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Tracking the next pandemic: Avian Flu Talk

UK: Poultry worker has H7 bird flu

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    Posted: April 28 2006 at 10:37am
    UK poultry worker 'has bird flu'
A poultry worker has contracted the H7 strain of bird flu in the form of conjunctivitis, the Health Protection Agency has confirmed.
It is believed the worker was infected through close contact with birds at the Witford Lodge Farm in North Tuddenham, in Norfolk which had the disease.

H7 has no relationship to the deadly H5N1 strain which has killed over 100 people, mainly in South Asia.

The Health Protection Agency said the worker has no other symptoms.

A spokesman for the Department for Environment, Food and Rural Affairs said the strain seen at the farm is the H7N3 form of bird flu.

It is not highly infectious.

The strain was last seen in the UK in 1979.

The 34,000 birds on the infected farm will still be slaughtered, and a 1km exclusion zone will remain in place.

Defra said further tests were being carried out to confirm scientists' initial findings.

The World Health Organization says not all H5 or H7 strains are severe, but their ability to mutate means their presence is "always a cause for concern"

http://www.birdflubreakingnews.com/templates/birdflu/window.php?url=http%3A%2F%2Fnews.bbc.co.uk%2F1%2Fhi%2Fuk%2F4956224.stm

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Post Options Post Options   Thanks (0) Thanks(0)   Quote chargingbear Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 10:45am
Originally posted by Sniffles Sniffles wrote:

    UK poultry worker 'has bird flu'
A poultry worker has contracted the H7 strain of bird flu in the form of conjunctivitis,




interesting infected through the eye mucus

humm african horse sickness in the news
http://www.capeargus.co.za/index.php?fSectionId=49&fArticleId=3219918
 i
nfected through the eye mucus membrane




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Post Options Post Options   Thanks (0) Thanks(0)   Quote Scotty Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 11:55am
The announcement about the chickens appeared on Wednesday. Today, Friday, the announcement was made that a poultry worker was infected with H7. I wonder what the incubation periods are in both chickens and humans.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote unpathedhaunts Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 2:05pm
Bird flu strain is not H5N1

IAN CLARKE, SHAUN LOWTHORPE

28 April 2006 21:51

East Anglia's £1bn poultry industry tonight breathed “a massive sigh of relief” as a bird flu outbreak was confirmed as mild so no large scale restrictions are needed.

One poultry worker on the mid Norfolk farm where it was detected has contracted the H7N3 strain of the disease in the form of the eye infection conjunctivitis.

The man - who is thought to have had very close contact with infected birds - did not need to go to hospital and is at home “in good health” receiving anti-viral drugs.

But there was overwhelming relief within the industry which employs 40,000 people that the “nightmare scenario” of a foot and mouth-style shutdown of large parts of the countryside has been avoided.

The government's chief veterinary officer Dr Debby Reynolds revealed the outbreak at Whitford Lodge Farm, North Tuddenham, near Dereham, was the H7N3 strain which last occurred in the UK in 1979. It has no relation to the H5N1 virus which has killed 100 people worldwide.

Some further laboratory tests are needed over the next week on samples taken from the Tuddenham farm, but Dr Reynolds said indications were that it was a low-pathogenic virus - which eases fears over the disease spreading to other farms.

Nigel Joice, regional chairman of the National Farmers' Union poultry board, said: “We can breathe a huge sigh of relief. Bird flu is not good news but this is the best news we could have had in this situation.

“We are reassured that large scale restrictions will not be needed.”

He said the swift actions after the outbreak was reported had ensured the virus could be isolated - unlike an outbreak in Holland in 2003 when authorities were slow to respond and 32 million birds were slaughtered.

Heather Peck, Defra's regional operations director, said: "It's certainly good news that it's H7N3 - that's a very important piece of news.

"This means that the restrictions required around the infected premises are extremely less.

"Have we identified every possible case in the country? We don't know. That's why we are doing increased surveillance.”

The precautionary mass cull of all 35,000 birds at Tuddenham should be completed on Saturday.

And it was claimed tonight that the farm could be operating again within a month once a thorough clean up had been carried out.

The farm - which has a one kilometre restricted zone around it - is owned by Banham Poultry.

Tests are being carried at all 30 Banham sites in the region including tracking the movements of staff on and off the poultry farms in a bid to pinpoint the origin of the outbreak.

Some movement restrictions are starting to be lifted.

Officials said the most likely cause of the outbreak was “faecal contamination” with people “not being as rigorous in their disinfectant processes as they should have been.”

The “be sensible but don't panic” message was tonight re-iterated in Norfolk as 1800 reassurance leaflets were delivered to homes in villages near Tuddenham.

The insistence that “Norfolk is open for business as usual” was also repeated as the bank holiday weekend began.

The man with conjunctivitis has the low pathogenic H7N3 strain of avian flu which does not transmit easily from person to person.

He reported his illness on Thursday and people he lives with have been given advice by health officials.

Between 60 and 70 other people, including members of the State Veterinary Service and poultry workers had been issued with antiviral drugs as a precaution.

Swabs and blood tests have also been taken from some and their health has been monitored.

During the 2003 outbreak of H7 bird flu in Holland about eight people got infections such as conjunctivitis. One vet died and that remains the only death attributed to H7.

Dr Maria Zambon, director of the Health Protection Agency's Influenza Laboratory, said the risk posed to the general public is “extremely limited.”

“It is important to remember that H7 remains largely a disease of birds.

Two ambulances were called to the Tuddenham farm during today to take away workers, but they are thought to be unrelated to the outbreak.

One suffered an epileptic fit and the other is thought to have recently had an operation.

Mrs Peck said vets were investigating three reports of dead chickens being found elsewhere in the county - but stressed there was no link with the Banham outbreak and such reports were to be expected at a time of heightened concern.

Two of the reports are thought to involve backyard hens, while she could not confirm if the third incident took place on a farm.

Mid Norfolk MP Keith Simpson said it was “good news” that it was the H7 strain rather than the more serious virus.

Alan Hay, director of the Medical Research Council's World Influenza Centre, said the H7N3 infection in people was not unusual but could only be passed through close contact.


The national Defra helpline for anyone with queries or concerns about bird flu is 08459 335577.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote unpathedhaunts Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 2:10pm
H7N3 Bird Flu Confirmed in UK Poultry Worker

Recombinomics Commentary
April 28, 2006

the worker, who does not want to be named, has the H7N3 strain of bird flu which is not highly infectious

The above comments acknowledge that H7N3 has caused at least one case of conjunctivitis in Great Britain. This case is not a surprise. H7 infections in poultry frequently result in conjunctivitis cases in human contacts. The most recent example was in British Columbia in 2004 where several poultry workers developed conjunctivitis from H7N3. However the H7N7 outbreak in the Netherlands in 2003 produced over 80 cases of conjunctivitis in poultry cullers.

However, a sensitive assay was developed to detect H7 antibodies and hundreds or thousands of culler contacts had H7 antibodies, indicating human-to-human transmission of H7 is efficient. The cases had mild symptoms or were asymptomatic. However, a veterinarian developed pneumonia and died. This is the only reported fatality from bird flu linked to a serotype other than H5N1. The H7N7 isolated from the fatal case had PB2 E627K.

E627K was first reported in H5N1 from birds in the 16 isolates from Qinghai Lake, almost 1 year ago. All Qinghai H5N1 PB2 sequences to date have also had E627K. This polymorphism is liked to enhanced polymerase activity at lower (33 C) temperatures. It is also associated with increased virulence in mammals.

Although the has been only one report of H5N1 in the UK, the Qinghai strain has been detected throughout Europe, raising serious issues about the sensitivity of the assay in the UK. The UK surveillance failed to detect significant infections by H5N1 or low pathogenic serotypes, even though over 7000 birds were tested. The surveillance failed to detect any H7 infections.

The co-circulation of H7 and the Qinghai strain of H5N1 is cause for concerns. E627K could be acquired by H7N3 via recombination or reassortment. This acquisition would likely increase virulence in an H7 which is probably readily transmitted between humans.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 2:17pm
Chief vet responds to bird flu test results
28/04/2006

Following preliminary laboratory results indicating that the Avian Influenza virus isolated in a Norfolk poultry unit is a low pathogenic H7 strain the Chief Veterinary Officer for Scotland, Charles Milne, welcomed the rapid response to this incident.

These results, obtained by the Veterinary Laboratory Agency, do not affect the proposal to lift the restrictions imposed following the identification of Highly Pathogenic H5N1 Avian Influenza in a swan at Cellardyke.

Mr Milne said:

"The preliminary finding of low pathogenic H7 Avian Influenza in Norfolk has no direct implications for the poultry industry in Scotland.

"However, this incident highlights the importance of good surveillance and we continue to encourage poultry keepers to be vigilant for signs of disease in their flock and to maintain good biosecurity.

"We remain on course to lift the 10 kilometre Wild Bird Surveillance Zone on 1 May. It is intended to lift the wider Wild Bird Risk Area at the same time subject to any further developments and a veterinary risk assessment."

The Wild Bird Surveillance and Wild Bird Risk Area are expected to be lifted at 00.01 hours on 1 May 2006.

http://www.scotland.gov.uk/News/Releases/2006/04/28211703
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Commonground Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 3:14pm
I'm just going to throw this speculation out there. You don't suppose that this is what Niman was referring to as "Spring Bride"? H5 & H7 combining?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Ironstone Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 3:26pm
Commonground, i think Dr. Niman said the Spring Bride would be a pig with H1N1 and the aquisition would be G228S.  That had to do with the binding site on the virus and would enable H5 to infect easier.  He did make a comment about H7 that used to be in Germany and  to the belief it would have been much worse, but records said it had been eradicated from the area.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 3:39pm
"The man with conjunctivitis has the low pathogenic H7N3 strain of avian flu which does not transmit easily from person to person.

He reported his illness on Thursday and people he lives with have been given advice by health officials."

From Sniffles' article above.  So how come the birds started dying Wed before last, over a week ago, but they couldn't get the test results till last Wed, over a week later? Yet the person's test was validated after 24 hours.  Beth
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Scotty Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 3:54pm
Economical with the truth?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Commonground Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 4:13pm
Thanks Ironstone, I didn't know that.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 5:07pm
World News

The Times April 29, 2006

Eye infection diagnosed in bird flu farm worker

By Valerie Elliott, Countryside Editor
A POULTRY worker has contracted conjunctivitis from birds on the Norfolk farm infected with a low pathogenic strain of H7 avian flu virus.

The man, who has not been named, suffered red irritable eyes yesterday. He was immediately treated and is now said to be in good health. His family have been examined but show no signs of this mild infection.

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The worker, employed by Banham Poultry UK Ltd, is one of 70 people who are also being treated with Oseltamivir, the antiviral drug, to protect them from bird flu. No one else has shown symptoms of sickness.

The incident yesterday was not linked with an avian flu outbreak and medical experts said that the dust and dry conditions in chicken sheds make workers more prone to conjunctivitis.

Debby Reynolds, the Government’s chief vet, last night confirmed that the virus infecting 35,000 birds at Whitford Lodge farm in North Tuddenham, near Dereham, was the less virulent H7N3 flu strain. This was last seen in Britain in 1979 and has no resemblance to the lethal H5N1 virus.

A cull of the chickens was under way, after being delayed by 24 hours because of an error that required a new firm to be called in to assist.

The H7N3 virus is endemic in poultry in parts of America and has also been reported recently in chickens in Canada and Italy. It is not easily passed between humans or birds.

However, Dr Reynolds has ordered extra checks on bird samples to make certain that there is no evidence of the highly pathogenic strain of the virus that could decimate commercial poultry flocks. A 1 km (2/3 ml) surveillance zone is in place around the infected Witford Lodge farm and movement restrictions on all birds and eggs are in place on 30 other premises in Norfolk and Suffolk owned by Banham.

Three years ago, during the outbreak of H7 Asian flu in the Netherlands, 88 people suffered conjunctivitis and of these 10 per cent also had severe respiratory problems.

Government vets are still investigating the cause of the outbreak at the Norfolk farm, but suspect that the virus arrived from another infected farm or from wild birds.

http://www.timesonline.co.uk/article/0,,3-2156511,00.html
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 5:19pm
Bird flu confirmed in farm worker
Dead birds
Culled chickens have been removed from Witford Lodge Farm
A poultry worker is suffering from conjunctivitis after contracting the H7 strain of bird flu, the Health Protection Agency has confirmed.

The person was infected through close contact with birds at the Witford Lodge Farm in North Tuddenham, Norfolk, which had the disease.

H7 has no relationship to the deadly H5N1 strain which has killed over 100 people, mainly in South Asia.

The Health Protection Agency said the worker has no other symptoms.

It is important to remember that H7 avian flu remains largely a disease of birds
Dr Jonathan Van Tam, HPA

It added that the worker, who does not want to be named, has the H7N3 strain of bird flu which is not highly infectious and last seen in the UK in 1979.

The worker has not required hospital treatment.

He or she was given the antiviral drug Tamiflu as a precautionary measure on Thursday as soon as the HPA was told about the outbreak.

The strain is not easily passed from poultry to people, or from person to person, the HPA said.

"In almost all cases of human H7 infection to date, the virus has only caused a mild disease," it said in a statement.

"Therefore, the risk to the general public in this outbreak is extremely limited."

Conjunctivitis causes red, sore, itchy eyes and the worker has no respiratory symptoms.

To date, most human cases of H7 avian influenza have presented with conjunctivitis only.

Cull

An unconfirmed number of other workers are already taking the same drug to prevent the illness.

They are also being offered the seasonal flu jab to prevent the H7 virus from mixing with any human flu viruses that may be circulating.

Nose and throat swabs and blood tests are also being taken from the other workers, and their health is being closely monitored.

Close contacts of the infected worker are also being given advice and preventative medication as appropriate.

Dr Jonathan Van Tam, a flu expert at the HPA, said: "It is important to remember that H7 avian flu remains largely a disease of birds.

"The virus does not transmit easily to humans, as evidenced by the small number of confirmed infections worldwide to date.

"Almost all human H7 infections documented so far have been associated with close contact with dead or dying poultry.

"The threat to human health posed by H7 avian influenza viruses remains very low despite the recent developments in Norfolk."

Alan Hay, director of the Medical Research Council's World Influenza Centre, said: "These sporadic human infections do happen in the case of H7 when people are in very close contacts with birds.

"You have to keep this in context, people in close contact have to take sensible precautions such as wearing eye masks and gloves but this is not an infection that other people should be concerned about catching."

The Department for the Environment, Food and Rural Affairs confirmed that the 34,000 birds on the infected farm will still be slaughtered, and a 1km exclusion zone will remain in place.

The World Health Organization says not all H5 or H7 strains are severe, but their ability to mutate means their presence is "always a cause for concern".


http://news.bbc.co.uk/1/hi/uk/4956224.stm

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 5:30pm
This is the end of a long article about the outbreak of  human illness from H7N3 in British Columbia. Very interesting.
 
Linkto full article below.
To date, illness in humans from H7 subtypes differs markedly in severity from that of avian influenza H5N1 (12). Their lower virulence should not be inferred to indicate lower pandemic potential since subclinical or mild infections may have greater opportunity through surreptitious spread to reassort and through mutation to become more virulent. A compilation and detailed overview of the protective measures used in all avian influenza outbreaks would help to estimate the actual risk to persons and populations. Recommendations for precautions that are both necessary and reasonable during future poultry outbreaks could then be refined.

Ms. Tweed is an epidemiologist at the British Columbia Centre for Disease Control. Her main research interests are vaccine-preventable, respiratory, and emerging infectious diseases.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 5:45pm

British farm hand infected by mild strain of bird flu

Experts say the virus detected at the farm is definitely the milder H7 strain of avian flu - not the deadly H5N1 strain that has claimed hundreds of lives in Asia.

Vets were last night continuing to slaughter 35,000 chickens at the farm following the outbreak, detected earlier this week.

Hundreds of people living near the farm were last night sent letters of "reassurance" by local councils. [I wonder what was in the letters].

Meanwhile, a dead swan was discovered yesterday near the East Neuk village of Pittenweem in Fife.

A local schoolteacher who found the swan contacted police. The location is just outside the 3km exclusion zone introduced following the discovery of the deadly strain of bird flu in a swan's carcase in the nearby coastal village of Cellardyke.

The 3km wild bird protection zone, which was put in place on 5 April, was lifted only last weekend.

The Scottish Executive said that the discovery of the H7 strain in Norfolk would not change its plans to lift bird flu restrictions in Scotland from Monday.

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'Don't panic' message over bird flu

Officials have moved swiftly to reassure the public after a poultry worker contracted the H7 strain of bird flu in the form of conjunctivitis.

Letters were being delivered to some 1,800 homes near to the Norfolk farm, as vets continued to slaughter 35,000 chickens after the virus was detected earlier this week.

Both the Health Protection Agency (HPA) and Norfolk County Council stressed the countryside was "open", despite the outbreak in which the worker is thought to have become infected via close contact with poultry.

"We want to reassure residents that all agencies are working together to minimise the impact of the outbreak of the form of avian flu on the local community," said a spokesman for Norfolk County Council.

"A joint letter from the two Chief Executives of the councils is being delivered to about 1,800 homes tonight and over the weekend in North and East Tuddenham, Hockering and Mattishall to reassure local people."

The HPA said the worker reported his illness yesterday, adding symptoms were limited to an eye infection, without respiratory problems.

The infected man, who has not been identified, has the low pathogenic H7N3 strain of avian flu which does not transmit easily from person to person, the HPA said.

Dr Maria Zambon, director of the HPA's Influenza Laboratory, said: "He is in good health. He has a mild illness."

Experts say tests have shown the virus detected at Hockering is the milder H7 strain of avian flu - not the deadly H5N1 strain that has claimed the lives of hundreds of people in Asia.

The risk posed to the general public from the outbreak at Witford Lodge Farm is "extremely limited", the HPA added, and the worker did not need hospital treatment.

http://www.ananova.com/news/story/sm_1822631.html?menu=
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Post Options Post Options   Thanks (0) Thanks(0)   Quote wannago Quote  Post ReplyReply Direct Link To This Post Posted: April 28 2006 at 9:46pm
So there is one outbreak in England, of a lesser BF.  Poultry workers receive antivirals and one worker is infected.

Now, doesn't it seem preposterous that there are absolutely NO human cases in India or Pakistan?

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