Tracking the next pandemic: Avian Flu Talk |
COVID-19 Detection Dogs |
Post Reply |
Author | |
AandEM
V.I.P. Member Joined: March 06 2020 Location: IN Status: Offline Points: 1245 |
Post Options
Thanks(0)
Posted: July 28 2020 at 2:39pm |
We could use some good news. This would be a game changer for schools, if it were in fact a practical development. |
|
Tabitha111
Adviser Group Joined: January 11 2020 Location: Virginia Status: Offline Points: 11640 |
Post Options
Thanks(0)
|
By Scott Weese on July 28, 2020 A colleague asked me about scent detection dogs the other day. My response was that I hadn’t heard much after all the initial buzz, which might suggest things weren’t going well. Here’s a breakdown and some commentary. They collected saliva samples and respiratory secretions from hospitalized COVID-19 patients, and healthy people that were PCR negative.
They didn’t test samples for other human coronaviruses (those that cause the common cold). It’s a potential limitation but I don’t think it’s a big deal. They also don’t explain where they got their negative samples (were dogs detecting SARS-CoV-2 or something unique to the positive sample population, like being from a hospital). Clear description of the study populations is critical and it’s somewhat lacking here. Because of the potential susceptibility of dogs to this virus, samples were inactivated prior to exposing them to the dog. That’s a reasonable step but raises more issues of practicality and how dogs would be used (exposed directly to a high risk patient specimen vs detection of someone walking by). Eight dogs were trained using standard methods. They had a 2 week habituation process for the training system, then had 5 days of training until their rate of detection was greater than what would be expected by chance alone. They then started the study Small sample size but reasonable for a proof-of-principle study. The ability of dogs to detect positive samples increased over time. For a screening test, we’d actually want the reverse….high sensitivity at the expense of specificity. That would mean you’d detect most positives. A low sensitivity and high specificity means you run into fewer hassles with false positives but miss more positive people. The fact that 17% of samples from people hospitalized with active COVID-19 were called negative is a concern for picking up positives in less severely affected people and detection from less voluminous and close samples (e.g. detection directly from someone walking by vs detection from an aliquot of secretions from the lower airways). I’d file this in the ‘interesting but preliminary’ folder. Anything that can help identify infectious people is useful. If dogs could be part of that, great. They’d have to be able to do it from a distance (since a handler and dog getting very close to large numbers of people might cause more problems than they fix). In my perfect world…. A dog would be parked at the entrance of a school, office building, subway…. It would be able to detect infected people from a short distance. It would signal when it detected a positive person. That person would (discretely) be pulled aside for testing, which would (again, in my perfect world) be done quickly, right there. If positive, the person would be told right away and sent home. If negative, they’re good to go (maybe wondering why they smell like a coronavirus). Overall, it’s an interesting and useful preliminary study. ......
|
|
'A man who does not think and plan long ahead will find trouble right at his door.'
--Confucius |
|
Post Reply | |
Tweet
|
Forum Jump | Forum Permissions You cannot post new topics in this forum You cannot reply to topics in this forum You cannot delete your posts in this forum You cannot edit your posts in this forum You cannot create polls in this forum You can vote in polls in this forum |