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Tracking the next pandemic: Avian Flu Talk

China records new H10N8 bird flu death

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carbon20 View Drop Down
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    Posted: February 14 2014 at 1:22pm

BEIJING — Chinese officials have said a new strain of avian influenza, H10N8, has killed another person, according to a report on Friday by Xinhua, the state news agency. The victim was a 75-year-old man living in Nanchang, the capital of Jiangxi Province, who entered a hospital on Feb. 4 after falling ill. He died on Feb. 8, Xinhua reported.

The first case of human infection involving the strain H10N8 emerged in Jiangxi in December. The infected person, a 73-year-old woman, died from the illness on Dec. 17. Infections among birds had been previously reported. A 55-year-old woman from Jiangxi was hospitalized in January with the same illness. Both women had had contact with live poultry. The man in Nanchang is the third case of H10N8.

Scientists are also concerned about the rapid spread of another strain of avian flu, H7N9. It has already infected about 300 people and infects more each day. A quarter of those infected have died. The first human cases of H7N9 were reported last March.


Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

Marcus Aurelius
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 14 2014 at 1:43pm
sorry same post as Kyle,

this has me a bit more 

INTERESTED...............
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Marcus Aurelius
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 15 2014 at 5:15am
How virulent is this virus?

Columbia University professor and virologist, Vincent Racaniello, PhD writes in his website:

Examination of the viral protein sequences provides some clues about virulence of the virus. The HA protein sequence reveals a single basic amino acid at the cleavage site, indicating that the virus is of low pathogenicity in poultry, like H7N9 virus. The sequence in the sialic acid binding pocket of the HA protein indicates a preference for alpha-2,3 linked sialic acids, typical for avian influenza viruses (human influenza viruses prefer alpha-2,6 linked sialic acids). A lysine at amino acid 627 in the PB2 protein is known to enhance the ability of the virus to replicate at mammalian temperatures; the H10N8 virus has a mixture of lysine and glutamic acid, the residue associated with less efficient replication. The sequence of the M2 protein indicates that the virus is resistant to the antiviral adamantanes. In vitro testing indicated sensitivity to NA inhibitors Tamiflu and Relenza.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 18 2014 at 8:07pm

Pandemic fears still high in Asia as H10N8 bird flu strain emerges

Updated 19 February 2014, 13:49 AEST
Karon Snowdon for Asia Pacific, wires

World health authorities have flagged concerns about a new strain of avian influenza - H10N8 - that has already killed three people in China.

 Officials wearing masks and protective suits pile dead chickens into black plastic bags in Hong Kong on January 28, 2014. (Credit: AFP) 

World health authorities have flagged concerns about a new strain of avian influenza - H10N8 - that has already killed three people in China.

The new strain adds to scientists' concerns over the rapid spread of the H7N9 variant which has infected about 300 people and killed around 75 since March last year.

The three people infected with the H10N8 strain all had contact with live poultry.

Doctors in the region say the virus needs to be closely monitored.

"We know that the pandemic virus, it often comes from animal sources, so we know that the previous influenza virus came either from bird sources or pig sources, so any new animal influenza viruses that affect humans we have to look at very carefully." says Dr Peter Horby, Senior Clinical Research Fellow at the Oxford University Research Unit in Vietnam.

Other regions have been sources of new disease outbreaks too, but the population density of East and South East Asia lead some to describe it as the "hotspot" for serious new infectious diseases.

The close proximity of livestock and people, the nature of markets and now cheap travel and visa free movements between ASEAN states mean a major problem remains.

Even the region's increasing urbanisation can either be an advantage or a problem, despite impressive improvements in health and the lessons learnt in the past decade.

Hong Kong extends ban on poultry imports amid H7N9 fears.

Hong Kong officials said Tuesday they were extending for four months a ban on live poultry imports from mainland China to guard against H7N9.

The city imposed a 21-day ban in January and culled some 20,000 chickens after the virus was found in one batch of imported chickens.

Health minister Ko Wing-man told reporters there are plans to set up a facility where imported poultry can be quarantined to ensure they are disease-free before being sent to market.

After four months "we will liaise with mainland authorities about the supply of live poultry to Hong Kong", he said.

Before the import ban, local birds were mixed with those from mainland China in the city's only wholesale market, in the Cheung Sha Wan district.

Since December Hong Kong has reported five human H7N9 infections, of whom three have died.

"Complete transformation" in regional outbreak response

Dr Horby urges there be no letting up in building capacity to deal with biological threats.

Once a virus becomes transmissible from person-to-person, it's likely to spread very quickly.

But he says the region's surveillance and response measures have improved drastically in recent years.

"You only have to look at the difference from SARS to the emergence of H7N9 in China. It's been a complete transformation really.

"With H7N9 influenza, the Chinese have been incredibly quick to identify the problem, to investigate it, to inform regional and global authorities and also to cooperate with other countries in investigating the problem, monitoring it and reporting it," he said

ABC/AFP

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