China's New Outbreak

China's new outbreak shows signs the virus may be changing and it's making it harder to diagnose changes before it spreads.  Gird your loins for the second wave, people!

https://www.bloombergquint.com/coronavirus-outbreak/china-sees-signs-new-cluster-carries-virus-longer-than-in-wuhan 

Here is the big question:  If people have had the Covid 19 in the first wave are they going to get it again in the second wave?    China could be a good way to find this out IF THEY ARE HONEST about  who is sick and how many.

'And mine are girt also.

FluMom.  With a new virus, we just do not know.  The most likely senario is that those who have had it in wave 1 will get a slightly milder infection in wave 2 than the previouslu uninfected, but that is far from certain.  They could be automatically on course for the kawasaki-type-disease seen in some children currently, or a cytokine storm, or even no difference from the reactions of the uninfected.  Personal genetics could also spread the differences out so we see all four reactions in different peoples.

Sorry, I could not give you a straighter answer.

Your gird your loins comment made me laugh this morning while drinking coffee and coffee is not meant to go through your nose, yet it did. LOL Don't hear that saying very often.

Oh we are going to have a second wave no doubt but when is the question.  I am not going back to work at my school but hope to be able to work with kids on line.  I did this in the spring and it works ok.  The schools in Denver Metro Area are doing a "Hybrid" learning.  One day in the school with only 9 students and 1 teacher in the room once a week,  no gym no cafeteria (eat in the classroom bag lunch) so all kids get one day a week with their teacher.  The rest of the days will be online learning with the teacher and I hope some of the paraprofessionals.     This is the model across all of Denver Metro Schools.  If the virus gets bad then they will all go back to all online.

No one knows what is going to happen,  I am glad they are opening now to see how this goes.  It would be worse to do opening in August or September because that is when most schools start and if opening is bad then it will not affect the start of school.   No matter what if you have 2 working parents one will have to be home at least 4 days a week.    No more babysitting services 5 days a week.

From the article; (China had the B-type, now has to deal with a A or C type-PNAS study-maybe no mutations needed)

Officials now believe that the new cluster stemmed from contact with infected arrivals from Russia, which has one of the worst outbreaks in Europe. Genetic sequencing has showed a match between the northeast cases and Russian-linked ones, said Qiu.

[url]https://www.pnas.org/content/117/17/9241[/url];

In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia.