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Tracking the next pandemic: Avian Flu Talk

EATING OUT IS A BAD IDEA

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    Posted: November 11 2020 at 4:39pm

As if any of you failed to work this out already, the data is in:


How to stop restaurants from driving COVID infections

US mobile data suggests restaurants, gyms and cafes can be COVID hotspots — and reveals strategies for limiting spread. 

In cities worldwide, coronavirus outbreaks have been linked to restaurants, cafes and gyms. Now, a new model using mobile-phone data to map people’s movements suggests that these venues could account for most COVID-19 infections in US cities.

The model, published in Nature today, also reveals how reducing occupancy in venues can significantly cut the number of infections.

The model “has concrete pointers as to what may be cost-effective measures to contain the spread of the disease, while at the same time, limiting the damage to the economy”, says Thiemo Fetzer, an economist at the University of Warwick in Coventry. “This is the policy sweet spot.”

Mobility data

To predict how people’s movements might affect viral transmission, the research team input anonymized location data from mobile-phone apps into a simple epidemiological model that estimated how quickly the disease spreads. The location data, collected by SafeGraph, a company based in Denver, Colorado, came from 10 of the largest US cities, including Chicago, Illinois; New York; and Philadelphia, Pennsylvania. It mapped how people moved in and out of 57,000 neighbourhoods to points of interest, such as restaurants, churches, gyms, hotels, car dealers and sporting-goods stores for 2 months starting in March.

When the team compared the model’s number of infections in Chicago neighbourhoods between 8 March and 15 April with the number of infections officially recorded in those neighbourhoods a month later, they found that the model had accurately predicted confirmed case numbers.

“We are able to faithfully estimate the contact network between 100 million people for every hour of the day. That is the secret ingredient we have,” says Leskovec.

Venue hot spots

The team then used the model to simulate different scenarios, such as reopening some venues while keeping others closed. They found that opening restaurants at full capacity led to the largest increase in infections, followed by gyms, cafes and hotels and motels. If Chicago had reopened restaurants on 1 May, there would have been nearly 600,000 additional infections that month, while Opening gyms would have produced 149,000 extra infections. If all venues were open, the model predicts that there would have been 3.3 million additional cases. 

But capping occupancy for all venues at 30% would reduce the number of additional infections to 1.1 million, the model estimated. If occupancy was capped at 20%, new infections would be reduced by more than 80% to about 650,000 cases.

“The study highlights how real-time big data on population mobility offers the potential to predict transmission dynamics at unprecedented levels of spatial granularity,” says Neil Ferguson, an epidemiologist at Imperial College London.

The mobility data also suggest why people from poorer neighbourhoods are more likely to get COVID-19: because they are less able to work from home, and the stores they visit for essential supplies are often more crowded than in other areas. The average grocery store in poorer neighbourhoods had 59% more hourly visitors per square foot, and visitors stayed on average 17% longer than at stores outside those areas. Leskovec says that people living in these areas probably have limited options to visit less crowded stores, and as a result, a shopping trip is twice as risky as it is for someone from a wealthier area.

But Christopher Dye, an epidemiologist at the University of Oxford, says these mobility patterns need to be validated with real-world data. “It is an epidemiological hypothesis that remains to be tested. But it is a hypothesis that is well worth testing,” he says.

Global trend

Broadly speaking, Fetzer says, the modelling study corroborates much of what has been learnt from contact-tracing studies worldwide, which have identified restaurants, gyms, choir practices, nursing homes and other crowded indoor venues as locations of superspreader events, where many people are infected at one time. 

Last month, Fetzer published a report showing how a UK government programme called Eat Out to Help Out, in which restaurant meals were subsidized during August, led to a huge surge in restaurant visits and accounted for up to 17% of new COVID-19 infections that month.

But restaurants might not be hot spots everywhere. Contact-tracing data from Germany has found that restaurants were not the primary source of infection in that country, says Moritz Kraemer, who models infectious diseases at the University of Oxford, UK. That might be because it can be difficult to identify the source of an infection using contact-tracing data. Although the model’s prediction of overall infection rates in cities was validated with real-world data, Kraemer says more detailed contact-tracing data will be required to test whether the model correctly identified the actual location of infections.

Leskovec says that all models have some amount of error. But as many of its predictions align with observational data, he adds, there is no reason to think that it wouldn’t work at smaller scales.

If the model is found to accurately predict the risk of visiting specific locations, health officials could use it to fine-tune social-distancing policies, says Ferguson.



Source:  Nature

                                                        

doi: https://doi.org/10.1038/d41586-020-03140-4



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Post Options Post Options   Thanks (0) Thanks(0)   Quote WitchMisspelled Quote  Post ReplyReply Direct Link To This Post Posted: November 11 2020 at 6:05pm

Cuomo is rolling back restaurant seating to 25%, Restaurants and gyms will have a 10pm curfew and gatherings are again limited to 10.  He's saying there will be more roll-backs if and as infections rise further. 

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Post Options Post Options   Thanks (1) Thanks(1)   Quote CRS, DrPH Quote  Post ReplyReply Direct Link To This Post Posted: November 11 2020 at 11:29pm

I don't know why the possibility of fecal/oral transmission continues to be downplayed.  This would explain a lot of transmission related to food service/restaurants/establishments.

https://www.sciencedirect.com/science/article/abs/pii/S0016508520305710

In as few as 3 months, coronavirus disease 2019 (COVID-19) has spread and ravaged the world at an unprecedented speed in modern history, rivaling the 1918 flu pandemic. Severe acute respiratory syndrome coronavirus-2, the culprit virus, is highly contagious and stable in the environment and transmits predominantly among humans via the respiratory route. Accumulating evidence suggest that this virus, like many of its related viruses, may also be an enteric virus that can spread via the fecal–oral route. Such a hypothesis would also contribute to the rapidity and proliferation of this pandemic. Here we briefly summarize what is known about this family of viruses and literature basis of the hypothesis that severe acute respiratory syndrome coronavirus-2 is capable of infecting the gastrointestinal tract and shedding in the environment for potential human-to-human transmission.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote EdwinSm, Quote  Post ReplyReply Direct Link To This Post Posted: November 12 2020 at 12:16am

Originally posted by CRS, DrPH CRS, DrPH wrote:

 I don't know why the possibility of fecal/oral transmission continues to be downplayed.  


May be those in authority don't want to admit that Shit happens.  Especially in places were we eat.  


I may joke about that, but it is the route by which I contacted hepatitis (in a developing country), so I know the seriousness of it.  I had what was considered a 'mild case' and was only off work six weeks.   I have never felt so weak and after getting well enough to get up could barely walk.  

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Post Options Post Options   Thanks (0) Thanks(0)   Quote CRS, DrPH Quote  Post ReplyReply Direct Link To This Post Posted: November 12 2020 at 11:51am

Originally posted by EdwinSm, EdwinSm, wrote:

Originally posted by CRS, DrPH CRS, DrPH wrote:

 I don't know why the possibility of fecal/oral transmission continues to be downplayed.  


May be those in authority don't want to admit that Shit happens.  Especially in places were we eat.  


I may joke about that, but it is the route by which I contacted hepatitis (in a developing country), so I know the seriousness of it.  I had what was considered a 'mild case' and was only off work six weeks.   I have never felt so weak and after getting well enough to get up could barely walk.  

Sorry to hear that, Hep A is a nasty virus!  

The SARS outbreak in 2003 was facilitated by malfunctioning plumping in an apartment building in Hong Kong, and we are able to track SARS CoV2 in sewage effluent, so it is very logical that the virus is spread just like Hep A, norovirus and other fecal bugs.  I believe that is why the early cruise ship outbreaks were so bad, despite attempts to isolate passengers etc.  The crew preparing and distributing food likely contaminated the food, plates etc. of passengers with fecal matter (or nasal secretions), leading to an explosion of cases.


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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: November 12 2020 at 2:00pm

ABC News: Inside the sewage lab: How your wastewater is guiding Australia's COVID-19 response.

https://www.abc.net.au/news/2020-11-13/covid-sewage-testing-makes-inroads-in-coronavirus-response/12875682

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Post Options Post Options   Thanks (0) Thanks(0)   Quote CRS, DrPH Quote  Post ReplyReply Direct Link To This Post Posted: November 15 2020 at 9:51pm

Originally posted by carbon20 carbon20 wrote:

ABC News: Inside the sewage lab: How your wastewater is guiding Australia's COVID-19 response.

https://www.abc.net.au/news/2020-11-13/covid-sewage-testing-makes-inroads-in-coronavirus-response/12875682

Excellent, thank you C!  We are also doing this monitoring in Tucson Arizona USA, it is fascinating work! 

https://west.arizona.edu/news/2020/08/wastewater-testing-uarizona-stops-coronavirus-spread-garners-national-attention

This is all evidence for a fecal/oral transmission component, which I do not find mentioned hardly at all in the public health literature.

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