Tracking the next pandemic: Avian Flu Talk |
H10N8 Hits Humans in China |
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Medclinician2013
Valued Member Joined: September 17 2013 Location: Carmel Status: Offline Points: 9020 |
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Posted: February 05 2014 at 6:38pm |
http://www.newscientist.com/article/dn24981-threatwatch-mother-virus-of-chinas-deadly-bird-flu.html#.UvL0-uKUEw8
Exactly 10 years after H5N1 bird flu exploded across south-east Asia, the virus is still widespread, and has been joined by new killer types of bird flu. Human cases of H7N9 flu are surging in south-east China, and a new type of bird flu, H10N8, has claimed its second human victim, in the same region. Now it seems that all of these viruses stem from a single, mother virus. Targeting it might stop it from spawning new, deadly viruses in the future. Few people have heard of H9N2, but this virus was crucial in giving rise to the three dangerous bird flu viruses that have emerged so far in China – H5N1, H7N9 and H10N8. None of these viruses has yet evolved the ability to spread readily in people and potentially trigger a pandemic – although we know H5N1 can, and H7N9 and H10N8 seem similar. But even if those viruses never go rogue, their cousins might, because the real problem is their common ancestor, which endowed them with the genes that make them dangerous. The enabler"H9N2 is the enabler, the one to worry about," Robert Webster of St. Jude Children's Research Hospital in Memphis, Tennessee, told New Scientist. Bird flu is usually a gut infection in ducks, but H9N2 has evolved into a benign respiratory virus in chickens that has spread across Eurasia. When multiple flu viruses infect the same host, they can swap genes. They may be named for their various H and N surface proteins, but H5N1, H7N9 and H10N8 all got some or all of their "internal" genes from H9N2. |
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Medclinician - not if but when - original
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Medclinician2013
Valued Member Joined: September 17 2013 Location: Carmel Status: Offline Points: 9020 |
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I would say that a death in 2 days is rather ominous. That is fast.
http://offgridsurvival.com/scientists-warn-of-new-bird-flus-h10n8-pandemic-potential/ So far only two people have been infected, with one of them dying within two days of falling ill. While these numbers don’t seem alarming, scientists say the genetic profile of this strain is very worrying and needs to be closely monitored. comment: What else do we have that can kill that quickly? |
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Medclinician - not if but when - original
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Jen147
Moderator Joined: March 23 2013 Status: Offline Points: 17144 |
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How to make sense of H10N8, H1N1, H7N9, and other bewildering bird flu names
February 6, 2014
H10N8 is the latest bird flu to come out of China and, potentially, decimate humanity like in that Gwyneth Paltrow movie. You may have previously been mortally frightened by news about H1N1, which killed up to 100 million people in 1918 and another 15,000 in 2009 and 2010. Or maybe you’ve been reading about H7N9, which has been connected to just about 100 human deaths and is the cause of a massive poultry cull in Hong Kong this week:
Is H10N8 10 times more deadly than H1N1—or is it eight times, or 80? Not at all. The names refer to the two kinds of spiky protein that influenza A viruses wear on their surfaces, all the better to burrow into the hosts’ cells. H is for hemagglutinin and there are 16 varieties; N is for neuraminidase and there are nine different kinds. All told there are 144 different types of influenza A, from H1N1 to H16N9, all of which are found in birds and some of which are also found in horses, pigs, and humans.
So why do new versions keep popping up to infect humans? That’s where promiscuous virus behavior comes in. The influenza A virus is fond of a little trick known as reassortment, which means that two viruses infecting the same cell can swap genetic components such as hemagglutinin and neuraminidase proteins. So a chicken in China (virtually all new influenza strains arise in southeast and eastern Asia because of the close contact between humans and livestock) that has two known flu types can give rise to a novel third strain.
To complicate matters, a virus can mix and match any of its eight genes—not just the H and N proteins—and can incorporate genetic material from swine, avian, and human flu strains.
In the case of H10N8, only one person has died and another has become sick, making it much too early to issue any apocalyptic warnings. But Chinese and global health authorities are carefully monitoring the virus—especially any indications that it is transmittable between humans, which is when the alarm bells really start going off.
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Johnray1
Valued Member Joined: April 23 2006 Location: United States Status: Offline Points: 8159 |
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Jen147,with the Chinese doing the reporting,how do we know that there have only been 2 cases.? Johnray1
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Jen147
Moderator Joined: March 23 2013 Status: Offline Points: 17144 |
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First death from new bird-flu strain fuels fears of pandemic
Feb. 04 2014
The world’s first death from a new strain of bird flu is sending ripples of concern through the medical community as experts debate whether the virus has the potential to cause a pandemic. Chinese researchers reported in the Lancet on Tuesday that a 73-year-old Chinese woman died in December after contracting the new influenza A H10N8 virus. So far, only two cases have been reported in humans, and there is no indication it can to pass from human to human. But the scientists reported the virus in the 73-year-old woman was a mutated strain, meaning it could be learning to replicate more efficiently in humans. The news is the latest in a string of high-profile reports about emerging avian flu strains and deaths related to seasonal flu that led to heightened demand and subsequent shortages of vaccines in some provinces. But the truth, several experts on infectious diseases say, is that this year’s flu season is relatively normal and no one can predict what virus will lead to the next pandemic. “We, globally, still don’t know enough to say anything intelligent about a pandemic threat,” said Allison McGeer, director of infection control at Toronto’s Mount Sinai Hospital. The predominant strain in Canada this year is H1N1, which caused a global pandemic in 2009. The strain hits people under 65 particularly hard because they have not been exposed to it, unlike many seniors. Reports of numerous deaths of young people in Canada and the United States who contracted H1N1 created an unexpected flurry of demand for the flu shot across Canada. Much of the concern has also centred on H7N9, an avian flu virus that has led to nearly 300 cases in humans in China – 63 of them fatal. This week, the Public Health Agency of Canada told The Canadian Press it is monitoring the situation closely and updating its national pandemic preparedness plan. Last month, officials in Alberta said a woman in that province died after contracting the H5N1 avian flu in China – the first fatal case in North America. One reason so many reports of different flu viruses are emerging is that countries like China have developed comprehensive surveillance systems to track problems and detect viruses as they emerge, Dr. McGeer said. “The harder you look, the more you’re going to find,” she said. John Spika, the Public Health Agency of Canada’s director-general for immunization and respiratory infectious diseases, said the reports of H10N8 represent “no risk” to Canadians. But he added that Canadians should be concerned about the flu every year, not just when new strains or deaths of young people are reported. “Ideally, you know, Canadians would be getting vaccinated at much higher rates every year,” Dr. Spika said. In Canada, 2,298 people had been hospitalized with influenza and 113 flu-related deaths had been reported as of Jan. 25. The actual numbers are likely higher because not every case is tested and confirmed by a laboratory. Every year, between 4,000 and 8,000 Canadians die of the flu. Dr. Spika said that, nationally, the flu season has peaked and numbers are slowly decreasing, although the eastern part of the country still has quite a few cases. |
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Johnray1
Valued Member Joined: April 23 2006 Location: United States Status: Offline Points: 8159 |
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Jen147,thanks for the lecture with pictures. I had forgotten most of this. Johnray1
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Johnray1
Valued Member Joined: April 23 2006 Location: United States Status: Offline Points: 8159 |
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Med,it look like your suspicion that there are more viruses moving around than we are being told about,is correct.Johnray1
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Jen147
Moderator Joined: March 23 2013 Status: Offline Points: 17144 |
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It's exactly as you say... with the Chinese reporting how will we ever really know.
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