, and response to the emergence of a pandemic virus. Halting a pandemic depends on several factors, such as the early identification of the pandemic strain, the ability of the global community to implement containment procedures, and the ability to effectively control the movement of people in and out of the affected area, to prevent further geographical spread of the virus.

Even if the pandemic cannot be stopped, public health interventions might buy time to allow countries to further strengthen their response systems, as well as accelerating the production of pandemic vaccine. While no efforts to extinguish influenza pandemics have ever been attempted, the continued surveillance of the avian influenza H5N1 strain allows the global community a unique opportunity to monitor the evolution of a possible pandemic strain. If there is even a small chance that the enormous health, economic and social damages caused by a pandemic might be averted, then WHO has a responsibility to try.

The opening of the meeting will be open to the public and to journalists from 9:am to 9:45 am. The meeting will begin at 9am on 6 March 2006, in Salle B at WHO headquarters in Geneva, Switzerland.

Related links

- Rapid response and containment draft protocol [pdf 95kb]

For more information contact:

Maria Cheng
Communications Officer
Communicable Diseases, WHO
Telephone: +41 22 791 3982
E-mail: chengm@who.int

Dick Thompson
Communications Officer
Communicable Diseases, WHO
Telephone: +41 22 791 2684
E-mail: thompsond@who.int





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INFORMATION PAPER

 

MCHB-TS-D                                                                                                                       19 November 04

 

 

SUBJECT:  Pneumonia among US military personnel in the US Central Command

Area of Responsibility (USCENTCOM AOR)

 

 

ARMY POSITION:  Pneumonia among US military personnel during Operation Iraqi Freedom (OIF) has been sporadic and lack a common exposure.  Some of these cases resemble acute eosinophilic pneumonia (AEP) and new-onset tobacco smoking is being investigated further as a potential risk factor.  The Army will continue to study this problem and has raised the level of awareness among physicians to enable the earliest possible diagnosis and treatment.

 

KEY POINTS:          

 

a.  From March through August 2003, 19 US military personnel throughout the USCENTCOM AOR developed pneumonia severe enough to warrant medical evacuation and mechanical ventilation; two died.

 

b.  An Army Epidemiological Consultation (EPICON) began in July 2003.  A summary of the investigation was published in September 2003 in the Morbidity and Mortality Weekly Report (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5236a1.htm). 

 

c.  Ten of the 19 severe pneumonia cases in 2003 were diagnosed as acute eosinophilic pneumonia (AEP), a rare but not unknown type of pneumonia.  Since the beginning of OIF 22 US military personnel serving in the USCENTCOM AOR have been diagnosed with AEP; 16 of those were severe cases that required mechanical ventilation.

 

d.  Two-thirds of all AEP patients became ill in Iraq; the remaining seven were in other countries including Kuwait (3), Djibouti (2), Uzbekistan, and Qatar.  There has been no evidence of a common source exposure or person-to-person transmission.

 

e.  The only factor shared by all 22 AEP cases has been cigarette smoking, especially recent onset smoking.  Follow-up investigation has revealed no single infectious cause, nor exposure to chemical or biological weapons (including anthrax), or any specific environmental toxins.

 

 

BACKGROUND:

 

a.   During July-September 2003, USACHPPM deployed epidemiology teams to Landstuhl Regional Medical Center and Iraq to investigate severe pneumonia that appeared to be occurring at an unexpectedly high rate among US troops.  The Walter Reed Army Institute of Research (WRAIR) contributed two senior officers for the Iraq team.  A third, US-based team coordinated the investigation, served as the central data collection point, and collaborated with the Centers for Disease Control and Prevention (CDC) and the WRAIR.   

 

b.  The Office of the Armed Forces Medical Examiner, Armed Forces Institute of Pathology attempted to determine a specific, underlying cause, or causes, of death for the two fatal cases.  Consultation on these cases was obtained from experts within DoD and experts at the Mayo Clinic and the CDC.  No etiologic agent was found for pneumonia in these cases, and there is no evidence that death was directly attributable to the same underlying cause as pneumonia.  Rather, the two Soldiers died of complications of their acute disease.

 

c.  Eosinophils are white blood cells that are normally found in small numbers in the body.  The presence of a relatively large number of eosinophils is called eosinophilia.  Eosinophilia is a sign of inflammation in the body.  Eosinophilia occurs in a wide range of medical conditions, including infections (especially by parasites), asthma, hay fever, and allergies.  Acute eosinophilic pneumonia is an inflammation of the lungs characterized by eosinophilia, a relatively rapid onset, and often a rapid progression to acute respiratory distress syndrome.

 

d.  The EPICON case definition for AEP is an illness of less than a month’s duration that includes fever, and a cough or shortness of breath, and signs of pneumonia (infiltrates) on chest x-ray.  In order for the pneumonia to be classified as definite acute eosinophilic pneumonia, eosinophils must be detected in fluid recovered from bronchoalveolar lavage (BAL) or lung biopsy procedures. Patients with pneumonia who do not undergo BAL or biopsy but have an elevated number and percentage (>10%) of eosinophils in the blood are considered “probable” cases of AEP.  Finally, all known causes of eosinophilia (allergies, etc.) and acute infection must be excluded for all cases of AEP. 

 

e.  Cigarette and cigar samples from the theater were analyzed and found negative for ricin, strychnine, picrotoxinin, lobeline, diquat, paraquat, and the standard Food and Drug Administration pesticide residues.  Several patients examined at Walter Reed Army Medical Center after recovery showed no signs of a condition called hypersensitivity pneumonitis. 

 

 

LATEST RECAP:

 

The most recent AEP patient from the USCENTCOM AOR was diagnosed in June 2004.  This investigation has also identified three cases of AEP among military personnel not deployed to the USCENTCOM AOR; all were new-onset smokers.  These include one Marine who became ill while undergoing his 2-week annual Reserve training at Fort Hood (July 2004), and two Soldiers stationed in Korea (July 2003 and October 2004).  The October 2004 case died in Japan (enroute to Tripler Army Medical Center from Korea).

 

                                                                              
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Chicken Hawk Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 4:54am

Very interesting, did WHO actually say " There will be no phase 4, We will go straight to pandemic"?

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Covering their preverbal butts cause we should already be at a phase 4 should have been there months ago...So lets just skip the phases and leave everyone till the last minute...dang time to change preparness scenario...

They know if they went to phase 4 or to the 5 people would start isolating themselves and would not show up for work...so now they will wait till its knocking on your door, no moral thought for anyone,s lives in this...

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Chicken Hawk Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 5:34am

I would still like to know if this was actually said by WHO or is this just an assumption. I don't have time to read thru the whole article this morning as I have to go to work, but I was just curious as to whether this is a fact or just speculation.  If this were to blow up overnight then obviously it would go straight into pandemic.

And why would WHO try to cover their butt on anything? Wouldn't they want the world to know to step it up in preparation? If they didn't, isn't that defeating their whole purpose as the World Health Organization and all of the work that they have been doing?  What would they gain from not going to the next phase?

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Post Options Post Options   Thanks (0) Thanks(0)   Quote virusil Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 5:38am
we are on a cross roads,people wake up,and prep please,please
ignorance.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote elbows Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 5:39am
This thread makes no sense to me, where does it say they wont change the level?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 5:40am
Originally posted by Chicken Hawk Chicken Hawk wrote:

I would still like to know if this was actually said by WHO or is this just an assumption. I don't have time to read thru the whole article this morning as I have to go to work, but I was just curious as to whether this is a fact or just speculation.  If this were to blow up overnight then obviously it would go straight into pandemic.

And why would WHO try to cover their butt on anything? Wouldn't they want the world to know to step it up in preparation? If they didn't, isn't that defeating their whole purpose as the World Health Organization and all of the work that they have been doing?  What would they gain from not going to the next phase?

 

Cause they should have put it up to phase for long time ago...they knew there were H2H clusters...

Fluprepper can you give us the URL to the PDF file that contains this information please...

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They say that Who's decision to change the phase of pandemic alert is expected to trigger a number of cascading actions by countries. Possibly including travel restrictions and border closures.

 

That phase of PANDEMIC alert means the start of a pandemic 

There is no mention of an in between. If I am wrong I am sorry. It just says the above. It doesn't actually mention any other phase of alert.

http://www.who.int/csr/disease/avian_influenza/guidelines/Ra pidResponse_27%2001.pdf

 

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Post Options Post Options   Thanks (0) Thanks(0)   Quote elbows Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 5:58am
Eh? Changing the phase of pandemic alert means putting up the level, whether it be to 4,5 or whatever. So I dont know what you are talking about.

As for triggering a cascade of actions by countries, well thats the entire point of having an alert system.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote sweets Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 6:09am

Ok I read this article before and it looks to me as though they added this to the old report. Anyone?

 

Next steps and timeline

Period between 1 February and 6 March 2006

• Initial discussions with regions and countries

• Identification and recruitment of key project staff, including secondments

• Identification of all key issues and scope of work

• Drafting of a detailed core plan, key protocols and standard operating procedures

6 to 10 March 2006

• Global meeting in Geneva to reach agreement on all fundamental concepts and

critical procedures. Prior to this meeting, the WHO working group will have

contacted or visited each relevant member state.

Period between 11 March and 1 April 2006

• Finalization of all details

• Incorporation of comments from countries and other partners

By 1 May

• Development of teaching materials

• Recruitment of a training faculty.

WHO pandemic influenza draft protocol for rapid response and containment – 27 January 2006

14

May and onwards

• Start training of staff for the rapid response teams

Funding

Sufficient initial funding has been promised to start this project and additional funding is

anticipated.

O

ther issues

• A very strong communications component will be needed to explain the project both

as it develops and once it is activated. Although communications were not covered

in this proposal, future drafts will include this component.

• Given that some potential actions such as quarantine and movement restrictions can

raise questions related to individual liberties, ethicists will be brought into the

planning process.

• At this time, many specific questions exist about some foreseen actions, such as the

size and extent of quarantine and social distancing. As this proposal moves forward,

some modeling groups will be recruited to provide input to help address certain

logistics issues in detail.

• International field teams will be deployed to a country only at the request of that

country. WHO will use the GOARN mechanism to assemble and deploy a team of

responders. Each team will be configured to address the tasks at hand, but a typical

team may consist of a 1) a team leader, 2) epidemiologists (some with clinical

backgrounds), 3) laboratory testing experts; 4) communication specialists (media and

community relations specialists); 5) data base managers; 6) infection control

specialists, 7) a logistician; and 8) an ethicist. If quarantine is instituted, the team

will be split with some members within the quarantine zone and others outside the

zone.

• Each country is expected to provide extensive input on how several steps and

activities will be handled within the country on practical issues, such as the

management of antiviral drugs once they arrive within the country. While WHO can

provide guidance on general requirements, each country will be expected to address

details such as import clearance, transportation from airport to outbreak location,

local storage of the antiviral drugs and other stockpiles items, and how use of

antiviral drugs can occur in the absence of national licensing.

As far as the jump from 3-5 ????

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WHO experts draw up pandemic flu battle plan

* Dead swans in Poland had H5N1 strain g Cats in Austria test H5N1-positive

GENEVA: The global spread of bird flu is unprecedented and the threat of a human pandemic will not go away, but the world is not totally defenceless, the World Health Organisation (WHO) said on Monday.

Speaking at the start of a three-day meeting of experts called to sharpen the global response to any human outbreak, the WHO’s top influenza official said the first thing would be to try to stamp it out before it really took hold.

If that failed, the next move would be to attempt to curtail its spread and avoid the high death toll and economic devastation that a full blown pandemic would bring, said Margaret Chan. “When a notoriously unpredictable virus like the influenza virus is given unprecedented opportunities, we must be prepared to see some surprises,” she said in opening remarks to the meeting at the WHO headquarters in Geneva.

“But we are not without defences, if we act collectively right now,” she added.

Some 30 epidemiologists, virologists, and laboratory experts will take part in the talks, along with health officials from affected countries. “During the first years of the 21st century, concern about the spread of infectious diseases has escalated very rapidly, following the emergence and international spread of SARS and now the looming threat of infectious disease from potential pandemic influenza,” WHO special adviser on avian influenza Margaret Chan told the health experts.

“Events in recent weeks justify that concern. H5N1 avian influenza has spread to affect wild and domestic birds in 17 new countries in Africa, Asia, Europe and the Middle East,” she added.

The technical meeting is due to work on a “protocol for rapid containment and response”, to ease the detection of the first signs of a possible new, more deadly and infectious strain of flu in humans that could spread swiftly around the world.

The original draft of the plan, one of a series to coordinate international action, was first released in January.

But the outcome of the latest three-day discussion behind closed doors is not expected to be available until March 15, WHO spokesman Dick Thompson said.

WHO epidemiologist Keiji Fukuda said: “We hope by the later part of the summer to initiate some of the practical steps”.

A Polish laboratory confirmed Monday that two swans found dead in the north of the country were infected with the H5N1 subtype of bird flu, which can be transmitted to humans, swelling to nine the number of EU countries with the deadly viral strain.

“Yes, we have confirmed that it is definitely H5N1. We are following all the procedures in force in the European Union. The samples will now be examined by the (EU) reference laboratory in Weybridge (England),” the deputy director of Pulawy laboratory, Jan Zmudzinski, told AFP.

The H5N1 bird flu virus has been found in “two or three cats” in the southern Austrian province of Styria, the province’s health authorities were cited Monday as saying by Austrian media.

The cats infected with the H5N1 virus, which can be lethal to humans, are still alive, Hans Seitinger, Styria’s agricultural representative was quoted as saying by the Austria Press Agency and ORF radio.

The virus was found after tests were conducted on the cats by the Health and Food Safety Agency, Seitinger said. agencies

 

http://www.dailytimes.com.pk/default.asp?page=2006%5C03%5C07 %5Cstory_7-3-2006_pg4_4

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 6:32am
The global spread of bird flu is unprecedented and the threat of a human pandemic will not go away
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Chicken Hawk Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 7:00am

Even though some people think it should have been upgraded to phase 4-5 a long time ago, apparently WHO doesn't think so or they would have already done it.     

 I think Elbows said it best,As for triggering a cascade of actions by countries, well thats the entire point of having an alert system."

I still don't see why they would be trying to cover their butts, it's not like bird flu is a big secret. It would defeat their whole purpose for exsisting if they were trying to keep things quiet.  I think they are doing a great job.  I don't think we would be as informed about Avian Flu without them, so I am trusting that they will continue to keep us informed.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote virusil Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 7:18am

trusting...........we will be dead meat,

well not me,since i got my silver bullet

ignorance.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Chicken Hawk Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 7:54am
and so do I , I might be trusting but I am not stupid
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 8:21am

Originally posted by elbows elbows wrote:

Eh? Changing the phase of pandemic alert means putting up the level, whether it be to 4,5 or whatever. So I dont know what you are talking about.

As for triggering a cascade of actions by countries, well thats the entire point of having an alert system.

 

I think that they are somewhat acknowledging that thier system is not truly reflective of the actual health threat to humans.  The wording of thier system is inadequate.

It is like saying there is increased evidence of an avalanche coming down the mountain, soon we will raise the level to "Avalanche".

I think they are acknowledging the realization that, at this point in the game, ANY increase from "little evidence" is massively significant and in reality is tantamount to "avalanche", whether it is way up on the mountain or not.   Once this thing starts showing "increased" evidence of H2H, it essentially *IS* H2H.    In some ways, I feel better about seeing this paper.

They are being as prudent as possible: it *could* (unlikely) just disappear or  become mild.  On the other hand, I take it between the lines that they realize that if it does get worse, there's no point in wasting time talking about "increasing evidence"

On the other hand, that scares the sh*t out of me.

For me, this is almost trigger-pulling time...and, after I let it sink in a while, could very well be.

 

 

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For me, this is almost trigger-pulling time...and, after I let it sink in a while, could very well be(quote)

I feel the gitter bugs crawling on my spine cord also..and no that not the few beers I had last night

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Time is GMT + 8 hours
Posted: 06 March 2006 2114 hrs

Experts draw up pandemic flu battle plan at WHO


GENEVA : Experts began meeting at the World Health Organisation Monday to refine plans for rapid detection and containment of a potential global flu pandemic, amid concern about the spread of highly pathogenic H5N1 avian influenza in birds.

"During the first years of the 21st century, concern about the spread of infectious diseases has escalated very rapidly, following the emergence and international spread of SARS and now the looming threat of infectious disease from potential pandemic influenza," WHO special adviser on avian influenza Margaret Chan told the health experts.

"Events in recent weeks justify that concern. H5N1 avian influenza has spread to affect wild and domestic birds in 17 new countries in Africa, Asia, Europe and the Middle East," she added.

The technical meeting is due to work on a "protocol for rapid containment and response", to ease the detection of the first signs of a possible new, more deadly and infectious strain of flu in humans that could spread swiftly around the world.

The original draft of the plan, one of a series to coordinate international action, was first released in January.

But the outcome of the latest three-day discussion behind closed doors is not expected to be available until March 15, WHO spokesman Dick Thompson said.

WHO epidemiologist Keiji Fukuda said: "We hope by the later part of the summer to initiate some of the practical steps".

The spotlight is currently focusing on the H5N1 bird flu which since 2003 has killed 94 people who are thought to have been infected by birds, according to WHO data.

Despite fears that the virus could mutate when mixed with human influenza, it has not so far developed the capacity for person to person transmission.

"From the media reporting, you do get a sense of confusion between avian influenza, seasonal influenza and pandemic influenza, and we don't need this confusion," Chan said.

"We are not having pandemic influenza yet. This is still primarily a
disease of birds," she emphasised. "We are not without defences if we act correctly right now."

There were warnings at the beginning of the meeting in Geneva that a potential pandemic might derive from another strain.

"Even if H5N1 stays in its animal box, this plan would be an investment for the future," Angus Nicoll of the European Centre for Disease Prevention and Control explained.

One of the key challenges for experts is how to define the early warning signs of a pandemic strain of influenza.

Under the latest proposals seen by AFP - which are expected to change - a combination of signals are under consideration, including clusters of respiratory disease and changes in the human influenza virus.

Epidemiological signs could occur with a cluster of more than 20 cases of moderate or severe respiratory illness, and possible deaths, in a "specific setting" such as a family, hospital or school, or a limited area such as a village, according to the draft.

Other factors for concern could include clusters in several locations, the presence of H5N1 or concurrent seasonal influenza.

Countries would be urged not to wait for the completion of a full
investigation into suspected signs and alert the WHO within 24 hours.

That would prompt a series of detailed steps involving the UN health agency, including possible containment measures, and potentially leading to "targeted" quarantines. - AFP/ch


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Copyright © 2006 Agence France Presse. All rights reserved.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 9:18am

There is something else going on aswell.

 Look at the above article. She says that there are warnings at the beginning of the meeting in Geneva that a potential pandemic might derive from another strain.

In Muskrats article she says we must be prepared to see some surprises.

This is the second time this week that I have have read that there might be some surprises!

 I am going to do some digging later. Known viruses around are.

H3N8 virus which recently jumped species from horses to dogs in the states causing kennel cough symptoms and pneumonia.

September 1998 in Malaysia emerged Nipah virus newly recognised zoonotic disease causing high fatality in humans.

Adenovirus Chicken ebola.

Any ideas?

 

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 9:20am
Look at soem of the posts Rick has done the one I moved to speculation about something that it early...wow some strange times...
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 9:23am

Hantavirus in Brazil 2004 H2H not known in rats and mice.

Ebolahaemorrhagic fever in Congo and Uganda which is more lethal than Sars!

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Post Options Post Options   Thanks (0) Thanks(0)   Quote fafhrd Quote  Post ReplyReply Direct Link To This Post Posted: March 07 2006 at 9:26am
In the nomenclature doesn't "strain" indicate, for instance, HPAI vs LPAI rather than a different genotype?
I had a little bird,
his name was Enza;
I opened the window,
and influenza.
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