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Tracking the next pandemic: Avian Flu Talk

Worse -Hybrid of the H9N2 and H3N2 strains-manmade

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    Posted: March 22 2009 at 2:00pm

Lab creation of worse Avian strain with possible bioweapon application


Tuesday, March 17, 2009 by: David Gutierrez, staff writer

http://www.naturalnews.com/025860.html

NaturalNews) Even as governments and health experts around the world have been focusing on the threat of a pandemic of the H5N1 strain of avian flu, another dangerous strain known as H9N2 has gone mostly ignored, according to a study published in the journal PLos ONE.

comment: the almost buried publication is not that recent but highly informative and found here http://www.plosone.org/article/info:doi/10.1371/journal.pone.0002923

"Our results suggest that the establishment and prevalence of H9N2 viruses in poultry pose a significant threat for humans," the researchers wrote.

Of three known species of influenza virus, two of them regularly infect humans. The third species, influenza A virus, primarily affects birds and is also known as bird flu. Among hundreds of strains of influenza A, the World Health Organization says that only four have ever been known to infect humans: H5N1, H7N3, H7N7 and H9N2.

H5N1 has attracted the most attention due to its extreme virulence and high death rate - of 385 humans known to have been infected with the virus since 2003, 243 have died. The virus is widespread in both domestic and wild bird populations, giving rise to fears that it could mutate into a form more easily transmissible to and between humans.

But H9N2 can also cross from birds to pigs, humans and other animals, and has infected at least four Hong Kong children to date. In its current form, the virus causes only mild symptoms. In the current study, however, researchers found that a single mutation was enough to make H9N2 more infectious and virulent, but also to enable it to cross directly between infected ferrets.

Ferrets react to influenza similarly humans,
and are often used as an animal model for the disease.

Hybridization of the H9N2 and H3N2 strains also resulted in a more pathogenic and easily transmitted flu. Researchers believe this could occur if a single organism is infected with both strain simultaneously

comment: Pack theory - j. aka MC PI NIH research project sub

Neither of the laboratory-produced strains was able to spread through the air and could only spread by touch, similar to colds.

However courtesy of CIDRAP -

WHO picks new B strain for 2009-10 flu vaccine

Lisa Schnirring * Staff Writer

Feb 13, 2009 (CIDRAP News) – Because of a suboptimal match between this year's flu vaccine and circulating influenza B viruses, the World Health Organization (WHO) has recommended changing one of the three strains used in flu vaccines for the Northern Hemisphere next fall and winter.

comment: once again they missed - in the last 7 years, in 5 years the vaccine given missed at least one of the highest occurring flu bugs.  MC

The WHO's choices for the two influenza A strains remain the same as last year, according to new reports published on the WHO Web site this week. The agency recommended keeping the influenza A/H1N1 and A/H3N2 variants used in this year's vaccine, both of which are labeled Brisbane strains.

The influenza B component of this year's flu vaccine was from the Yamagata lineage, but the proportion of strains from the Victoria lineage continues to increase and has become predominant in many countries, the WHO said. The US Centers for Disease Control and Prevention's (CDC's) most recent flu surveillance report, for the week of Feb 1 through 7, said that of 78 influenza B viruses that were characterized, 55 belonged to the Victoria lineage.



Sources for this story include: www.reuters.com.

Medclinician
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