H1N1 genetic changes 2013-questions

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   Based on *******Flu Tracker I understand that two major genetic chances need special attention. D225G showed up in Utah this August. I understand that H274Y showed up in Mississippi and Louisiana in November.  D225G means the virus-receptorbinding takes place in the lungs ? (This is a question). H274Y means Tamiflu does not work any longer. Both changes were not around in 2009, if I'm correct-meaning H1N1-virus now are a bigger danger. 
I also inform myself on recombinomics-site. H.Niman will try to find out sequences of newest cases. Am I correct in expecting further changes that might make vaccinations less effective. 

Based on ******* I have the impression that H1N1 was a big problem in Mexico last months, also deadly. Is the virus in the southern US the same virus as in Mexico and Canada ? It will only be a matter of time before this H1N1 will show up in Europe. 

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Dutch Josh Members Profile Send Private Message Find Members Posts Add to Buddy List Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95867	Post Options Post Reply Quote Dutch Josh Report Post Thanks(0) Quote Reply Topic: H1N1 genetic changes 2013-questions Posted: December 20 2013 at 8:14am
	Based on *****Flu Tracker I understand that two major genetic chances need special attention. D225G showed up in Utah this August. I understand that H274Y showed up in Mississippi and Louisiana in November. D225G means the virus-receptorbinding takes place in the lungs ? (This is a question). H274Y means Tamiflu does not work any longer. Both changes were not around in 2009, if I'm correct-meaning H1N1-virus now are a bigger danger. I also inform myself on recombinomics-site. H.Niman will try to find out sequences of newest cases. Am I correct in expecting further changes that might make vaccinations less effective. Based on ***** I have the impression that H1N1 was a big problem in Mexico last months, also deadly. Is the virus in the southern US the same virus as in Mexico and Canada ? It will only be a matter of time before this H1N1 will show up in Europe.
	We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein

Dutch Josh Members Profile Send Private Message Find Members Posts Add to Buddy List Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95867	Post Options Post Reply Quote Dutch Josh Report Post Thanks(0) Quote Reply Posted: December 20 2013 at 8:18am
	Another difference compared to 2009 is the number of other virusses and the increasing resistence of bacteria increasing chances for co-infections. Timing is also not good with Christmas/New Year and school-restarting in January.
	We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein