Tracking the next pandemic: Avian Flu Talk |
My 5 year old grandson in serious condition COV - Event Date: March 02 2020 - April 03 2020 |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Posted: March 20 2020 at 4:33am |
For those millions in this war who still think this isn’t a danger to the young and healthy get your head out of your**** |
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EdwinSm,
Moderator Joined: April 03 2013 Status: Offline Points: 24065 |
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((((((((((______)))))))))))) ___________ usk (above is a virtual coronavirus hug, ie keeping a distance) |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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We are worrying with you, Usk. Chin up pal! |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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BabyCat
V.I.P. Member Joined: January 26 2020 Status: Offline Points: 15175 |
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Wow. It's affecting so many, closer and closer to all of us. Prayers for your family. |
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FluMom
Adviser Group Valued Member Since 2006 Joined: February 03 2020 Location: Colorado Status: Offline Points: 14695 |
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So sorry, Prayers. |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Thank you. We can’t go see him. His dad is in ICU with him. Just as support. They’re starting him my grandson on cloniquine the anti malary drug and steroids. He just got symptoms two days ago and they said his immune system went into hyperdrive |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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Please keep us updated. |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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ME163
Admin Group Joined: September 16 2006 Status: Offline Points: 4552 |
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Usk, my heart goes out to you. I am praying for you.. Keep in touch. |
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hoosiermom22
V.I.P. Member Joined: January 21 2020 Location: Indiana Status: Offline Points: 1225 |
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Praying 🙏🏻 |
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Tabitha111
Adviser Group Joined: January 11 2020 Location: Virginia Status: Offline Points: 11640 |
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To my fellow Virginian....hugs to you and so very sorry. |
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'A man who does not think and plan long ahead will find trouble right at his door.'
--Confucius |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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Steroids depress the immune system. It sounds as if an overactive immune system is the problem this time. |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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Tabitha111
Adviser Group Joined: January 11 2020 Location: Virginia Status: Offline Points: 11640 |
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I think I just read a news story on your grandson on facebook! Oh my.... |
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'A man who does not think and plan long ahead will find trouble right at his door.'
--Confucius |
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Sheep Lady
V.I.P. Member Joined: February 06 2020 Status: Offline Points: 3215 |
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Prayers that his little body responds to treatment. Praying for you all Usk. |
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Sheep Lady
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JellyMama
V.I.P. Member Joined: February 25 2020 Location: Texas Status: Offline Points: 375 |
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Please God, take care of this little boy and make him well. |
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ViQueen24
Adviser Group Joined: May 14 2013 Location: Verona, PA Status: Offline Points: 12270 |
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Prayers for you all Usk. Keep us updated. |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Read this resesrch pn Primates and SARs. Hope it works Chloroquine is a potent inhibitor of SARS coronavirus infection and spreadMartin J Vincent, Eric Bergeron, [...], and Stuart T Nichol AbstractBackgroundSevere acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available. ResultsWe report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations. ConclusionChloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds. Keywords: severe acute respiratory syndrome coronavirus, chloroquine, inhibition, therapyBackgroundSevere acute respiratory syndrome (SARS) is an emerging disease that was first reported in Guangdong Province, China, in late 2002. The disease rapidly spread to at least 30 countries within months of its first appearance, and concerted worldwide efforts led to the identification of the etiological agent as SARS coronavirus (SARS-CoV), a novel member of the family Coronaviridae [1]. Complete genome sequencing of SARS-CoV [2,3] confirmed that this pathogen is not closely related to any of the previously established coronavirus groups. Budding of the SARS-CoV occurs in the Golgi apparatus [4] and results in the incorporation of the envelope spike glycoprotein into the virion. The spike glycoprotein is a type I membrane protein that facilitates viral attachment to the cellular receptor and initiation of infection, and angiotensin-converting enzyme-2 (ACE2) has been identified as a functional cellular receptor of SARS-CoV [5]. We have recently shown that the processing of the spike protein was effected by furin-like convertases and that inhibition of this cleavage by a specific inhibitor abrogated cytopathicity and significantly reduced the virus titer of SARS-CoV [6]. |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Further in vivo evaluation of this drug against 2019-nCoV infection is recommended. Notably, two compounds remdesivir (EC50 = 0.77 μM; CC50 > 100 μM; SI > 129.87) and chloroquine (EC50 = 1.13 μM; CC50 > 100 μM, SI > 88.50) potently blocked virus infection at low-micromolar concentration and showed high SI (Fig. 1a, b). Cite this article Wang, M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res 30, 269–271 (2020). https://doi.org/10.1038/s41422-020-0282-0 |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Sorry when I get upset I do research to help calm myself It looks like these docs know what to try first |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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There is no known cure just things to try |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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Thank you, Usk. We are still with you. |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Thank you all for your support it is so very much appreciated |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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I (and I know I'm not alone in this) only wish I could do more, Usk. |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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Newbie1A
Adviser Group Joined: January 26 2018 Location: Alberta Status: Offline Points: 11180 |
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Usk, my heart hurts for you, prayers for fast recovery for your grandson & strength for you and all who love him. Long distance hugs to you and yours - please keep us all updated as best you can. |
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If it's to be - it's up to me!
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kaye kaye
V.I.P. Member Joined: February 27 2020 Location: ohio Status: Offline Points: 3290 |
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Praying for a fast recovery for the little guy. |
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keep the joy
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KiwiMum
Chief Moderator Joined: May 29 2013 Status: Offline Points: 29680 |
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I'm so sorry to hear about your grandson, what terrible news. He's in my prayers for a full and speedy recovery. |
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Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts.
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WitchMisspelled
Adviser Group Joined: January 20 2020 Status: Offline Points: 17170 |
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Usk, he's in my prayers for a full and speedy recovery. Sending cyber hugs your way. |
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pheasant
Admin Group Joined: May 20 2006 Location: Florida Status: Offline Points: 9851 |
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My family's praying as well for you all. |
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The only thing we have to fear, is fear itself......FDR
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jacksdad
Executive Admin Joined: September 08 2007 Location: San Diego Status: Offline Points: 47251 |
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I’m so sorry. Please let us know how he’s doing. We’re all thinking of him. |
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"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary. |
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roni3470
Adviser Group Joined: August 30 2006 Location: Colorado Status: Offline Points: 5390 |
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I am so sorry to hear. Praying for you and your family! |
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NOW is the Season to Know
that Everything you Do is Sacred |
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BeachMama
V.I.P. Member Joined: January 25 2020 Location: Southwest US Status: Offline Points: 3080 |
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Usk, I know I can say nothing to make you truly feel better — but I am SO sorry. My family and I will be praying for your grandson every single day. |
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Gdeb
V.I.P. Member Joined: January 24 2020 Location: Colorado Status: Offline Points: 880 |
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Prayers for a speedy recovery. |
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Turboguy
Admin Group Joined: October 27 2007 Status: Offline Points: 6079 |
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He should be able to make it through. Little kids are extraordinarily resilient. Good that he is in the hospital and fairly early on in this. When he makes it through he might have missed the worst of this. Wish him and his parents luck. |
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Liberals claim to want to give a hearing to other views, but then are shocked and offended to discover that there are other views. - William F. Buckley
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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All your prayers and thoughts of support and HYDROXYCHLOROQUINEWorked. He turned the corner last night breaking the 104 fever and his lungs except for right lower lobe is clear !!! He should come home today to his house. Dad is still symptom free and so his is mom and older brother Thank you again. They also used short z pac which I think is zythromycin and prednisone short 5 day course. Big sigh of relief!! |
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Usk
V.I.P. Member Joined: January 26 2020 Location: Virginia Status: Offline Points: 7325 |
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Just saw it was you Turboguy. How are you? We were worried you had not posted. So glad you are back! |
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Gdeb
V.I.P. Member Joined: January 24 2020 Location: Colorado Status: Offline Points: 880 |
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Great news, Usk!! |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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So glad! Glad for my friend (you Usk) glad for the little boy and glad for everyone as the treatment works for everyone it appears. Good new at last! |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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WitchMisspelled
Adviser Group Joined: January 20 2020 Status: Offline Points: 17170 |
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I am so happy for you and your family Usk! This is great news! |
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EdwinSm,
Moderator Joined: April 03 2013 Status: Offline Points: 24065 |
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Happy News. |
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LCfromFL
Adviser Group Joined: August 17 2006 Location: United States Status: Offline Points: 1614 |
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This is FABULOUS news, Usk!!! Praying for continued recovery for him and protection for the rest of your family. |
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Sheep Lady
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Praise God! Still praying for you all! |
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Sheep Lady
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FluMom
Adviser Group Valued Member Since 2006 Joined: February 03 2020 Location: Colorado Status: Offline Points: 14695 |
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Praise The Lord, he is better! |
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BabyCat
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mwbab
V.I.P. Member Joined: February 15 2012 Status: Offline Points: 480 |
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That is good news glad he is improving |
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CST
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Prayers, for you little one. |
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Lakeman5
V.I.P. Member Joined: March 19 2020 Location: IL Status: Offline Points: 480 |
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So glad he is getting beter! |
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