Click to Translate to English Click to Translate to French  Click to Translate to Spanish  Click to Translate to German  Click to Translate to Italian  Click to Translate to Japanese  Click to Translate to Chinese Simplified  Click to Translate to Korean  Click to Translate to Arabic  Click to Translate to Russian  Click to Translate to Portuguese


Forum Home Forum Home > Emerging Disease Tracking > Avian Flu
  New Posts New Posts RSS Feed - poor vaccine protection against H3N2
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Online Discussion: Tracking new emerging diseases and the next pandemic

poor vaccine protection against H3N2

 Post Reply Post Reply
Author
Message
arirish View Drop Down
Admin Group
Admin Group
Avatar

Joined: June 19 2013
Location: Arkansas
Status: Offline
Points: 37850
Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Topic: poor vaccine protection against H3N2
    Posted: October 13 2017 at 8:05am


Study warns of possible repeat poor vaccine protection against H3N2 in seniors

Low influenza vaccine effectiveness (VE) in seniors against the H3N2 flu strain last season could show the same pattern this season, since H3N2 is still the dominant global strain and current vaccines still contain the same H3N2 component, European researchers warned today in Eurosurveillance.

After analyzing the latest report from the Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE) network, researchers provided final estimates against H3N2 hospitalizations for people age 65 and older for the previous season, which show overall VE of 17% in the group, which is lower than the early estimate of 23.4% reported in February. In people older than 80, VE was especially low, at 13%.

The scientists weren't able to measure VE against 2009 H1N1 and influenza B, because of the small number of cases. VE against those strains is usually reported to be higher.

When they compared findings in people who weren't vaccinated in the 2015-16 or 2016-17 seasons, vaccination in the earlier season seemed to have a modifying effect on effectiveness during the latter season. Though the authors said the results were too imprecise to be conclusive, the results suggest that patients vaccinated in both seasons benefited from residual protection from the earlier season, with no added effect from the 2016-17 vaccine.

Flu vaccine protection against H3N2 is known to be unpredictable, and the I-MOVE reserachers noted that most circulating H3N2 viruses last season were considered antigenically similar to the vaccine virus, though they underwent genetic diversification with the emergence of subclusters within clade 3C.2a and subclade 3C.2a1. In September, the World Health Organization (WHO) vaccine advisors recommended changing the H3N2 component of the Southern Hemisphere's vaccine for the 2018 season.

"Close monitoring of virological surveillance data will be required to prompt early promotion of complementary measures such as the use of antivirals or non-pharmaceutical interventions," the iMove team wrote.

http://www.cidrap.umn.edu/news-perspective/2017/10/news-scan-oct-12-2017

http://eurosurveillance.org/content/10.2807/1560-7917.ES.2017.22.41.17-00645
Buy more ammo!
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down