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PANDEMIC ALERT LEVEL
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Now tracking the new emerging South Africa Omicron Variant

pandemic breakfast

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Dutch Josh View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 13 2022 at 12:01am

DJ, 

-A lot of info on "the international situation"...wars-in latest news. Since it also affects economies, healthcare "the international situation" has lots of pandemic links. 

YES-Refugees may bring/transfer lots of diseases..NO It is not a reason to "kill refugees" -most "civilized western countries" have seas,rivers desserts doing the killing for them...Tens-of-thousends of refugees die that way each year...NATO/Western wars since 1945 most likely killed more people then were killed in the second world war...from Vietnam to Iraq...and the killing goes on...

Of course there is also economic warfare [url]https://en.wikipedia.org/wiki/Poland_and_the_euro[/url] or https://en.wikipedia.org/wiki/Poland_and_the_euro ; In the 2015 Polish parliamentary election, the winning party became the eurosceptic Law and Justice, which opposes euro adoption. On 13 April 2019 at a convention, Jarosław Kaczyński, the leader of Law and Justice Party (PiS) stated: "We will adopt the euro someday, because we are committed to do so and we are and will be in the European Union, but we will accept it when it is in our interest".[38] 

He came forth with a declaration, according to which the euro wouldn't be introduced until Poland's economy catches up with Western economies.[39] In his view Poland should accept the euro only when the national economy will reach 85% of GDP per capita of Germany.[40] Later on Jarosław Kaczyński and premier Mateusz Morawiecki maintain that convergence to euro at this point would be harmful for Poland

DJ Polish GDP has to reach 85% of German GDP and introduction of the Euro has to serve Polish interests...well we may be on our way with German economy close to collapse...Ukraine is supposed to join the EU...so the Euro was planned to become Ukraine currency one day...EU economy "saved" by a "cheap Euro" as compensation for high energy costs...who will pay for that ? Well EU citizens may face close to hyperinflation...the US may be on the same road...

Of course-without an economy you can not have healthcare..."Saving the economy" did allready bring the CoViD-pandemic out of control...Healthcare capacity may "collapse" under the weight of economic collapse and wars...making pandemics even worse...

-[url]https://www.coronaheadsup.com/asia/japan/japan-far-higher-ratio-of-people-dying-after-moderate-covid-infections/[/url] or https://www.coronaheadsup.com/asia/japan/japan-far-higher-ratio-of-people-dying-after-moderate-covid-infections/

Japan says an increasing percentage of people are dying after developing moderate symptoms of COVID-19.

Japan’s National Center for Global Health and Medicine says an increasing percentage of people are dying after developing moderate symptoms of COVID-19. It also says many of them had pre-existing conditions that worsened after they became infected.

The center says a smaller percentage of COVID-19 patients has been developing serious pneumonia in Japan as the vaccination rate increases, while more have died because the coronavirus causes their pre-existing conditions to worsen.

Deaths from Covid in Japan are continuing to breach record highs even though the seventh wave of cases started to decline on the 24th August 2022.

DJ [url]https://www.worldometers.info/coronavirus/weekly-trends/[/url] or https://www.worldometers.info/coronavirus/weekly-trends/ Japan cases -25% from 943,707 last week to 706,770 cases last 7 days...No doubt 8th wave will start within a month or so...

[url]https://www.thailandmedical.news/news/are-the-new-sars-cov-2-variants-circulating-in-europe-more-neuropathogenic-with-a-modified-pathogenesis-brain-and-liver-issues-on-the-rise[/url] or https://www.thailandmedical.news/news/are-the-new-sars-cov-2-variants-circulating-in-europe-more-neuropathogenic-with-a-modified-pathogenesis-brain-and-liver-issues-on-the-rise DJ-Statistics (also a.o. from Taiwan) point that way...

Much more info on [url]https://www.coronaheadsup.com/category/coronavirus/[/url] or https://www.coronaheadsup.com/category/coronavirus/ and [url]https://www.thailandmedical.news/articles/news[/url] or https://www.thailandmedical.news/articles/news ...

-MPX [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory needs updates...problem may be with countries not providing new numbers...(latest from september 9...maybe later on newer info post-weekend...?)

DJ; On Thursday, Los Angeles County, California, health officials confirmed the death of a man recently diagnosed with monkeypox. This brings the number of fatalities with confirmed monkeypox infection to two in the United States. On August 30, Harris County, Texas, reported the first such death in the US in a severely immunocompromised individual.

why this has to come from WSWS ?








Just in time for school starting. ⬆️ hospitalizations for severe pediatric respiratory illness. Including EV-D68 which can also cause Acute Flaccid Myelitis (AFM) a rare neurological condition similar to polio.

and

Roland Baker 2.0

@RolandBakerIII
 · 
CDC: Severe Respiratory Illnesses Associated with Rhinoviruses and/or Enteroviruses Including EV-D68 – Multistate, 2022 https://emergency.cdc.gov/han/2022/han00474.asp?ACSTrackingID=USCDC_511-DM89761&ACSTrackingLabel=HAN%20474%20-%20General%20Public&deliveryName=USCDC_511-DM89761

DJ...we are on our way to healthcare collapse...governments should do all they can to stop this....

-One of my major concerns is the availability of medication and care. Delay in care-because that care was dealing with (chronic) CoViD cases-did cost(tens of ?) thousends of lives worldwide...In many ways healthcare has been overstretched for over two years...In some settings over 10% of health care workers are "ill" for a longer time...from getting infected with a disease to burn-out...

Present global healthcare strategies in most countries are destroying public health...

A part 2 later on today...

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 13 2022 at 1:48am

In part 1 I discussed the economic decrease of healthcare capacity-while pandemic pressure (a.o. aging, wars, refugees) is increasing healthcare demand...

Part 2,








New short paper with : We estimate that Covid-19 illnesses have reduced the US labor force by ~500,000 workers & provide the first representative estimates of Covid’s direct labor supply effects. Paper: https://nber.org/papers/w30435

DJ, long term healthissues related to pandemic diseases and vaccines/medication are growing fast and show much more in "social" sectors with more contacts/spread, care, education, security...








Goldman economists see China persisting with Covid Zero even after its big political meeting

DJ, "the west" is trying to force other countries to follow their denialism on pandemics for economic/profit reasons...

Ryan Hisner

@LongDesertTrain
 · 
Today I discovered an extraordinary microlineage of BA.2.3. What makes it extraordinary? A colossal genetic saltation (10 spike mutations) combined with striking geographic spread for a very small number of sequences (just 4 so far). 1/25 https://github.com/cov-lineages/pango-designation/issues/1013
Show this thread

DJ, I did give up on trying to follow "new variants"...[url]https://outbreak.info/situation-reports[/url] or https://outbreak.info/situation-reports has 620 "Omicron-sub-variants" growing high speed...

[url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time UK now self-reported 1,583,585 cases of "active" CoViD...sep 2 was just over 1,489,200 cases...








I learned *so much* about PAPRs (Powered Air Purifying Respirators) today. I hadn’t given them much thought until now, but they certainly do sound effective & preferable to N95/elastomeric in longer term high-risk situations, like inpatient post-op recovery for instance.

DJ...in practice those that want better ventilation can not pay for it, those that can pay for it often refuse to do so...


U.S. COVID deaths in past 12mos continues to rank the highest . The number of precious lives we’ve lost in 2.5 years exceeds the number of American combat deaths in every war since 1775.  Having COVID? Don't spread it pls. The #immunocompromised needs 😷protection.

See also [url]https://twitter.com/TogetherWeMask/status/1568595352302796801/photo/1[/url] or https://twitter.com/TogetherWeMask/status/1568595352302796801/photo/1 ...India statistics may be "weak"....

'Understaffed and Overworked': Thousands of Minnesota Nurses Go on Strike

and

Sometimes you hit a point where you either change or self-destruct. I believe healthcare has reached this point.

DJ...due to "economic pressure" "politics" in lots of countries go for spending cuts on public healthcare....with another CoViD wave on its way in many places...








Ok here we go. This one was sequenced in México City by the INMEGEN Institute. Centaurus family just arrived. We are in the exit phase of the 5th wave, so it is possible that BA.2.75 or its daughters, ignite the 6th wave soon.

and 

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 13 2022 at 11:20pm

.......DJ......

On this page twitter-post are problematic, in latest news-nuclear war "ksc" is harrassing post that goes against his/her views...

[url]https://halturnerradioshow.com/index.php/en/news-page/world/reports-germany-halts-all-covid-19-vaccines-license-put-on-hold[/url] or https://halturnerradioshow.com/index.php/en/news-page/world/reports-germany-halts-all-covid-19-vaccines-license-put-on-hold ...when I read this claim, Germany would investigat vaccine complications-halt all vaccinations for at least two weeks-I expect other sources to provide more info...DW has nothing about it...[url]https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/913781-covid-19-vaccine-dangers-side-effects-controversy?view=stream[/url] or https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/913781-covid-19-vaccine-dangers-side-effects-controversy?view=stream (with lots of "not so good sources" ) has nothing about it...https://twitter.com/JackKid65506134  as the only source ? 

In the HT link a short clip-with an English voice over-German spoken RKI person not telling that much...[url]https://www.rki.de/EN/Home/homepage_node.html[/url] or https://www.rki.de/EN/Home/homepage_node.html 

DJ-So for now my conclusion...fake news...without any sources. Since another vaccination-booster round is starting also "anti vax" info is increasing...Since I am NOT an expert I try to stay informed...For now my view;

-Vaccines did save maybe up to millions of lives

-At least some vaccines may have more healthissues then the producers claimed to expect...

-Longer term healthissues of (some) vaccines a ????...since I am "old" maybe for myself not the main point...

-Vaccines NEVER were expected to stop getting infected/spread the virus-goal is to limit disease/severity...

Will COVID-19 vaccines stop the pandemic?


It is likely that SARS-CoV-2, the virus that causes COVID-19, will continue to circulate and evolve. It is not possible to predict how infectious or severe new variants of the virus will be. It is therefore very important to achieve and maintain high vaccination coverage across all communities and population groups, at national and international levels. Vaccination remains a key component of the multi-layered approach needed to reduce the impact of SARS-CoV-2.

26 apr. 2022

DJ

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 13 2022 at 11:43pm

DJ...tech problems with inserting that ECDC-link...statistics indicate number of "reported CoViD deaths within 4 weeks after a positive CoViD test"decreased since the start of vaccinations worldwide...However excess death-numbers going up around the globe...

Besides the vaccines itself-you also need to have a "vaccine strategy" [url]https://www.ecdc.europa.eu/en/covid-19/questions-answers/questions-and-answers-vaccines[/url] or https://www.ecdc.europa.eu/en/covid-19/questions-answers/questions-and-answers-vaccines ..One problem is (E)CDC communication is not always clear...

In the US the idea that "vaccinated did no longer need masks" in my opinion was "unwise"....

Mask are part of the Non Pharma Interventions...Vaccines, anti-virals are part of the Pharma Interventions...DJ; Some "big pharma" made statements that during the pandemic they would not go for profits...In my opinion governments, WHO should demand such a basic idea...You do NOT make profits out of a global disaster...but well, some companies go for pandemic profits...

A lot of their research was tax-funded, all of their sales are tax funded...most of profits going to shareholders-often in a position where they also have influence on strategies to limit this pandemic...

Because if you put the start of this CoViD pandemic -based on what is now detected- one could claim this pandemic is around 3 years going on...WHY ???

Politics/"media" going for claims that "the pandemic is over"....statistics simply indicate CoViD is only getting worse...

[url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory Only Ireland and Peru did have recent updates...From a "science perspective" not relating MPX to the underlying CoViD pandemic is anti science...

The Northeast & Midwest are above their respective Delta peaks. Let’s keep doing nothing. It’s working well.

US wastewater/sewage...


BA.2.75 is picking up 346, 356, 444, 452, 486, 490 It’s mutating FAST.

DJ...very likely to become ONE of several dominant sub-variants of CoViD...Recent studies indicate people may catch more then one sub-variant when they get infected...Oral/nasal testing may miss a lot of the virus infection all over the body...(It is NOT a "lung-virus"!!!)

Maryn McKenna

@marynmck
 · 
Announcement by the CDC and the WHO that enough poliovirus has been found circulating in NY, with enough genetic changes, to cause the US to be added to the list of countries with active circulation of vaccine-derived virus. A remarkable, disturbing moment.
Show this thread

DJ...another recent finding is-YES CoViD infection is resulting in weaker immunity...(DJ-Vaccinations itself result in the body building up immunity...during that process vaccinated people may be more vulnerable for infections ??? Also vaccines in older people may offer less protection because also their immune system is not that strong...). 

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 13 2022 at 11:58pm

Part 2 (or 3...the tech error resulting in melting part 1 and 2 together...) 

[url]https://www.coronaheadsup.com/health/long-covid/who-at-least-17-million-long-covid-cases-in-europe-so-far/[/url] or https://www.coronaheadsup.com/health/long-covid/who-at-least-17-million-long-covid-cases-in-europe-so-far/ ;

At least 17 million people in the WHO European Region experienced long COVID in the first two years of the pandemic according to the WHO.

New modelling conducted for WHO/Europe by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington’s School of Medicine in the United States shows that in the first two years of the pandemic, at least 17 million individuals across the 53 Member States of the WHO European Region may have experienced post COVID-19 condition, also known as long COVID. In other words, an estimated 17 million people met the WHO criteria of a new case of long COVID with symptom duration of at least three months in 2020 and 2021.

The modelling indicates a staggering 307% increase in new long COVID cases identified between 2020 and 2021, driven by the rapid increase in confirmed COVID-19 cases from late 2020 and throughout 2021. The modelling also suggests that females are twice as likely as males to experience long COVID. Furthermore, the risk increases dramatically among severe COVID-19 cases needing hospitalization, with one in three females and one in five males likely to develop long COVID.

“While there is much we still need to learn about long COVID, especially how it presents in vaccinated versus unvaccinated populations and how it impacts reinfections, this data highlights the urgent need for more analysis, more investment, more support, and more solidarity with those who experience this condition,” said Dr Hans Henri P. Kluge, WHO Regional Director for Europe. “Millions of people in our Region, straddling Europe and central Asia, are suffering debilitating symptoms many months after their initial COVID-19 infection. They cannot continue to suffer in silence. Governments and health partners must collaborate to find solutions based on research and evidence.”

WHO/Europe urges countries to take post COVID-19 condition seriously by urgently investing in research, recovery, and rehabilitation.

World Health Organisation: At least 17 million people in the WHO European Region experienced long COVID in the first two years of the pandemic

DJ...There is not a uniform definition of "long/chronic CoViD" ....Some use still symptoms after 4 weeks after a positive test...in the above study they used 3 months...looking at data for 2020 and (early) 2021...So the number of Long CoVid cases in the WHO Europe region may by now be double ? 

Another point has to be; Are they still dealing with infections, is the virus still in the host/body ? Or are they dealing with organ damage ? 

DJ-In my "view" chronic CoViD is the most widespread form of CoViD-even higher then "active cases"...bad news is that even during the coming new CoViD (winter) wave chronic CoViD cases still may be going up that much resulting that still chronic CoViD numbers will be higher then acute CoViD...

The above study/article also mentions it is not yet clear how good (what) vaccines protect (best) against chronic CoViD...

Given the economic outlook, healthcare being overstretched, the outlook for a lot of chronic CoViD "cases"  (they are people...not just a "statistic") simply is not good...

[url]https://www.coronaheadsup.com/health/long-covid/bc007-long-covid-treatment-petition/[/url] or https://www.coronaheadsup.com/health/long-covid/bc007-long-covid-treatment-petition/ ;

A new petition on Change.org calls on the German government to expedite clinical trials for BC007, a promising potential treatment for Long COVID.

The Change.org petition is here

Press release from Friedrich-Alexander-Universitätm, Erlangen-Nürnberg re BC 007

 

ENGLISH TRANSLATION OF THE PETITION:

BC007 NOW- Chance of a cure for millions of suffering people

Demands

We call on the German government to financially support the approval studies of the company Berlin Cures GmbH for the drug BC 007 and to remove bureaucratic hurdles to enable an accelerated approval process.

We call on the German government to expand biomedical research on long-covid, ME/CFS and post-vaccine syndrome and to increase government funding for further clinical trials and appropriate therapies to at least 100 million euros for an initial period of 24 months.

We call on the German government to expand the long-covid outpatient clinics into interdisciplinary treatment centers, to improve the network between medical disciplines and to promote further training for physicians in the aforementioned pathologies.

We call on the German government to simplify the bureaucratic processes for social security for those affected.

Rationale

In Germany alone, an estimated 300,000 people have developed myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) before the pandemic, including 40,000 children and adolescents. Recent studies show that approximately 10% of all Covid-19 infected individuals develop long or post-covid syndrome. In this context, about 40% of long-covid patients meet the diagnostic criteria for ME/CFS, a severe neuroimmunological disorder. [1,2] Underlying multisystemic inflammatory processes can occur after covid-19 infection as well as after vaccination, which is referred to as post-vaccine syndrome. [3-8]

What does this mean for the people affected?

Triathletes who suddenly find themselves in a wheelchair – medical students who can no longer solve basic math problems of first grade – affected who lie in darkened rooms because of over-sensitivity to any kind of stimuli with some even receiving liquid food because they can’t manage to lift their head off their pillow – thirteen-year-olds who can no longer sit upright, are carried to the toilet and have to stay away from school – people committing suicide due to the severity of the disease and the lack of therapies.

Promising drug

More than a year ago, four long-covid patients were treated with the drug BC 007 of the start-up company Berlin Cures GmbH in individual healing attempts at the University of Erlangen. With only a single intravenous administration of BC007 an enormous remission of the symptoms could be achieved, so that one could speak of a cure. A further treatment attempt of a ME/CFS patient who had been affected for years also showed efficacy and improved her condition enormously. [9,10] The effect of the drug BC007, in addition to binding the spike protein, lies mainly in neutralizing the autoantibodies against G protein-coupled receptors, which have been scientifically detected in more than 90% of the tested patients with Long Covid syndrome and are suspected to cause the symptoms. [11,12]

Common benefit of the drug for several disease pattern

Not only long-covid patients could benefit from BC007, but also ME/CFS and post-vaccine affected. This can be explained by the fact that these clinical pictures show great similarities. To validate the efficacy of BC 007, a large clinical trial is currently being intended by the company Berlin Cures GmbH. [13] However, due to missing financial and administrative support from the German government the approval of the drug may still drag on for many years. Time that those affected do not have! 

When compared internationally, Germany invests very little money in research into the disease patterns. Even the action plan presented by the German Society for ME/CFS and Long Covid Germany is not being implemented as called for. This leaves millions of severely ill people who are left alone with their suffering without effective therapies and medical care. This is not only tantamount to a failure to provide assistance, but also represents the quietest humanitarian disaster in the world!

Join us

The demands of the petition are in the interest of the entire population, since Long-Covid can affect anyone and represents an extreme burden for our health and social system. The loss of countless workers due to illness over a long period of time, or even forever, also causes considerable damage to the economy. If you have the same goals as we do, sign and spread this petition.

Do not look away!

This petition is represented by:

@nichtgenesen Instagram campaign (Long-/Post-Covid-Syndrome)

Faraz Fallahi (ME/CFS)

Felicia Binger (Post-Vaccine-Syndrome)

DJ..ME/CFS in a lot of countries is treated as "a mental issue" even when lots of indications point to auto-immune problems...

End of this part...

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 14 2022 at 11:40pm

DJ, 

The WHO claims the "CoViD pandemic is almost over"....(see also latest news)...DJ-No it is not! 

After a very major summer-wave of CoVid in many countries-some still in that wave (Japan a.o.) in lots of places CoViD cases are on the rise..a winterwave-with new variants-may be on its way...From MPX [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory hardly updated...if you ignore it it will go away-thinking ? to polio has to be linked to the ongoing CoViD pandemic...[url]https://www.worldometers.info/coronavirus/weekly-trends/[/url] or https://www.worldometers.info/coronavirus/weekly-trends/ 66 countries report an increase of cases, 34 see CoViD-deaths numbers going up...In Europe cases now -0,1%, deaths -5%...France, Poland see cases +36%, Germany cases +9% with very limited/poor testing & reporting...

The WHO was very wrong about aerosol spread of CoViD, The WHO did deny chronic CoViD [url]https://www.coronaheadsup.com/health/long-covid/long-covid-two-more-patients-treated-with-experimental-drug-bc-007-see-improvements-in-symptoms/[/url] or https://www.coronaheadsup.com/health/long-covid/long-covid-two-more-patients-treated-with-experimental-drug-bc-007-see-improvements-in-symptoms/ (good news from august 22) 

So [url]https://www.coronaheadsup.com/africa/world-health-organisation-the-end-is-nigh/[/url] or https://www.coronaheadsup.com/africa/world-health-organisation-the-end-is-nigh/ ;and blah, blah, blah….

DJ...Lots of countries try to get people motivated for yet another booster vaccine-with increase of news on "bad science" on vaccine safety...so the timing for "it is over" is bad...

[url]https://www.thailandmedical.news/news/breaking-are-certain-newer-sars-cov-2-variants-causing-a-rise-in-chronic-kidney-disease-and-kidney-failure-in-countries-like-singapore-and-thailand[/url] or https://www.thailandmedical.news/news/breaking-are-certain-newer-sars-cov-2-variants-causing-a-rise-in-chronic-kidney-disease-and-kidney-failure-in-countries-like-singapore-and-thailand DJ-My impression is most CoViD infections-must be in the billions by now!-are missed, never tested...Some variants may do more damage in the lungs, other more in bloodvessels, kidney, brain, liver...

[url]https://www.thailandmedical.news/news/what-is-really-happening-in-japan-covid-19-death-rates-are-spiraling-out-of-control-and-mortuaries-overflowing-but-authorities-are-painting-a-differen[/url] or https://www.thailandmedical.news/news/what-is-really-happening-in-japan-covid-19-death-rates-are-spiraling-out-of-control-and-mortuaries-overflowing-but-authorities-are-painting-a-differen with links to a.o. [url]https://www.asahi.com/ajw/articles/14711281[/url] or https://www.asahi.com/ajw/articles/14711281

In mid-August, a cold storage facility in a mortuary at a funeral home in Tokyo area was filled with nine bodies, the maximum capacity.

All the boards with the names of the deceased had the word “COVID,” as they were confirmed to have been infected with the novel coronavirus.

The mortuary, where bodies were kept before they are sent to the crematorium, was no longer able to house them since August.

Bodies approaching the cremation date were stored in a separate room of the funeral home with 10 kilograms of dry ice in their coffins.

Even so, there were more bodies that could not be accommodated. The funeral home was forced to leave those bodies in other funeral homes’ refrigerated storage facilities. 

and [url]https://cov-spectrum.org/explore/Japan/AllSamples/Past6M[/url] or https://cov-spectrum.org/explore/Japan/AllSamples/Past6M BA.2.75, BF.7 some BA.5 variants (all still named "Omicron" thank you WHO...) all increase..."Japan saving the economy/profits"....








BREAKING🔔 The 10th paper from G2P-Japan🇯🇵 is out at Cell  . #Omicron BA.5 variant is more contagious and pathogenic than BA.2 variant. Please RT. 1/8

link to [url]https://www.cell.com/cell/fulltext/S0092-8674(22)01190-4[/url] or https://www.cell.com/cell/fulltext/S0092-8674(22)01190-4 

DJ-It is impossible to limit a crisis when governments deny there is a crisis...we see it with climate collapse (hyper-soon) inflation, wars...pandemics get worse if you do not STOP THE SPREAD....

[url]https://www.thailandmedical.news/news/american-study-shows-that-twice-a-day-nasal-irrigation-with-saline-solution-helps-prevents-covid-19-disease-severity-and-mortality[/url] or https://www.thailandmedical.news/news/american-study-shows-that-twice-a-day-nasal-irrigation-with-saline-solution-helps-prevents-covid-19-disease-severity-and-mortality gurgle your throat try to get the virus out before it can get deeper inside the body...Even if it is not 100%, the lower the viral load-the better...

Masks, avoiding large crowds, social distance all work...but lots of people have been doing that for over 2,5 years...








U.S. COVID update: - New cases: 75,987 - Average: 72,313 (+7,010) - States reporting: 29/50 - In hospital: 33,179 (+141) - In ICU: 4,080 (+41) - New deaths: 306 - Average: 425 (+34)

End of part 1

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Part 2, history I love it !

[url]https://www.medrxiv.org/content/10.1101/2021.10.23.21265403v3[/url] or https://www.medrxiv.org/content/10.1101/2021.10.23.21265403v3 ;

Abstract

Past pandemic experience can affect health outcomes in future pandemics. 

This paper focuses on the last major influenza pandemic in 1968 (H3N2), which killed up to 100,000 people in the US. 

We find that places with high influenza mortality in 1968 experienced 1–4% lower COVID-19 death rates. 

Our identification strategy isolates variation in COVID-19 rates across people born before and after 1968. 

In places with high 1968 influenza incidence, older cohorts experience lower COVID-19 death rates relative to younger ones. 

The relationship holds using county and patient-level data, as well as in hospital and nursing home settings. 

Results do not appear to be driven by systemic or policy-related factors, instead suggesting an individual-level response to prior influenza pandemic exposure. The findings merit investigation into potential biological and immunological mechanisms that account for these differences—and their implications for future pandemic preparedness.

DJ [url]https://en.wikipedia.org/wiki/Hong_Kong_flu[/url] or https://en.wikipedia.org/wiki/Hong_Kong_flu ; The Hong Kong flu, also known as the 1968 flu pandemic, was a flu pandemic whose outbreak in 1968 and 1969 killed between one and four million people globally.[1][2][3][4][5] It is among the deadliest pandemics in history, and was caused by an H3N2 strain of the influenza A virus. The virus was descended from H2N2 (which caused the Asian flu pandemic in 1957–1958) through antigenic shift, a genetic process in which genes from multiple subtypes are reassorted to form a new virus.[6][7][8]

-

In 1968, many countries (e.g., the UK, Japan) did not immediately see outbreaks despite repeated introductions of the virus throughout August and September. Additionally, after September, there was little evidence of continued spread in new areas, despite similar importations of the virus into those areas. Epidemics did eventually develop during the winter months, but these were often mild (especially when compared to the US experience).[13] In some countries (such as the UK and Japan), it was not until the following winter of 1969–1970 that truly severe epidemics developed.[34]

Why there may be a link with the 1968 Hong Kong Flu and CoViD ? Do some flu-immunity offer better protection against CoViD ???

-








What is long COVID and what does it mean to live with it? Join us on September 15th for The Impact of Long COVID Symposium to learn more.  https://zcu.io/M9UN #LongCOVID #COVID19 #NotRecovered

DJ, I prefer to name it "chronic CoViD" but good there is more attention for it...[url]https://www.coronaheadsup.com/health/long-covid/nber-the-impacts-of-covid-19-illnesses-on-workers/[/url] or https://www.coronaheadsup.com/health/long-covid/nber-the-impacts-of-covid-19-illnesses-on-workers/ and [url]https://www.coronaheadsup.com/coronavirus/risk-of-developing-alzheimers-disease-increases-by-50-80-percent-in-older-adults-who-caught-covid-19/[/url] or https://www.coronaheadsup.com/coronavirus/risk-of-developing-alzheimers-disease-increases-by-50-80-percent-in-older-adults-who-caught-covid-19/ only underline the urgent need for much more study...

Maybe vaccines-so far-decreased people dying from CoViD-but if they end up with long term healthissues it still is bad !

-

Mandate Masks NY

@MandateMasksNY
 · 
Please sign our petition calling on NY @GovKathyHochul to reinstate the mask mandate on public transit in NY! #MaskTransit #MandateMasksNY #MandateMasks #COVIDIsNotOver #COVIDIsAirborne #HighRiskCOVID #HighRiskCOVID19 #StopTheSpread https://actionnetwork.org/petitions/urge-governor-hochul-to-reinstate-the-mask-mandate-on-public-transit/

DJ...why even masks in public transport ends up in discussions...

-


📍Rising again—for 2 straight weeks, #SARSCov2 levels rising in wastewater nationwide. The Northeast & Midwest are **above their respective Delta wave peaks**. Please #GetBoosted with new #BA5 bivalent shot. Come to US to get it free. HT  http://biobot.io/data

DJ, my impression is Europe may be the first "region" moving into a "winter CoViD crisis"....the economic/energy situation does not help...

End of part 2

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DJ, 

The US now also exporting for billions weapons to Taiwan-with the Shanghai Cooperation Organization meeting in Samarkand, Xi-Putin, Modi, Erdogan, Raisi have "a lot to discuss"...(latest news)

A study on adverse effects of new vaccines-compared to presumed risks of catching CoViD-could indicate vaccine risks might be higher for a lot of people....(general discussion)

So [url]https://www.thailandmedical.news/news/idiots-at-who-spreading-misinformation-again-and-claiming-covid-19-pandemic-end-is-near-and-claims-infections-rates-declining[/url] or https://www.thailandmedical.news/news/idiots-at-who-spreading-misinformation-again-and-claiming-covid-19-pandemic-end-is-near-and-claims-infections-rates-declining the title tells the story...I also did not see much twitter on the latest "fake news" the WHO produced...after missing/denying aerosol-spread of CoViD, chronic/long CoViD...this "pandemic almost over" claim fits in a list of this political organization serving economic goals NOT healthcare...

So "how close to over" is this pandemic ? [url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table even with low testing reporting still over 3 million new cases per week...global trend would be -13% for cases, deaths number -15%; last week 12,917 CoViD deaths were reported, last 7 days had 11,044 CoViD deaths reported...excess deaths all around the globe is "above the expected numbers"....

Europe cases-even with terrible bad reporting-now at +6%, deaths +2%...Africa cases would be -49%...however deaths would be +14%...

[url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time UK cases going up...in worldometers UK cases now +21%...(do they report cases once a week again...just stopped reporting cases for some weeks ?) France cases +46% 168,293 last 7 days...just under 25,000 new cases per day...NL will report new statistics on tuesdays and fridays...so today "cases -33%" is based on not reporting cases on a daily basis...

The pandemic is NOT over !!!

[url]https://nltimes.nl/2022/09/13/next-round-covid-vaccinations-netherlands-starts-monday[/url] or https://nltimes.nl/2022/09/13/next-round-covid-vaccinations-netherlands-starts-monday ;

The new round of vaccinations will be with the renewed Pfizer and Moderna vaccines, which the European Medicines Agency recently approved. In addition to the spike protein of the original coronavirus, these vaccines also contain the spike protein of the Omicron variant. “The renewed vaccines protect against more variants of the coronavirus,” the RIVM said. “The benefits of this repeat shot outweigh the possible side effects for everyone from the age of 12.”

DJ...so the "strategy" is to get immunity against CoViD via vaccinations and infections ? That "strategy" so far has been a disaster....resulting in more immunity evasion, less immunity protection against other diseases...

[url]https://www.thailandmedical.news/news/irrespective-of-severity-40-percent-of-post-covid-pneumonia-patients-still-have-impaired-lung-diffusion-and-22-percent-developed-lung-fibrosis-a-year-[/url] or https://www.thailandmedical.news/news/irrespective-of-severity-40-percent-of-post-covid-pneumonia-patients-still-have-impaired-lung-diffusion-and-22-percent-developed-lung-fibrosis-a-year- later...CoViD is NOT a joke ! Still politics/"experts" keep failing to get it under control...invest trillions in wars...NOT healthcare...

[url]https://www.coronaheadsup.com/coronavirus/lancet-covid-response-a-massive-global-failure-at-multiple-levels/[/url] or https://www.coronaheadsup.com/coronavirus/lancet-covid-response-a-massive-global-failure-at-multiple-levels/ ;

The Lancet Commission looking into the global SARS-CoV-2 pandemic response has levelled some withering criticism at the failure of governments and agencies to tackle the pandemic and uncover its origins.

Key quotes:

The proximal origin of SARS-CoV-2 remains unknown
No independent, transparent, and science-based investigation has been carried out regarding the bioengineering of SARS-like viruses that was underway before the outbreak of COVID-19
Independent researchers have not yet investigated the US laboratories engaged in the laboratory manipulation of SARS-CoV-like viruses
The US National Institutes of Health (NIH) has resisted disclosing details of the research on SARS-CoV-related viruses that it had been supporting

This staggering death toll is both a profound tragedy and a massive global failure at multiple levels

Too many governments have failed to adhere to basic norms of institutional rationality and transparency

Too many people – often influenced by misinformation – have disrespected and protested against basic public health precautions

The world’s major powers have failed to collaborate to control the pandemic

A lack of timely notification of the initial outbreak of COVID-19

Costly delays in acknowledging the crucial airborne exposure

The lack of coordination among countries regarding suppression strategies

The failure of governments to examine evidence and adopt best practices for controlling the pandemic

Shortfall of global funding for low-income and middle-income countries

Failure to ensure adequate protective gear, diagnostics, medicines, medical devices, and vaccines

The lack of timely, accurate, and systematic data on infections, deaths, viral variants

 

The Lancet Commission on lessons for the future from the COVID-19 pandemic

 

We haven’t found anything in the Lancet Commission’s report that we disagree with. The failures they illuminate have had catastrophic effects for hundreds of millions of people worldwide, and will continue to do so for generations to come.
There is no excuse for the failures either. There were plenty of early warnings of what was in store:

DJ....realistic number on global CoViD deaths most likely will at least be twice the "official" 6,5 million + CoViD tested/reported deaths...with millions more deaths-from lots of diuseases getting out of control because "we" failed to control CoViD on their way...

[url]https://www.who.int/news/item/15-09-2022-who-responds-to-the-lancet-covid-19-commission[/url] or https://www.who.int/news/item/15-09-2022-who-responds-to-the-lancet-covid-19-commission ...DJ-It is incorrect to put all of the blame at the WHO...national governments have their own responsibilities and simply failed to do even a decent job...

End of part 1

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Some twiiter in part 2, 

Double Individual Speculator

@x2IndSpeculator
 · 
Mind you, 15% excess mortality for 1Q 2022 is ABOVE the WHOLE YEAR of 2020 (14.7%). How is that even possible if #Omicron is mild, and the vast majority of people had by then already built up immunity vs. #SARS2 (through vaccination and/or infection)?
Show this thread

and

I can't wait for insurers to collect & publish Q2 & Q3 data. Much will be revealed & future will be clearer. If an immunity wall built through vaccination or infection (often both) is enough on its own & damage is not persistent or accumulating, deaths should go toward baseline.

DJ here in NL [url]https://nltimes.nl/2022/09/15/dutch-health-insurance-premium-will-rise-8-pct-next-year-eu137-per-month[/url] or https://nltimes.nl/2022/09/15/dutch-health-insurance-premium-will-rise-8-pct-next-year-eu137-per-month dental care, more then basic care will get unafordable for many in NL...at the end only further increasing health care costs...








Though some of this can be seen with severe flu, perhaps as part of a PICS effect (post-intensive care unit syndrome) in those who require hospitalization, flu viruses do not generally cause systemic (blood borne) infections in us. COVID-19 is a much more complex disease.

So get a better strategy !

And in the Netherlands they are advertising with the new Omicron vaccin. They are not telling the public that it is a BA.1 vaccin and that there is a BA.5 vaccin available that we are not getting! This wouldn't have been possible if BA.5 had gotten its own name.

How to get people trusting healthcare politics...

Joseph Butterfield

@Jo2Tony
 · 
So.. I can’t get a life insurance policy until 60 days after my positive COVID test. In case you thought COVID was no big deal.. apparently life insurance companies do.

and

Insurance companies are running the numbers. Risks after COVID seem higher than they are willing to take

DJ...Insurers may be good indicators...

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DJ, "limited" new news on the pandemic(s) so today I will focus-in latest news-more on the US-Russia war...








Replying to  and 
Amazing work by  and many others means that we aren't flying blind (we were on the lookout for a BA.2.75 lineage carrying mutations at 346 and 486). That, and  is remarkable at keeping on top of the variants.

DJ...YES it is important to keep an eye on new variants...however if governments remain in denial of any pandemic it could become frustrating...

[url]https://www.worldometers.info/coronavirus/weekly-trends/[/url] or https://www.worldometers.info/coronavirus/weekly-trends/ global reported cases -12%, CoViD deaths-as far as reported- -10%...Europe cases +7%, deaths +14%...all other regions now still reporting/claiming both cases and CoViD death-numbers are going down...Mongolia cases +233%...spread from Russia ? 

Botswana cases +193% also some other south African countries-now still in winter-report increase of cases...Iceland cases +113%...France +51%, Poland +35%, Belgium +31%, Germany +12%...NL +4%...67 countries now report an increase of cases...






Amanda Hu

@amandalhu
 · 
I’m just a random person on Twitter who doesn’t want kids to be part of experiments that purposely expose them to neurodegenerative pathogens to prove they shouldn’t be exposed to neurodegenerative pathogens ¯\_(ツ)_/¯

DJ, schools reopened, often ventilation not as good as needed-high energy costs...No masks...Several countries see CoViD on the rise in young children...


Accountability will only happen when we get together to insist on it.

For now the focus is on US made wars...

[url]https://twitter.com/mildanalyst/status/1570968613565386757/photo/1[/url] or https://twitter.com/mildanalyst/status/1570968613565386757/photo/1 


DJ BA.2.75.2 evades immunity from BA.5 ...there is NO immunity...with hundreds of "Omicron" subvariants around and vaccines getting less and less effective...

MPX [url]https://www.science.org/doi/10.1126/science.add3668[/url] or https://www.science.org/doi/10.1126/science.add3668 ;

Monkeypox: The consequences of neglecting a disease, anywhere

A disease anywhere can spread everywhere, if neglected

DJ...is there a "pandemic genocide strategy"????Or are politicians/"experts" this blind ? [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory no updates...denial...


NEW: Big Pharma began to pay fees to the F.D.A. 30 years ago with a 10% $ bump. Last year, the fees were 74% of the drug division budget. In turn, companies get faster decisions & more access to decision makers. Why some doctors say it's a problem:

DJ link [url]https://www.nytimes.com/2022/09/15/health/fda-drug-industry-fees.html[/url] or https://www.nytimes.com/2022/09/15/health/fda-drug-industry-fees.html maybe as a reminder...Big Pharma shareholders only are in it for profits...







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part 2...twitter






Antonio Caramia

@Antonio_Caramia
 · 
⚠️ #COVID19 deaths in England🏴󠁧󠁢󠁥󠁮󠁧󠁿 among children during the first 8 months of each year: 
👉0-4 2022 20 🔥 2021 5 2020 6 
👉5-9 2022 11 🔥 2021 5 2020 2 
👉10-14 yo 2022 6 2021 3 2020 6 
👉15-19 2022 28 🔥 2021  22 2020 12

and










2) If you can’t read the chart data - here they are written out. It’s incredibly striking. And don’t dare anyone try to say “but what’s their risk factors”— it doesn’t matter, kids are kids — kids should not die!

DJ...there is a wrong idea that "catching CoViD" would work like a vaccine against CoViD...it does NOT work that way-may bring major harm !


3) Why did this happen? Partly lack of acknowledgment that Omicron being more severe in kids, but also in UK vaccine rollout for kids under 11 were extremely slow (and now even stopped by crazy govts!). And govt misleading that kids immune led to more exposures of kids. So sad.

DJ..I would love to believe CoViD vaccines are "safe for all"...but even besides that point; why is working/school from home that impossible ? 









I agree—“most likely we will not be better prepared than we were in 2020” said 🇩🇪 health minister. ➡️“It’s only a matter of time until #climatechange makes more of these outbreaks become big enough that they become #pandemics”. Sobering.

Link;[url]https://www.hsph.harvard.edu/news/features/preparing-for-next-pandemic-g7-pact/[/url] or https://www.hsph.harvard.edu/news/features/preparing-for-next-pandemic-g7-pact/ DJ-Maybe we could be at the start of lots of pandemics already-if CoViD does destroy human immunity against diseases...

6) “We need a much better grounding of science in our daily policymaking,” he said. “Otherwise, there will be no way that we will master the challenges ahead.”

DJ, in the dark ages "religion" dominated...burning witches, blaming Jews for pandemics...anti-science...Now profit is anti-science...money rules the world with "neo-liberalism" weakening states, governments...bringing a balance out of balance...








IMPORTANT Finally we have an Omicron vaccine! A vax that many unvaccinated ppl have been waiting for But, there's a SERIOUS problem in US! You canNOT get the life-saving Omicron vax if you didnt get the original vax! This is unscientific policy

DJ...does the west has any pandemic strategy-other then big pharma profits-left ? 








Is the pandemic over? No. 🔹 Excess mortality has fallen but still exceeds THIRD global cause of death (below) 🔹Long COVID might itself be an emerging pandemic 🔹The evolutionary arc is incomplete 🔹The world is underprepared for what may come next

link [url]https://pandem-ic.com/global-severity-of-excess-mortality-section-by-income/[/url] or https://pandem-ic.com/global-severity-of-excess-mortality-section-by-income/ ;



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DJ, last posting a bit of a twitter collision....

I can not copy anything from the article [url]https://www.thailandmedical.news/news/covid-19-surge-starting-in-u-s-despite-coverups-29-states-report-a-total-of-98500-new-infections-and-832-deaths-in-last-24-hours[/url] or https://www.thailandmedical.news/news/covid-19-surge-starting-in-u-s-despite-coverups-29-states-report-a-total-of-98500-new-infections-and-832-deaths-in-last-24-hours but the basic story I take very serious;

Newer variants are getting even better in evading immunity-not only after recent infection but also the new vaccines, anti virals TMN claims (based on links in the article).

As a result the coming winterwave could become "very hard" with lots of people not out of a CoViD infection getting reinfected, developing more severe disease. Also mild cases may see more complications later on...resulting in higher excess deaths, even higher then we already see...

DJ-On top of that other diseases may be able to hit harder...a combination of CoViD and flu will often "not be a joke"...

[url]https://www.euromomo.eu/graphs-and-maps#excess-mortality[/url] or https://www.euromomo.eu/graphs-and-maps#excess-mortality (certainly if you also include last 3 prepandemic years, 2017 to 2019) may give a more realistic view...For all ages the last 10 weeks of the year did see excess death numbers go up high speed...We are now moving towards the last 15 weeks of 2022...

DJ [url]https://en.wikipedia.org/wiki/Exponential_growth[/url] or https://en.wikipedia.org/wiki/Exponential_growth

The growth of a bacterial colony is often used to illustrate it. One bacterium splits itself into two, each of which splits itself resulting in four, then eight, 16, 32, and so on. The amount of increase keeps increasing because it is proportional to the ever-increasing number of bacteria. Growth like this is observed in real-life activity or phenomena, such as the spread of virus infection, the growth of debt due to compound interest, and the spread of viral videos. In real cases, initial exponential growth often does not last forever, instead slowing down eventually due to upper limits caused by external factors and turning into logistic growth.

Terms like "exponential growth" are sometimes incorrectly interpreted as "rapid growth". Indeed, something that grows exponentially can in fact be growing slowly at first

for the present pandemic crisis-far from over !- yes-we did find ways to slow down growth...from lockdowns to vaccines...However this only did buy us time...the "diseases" did find new ways getting around our ways of stopping them...

Just a look at [url]https://outbreak.info/situation-reports[/url] or https://outbreak.info/situation-reports can give an impression of how CoViD-Omicron variants develop...The spread is a selection proces...

I think it is only realism to;

-relate MPX [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory simply not being updated by countries...to CoViD

-The spread of HPAI/"bird flu" often H5N1 as a potential next step..

-Measles killing hundreds allready in Africa may be yet another risk...

By NOT stopping the CoViD pandemic in time we may have opened the doors the a "healthcare hell"....

-A last note for this part 1 [url]https://en.wikipedia.org/wiki/African_swine_fever_virus#2018-2020_African_swine_fever_panzootic[/url] or https://en.wikipedia.org/wiki/African_swine_fever_virus#2018-2020_African_swine_fever_panzootic ...it would in my idea only make sense to relate a widespread disease being followed by another widespread disease with eachother...So what does African Swine Fever in pigs-pandemic-could have to do with the following CoViD pandemic ? 

Pigs may have had a co-infection with a corona virus ? That virus did not do that much-as far as is known-to the ASF infected pigs...Unless parts of the symptoms linked to AFS were in fact linked to CoViD but somehow were missed ? 

Historical theories[edit]

The appearance of ASF outside Africa at about the same time as the emergence of AIDS led to some interest in whether the two were related, and a report appeared in The Lancet supporting this in 1986.[90] However, the realization that the human immunodeficiency virus (HIV) causes AIDS discredited any potential connection with ASF.[citation needed]

So maybe linking ASF with the following CoViD pandemic would be just coincidence...? I do not believe in co-incidence...

End of part 1

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part 2, 

[url]https://www.worldometers.info/coronavirus/weekly-trends/[/url] or https://www.worldometers.info/coronavirus/weekly-trends/ has column 5-the middle column-cases per million in last 7 days...Taiwan had 11,600 cases per million last 7 days...only tiny Montserrat had more...Taiwan with 10 deaths per million at a #11...Greece reported 95 deaths per million...

[url]https://www.thailandmedical.news/news/breaking-taiwan-experiencing-anomalous-covid-19-surge-people-are-getting-re-infected-with-same-variants-ie-ba-2-3-and-ba-5-2-1-16-bf-16[/url] or https://www.thailandmedical.news/news/breaking-taiwan-experiencing-anomalous-covid-19-surge-people-are-getting-re-infected-with-same-variants-ie-ba-2-3-and-ba-5-2-1-16-bf-16 ...people getting reinfected-often with the same variant- (or did the variant hide and show up later ?)...

Hong Kong still at 7,725 cases per million last 7 days...Germany, France just above 2,700 per million getting reported...The main reason why cases per million for the UK, NL are low is simply lack of reporting...

-Ukraine [url]https://www.coronaheadsup.com/europe/ukraine/ukraine-nearly-5000-covid-cases-in-dnipropetrovsk-oblast-in-one-week/[/url] or https://www.coronaheadsup.com/europe/ukraine/ukraine-nearly-5000-covid-cases-in-dnipropetrovsk-oblast-in-one-week/ ;

A large outbreak of Covid-19 is being reported in Dnipropetrovsk Oblast, Ukraine.

During the week in Dnipropetrovsk Oblast, 4,492 people fell ill with acute respiratory viral infections, including suspected coronavirus.

This was reported by the regional laboratory center of the Ministry of Health of Ukraine.

It is noted that 4,492 people fell ill, of which 1,405 (31%) were children under the age of 17. Compared to the previous week, the incidence increased by 20%.

Full 1kr.ua news report (in Ukranian)

DJ, on top of all other problems...Ukraine is "only"reporting 237 new cases per million in the last 7 days...but the ongoing war does expain that...

[url]https://halturnerradioshow.com/index.php/en/news-page/world/first-snow-reaches-ukraine-europe-headed-into-cold-dark-deadly-winter[/url] or https://halturnerradioshow.com/index.php/en/news-page/world/first-snow-reaches-ukraine-europe-headed-into-cold-dark-deadly-winter.......This morning, September 18, 2022, in the far southwestern region of Ukraine, the first snow fell in the Carpathian Mountains. 

-








Sharing our investigation on the unprecedented convergent RBD evolution of BA.2.75 and BA.5 on sites including 346, 356, 444-446, 450, 460, 486, which have generated highly concerning variants such as BA.2.75.2, BR.1, BJ.1, and BQ.1.1. (1/n)

link [url]https://www.biorxiv.org/content/10.1101/2022.09.15.507787v1[/url] or https://www.biorxiv.org/content/10.1101/2022.09.15.507787v1 ;

Abstract

Continuous evolution of Omicron has led to numerous subvariants that exhibits growth advantage over BA.5. 


Such rapid and simultaneous emergence of variants with enormous advantages is unprecedented. 


Despite their rapidly divergent evolutionary courses, mutations on their receptor-binding domain (RBD) converge on several hotspots, including R346, R356, K444, L452, N460K and F486. 

The driving force and destination of such convergent evolution and its impact on humoral immunity established by vaccination and infection remain unclear. 


Here we demonstrate that these convergent mutations can cause striking evasion of convalescent plasma, including those from BA.5 breakthrough infection, and existing antibody drugs, including Evusheld and Bebtelovimab. 


BA.2.75.2 is the most evasive strain tested, and only BQ.1.1 could compare. 


To clarify the origin of the convergent evolution, we determined the escape mutation profiles and neutralization activity of monoclonal antibodies (mAbs) isolated from convalescents of BA.2 and BA.5 breakthrough infection. 


Importantly, due to humoral immune imprinting, BA.2 and especially BA.5 breakthrough infection caused significant reductions of neutralizing antibody epitope diversity and increased proportion of non-neutralizing mAbs, which in turn concentrated humoral immune pressure and promoted the convergent RBD evolution.


 Additionally, the precise convergent RBD mutations and evolution trends of BA.2.75/BA.5 subvariants could be inferred by integrating the neutralization-weighted DMS profiles of mAbs from various immune histories (3051 mAbs in total). 


Moreover, we demonstrated that as few as five additional convergent mutations based on BA.5 or BA.2.75 could completely evade most plasma samples, including those from BA.5 breakthrough infections, while remaining sufficient hACE2-binding affinity. 


These results suggest herd immunity established by natural infection could hardly stop RBD evolution, and vaccine boosters using BA.5 may not provide sufficiently broad protection. 


Broad-spectrum SARS-CoV-2 vaccines and NAb drugs development should be in high priority and the constructed convergent mutants could serve to examine their effectiveness in advance.

DJ...maybe one of the most shocking studies during this pandemic...but simply ignored...

End of part 2

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DJ, 

-In latest news/nuclear war my "view" on the present situation...Russia IS using Iran drones in Ukraine...claims of Chinese Army convoys entering Ukraine in support of Russia I think are very likely...need more confirmation. Russia-Iran-China RIC may have decided to go in the offensive on many frontlines...

It did not have to be this way...

Global war of course only worsening the pandemics. Wounded Ukraine military ending up in European -already overstretched-hospitals. Refugees with all kinds of diseases (here in NL polio in sewage linked to refugees) are a major concern...most refugees worldwide are linked to climate collapse (1/3 of Pakistan is flooded...).

-Pandemic news;

These two articles are linked; 

1 [url]https://www.coronaheadsup.com/health/long-covid/survey-reinfection-worsens-long-covid/[/url] or https://www.coronaheadsup.com/health/long-covid/survey-reinfection-worsens-long-covid/ ;

Reinfection worsens symptoms of Long COVID or triggers a recurrence of symptoms in people who have recovered.

Survey results were similar across adults and young people. As many as 89% of respondents first got Long COVID after their first infection, compared with 10% after the second infection, and just 1% after the third infection. Overwhelmingly, reinfection worsened the symptoms of Long COVID in most people who were still symptomatic.

In those who still had Long COVID at the time of reinfection, 80% saw their symptoms worsen vs. 10% who saw their Long COVID symptoms improve. Around 85% saw old symptoms return or new additional symptoms vs. 10% who had a resolution or improvement of symptoms.

In 60% of people who were in recovery or remission with Long COVID, reinfection caused a recurrence of Long COVID.

Survey: Effect of Covid Reinfection on People Living With Long Covid

and 2 [url]https://www.coronaheadsup.com/coronavirus/ba-2-75-2-exhibits-more-extreme-antibody-escape-than-any-variant-weve-seen-so-far/[/url] or https://www.coronaheadsup.com/coronavirus/ba-2-75-2-exhibits-more-extreme-antibody-escape-than-any-variant-weve-seen-so-far/ ;

Two preprints have been published over the last few days that give more details about the Omicron BA.2.75.2 sublineage. Both preprints show that BA.2.75.2 could represent a very serious threat to human health in the immediate future.

Ben Murrell, a researcher from the Karolinska Institute in Sweden, has published a long thread on Twitter that we are republishing below. The details are from the first preprint, titled “Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies”

-

In the second preprint, Yunlong Cao has given further details of his work that we first covered in this post. These details are from the second preprint, entitled “Imprinted SARS-CoV-2 humoral immunity induces converging Omicron RBD evolution”.

DJ [url]https://www.biorxiv.org/content/10.1101/2022.09.15.507787v1[/url] or https://www.biorxiv.org/content/10.1101/2022.09.15.507787v1 

In short - the two stories- newer variants are better in evading immunity, reinfection while reinfection does cause more long term damage....I discussed the-very serious !- article yesterday in my part 2. 

[url]https://www.thailandmedical.news/news/breaking-taiwan-experiencing-anomalous-covid-19-surge-people-are-getting-re-infected-with-same-variants-ie-ba-2-3-and-ba-5-2-1-16-bf-16[/url] or https://www.thailandmedical.news/news/breaking-taiwan-experiencing-anomalous-covid-19-surge-people-are-getting-re-infected-with-same-variants-ie-ba-2-3-and-ba-5-2-1-16-bf-16 fits in that "big picture"...and it is BAD !!!!

So, given the very bad outlook-very likely massive spread of CoViD resulting in less human immunity defenses-giving room for all kinds of other diseases (like MPX) to spread one would expect governments to protect public health...

[url]https://www.thailandmedical.news/news/biden-announces-that-the-covid-19-pandemic-is-over-study-shows-covid-19-increases-the-risk-of-alzheimer-in-older-adults-by-between-50-to-80-percent[/url] or https://www.thailandmedical.news/news/biden-announces-that-the-covid-19-pandemic-is-over-study-shows-covid-19-increases-the-risk-of-alzheimer-in-older-adults-by-between-50-to-80-percent DJ-Again this pandemic is the outcome of a total political faillure ! 

Both politics and (MIC owned) "media" continue to worsen the pandemic...

End of part 1

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part 2-twitter

John Ross 💉💉💉

@JohnRossMD
 · 
Astonishing graphic looking at race, socioeconomic status, and gender as predictors of US death rates from COVID in 2020. Blue-collar workers in "never remote" jobs had vastly disproportionate mortality. Paper by @bethpathek et al 👉https://ncbi.nlm.nih.gov/pmc/articles/PMC9102098/
Show this thread


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DJ [url]https://twitter.com/JohnRossMD/status/1545774040748625922/photo/1[/url] or https://twitter.com/JohnRossMD/status/1545774040748625922/photo/1 we are NOT all in the same boat !








Income, along with race and gender, is a shockingly robust predictor of COVID mortality in the US

more or less the same in lots of countries...Indonesia had a vaccine strategy trying to vaccinate those with high risk of spreading CoViD first (cab/bus drivers, healthcare, teachers...) maybe the strategy may make the difference ? 








Replying to 
Also BW.1 very similar (BA.5.6.2.1) with 444T and 460K designated tonite.

DJ...a bit cryptic, most likely yet another 9sub) variant even better in evading immunity...

One of the questions I have is what can/should I do ? I can get another booster-vaccine...I proberbly will take it...in the hope it offers some protection for me, may contribute to at least limiting the pandemic...In a recent NL poll 50% of adults that can get a new booster are willing to take one...Those that already did get booster(s) 67% is willing to take another one...

DJ, vaccines and vaccine-strategy are two different things in my opinion. Vaccines-I think-can statisticly be related with less (direct) CoViD deaths (within 28 days after a positive test). However excess deaths now in many places even higher then in 2020, 2021 may indicate "vaccines are far from perfect"...

Vaccine strategy has vaccines as part of a bigger plan...Vaccines may go to some groups first but on top of that there is also Non pharma Intervention; (legal right to) work/study from home, no mass events if possible, travel restrictions...STOP THE SPREAD !








Replying to 
Note that neither BQ nor BU are BA.2.75 descendants. BQ is a BA.5.3.1 descendant. BU is a BA.5.2 descendant. And BQ.1.1 is at least for now showing more growth advantage than BA.2.75.2 at https://cov-spectrum.org/collections/24 [as always sort by “CI (low)”]. Multiple lineages to watch.

DJ, claims that this pandemic is "almost"(???) over in my opinion border to insanity...








What we think is happening is that cryptic lineages are very long-term infections in people (often >1 year).  Perhaps GI infections.   The hosts are obviously mounting an immune response, but are not able to clear the infection.

DJ, long term infections may bring lots of mutations...oral/nasal tests in these people may be negative...missing the virus hidden in the body...In some cases more then one variant...








We see this in real data. For polyclonal serum to early #SARSCoV2, dominant epitope contained site E484 & subdominant epitope contained K417. Mutating E484 alone causes escape, mutating K417 alone causes no escape, & mutating both (as eventually virus did) causes lots of escape.

Winterwave is coming...

DJ-Again-exponential growth will not only result in lots of subvariants of CoViD but also less immunity against other diseases...

Three developments -mixing- may END humanity;

-1 Wars...what is wrong with diplomacy ?

-2 Pandemics...STOP THE SPREAD

-3 Climate collapse ...Puerto Rico did not recover from "Maria" 5 years ago...now they had "Fiona"...Pakistan is flooded-bringing lots of diseases and worsening the global foodcrises...

DJ-I live here and now...try to make the best of it...there are lots of things to enjoy ! I do worry about "the future", the next generations...Informing people may be a start !

End of part 2

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DJ, part 1,

-In general discussion I opened a topic on "this forum"...at best this is a forum on science. It has to provide room for different point of views, not for insults...I would welcome more-active-members. One of the reasons lots of people are not/no longer active may be due to the "climate" on this (and lots of other) forum(s)...

In general there seems to be less room for debate, exchange of views...I think that makes democracy weaker...Everybody is welcome to have their own opinion, nobody is "right" by definition...It is a view, an opinion...This is-again-not a scientific forum !

-I think one has to look at the background of pandemics. The Spanish Flu can be best understood by linking it to World War One...I do have a history background, not a medical one, and "history has room for lots of different views"...it is not an exact science.. So in latest news I plan to start something else...I have to think of a title; "Pandemic background" or something like that ? With discussion/info on economy, weather, wars...lots of things...

On the pandemic;

[url]https://www.coronaheadsup.com/health/ebola/research-long-ebola-symptoms-7-years-after-infection/[/url] or https://www.coronaheadsup.com/health/ebola/research-long-ebola-symptoms-7-years-after-infection/ ;

Even 5 years after acute Ebola infection, a majority of former patients continue to have symptoms and, for many, these continue to greatly impact their lives.

Symptoms of headache, fatigue, joint pain, muscle pain, hearing loss, visual loss, numbness of hands or feet were longitudinally assessed among participants in the Liberian Ebola Survivors Cohort study.

From June 2015 to June 2016, 326 survivors were enrolled a median of 389 days (range 51-614) from acute EVD. At baseline 75.2% reported at least one symptom; 85.8% were highly interfering with life. Over a median follow-up of 5.9 years, reporting of any symptom declined (odds ratio for each 90 days of follow-up = 0.96, 95% CI: 0.95,0.97; p < 0.0001) with all symptoms declining except for numbness of hands or feet. Rating of any symptom as highly interfering decreased over time. Among 311 with 5 years of follow-up, 52% (n = 161) reported a symptom and 29% (n = 47) of these as highly interfering with their lives.

Research: Post-Ebola Symptoms 7 Years after Infection: The natural history of Long Ebola

DJ [url]https://en.wikipedia.org/wiki/Chronic_fatigue_syndrome#Viral_and_other_infections[/url] or https://en.wikipedia.org/wiki/Chronic_fatigue_syndrome#Viral_and_other_infections ;

Post-viral fatigue syndrome (PVFS) or post-viral syndrome describes a type of chronic fatigue syndrome that occurs following a viral infection.[31] A recent review found Epstein-Barr virus (EBV) antibody activity to be higher in patients with CFS, and that a subset of patients with CFS were likely to have increased EBV activity compared to controls.[54] Viral infection is a significant risk factor for CFS, with one study finding 22% of people with EBV experience fatigue six months later, and 9% having strictly defined CFS.[55] A systematic review found that fatigue severity was the main predictor of prognosis in CFS, and did not identify psychological factors linked to prognosis.[56]

Another review found that risk factors for developing CFS after mononucleosis, dengue fever, or Q-fever included longer bed-rest during the illness, poorer pre-illness physical fitness, attributing symptoms to physical illness, belief that a long recovery time is needed, as well as pre-infection distress and fatigue.[57] The same review found biological factors such as CD4 and CD8 activation and liver inflammation are predictors of sub-acute fatigue but not CFS.[57] However, these findings are not generally accepted due to the use of the Oxford criteria in selecting patients. The CDC does not recognize attribution of symptoms as a risk factor.[6]

A study comparing diagnostic labels found that people labelled with ME had the worst prognosis, while those with PVFS had the best. Whether this is due to those with more severe or longer-lasting symptoms results in a label with the description of ME, or if being labelled with ME adversely causes a more severe or prolonged illness is unclear.[58]

So one may make a difference between "long CoViD" and "chronic CoViD" from that perspective. In (my view on) chronic cases the virus may still be hiding/active in the body..."L.C./Long CoViD" could be more related to damage the virus did do...In that view there may also be some "long chronic CoViD cases" ; with organ damage and still virus doing more damage...indications are a new CoViD infection may be worse...

-[url]https://www.coronaheadsup.com/health/hybrid-immunity/lancet-natural-immunity-associated-with-a-95-lower-risk-of-sars-cov-2-infection/[/url] or https://www.coronaheadsup.com/health/hybrid-immunity/lancet-natural-immunity-associated-with-a-95-lower-risk-of-sars-cov-2-infection/ ;

After the first 3 months, natural immunity was associated with a 95% lower risk of SARS-CoV-2 infection and an 87% lower risk of COVID-19 hospitalisation for up to 20 months.

The risk of SARS-CoV-2 reinfection and COVID-19 hospitalisation in individuals who have survived and recovered from a previous infection remained low for up to 20 months. Vaccination seemed to further decrease the risk of both outcomes for up to 9 months, although the differences in absolute numbers, especially in hospitalisations, were small.

Lancet article: Risk of SARS-CoV-2 reinfection and COVID-19 hospitalisation in individuals with natural and hybrid immunity: a retrospective, total population cohort study in Sweden

DJ, however as far as I understand the newest variants now showing up/detected may be much better in evading immunity...The article no doubt describing a situation from at least several months back...[url]https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00143-8/fulltext[/url] or https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00143-8/fulltext DJ Study is from march 31, 2022...

Methods

In this retrospective cohort study, we formed three cohorts using Swedish nationwide registers managed by the Public Health Agency of Sweden, the National Board of Health and Welfare, and Statistics Sweden. Cohort 1 included unvaccinated individuals with natural immunity matched pairwise on birth year and sex to unvaccinated individuals without natural immunity at baseline. Cohort 2 and cohort 3 included individuals vaccinated with one dose (one-dose hybrid immunity) or two doses (two-dose hybrid immunity) of a COVID-19 vaccine, respectively, after a previous infection, matched pairwise on birth year and sex to individuals with natural immunity at baseline. Outcomes of this study were documented SARS-CoV-2 infection from March 20, 2020, until Oct 4, 2021, and inpatient hospitalisation with COVID-19 as main diagnosis from March 30, 2020, until Sept 5, 2021.

So the info may be a bit "old"...maybe usefull to define a "baseline" however NOT usefull for the present (sub)variants...[url]https://www.coronaheadsup.com/coronavirus/ba-2-75-2-exhibits-more-extreme-antibody-escape-than-any-variant-weve-seen-so-far/[/url] or https://www.coronaheadsup.com/coronavirus/ba-2-75-2-exhibits-more-extreme-antibody-escape-than-any-variant-weve-seen-so-far/ and [url]https://www.coronaheadsup.com/science/variants/omicron/ba-2-75-2/ba-2-75-2-the-most-immune-evasive-strain-we-have-tested-so-far/[/url] or https://www.coronaheadsup.com/science/variants/omicron/ba-2-75-2/ba-2-75-2-the-most-immune-evasive-strain-we-have-tested-so-far/  in my opinion makes "protection after infection"claims unworkable, unrealistic...

-[url]https://www.coronaheadsup.com/science/origins/professor-jeffrey-sachs-is-pretty-convinced-covid-19-came-out-of-us-lab-biotechnology/[/url] or https://www.coronaheadsup.com/science/origins/professor-jeffrey-sachs-is-pretty-convinced-covid-19-came-out-of-us-lab-biotechnology/ ;

The chair of the Lancet Covid Commission, Professor Jeffrey Sachs, whose recent report into the global mismanagement of the SARS-CoV-2 pandemic we covered in this post, has used an online interview to explain his views on the origins of the SARS-CoV-2 coronavirus.

Professor Sachs says:

He is “pretty convinced [COVID-19] came out of US lab biotechnology”

That risky US-supported research may have led to millions of deaths

Thinks it is very possible that SARS-CoV-2 originated through dangerous virus research gone awry

There were several kinds of experiments of manipulation of the genes of dangerous viruses

He came to the conclusion that powerful actors were preventing a real investigation from taking place

There is extremely dangerous research taking place with little accountability

“It’s a blunder in my view of biotech, not an accident of a natural spillover”

He warns that there is dangerous virus research taking place without public oversight

He has come to the conclusion that there is extremely dangerous biotechnology research being kept from public view

He believes that there is clear proof that the NIH and many members of the scientific community have been impeding a serious investigation of the origins of COVID-19

“We don’t have definitive evidence of either hypothesis. But what we do have is definitive evidence that officialdom has tried to keep our eyes away from the lab creation hypothesis.”

Article: Why the Chair of the Lancet’s COVID-19 Commission Thinks The US Government Is Preventing a Real Investigation Into the Pandemic

DJ...As a "non-expert" I still think "it is natural"; bats have over 30 different corona virusses, SARS_1, MERS may have been early warnings...Is there a link to the African Swine Fever outbreak going global 2018-2020 ? Did pigs play a role in how "SARS-2" started ? 

There is a history of pandemics, climate change/collapse would further increase pandemic risks...so-in my opinion-"very limited room" for any lab-leak claims...(Peak Prosperity once claimed it had to be a lab-leak because of some basic changes very unlikely to be natural...again I am not a scientist/expert...). 

-Maybe on sources [url]https://www.coronaheadsup.com/[/url] or https://www.coronaheadsup.com/ does not provide info on who they are...Most of the time they do provide links for their stories/claims...DJ-Since a lot of their info makes sense to me (much more then "official" embedded media reuters, bbc, other military-industrial-complex owned media...). I could put (another) post on who owns the news...[url]https://en.wikipedia.org/wiki/Thomson_Reuters[/url] or https://en.wikipedia.org/wiki/Thomson_Reuters

Thomson Reuters Corporation (/ˈrɔɪtərz/ (listen) ROY-tərz) is a Canadian multinational media conglomerate.[4] The company was founded in Toronto, Ontario, Canada, where it is headquartered at the Bay Adelaide Centre.[5][6]

Thomson Reuters was created by the Thomson Corporation's purchase of the British company Reuters Group in April 2008[7] and is majority owned by The Woodbridge Company, a holding company for the Thomson family.[8]

DJ For if you had any illusions on western press...it is about profits, NOT about information...

End of part one..


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Part two, 

[url]https://www.thailandmedical.news/p/about-us[/url] or https://www.thailandmedical.news/p/about-us ;DJ, I can not copy from this site...once promoting Thailand medical industry, now trying also to inform/educate...DJ-My impression is there may be one person behind a lot of the articles...I do not always agree with the words being used (more immunity evasion as "more fun") but most of the times it has links...makes sense for me-forming my opinion...

[url]https://www.thailandmedical.news/news/researcher-conducting-wastewater-surveillance-of-sars-cov-2-variants-predicts-that-the-next-concerning-variants-will-be-the-bu-and-bq-variants[/url] or https://www.thailandmedical.news/news/researcher-conducting-wastewater-surveillance-of-sars-cov-2-variants-predicts-that-the-next-concerning-variants-will-be-the-bu-and-bq-variants 

DJ TMN has a very outspoken opinion on this pandemic NOT being over. The present lack of strategies will result in newer variants doing even worse...a link [url]https://twitter.com/SolidEvidence/status/1571579049738117122[/url] or https://twitter.com/SolidEvidence/status/1571579049738117122 ;


There you have it.  BQ and BU.  I don't know if they will cause a spike in total cases, but barring something completely new appearing, I predict that they will be the dominant VOCs in the coming months.


and from that twitterlink;

Addendum.  It seems a few other lineages have hit very similar 'jackpot' combinations very recently. In addition to BU and BQ: BW.1 (BA.5.6 derivative) BS.1 (BA.2.3 derivative)   BR.2 (BA.2.75 derivative) other undesignated They all have N460K, L452R + other changes.

DJ Also a [url]https://github.com/cov-lineages/pango-designation/issues/1065[/url] or https://github.com/cov-lineages/pango-designation/issues/1065 link...discussing what the detected mutations mean...A lot of good info will show up later in "main stream media" as far as they are not claiming "pandemic=over"again and again...

The article is full of science-links...I have given up on "new variants" [url]https://outbreak.info/situation-reports[/url] or https://outbreak.info/situation-reports has lots of them...(Omicron itself close to 600 subvariants...critics claim naming them all "Omicron" is simply hiding the fact they are different "VoC"s Variants of Concern...). 

Maybe basic point is several variants have mutations that will bring more spread...

DJ-To keep it workable for me I use two basic ideas;

-1 Disease triangle; Disease-Transport-Host

-2 Exponential growth

If a disease does not spread (genetic origen) the R0-reproduction number is 0...simple...An infectious disease needs to spread, at least at the start have an R0 of 1+ ..if the R0 is lower then 1 the spread is decreasing...In other words 100 people would infect less then a 100 other people...If the R0 is 10 one would see 100 people infecting a 1,000 other people...

As far as I understand the R0 early 2020 in China for the variant(s) spreading there at that time may have been close to 6...Here in NL the highest R0 may have been around 2...

However the fear is new variants could have a R0 much higher then we do see so far...[url]https://en.wikipedia.org/wiki/Measles[/url] or https://en.wikipedia.org/wiki/Measles ;

Measles is an airborne disease which spreads easily from one person to the next through the coughs and sneezes of infected people.[7] It may also be spread through direct contact with mouth or nasal secretions.[14] It is extremely contagious: nine out of ten people who are not immune and share living space with an infected person will be infected.[5] Furthermore, measles's reproductive number estimates vary beyond the frequently cited range of 12 to 18.[15] The NIH quote this 2017 paper saying: "[a] review in 2017 identified feasible measles R0 values of 3.7–203.3".[16] People are infectious to others from four days before to four days after the start of the rash.[5] While often regarded as a childhood illness, it can affect people of any age.[17] Most people do not get the disease more than once.[7] Testing for the measles virus in suspected cases is important for public health efforts.[5] Measles is not known to occur in other animals.[14]

DJ..Comparing CoViD (Corona Viral Disease) with measles; lots of animals may be able to catch CoViD however spreading it further may be limited often...so far... (Minks, US deer a.o. are exceptions..). Another aspect of CoViD may be weakening general immunity...It is likely there are billions of CoViD cases...both in humans and at least non-human infections run in the tens-of-millions (with millions of minks getting killed in DK, NL etc. to limit the risk). 

[url]https://www.thailandmedical.news/news/american-study-discovers-that-sars-cov-2-infections-impairs-antiviral-innate-immune-gene-expression-in-the-placenta[/url] or https://www.thailandmedical.news/news/american-study-discovers-that-sars-cov-2-infections-impairs-antiviral-innate-immune-gene-expression-in-the-placenta link to [url]https://www.ajog.org/article/S0002-9378(22)00747-5/fulltext[/url] or https://www.ajog.org/article/S0002-9378(22)00747-5/fulltext ;

Conclusion

A maternal SARS-CoV-2 infection was associated with an impaired placental innate immune response in chorionic villous tissues and chorioamniotic membranes that was not correlated with gestational age at COVID-19 diagnosis, timer interval from COVID-19 diagnosis to delivery, maternal obesity, disease severity or placental pathology.

DJ-Is this "bad"? YES This is terrible ! [url]https://en.wikipedia.org/wiki/Innate_immune_system[/url] or https://en.wikipedia.org/wiki/Innate_immune_system You are born with a basic immune system...If CoViD infection of the mother does damage that basic immunity system in the baby the baby may have immunity problems...Also pregnant women could be at more risk...

More studies are needed...

HOWEVER !!! IF !!!! CoViD-19 does massive damage to immunity are we heading towards billions of cases of [url]https://en.wikipedia.org/wiki/HIV[/url] or https://en.wikipedia.org/wiki/HIV ????

-Another point is how bad is CoViD [url]https://www.thailandmedical.news/news/breaking-report-claims-that-during-covid-19-pandemic-in-singapore,-up-to-60-percent-of-excess-deaths-was-due-to-sars-cov-2[/url] or https://www.thailandmedical.news/news/breaking-report-claims-that-during-covid-19-pandemic-in-singapore,-up-to-60-percent-of-excess-deaths-was-due-to-sars-cov-2 ...DJ by limiting the definition to "dying from CoViD within 28 days after a positive test" (I do not know if that is the international norm...) lots of excess deaths are not labelled as CoViD deaths...

[url]https://www.worldometers.info/coronavirus/#main_table[/url] or https://www.worldometers.info/coronavirus/#main_table has a global of almost 618 million tested/reported CoViD cases with 6,532,065 "reported" CoViD deaths...Some claim this means a "case fatality ratio" of just over 1%...

However the real number of CoViD cases in humans may be over 2 billion...a realistic number of people dying as a result from a CoViD infection would at least be double the official number-so over 13 million...(If one would go for 2 billion cases then 20 million deaths would be a "CFR" of 1%...). A bad flu may kill up to 0,6% of cases 

[url]https://en.wikipedia.org/wiki/Influenza[/url] or https://en.wikipedia.org/wiki/Influenza ; In a typical year, 5–15% of the population contracts influenza. There are 3–5 million severe cases annually, with up to 650,000 respiratory-related deaths globally each year. Deaths most commonly occur in high-risk groups, including young children, the elderly, and people with chronic health conditions. In temperate regions of the world, the number of influenza cases peaks during winter, whereas in the tropics influenza can occur year-round. Since the late 1800s, large outbreaks of novel influenza strains that spread globally, called pandemics, have occurred every 10–50 years. Five flu pandemics have occurred since 1900: the Spanish flu in 1918–1920, which was the most severe flu pandemic, the Asian flu in 1957, the Hong Kong flu in 1968, the Russian flu in 1977, and the swine flu pandemic in 2009.

DJ...So 5-15% of what population ? The almost 8 billion global population ? Say 10% to make it easy...800 million flu cases...then 1% would mean 8 million deaths...I believe the "norm" for flu-deaths per year is between 400,000 and 600,000...

Point is even if you go for 650,000 flu deaths per year CoViD killed 10x that number in reported, confirmed cases in less then 3 years...On top of that there are "pandemic deaths" not dying from CoViD but because the pandemic did result in not getting treatment in time for other illnesses..[url]https://www.euromomo.eu/graphs-and-maps#excess-mortality[/url] or https://www.euromomo.eu/graphs-and-maps#excess-mortality is one of the statistics on excess mortality (in Europe/Israel). 

DJ-So indications are new variants may have mutations resulting in more spread (R0 going up). Also CoViD results in weaker immunity. 

One of the major background stories is "bird flu" at record-all year round-level in many places...with lots of them [url]https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1[/url] or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1 ...if (human) immunity is getting weaker we may see an increase of (lots of) other infectious diseases...More agressive types of flu could be one of them...but also [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory (no longer updated...) very likely may have a CoViD link...

DJ-Again I am NOT an expert ! Trying to make up my mind on what to do...

-So far i did take four vaccinations (2x moderna (booster)/2x pfizer) and I can get another booster soon...

-I limit contacts/mass events...

-I try to get the best info available (and that does NOT come from the government/CDC-like experts...allthough [url]https://coronadashboard.government.nl/[/url] or https://coronadashboard.government.nl/ has lots of good info)

End of part 2...maybe I find time for a part 3...

We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein
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part 3, 

What NL info is there on [url]https://coronadashboard.government.nl/[/url] or https://coronadashboard.government.nl/

Positive tests went up +6%...waste water/sewage +4,4%, increase of BA.2.75 variants in NL...

[url]https://coronadashboard.government.nl/landelijk/reproductiegetal[/url] or https://coronadashboard.government.nl/landelijk/reproductiegetal NL R0 now at 1,07...an increase of 0,03...(per august 30-the R0 is calculated on data from 2 weeks ago). 

[url]https://coronadashboard.government.nl/landelijk/varianten[/url] or https://coronadashboard.government.nl/landelijk/varianten has more on the variants in NL; 

last 30 days NL variants were (22-28 august) 

93,1% BA.5

5,9% BA.4

0,5% BA.2.75

DJ-All three variants have loads of subvariants...moving a little further;29 august till september 4

92,9% BA.5

5,6% BA.4

0,7% BA.2.75

0,4% BA.2

15-21 august only had 0,3% BA.2.75..so it more the doubled while BA.5/BA.4 sequences went down...Also the R0 going up fits in with studies indicating BA.2.75 is more infectious...

[url]https://coronadashboard.government.nl/landelijk/ziekenhuis-opnames[/url] or https://coronadashboard.government.nl/landelijk/ziekenhuis-opnames 

NL has 42 people getting into hospital for CoViD each day at the moment, with 403 total (-3 since week before) CoViD cases in hospital...

[url]https://coronadashboard.government.nl/landelijk/geldende-adviezen[/url] or https://coronadashboard.government.nl/landelijk/geldende-adviezen advice; wash your hands...DJ-Not a bad advice in itself...but most of the spread is NOT via contact but aerosol...we do not even have masks in public transport...

[url]https://coronadashboard.government.nl/landelijk/verdenkingen-huisartsen[/url] or https://coronadashboard.government.nl/landelijk/verdenkingen-huisartsen GP data...

Other NL info-not new in fact; [url]https://nltimes.nl/2022/09/19/psychiatric-patients-may-extra-vulnerable-covid-19-study[/url] or https://nltimes.nl/2022/09/19/psychiatric-patients-may-extra-vulnerable-covid-19-study ;

The coronavirus-related mortality rate is much higher among psychiatric patients than among the general population, researchers from Nijmegen and Utrecht found after analyzing a special register.

The register contains information about 143 psychiatric patients who got Covid-19. Eighteen of them died, Trouw reports. That amounts to a mortality rate of 12 percent, while the RIVM estimated the average percentage of Covid-19 patients who died in 2020 at 1 to 6 percent.


“We expected the death rate to be higher than average, but not twice as high,” researcher Daphne Everaerd, a psychiatrist affiliated with Radboudumc in Nijmegen, said to the newspaper.

Most psychiatric patients live at home and not in care institutions, where the Covid-19 mortality rate is also higher. The researchers could not say whether vaccination coverage played a role in the higher mortality rate.


The researchers analyzed a Case Register opened by the Dutch Psychiatric Association (NVvP) in April 2020 due to early concerns that psychiatric patients were more likely to become seriously ill or die from the coronavirus. It was already known that psychiatric patients are more susceptible to infections because of poor physical conditions. The register is not a complete picture of all coronavirus infections among psychiatric patients. Patients with severe illnesses, like psychotic disorders, are overrepresented in the Case Register, while patients with addictions and intellectual disabilities are underrepresented.

The researchers found that psychiatric patients who had neuropsychiatric symptoms during the coronavirus infection, such as delirium and anxiety, often had a more severe course of the disease. The risk of death also seems to be higher in that group. Coronavirus patients with no previous psychiatric complaints who got neuropsychiatric symptoms during Covid-19 also became sicker, but their death rate was significantly lower.

According to Violet van Dee, a researcher at UMC Utrecht, these symptoms can serve as an “early signal for a more severe course” of Covid-19. “The problem with people with a psychiatric illness is that the new symptoms are more difficult to recognize. Perhaps they are suppressed by medicines like antipsychotics. It is important to be aware of this,” she said to Trouw.

The researchers stressed that their findings are not hard conclusions but indications that are in line with international studies. The results of their analysis were published in the Tijdschrift voor Psychiatrie on Monday.

DJ, Also in NL lower income groups, ehtnic groups are over represented...

A look at [url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table has NL cases -30%, deaths -25% however since NL now only twice a week reports it latest numbers these statistics simply give the wrong info...

[url]https://www.worldometers.info/coronavirus/#main_table[/url] or https://www.worldometers.info/coronavirus/#main_table NL population 17,2 million...number of confirmed tested CoViD cases in NL 8,4 million...The over 22,000 CoViD deaths is excluding the deaths in NL carecenters...they ended up in statistics as deaths from old age...other statistics put NL CoViD deaths over 40,000...Looking at cases per million-translation is 48,8% of the NL population tested positive...The NL 1,315 deaths per million is ignoring the care center deaths...(A more realistic number around 2,000 deaths per million? ). 

Comparing NL numbers with Germany there 39% of the population tested positive...1,777 deaths per million.

Belgium 38,7% of the population tested positive, 2,796 deaths per million...Belgium did include all their CoViD deaths (maybe even those dying after 4 weeks/test+)

Comparing countries is "complicated" when definitions differ...Belgium is much more active in testing then Germany...NL even less active then Germany looking at tests per million...

NL may be doing "reasonably high" in vaccinations...that number is not in these statistics...[url]https://coronadashboard.government.nl/landelijk/vaccinaties[/url] or https://coronadashboard.government.nl/landelijk/vaccinaties 82,8% of the NL population at least did get two vaccines...63,9% also a booster-vaccine...

[url]https://coronadashboard.government.nl/gemeente/GM0363/positief-geteste-mensen[/url] or https://coronadashboard.government.nl/gemeente/GM0363/positief-geteste-mensen Amsterdam did see 6,4 positive tests per 100,000 of the population in the last 7 days...Arnhem 5,5...Leiden-lots of students-had 8 per 100,000...there are regional differences...

Proberbly lots more info...[url]https://twitter.com/josetteschoenma[/url] or https://twitter.com/josetteschoenma a.o. also following NL situation...just as an example...

Most countries have similar government info-sites...it can give a lot of info on trends...One may compare it with other sites-you do not need a university degree to compare basic numbers !

End of part 3


We cannot solve our problems with the same thinking we used when we created them.
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DJ, 

In latest news-nuclear war on how referenda in 4 Ukraine regions on joining Russia may end the "Special Military Operation" (in support of Donetsk, Luhansk) and change into war if there is further Ukraine action against what Russia then will see as (former Ukraine) part of Russia...

What is wrong with diplomacy !

-Pandemic(s)

[url]https://www.coronaheadsup.com/science/variants/omicron/ba-2-75/ecdc-designates-ba-2-75-as-a-variant-of-concern/[/url] or https://www.coronaheadsup.com/science/variants/omicron/ba-2-75/ecdc-designates-ba-2-75-as-a-variant-of-concern/ ;

Marco Cavaleri, Head of Health Threats and Vaccines Strategy at the European Medicines Agency has revealed today that the Omicron variant BA.2.75 is now being monitored as a Variant of Concern (VOC) by the ECDC.

The ECDC webpage dedicated to tracking SARS-CoV-2 variants hasn’t yet been updated – BA.2.75 is still listed as a Variant of Interest (VOI) there, but designating BA.2.75 as a VOC is a big step up in the threat profile for this particular variant.

DJ [url]https://outbreak.info/situation-reports?pango=BA.2.75[/url] or https://outbreak.info/situation-reports?pango=BA.2.75 provides info on last 60 days...on that basis BA.2.75 is under 0,5% of detected sequences...So far 47 countries reported BA.2.75 cases...most in India-region...Austria is at #4...[url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table Austria cases +26% (however New Zealand is at #5...cases there -30%...but it may be poor testing/reporting...). 

[url]https://www.coronaheadsup.com/coronavirus/ba-2-75-2-exhibits-more-extreme-antibody-escape-than-any-variant-weve-seen-so-far/[/url] or https://www.coronaheadsup.com/coronavirus/ba-2-75-2-exhibits-more-extreme-antibody-escape-than-any-variant-weve-seen-so-far/ and other info on (a.o.) BA.2.75 variants is alarming...A main reason we do not yet see an explosion of global number of cases is lack of testing/reporting...[url]https://www.thailandmedical.news/news/great-news-the-official-arrival-of-fall-in-the-northern-hemisphere-is-being-commemorated-by-the-sars-cov-2-virus-with-a-rise-of-cases-in-various-count[/url] or https://www.thailandmedical.news/news/great-news-the-official-arrival-of-fall-in-the-northern-hemisphere-is-being-commemorated-by-the-sars-cov-2-virus-with-a-rise-of-cases-in-various-count 

-[url]https://www.coronaheadsup.com/asia/north-korea/north-korea-masks-mandated-for-the-winter-to-prevent-covid-19/[/url] or https://www.coronaheadsup.com/asia/north-korea/north-korea-masks-mandated-for-the-winter-to-prevent-covid-19/ ;

North Korea has announced a facemask mandate for the entire nation to begin in October and to last all winter. 

North Korea suffered a severe wave of Covid-19 in May 2022. Due to a lack of testing facilities at that time, the disease was often referred to as ‘malignant fever’.

The North Korean press release that we have translated and republished below is the first time we have seen Covid-19 referred to in an official North Korean document.

In the autumn season, the temperature is dropping in most areas of our country, including the northern alpine region, and the temperature difference between day and night is getting bigger.

The World Health Organization and health professional organizations in various countries have already expressed serious concerns about the consequences of complications caused by viruses due to the simultaneous flow of “COVID-19” and the common cold in the fall and winter of this year.

Our quarantine and health experts also emphasized the dangers of the common cold spreading in neighboring countries and regions in recent times, and recommending that all residents wear masks to protect their health from October when the weather starts to get cold.

While closely monitoring the nationwide quarantine situation, the National Emergency Response Command is continuously raising the overall social quarantine atmosphere by promptly delivering instructions detailing treatment and prevention measures related to the flu and materials following the change in the global quarantine situation.

In line with the demands of the heightened normal quarantine system, we are maintaining a general awareness and awareness of quarantine, while anticipatingly establishing epidemic prevention measures in response to seasonal changes.

We are strengthening our propaganda project so that everyone is familiar with health management methods and common sense that can prevent respiratory diseases and consciously observes hygiene and quarantine regulations.

A project that scientifically and technologically refines the examination systems and methods that can detect various diseases accompanied by fever at the relevant medical research institutes in a timely manner, and continuously explores and introduces reasonable methods to promote winter health management in accordance with realistic conditions. are also promoting

Quarantine units and health institutions at each level maintain a high degree of responsibility in the quarantine situation management and treatment prevention projects of their own areas and units, and in order to cleanly eradicate various pathogenic microorganisms, including Dolimb virus, in business spaces, work spaces, and living spaces. The disinfection of the spaces is being carried out more thoroughly.

KCNA.kp press release (in Korean)

DJ...Mask are a cheap and easy way to limit (aerosol) spread of infectious diseases...No doubt NK has been hit hard with CoViD...but very likely other infectious disease-on top of that-are very unwelcome. As far as I ubderstand Russia (in exchange for weapons ?), China (in exchange for coal) may have provided limited vaccines..(party members first ?)...So Non Pharma Intervention may be the main NK strategy...

-[url]https://www.coronaheadsup.com/health/ebola/uganda-ebola-outbreak-confirmed-8-suspected-cases/[/url] or https://www.coronaheadsup.com/health/ebola/uganda-ebola-outbreak-confirmed-8-suspected-cases/ ;

The World Health Organisation has confirmed an outbreak of Ebola in Uganda, the first time the disease has been recorded in the country for ten years.  The outbreak comes just weeks after the Democratic Republic of the Congo also declared an Ebola outbreak.

The health authorities in Uganda today declared an outbreak of Ebola after a case of the Sudan ebolavirus was confirmed in Mubende district in the central part of the country.

The Uganda Virus Research Institute confirmed the case after testing a sample taken from a 24-year-old male. This follows an investigation by the National Rapid Response team of six suspicious deaths that have occurred in the district this month. There are currently eight suspected cases who are receiving care in a health facility.

-

There have been seven previous outbreaks of the Sudan ebolavirus, with four occurring in Uganda and three in Sudan. Uganda last reported an outbreak of Sudan ebolavirus in 2012. In 2019, the country experienced an outbreak of Zaire ebolavirus. The virus was imported from neighbouring Democratic Republic of the Congo which was battling a large epidemic in its north-eastern region.

DJ...Is Ebola increasing ? Is there a CoViD-relation ? Very likely limited data...More healthcare surveilance may result in finding more infectious diseases..(may also work that way for Polio, measles etc...) so if you "look better you may see more"...

Uganda, DRC etc. may not be able to provide much info of the health background of Ebola cases...Did they have had CoViD, resulting in less immunity ? Is the Ebola-virus behaving differently-could we see a "Monkeypox/MPX scenario" for Ebola ???? After Ebola infection people may have long term-years- health issues...

-The "Big Picture" in my opinion is massive-billions of cases-spread of CoViD may endanger human defenses against lots of diseases...from cancers to flu...Excess deaths numbers around the globe may give some indications for that...

Again "STOP THE SPREAD" in my idea is urgently needed to stop pandemics becoming a major risk for human survival...but "who cares"? 

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
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part 2, NL situation; 

[url]https://nltimes.nl/2022/09/19/half-netherlands-wont-get-repeat-covid-vaccination[/url] or https://nltimes.nl/2022/09/19/half-netherlands-wont-get-repeat-covid-vaccination ;

About half of adult Netherlands residents see no need to get another jab against the coronavirus, NOS reports based on a survey by I&O Research. The new round of coronavirus vaccinations, using the renewed vaccines by Pfizer and Moderna to better protect against the Omicron variant, starts in the Netherlands today.

The researchers expect that the adults who didn’t get the booster shot (36.1 percent of the adult Dutch population) will also not get the repeat shot. Of those who did get the booster, 17 percent said they wouldn’t or probably wouldn’t get the repeat shot. 67 percent of people who got the booster will also get the repeat shot.


Age plays a clear role in the willingness to participate in this round of vaccinations. Young people between the ages of 18 to 34 are most reluctant, with 32 percent saying they won’t or probably won’t get the repeat shot. In the age group just above that, up to 49 years, 22 percent won’t go for the jab.

According to Marjolein van Egmond, professor of immunology at Amsterdam UMC, people often show up less for a second or third injection. “You often hear people say: I think I’ve had enough. But it doesn’t work that way in biology. The virus is still there, the immune system is decreasing, and a repeat shot is to refresh that defense,” she said to NOS. “In the elderly and those in poor health, it could be the difference between going to the hospital or not.”


Van Egmond called it “very likely” that there will be a revival of the coronavirus this autumn. “In the autumn, when it gets colder, people move closer together, and the virus spreads more easily

DJ...there is a government (tax funded) vaccination program. So people in NL do not have to pay for CoViD vaccines...Groups at increased risk/60+ also can get a (tax funded) flu vaccine next month...For young children there are also vaccinations free-of-charge, other specific groups at risk most often can get vaccinated without payment...

[url]https://nltimes.nl/2022/09/20/nl-residents-can-expect-big-increase-health-insurance-premiums-menzis-director[/url] or https://nltimes.nl/2022/09/20/nl-residents-can-expect-big-increase-health-insurance-premiums-menzis-director ;

Netherlands residents must prepare themselves for a significant increase in health insurance premiums, Menzis CEO and former PvdA leader Wouter Bos said on NPO Radio 1 program Geld of je Leven.

Sources leaked that the Cabinet will announce a 10 to 12 euros per month increase in health insurance premiums on Budget Day today. “People should indeed prepare for that amount,” Bos said. “Insurers can still choose whether they go above or below that. But it is obvious that the premium will go up.”


He called the premium increase inevitable, even in this time of bills piling up. “Ninety percent of this increase can be explained by the fact that people in healthcare want to earn more. I think that’s justifiable - they should also be able to cope with the higher prices. But if wages and prices rise sharply, this immediately translates into what we have to pay for healthcare.”

Health insurers can’t automatically use their own equity to reduce the premium because regulator DNB requires them to maintain a buffer for bad times, Bos explained. “We believe the buffer should be a little lower, but it is not up to us.”


He stressed that Menzis is very aware of the purchasing power crisis. “We believe that as a health insurance company, we have a broad responsibility. Preventing stress and debt problems is part of that. We work with municipalities and organizations that focus on debt problems. The biggest problem is if you find out too late that people have difficulties. We think we have that in order now.

DJ, Here in NL everybody is expected to take basic healthinsurance...There are people without legal status-sometimes living in NL for years-however unable to get basic healthinsurance...There is very limited, very basic medical care for that group (may be thousends...often in larger cities/poor area's). In a "bizarre market strategy" insurers try to sell health insurance...with lots of money ending up in advertising/sponsoring...

NL has a lot of oil and gas (a.o. North Sea) but the same "market dogma" means explorers selling the oil/gas to European/other buyers that then sell it to energy companies...Also supposed to be "market based" but in fact often companies (like [url]https://en.wikipedia.org/wiki/Vattenfall[/url] or https://en.wikipedia.org/wiki/Vattenfall ) that are still owned (100% of the shares) by some government...

There is a lot of criticism on "European market strategy"; consumers end up paying extra for profits, managers, advertising etc..."Competition" did not bring lower prices...Energy, healthcare, water all once-in many countries-was done by (local) government(s)...Privatization often made matters more complex and NOT cheaper...

[url]https://nltimes.nl/2022/09/21/consumer-confidence-new-low[/url] or https://nltimes.nl/2022/09/21/consumer-confidence-new-low ;

The mood among consumers deteriorated further in September. Consumer confidence dropped from -54 in August to -59 this month, breaking the record low for the fifth time this year. “Consumers have never been so negative about the economy and their financial situation,” Statistics Netherlands (CBS) said on Wednesday.

At -59, consumer confidence in September was a massive 50 points below the -9 average for the past two decades.


Consumers were even more pessimistic about the economy, with the economic climate sub-indicator falling from -74 in August to -79 in September. “Never before since the start of the measurement in 1986 were consumers so pessimistic about the economy.” Their willingness to buy was also historically low, dropping from -41 to -46.

Netherlands residents were more pessimistic than ever about their financial situation in both the past year and the coming 12 months. This month, 46 percent called it unlikely to very unlikely that they would be able to set aside money in the next year. And 85 percent of respondents felt that prices rose sharply in the past year, also a new record

DJ...in healthinsurance most people only now may go for a very basic insurance...could even exclude dental care...At the end this "market model" (based on neo-liberal phantasies) will further increase costs for healthcare...There is a -growing- shortage of all kinds of HCW-ers/staff...low pay-high risk...(reminds me of US soldiers told to use food stamps...bizarre !)...

[url]https://nltimes.nl/2022/09/21/first-frost-measured-late-last-night-netherlands[/url] or https://nltimes.nl/2022/09/21/first-frost-measured-late-last-night-netherlands ;

The first recorded instance of ground frost this autumn was measured in the Netherlands late Tuesday night. The temperature on the ground dropped to -1.8 degrees Celsius during the overnight period into Wednesday morning at the weather station in Eelde, Drenthe, according to Weeronline.

There was also frost on the ground at the measuring point near Enschede. There, the temperature dipped to-1.0 degrees at a height of 10 centimeters above the ground.


Broad clearings in the cloud cover enabled the temperatures to drop, according to Weeronline. Officially, the first frost after the summer will be recorded as taking place on 20 September because of the time when the mercury first dipped below freezing at the station in Eelde.

The 28th of September is the average date when frost first occurs after the summer. Last year it happened on 21 September.


The earliest date for post-summer frost is 22 August, a record set in 1973. In 2014, the first frost did not happen until 5 November, the record for the latest first occurrence

DJ...In the last ten years we did often get winters without any (major) snow-or even much frost...However we did see -20C, lots of snow as an exception of the general picture...With people in NL now spending less on heating, good food, healthcare a cold winter can do a lot of healthcare damage...

[url]https://www.dutchnews.nl/news/2022/09/gas-price-cap-will-also-boost-energy-efficiency-experts-say/[/url] or https://www.dutchnews.nl/news/2022/09/gas-price-cap-will-also-boost-energy-efficiency-experts-say/ ; Experts say the government’s decision to introduce a price cap on energy bills will not only help households who are struggling financially but may also encourage people to take more steps to save energy. Details of the deal agreed between the finance ministry and energy companies still have to be finalised, but the plan is expected to save households around €2,000 a year. 

The government will set a maximum unit price for gas and electricity that will cover the first 1,200 m3 of gas and 2,400 kWh of electricity – the annual fuel consumption for an average household. 

Any energy used above that level will be charged at an uncapped rate based on market prices. The government says average household will pay around €290 a month for gas and electricity next year under the proposed price cap. 

The exact rates have not been finalised, but are expected to be around 70 cents for a unit of electricity and €1.50 per cubic metre of gas. This, experts say, makes it financially attractive for people to make sure their energy use stays below the ceiling. Ruut Schalij from energy specialist company eRisk Group told news website Nu.nl he expects to see the ‘biggest savings on energy spending ever’. 

‘Entire families will be able to join in,’ he said. ‘How can we keep our gas use under the 1,200 m3 limit. It will be a great competition, because it can be done.’ The government estimates that around half the country’s eight million households use less energy than the price ceiling covers – but that figure is strongly influenced by the number of people living alone. 

Families Broadcaster RTL says that single person households are likely to remain below the price ceiling and will pay around €205 for gas and electricity in the coming year. Couples living in terraced housing may use slightly more than the government’s estimate, and face bills of around €308 a month. However, families living in bigger houses, who use far more energy than the ceiling limit, will face much higher bills of around €680 a month, RTL said. RTL has a tool to help people estimate how much they will spend on gas and electricity next year.

DJ..16% of social housing has rooms with-still-single glass windows...I would like to see a programm creating more energy efficient houses...Poor urban area's-with allready major health issues-may not get enough help-sink to possibly even third world level...They often do not vote...are NOT represented, already have lots of issues with both government and language...

We may see a major social crisis/protest in those area's...often vaccination level (against all kinds of disease) is low...There was a study in Amsterdam. The richest area's had a survival at birth that was close to the best in the world...while poor area's in Amsterdam did see babies not surviving a first year at third world level...

BA.2.75 is on the rise in NL...at first in the larger cities...later on in other urban area's...Like in other countries it are the poor that pay for pandemics, climate disasters etc much more then the rich. It are the rich-with lots of (long distance) travel, cars etc. that do a lot of the damage...


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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 21 2022 at 11:31pm

DJ,

Let me start with statistics (I used to start scenario's with it...the numbers reflected more reality back then...) [url]https://www.worldometers.info/coronavirus/#main_table[/url] or https://www.worldometers.info/coronavirus/#main_table total reported cases-with lots of countries no longer reporting, or not reporting on a daily basis, 434,092 for wednesday september 21...In total 1,324 CoViD deaths were reported...Based on these numbers...pandemic over ? NO!

Trends Europe-poor testing/reporting cases +6%, Oceania both cases/deaths +17%...other regions often claiming cases -20% or more...These statistics give an indication...France cases +38%, Germany cases +14%, NL cases -10% however based on reporting only twice a week...[url]https://coronadashboard.government.nl/[/url] or https://coronadashboard.government.nl/ (sort of NL-CDC) positive tests +6%, number of people going for a test +8%. Wastewater virusparts +21,2 % BA.2.75 (sub)variants increasing...

[url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time for UK also indicating an upward trend (based on self reporting of symptoms). Twitter has some regions reporting increases (in sewage) others not..yet...

So "news" ;

[url]https://www.coronaheadsup.com/science/superspreader-events/the-queen-of-denmark-tests-positive-for-covid-19-after-that-funeral/[/url] or https://www.coronaheadsup.com/science/superspreader-events/the-queen-of-denmark-tests-positive-for-covid-19-after-that-funeral/ ;

Queen Margrethe of Denmark has tested positive for Covid-19 for the second time in one year after attending the biggest Covid superspreader event in pandemic history – the funeral of Queen Elizabeth II in Great Britain.

The Queen of Denmark, who was photographed just days ago comforting the new King of England, Charles III, has cancelled all of her appointments for the week following the test.

The 82-year-old monarch was one of 2,000 guests who attended Queen Elizabeth II’s state funeral on Monday.

She is Europe’s longest-serving head of state following the British monarch’s death.

She and Queen Elizabeth were third cousins, both being descended from Queen Victoria.

Queen Margrethe has been vaccinated against Covid and last tested positive in February this year when she presented mild symptoms.

BBC.co.uk report

DJ Of course princesses, kings etc. belong to history...A state funeral in the UK as mass spread event ? UK cases -85% based on denial by the UK "government"...

[url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory MPX did get updated...

-[url]https://www.coronaheadsup.com/coronavirus/joe-biden-the-pandemic-is-basically-is-not-where-it-was/[/url] or https://www.coronaheadsup.com/coronavirus/joe-biden-the-pandemic-is-basically-is-not-where-it-was/ ;

“There’s a lot of people — there’s not — the pandemic is, quote, “over,” as I got criticized for saying. But it basically is not where it was.”.

We’re also in a situation where — you know, we have a circumstance where, you know, when we passed the Recovery Act, we ended up being able — there were 2 million people in America had gotten a vaccination. We have over 230 million people are vaccinated. (Applause.)

But, by the way, if you haven’t gotten the booster, get it. There’s a lot of people — there’s not — the pandemic is, quote, “over,” as I got criticized for saying. But it basically is not where it was.

But guess what? The — over 65 to 80 percent of the people who died of the 5,000 dy- — dying never got their shot, never got their booster shot. And it can be — save lives.

The Whitehouse: Remarks by President Biden at a Reception for the Democratic National Committee 

DJ, Indicating the main global problem may be a "political one"....

On medical interventions; 

bad news;

[url]https://www.coronaheadsup.com/health/treatment/remdesivir/remdesivir-induced-emergence-of-sars-cov2-variants-in-patients-with-prolonged-infection/[/url] or https://www.coronaheadsup.com/health/treatment/remdesivir/remdesivir-induced-emergence-of-sars-cov2-variants-in-patients-with-prolonged-infection/ ;

“Remdesivir treatment can increase intra-host genomic diversity and result in the emergence of novel major variant species harboring fixed mutations,”.

We here investigate the impact of antiviral treatments such as remdesivir on intra-host genomic diversity and emergence of SARS-CoV2 variants in patients with a prolonged course of infection.

Sequencing and variant analysis performed in 112 longitudinal respiratory samples from 14 SARS-CoV2-infected patients with severe disease progression show that major frequency variants do not generally arise during prolonged infection. However, remdesivir treatment can increase intra-host genomic diversity and result in the emergence of novel major variant species harboring fixed mutations. This is particularly evident in a patient with B cell depletion who rapidly developed mutations in the RNA-dependent RNA polymerase gene following remdesivir treatment.

Article: Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection

DJ, An "incomplete" vaccination"strategy" also pushed for more new variants better in evading immunity...[url]https://www.coronaheadsup.com/coronavirus/lancet-covid-response-a-massive-global-failure-at-multiple-levels/[/url] or https://www.coronaheadsup.com/coronavirus/lancet-covid-response-a-massive-global-failure-at-multiple-levels/The Lancet Commission looking into the global SARS-CoV-2 pandemic response has levelled some withering criticism at the failure of governments and agencies to tackle the pandemic and uncover its origins.

they keep it polite, governments totally failed in dealing with this pandemic-like they fail in dealing with climate collapse...It reminds me of the (false) story of a monkey getting better results in investments then "investment experts"...

Good news; 

[url]https://www.coronaheadsup.com/health/treatment/research-nasal-saline-irrigation-reduces-severity-in-high-risk-covid-patients/[/url] or https://www.coronaheadsup.com/health/treatment/research-nasal-saline-irrigation-reduces-severity-in-high-risk-covid-patients/ ;

SARS-CoV-2 positive participants initiating nasal irrigation were over 8 times less likely to be hospitalized than the national rate.

Seventy-nine high-risk participants were enrolled. Analyzed by intention-to-treat, by day 28, COVID-19 symptoms resulted in one ED visit and no hospitalizations in 42 irrigating with alkalinization, one hospitalization of 37 in the povidone-iodine group, (1.27%) and no deaths.

Eleven reported irrigation-related complaints and four discontinued use. Symptom resolution was more likely for those reporting twice daily irrigation

Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients

DJ preventing the virus can get into via nose/mouth by "washing it out" (and masks preventing getting the virus in...) is simple, basic, effective !

Maybe later on a part 2...running out of time, not out of info...

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DJ, 

September 24, what will it bring ? (well we learn that tomorrow !)

In vaccines-general discussion yesterday I put a link to Dr. John Campbell [url]https://www.youtube.com/watch?v=WjG3VoX3Ldk[/url] or https://www.youtube.com/watch?v=WjG3VoX3Ldk ;

European Union, Excess mortality hits +16%, highest 2022 value so far UK latest excess death data, updated 16th September https://www.ons.gov.uk/peoplepopulati... https://www.ons.gov.uk/peoplepopulati... WE 2nd September

Dr.J.C. is now facing censorship "outsourced to a private company" youtube;

I said it several months ago. If this doctor gets censored it is a clear indication that something is seriously wrong with free speech. 
He has always used data and facts. We deserve the truth. Those judging misinformation have been giving inaccurate info and making huge mistakes. We deserve to hear the medical opinions of a diverse group and not just one.

Dr.J.C. has the courage to ask questions...on Ivermectin, vaccines...Like I do he is trying to "get a view" on this pandemic. He has much better knowledge in many fields then I do...

[url]https://www.coronaheadsup.com/health/vaccine/pfizer-biontech/dr-john-campbell-on-pfizer-deaths-its-a-scandal-on-par-with-watergate/[/url] or https://www.coronaheadsup.com/health/vaccine/pfizer-biontech/dr-john-campbell-on-pfizer-deaths-its-a-scandal-on-par-with-watergate/ ;

Dr John Campbell on the recent release of Pfizer documents showing that there were 1,223 deaths and 42,086 adverse events associated with the vaccine in the first three months of use.

DJ...so "politics" accept censorship, is outsourcing censorship, to "social media"....

[url]https://southfront.org/its-as-if-voters-want-to-remain-deceived/[/url] or https://southfront.org/its-as-if-voters-want-to-remain-deceived/ ;

Americans today don’t mind invading and occupying a country on the basis of sheer lies. But then Americans become exercised with hatred against Russia when it invaded Ukraine after NATO insisted that Ukraine would become a member (and so there was the real prospect of U.S. nuclear missiles becoming positioned just a five-minute flight to annihilating Moscow) after Obama had couped and grabbed Ukraine in 2014 in what some have called “the most blatant coup in history.” Controlling the media is controlling the mass-mind, in a ‘democracy’. But such a country can’t be any democracy, because its public are mere mental slaves to whatever liars appeal to the biggest percentage of the public’s prejudices. In America, it comes down to Democratic Party lies, versus Republican Party lies. Just like with science itself, democracy can be based only on the truth, the whole truth, and nothing but the truth.

Investigative historian Eric Zuesse’s new book, AMERICA’S EMPIRE OF EVIL: Hitler’s Posthumous Victory, and Why the Social Sciences Need to Change, is about how America took over the world after World War II in order to enslave it to U.S.-and-allied billionaires. Their cartels extract the world’s wealth by control of not only their ‘news’ media but the social ‘sciences’ — duping the public.

DJ, here pandemic, climate change denial meets US/NATO agression in the interest of a small elite with a "pseudo democratic cover"....

I try to understand WHY we are NOT STOPPING THE SPREAD....profits, greed, even getting close to genocide by pandemic on "groups we keep poor"....

"The pandemics are almost over" "because we stop testing and reporting""so case numbers are going down"....with such "leaders" again the pandemic is NOT our main problem !

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 22 2022 at 10:03pm

Part 2, 

From a history point of view one has to relate pandemics with other events; Again the Spanish Flu did get that big because of World War One, mass troop movements, populations in food crises...

The present pandemics, CoViD, MPX, others now see a western "pseudo democratic elite" pushing for regime change wars in Russia, Iran, China...to "bring democrazy to Russian oil and gas"....Healthcare-all around the globe-is overstretched and exhausted...so yet more NATO agression is the last thing the world needs...

[url]https://www.thailandmedical.news/news/breakthrough-mice-study-shows-that-prophylactic-intranasal-administration-of-sars-cov-2-specific-immunoglobulin-y-protects-against-covid-19[/url] or https://www.thailandmedical.news/news/breakthrough-mice-study-shows-that-prophylactic-intranasal-administration-of-sars-cov-2-specific-immunoglobulin-y-protects-against-covid-19 in other words; nasal vaccines...in discussion for almost two years...link [url]https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010782[/url] or https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010782 ;

Abstract

Safe, passive immunization methods are required against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants. Immunization of chickens with antigen is known to induce specific IgY antibodies concentrated in the egg yolk and has a good safety profile, high yield of IgY per egg, can be topically applied, not requiring parenteral delivery. 

Our data provide the first evidence of the prophylactic efficacy of Immunoglobulin Y antibodies against SARS-CoV-2 in mice. Lohmann hens were injected with recombinant SARS-CoV-2 RBD protein; IgY-Abs were extracted from the eggs and characterized using SDS-PAGE. Antiviral activity was evaluated using plaque reduction neutralization tests. 

In additional experiments, IgY-RBD efficacy was examined in mice sensitized to SARS-CoV-2 infection by transduction with Ad5-hACE2 (mild disease) or by using mouse-adapted virus (severe disease).

 In both cases, prophylactic intranasal administration of IgY-Abs reduced SARS-CoV-2 replication, and reduced morbidity, inflammatory cell infiltration, hemorrhage, and edema in the lungs and increased survival compared to control groups that received non-specific IgY-Abs. 

These results indicate that further evaluation of IgY-RBD antibodies in humans is warranted.

Author summary

We report the generation, characterization and antiviral activity of egg yolk derived IgY-Abs against the SARS-CoV-2 Receptor Binding Domain. Using two different models of murine SARS-CoV-2 infection, we show that intranasal prophylactic administration of IgY-Abs reduced viral replication, and reduced inflammatory cell infiltration, hemorrhage, and edema in the lungs.

DJ...Even with "politics" going for who can make profits out of nasal vaccines -in most "western" countries it is good to see nasal vaccines may offer a way out...No doubt countries like India, China, Russia can provide most of the world with effective nasal vaccines-with some further development. Without going for profits for shareholders...

For that matter South Africa, Cuba-Iran cooperation offers hope for the world...

[url]https://www.coronaheadsup.com/coronavirus/research-all-covid-19-infections-include-a-wide-mix-of-sars-cov-2-virus-variants/[/url] or https://www.coronaheadsup.com/coronavirus/research-all-covid-19-infections-include-a-wide-mix-of-sars-cov-2-virus-variants/ ;

A fascinating peer reviewed research study that concludes that ALL Covid infections include multiple variants of the virus!

The researchers also note that “genetic variants observed in low frequency in SARS-CoV-2 infections can be early indicators of new strains responsible for later transmission surges”.

Researchers at Case Western Reserve University found wide genetic variation in SARS-CoV-2 viruses among 360 patients whose viral infections were genetically sequenced, showing that all individual infections include multiple variants of the virus.

The researchers noted that reporting about the virus usually highlights a single dominant strain, which leads to under-reporting virus genetic variation and can have serious consequences in public-health planning and response.

“Our work brings attention to the complexity of infectious diseases that is often over-simplified when considering only the most abundant virus in an infection, and we demonstrate the importance of examining the variations that are historically considered noise. We see that genetic variants observed in low frequency in SARS-CoV-2 infections can be early indicators of new strains responsible for later transmission surges.”

Press release: Researchers at Case Western Reserve University show that all COVID-19 infections include a wide mix of SARS-CoV-2 virus variants 

Research: COVID-19 infection and transmission includes complex sequence diversity

DJ, based on this knowledge..could we have missed CoViD spread in pigs infected with African Swine Fever (ASF) during the global ASF "pigdemic" 2018-2020 ? Did pigs not only get ASF, but also a pre-CoViD-19 virus mutating towards spread in humans ? [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory MPX has to be seen against a CoViD pandemic background...

CoViD is resulting in less immunity protection...since at least 1/4 of the global human population may have had CoViD it will result in "more room"for other diseases to spread...

[url]https://www.coronaheadsup.com/health/long-covid/long-covid-impaired-lung-function-for-months-after-infection/[/url] or https://www.coronaheadsup.com/health/long-covid/long-covid-impaired-lung-function-for-months-after-infection/ ; Two different research articles out recently give graphic details of the lung damage that can be caused in both adults and children after a Covid infection. Up to half of all patients who had contracted Covid suffered from persistent pulmonary dysfunction.

and [url]https://www.thailandmedical.news/news/canadian-study-shows-even-after-a-year-up-to-41-percent-of-post-covid-individuals-still-have-autoantibodies-that-causes-autoimmune-issues[/url] or https://www.thailandmedical.news/news/canadian-study-shows-even-after-a-year-up-to-41-percent-of-post-covid-individuals-still-have-autoantibodies-that-causes-autoimmune-issues

it is quite easy to catch the virus...but once the virus is "in" it can do a lot of-long lasting-damage, with a perspective of the virus(variants) hiding in the body...for years. 

AGAIN STOP THE SPREAD !!!!! So far vaccines did not stop infection, spread, may have done a good job in limiting disease (while also causing vaccine related problems). So-is there a way out of this pandemic ? YES-but it has to include "zero CoViD" ...yet "west wants to save the economy-profits"....even if this means pandemics destroying the economy...








Here we go.... Again... 👉Weekly #COVID19 hospital admissions in England🏴󠁧󠁢󠁥󠁮󠁧󠁿 ⚠️4,003 vs 3,418 ⚠️+17% in just a week ‼️

And yes the CoViD winterwave has started, BA.2.75 subvariants increasing...Politics has to reduce testing if they want to hide reality...

End of part 2

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 24 2022 at 5:48am

DJ, 

Limited "new news" on CoViD...[url]https://www.coronaheadsup.com/asia/japan/japan-more-than-800-infected-with-covid-after-dance-festival-superspreader-event/[/url] or https://www.coronaheadsup.com/asia/japan/japan-more-than-800-infected-with-covid-after-dance-festival-superspreader-event/

819 people were found to have been infected with coronavirus after a summer dance festival turned into a Covid superspreader event.

The Awa Odori in Tokushima City is originally a Buddhist Bon dance, and one of Japan’s most famous summer festivals. The marching dance festival was carried out on the city streets from August 12 through 15. It took place on its full scale for the first time in three years, with skilled dance groups performing and many tourists from outside Tokushima Prefecture joining the dance processions.

At an organizing committee meeting on Thursday, the results of a COVID-related survey of 123 dance groups were reported. These groups had taken part in this year’s festival.

The survey shows that of the members of the 86 groups that responded, 819 people were confirmed to have been infected with the virus between August 11 through 25, which included the festival period.

NHK Japan report

reminds me of another recent London-UK funeral mass event...[url]https://www.coronaheadsup.com/science/superspreader-events/the-queen-of-denmark-tests-positive-for-covid-19-after-that-funeral/[/url] or https://www.coronaheadsup.com/science/superspreader-events/the-queen-of-denmark-tests-positive-for-covid-19-after-that-funeral/ ...

Another major story has to be [url]https://www.coronaheadsup.com/health/ebola/uganda-ebola-death-toll-rises-to-12/[/url] or https://www.coronaheadsup.com/health/ebola/uganda-ebola-death-toll-rises-to-12/

At least 12 people have died from the Ebola Sudan Virus in Uganda’s Mubende district, according to Ugandan health authorities, the Uganda Radio Network reported.

As of Tuesday morning, the death toll stood at eight people, but officials say that two more people died on Wednesday morning in the hospital while two others died in a village in Madudu Sub County, the same area where the first case was confirmed on Monday. The first seven people, including an enrolled nurse, died before the outbreak was confirmed.

Dr. Emmanuel Paul Batibwa, the director of the Mubende Regional Referral hospital, says that 10 other people are currently admitted with severe signs of Ebola. He added that four contacts of a victim who died in the Kyaka refugee settlement have also been sent to Mubende hospital for screening and that their samples have been sent to the Uganda Virus Research Institute.

Radiotamazuj.org report

 

CNN are reporting that one of the dead is a one-year-old child.

CNN report

DJ, regional spread in Africa very likely...DRC high risk...








BQ.1.1 now has been overtook in the lead by BA.2.3.20 ( spotted it very early from really 3-4 seqs), XBB is roaring behind these two. https://cov-spectrum.org/collections/24         

DJ, also other variants showing up/increase of spread...so YES-winterwave is starting, NO official statistics will NOT show that....[url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time self reported symptoms app, [url]https://coronadashboard.government.nl/landelijk/rioolwater[/url] or https://coronadashboard.government.nl/landelijk/rioolwater can be better indicators...

-The international situation deserves major attention...I see a trend (also in Sweden, Italy elections) towards putting national interests first...A lot of countries are tired of endless US wars...[url]https://www.zerohedge.com/political/us-empire-accelerating-toward-global-conflict-two-fronts-johnstone[/url] or https://www.zerohedge.com/political/us-empire-accelerating-toward-global-conflict-two-fronts-johnstone

On paper it looks completely irrational for the US empire to be ramping up aggressions against two powerful military and economic forces simultaneously, but it’s undeniable at this point that that is what’s happening. Clearly our rulers have some kind of strategy for how they’re going to see this through, though it remains to be seen whether that strategy is the desperate Hail Mary pass of a dying empire or a potentially highly effective plan using tools that aren’t currently visible to the public.

Either way, it looks like it’s probably a good time to relish human life on this planet while it’s here to be relished.

DJ...Russia, China do have a strategy...both on CoViD and on national interests...The "western friends" of the US would do much better if they started asking serious questions on US plans...(More in latest news)...

I keep at at this for now...weekend

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DJ,

- In latest news/sept. 24 I did post a last comment. Mayby one major point, while the US is confronting Russia, China India has an economic growth of 7,5%...doing lots of trade-via-Iran-with Russia...The "multi-polar" world can not be stopped..US ($) dominance is over...

-[url]https://forum.arctic-sea-ice.net/index.php/topic,3721.750.html[/url] or https://forum.arctic-sea-ice.net/index.php/topic,3721.750.html trying to get a view on Arctic melting...it may be hard to define the end of melting, begin of Arctic re-freezing...Some Arctic area's may still face melt...others are already refreezing...Also the definition of "ice" matters [url]http://arctic-news.blogspot.com/2022/09/blue-ocean-event-2022.html[/url] or http://arctic-news.blogspot.com/2022/09/blue-ocean-event-2022.html 

[url]https://www.tropicaltidbits.com/[/url] or https://www.tropicaltidbits.com/ and [url]https://www.nhc.noaa.gov/[/url] or https://www.nhc.noaa.gov/ "Ian" may hit the US as a strong hurricane wednesday/thursday..."remnants of Florian" are doing a lot of damage in the east of Canada...Alaska, Greenland did see major storms...

India now facing extreme weather...Pakistan still in floods...Climate collapse very likely only getting worse...

-So now pandemics...[url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory even Greenland reported 2 cases...confirmed/suspected cases now close to 72,000 with testing/reporting "poor"...DJ-I expected MPX to increase with schools reopening...even an incubation time of 3 weeks may not explain why numbers do not go up faster...Do children get less symptoms, misdiagnosed, or simply MPX in children not getting reported ? [url]https://twitter.com/RolandBakerIII[/url] or https://twitter.com/RolandBakerIII among many others has a lot of good info/links...








At  we've been sequencing #monkeypox virus since July 2022. In our latest preprint we analyze  the first 109 MPXV sequences we generated for #washingtonstate tl;dr . community spread, multiple introductions, and one case of co-infection by multiple #MPXV strains

On CoViD ;


Replying to 
And several more BQ.1, BQ.1.1 and BA.2.3.20, which seem to grow faster than BJ.1 worldwide!

DJ BA.4.6 becoming dominant ??? 

[url]https://www.coronaheadsup.com/coronavirus/switzerland-red-foxes-infected-with-sars-cov-2/[/url] or https://www.coronaheadsup.com/coronavirus/switzerland-red-foxes-infected-with-sars-cov-2/ ...the more spread and time the more also animals will catch (a form of) the virus..some may also spread it...(two foxes -march 2022)

[url]https://www.coronaheadsup.com/health/vaccine/pfizer-biontech/pfizer-ceo-fighting-second-covid-infection-in-5-weeks/[/url] or https://www.coronaheadsup.com/health/vaccine/pfizer-biontech/pfizer-ceo-fighting-second-covid-infection-in-5-weeks/ ;DJ testing positive twice...mid august and late september-had 5 vaccines...no doubt limiting severe disease NOT stopping virus spread or reinfection...

The ADE nightmare...

[url]https://www.coronaheadsup.com/science/ade/preprint-reevaluation-of-antibody-dependent-enhancement-for-sars-cov-2-treatments/[/url] or https://www.coronaheadsup.com/science/ade/preprint-reevaluation-of-antibody-dependent-enhancement-for-sars-cov-2-treatments/ ;

A new preprint looking at the evidence for antibody-dependent enhancement (ADE) is getting a LOT of attention online – we link to it below so that you can read it for yourself.

In the present study, we reevaluated whether the approved therapeutic Ab drugs (casirivimab, imdevimab, and sotrovimab26,27) have any potential to cause ADE even in FcR- and ACE2-positive cells. In addition, we investigated sera from mRNA (Moderna)-vaccinated individuals in terms of ADE-causing potential by using the same double-positive cells. Here, we show that the casirivimab and imdevimab mAbs have the ability to induce ADE, but sotrovimab does not. Furthermore, some sera from individuals vaccinated with the mRNA vaccine targeting the S-protein also exhibited ADE potential against infection with the original strain. All sera examined, including sera showing neutralizing activity against the original Wuhan strain of SARS-CoV-2, exhibited no neutralizing activity against Omicron. Rather, some ADE activity was observed in some sera.

Although sera collected from mRNA-vaccinated individuals exhibited neutralizing activity, some sera gradually exhibited dominance of ADE activity in a time-dependent manner. None of the sera examined exhibited neutralizing activity against infection with the Omicron strain. Rather, some ADE of Omicron infection was observed in some sera. These results suggest the possible emergence of adverse effects caused by these Abs in addition to the therapeutic or preventive effect.

 

Preprint: Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells

DJ...CoViD-19/SARS-2 seems to develop from evasion of immunity to even using immunity to spread...I am NOT an expert...but on what I read a.o. on twitter the present (lack of) strategy to limit CoViD is resulting in much worse CoViD variants...A bit like fighting a 10 acre wildfire-resulting in a 50 acre wildfire...

[url]https://www.thailandmedical.news/news/post-covid-fatigue-associated-with-increased-expression-of-inflammatory-genes-in-monocytes,-serum-pro-inflammatory-cytokines-and-increased-cd8-t-cells[/url] or https://www.thailandmedical.news/news/post-covid-fatigue-associated-with-increased-expression-of-inflammatory-genes-in-monocytes,-serum-pro-inflammatory-cytokines-and-increased-cd8-t-cells DJ-Some "experts" now quite openly linking "long/chronic CoViD' with ME/CFS...[url]https://www.medrxiv.org/content/10.1101/2022.09.15.22279970v1[/url] or https://www.medrxiv.org/content/10.1101/2022.09.15.22279970v1 but again; long/chronic CoViD can manifest itself in lots of ways...

Chronic CoViD may have (several subvariants) long term infection..

Long CoViD may have gotten rid of the virus but still see lots of damage/auto-immune (over) reaction...

(In my non-exper view). "Mild CoViD' could still result in long term problems...

[url]https://www.thailandmedical.news/news/cohort-study-finds-that-fish-oil-supplements-reduces-the-risk-of-covid-19-severity[/url] or https://www.thailandmedical.news/news/cohort-study-finds-that-fish-oil-supplements-reduces-the-risk-of-covid-19-severity DJ the correct use of suplements may limit risks, gurgling/getting throat (and nose) clean-possible virus out also may limit risks...

Masks, avoiding crowds help...a lot of non pharma interventions may do a much better job then the present "vaccinate-but-spread" (insane) strategy...

Non pharma Interventions do not make a lot of profits...but may be able to limit disease spread much better then the present "pseudo-strategy". I think co-infection with (lots of) diseases may bring disaster...Vaccines are NOT the way to limit that ! You need a strategy to STOP THE SPREAD !!! 

We keep importing all kinds of diseases, virus-fly-for-free insanity !!!

So [url]https://www.thailandmedical.news/news/sars-cov-2-presents-its-fall-and-winter-2022-variant-collections-featuring-ba2-75-2,-bq-1-1,-bw-1,-xbb,-bu-1,-br-2,-bm-1-1-1,-ca-1,-bj-1-and-bn-1[/url] or https://www.thailandmedical.news/news/sars-cov-2-presents-its-fall-and-winter-2022-variant-collections-featuring-ba2-75-2,-bq-1-1,-bw-1,-xbb,-bu-1,-br-2,-bm-1-1-1,-ca-1,-bj-1-and-bn-1 prepare for an even worse pandemic winter bringing all kinds of diseases with less immunity protection...

We could have avoided this disaster but we did not...

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
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part 2

But... What you really want to do is prevent becoming infected in the first place. Each time you get infected or reinfected there is a chance you can develop long-term consequences or possibly permanent damage to your body as COVID-19 is not a cold. 34/

-









While being vaccinated can reduce the chance of developing Long COVID, even 1 in 10 vaccinated people who got infected developed Long COVID. 35/

-

Infection puts people at increased risk of heart attack, stroke, cardiovascular issues, blot clots, brain damage, neurological and many more issues even months after infection. This happens in both adults and children, and even with mild infections. 36/

-

This means that we can't rely on vaccines alone, but need to invest in additional measures that are variant proof. Part 2 will discuss how the virus is transmitted and ways to help reduce the risk of becoming infected. 37/

-in other words; STOP THE SPREAD !!!!








BQ.1.1 now has been overtook in the lead by BA.2.3.20 ( spotted it very early from really 3-4 seqs), XBB is roaring behind these two. https://cov-spectrum.org/collections/24         

DJ...I try to follow and understand developments of this pandemics...Once new variants did get new names-by the WHO...Now the WHO sticks to naming all new variants "Omicron" resulting that "BA" types now see BQ, XBB,BM, BW etc subtypes-possibly also with a BA name...very likely also "Omicron" but for an "interested non expert" by now impossible to follow...








“Maybe it would be better to catch ’rona and get it over with, now that I’m fully vaccinated?” Chris remembers speculating. He did. Chris came down with a scratchy throat. 12 days he got hit by congestive heart failure.

DJ...I have been limiting contacts since march 2020...go for limiting risks without locking myself up...Why do governments, WHO, (E)CDC etc. fail public health ? "Saving the economy" in fact is destroying that economy...Here in NL it did increase internet sales...with that low pay jobs replacing better paid jobs...[url]https://nltimes.nl/2022/09/24/netherlands-give-bonuses-full-time-workers-fight-staff-shortages[/url] or https://nltimes.nl/2022/09/24/netherlands-give-bonuses-full-time-workers-fight-staff-shortagesThe Cabinet can take big steps towards solving the staff shortages that now affect all sectors of the Dutch labor market by making it worth it for people to work more,

and [url]https://nltimes.nl/2022/09/23/food-banks-hague-running-food-people-need-help[/url] or https://nltimes.nl/2022/09/23/food-banks-hague-running-food-people-need-help 

"Saving the economy" did result in sick leave 10%+ of staff in some sectors, increase of poverty (also as a result of increasing wars...)..Here in NL people may be forced to spent less on health insurance-while health risks increase. Health care is overstretched...in many countries the coming winter wave may bring a "black scenario" with not enough healthcare capacity for all...

This could result in triage;

-"light" cases may  get medication, basic info for self treatment

-"moderate cases" may see selection (a.o. by age, healthstatus, years of live saved...)  and be able to get care

-"severe cases" may be "helped to die without major suffering" 

We did see discussion on these worst case scenario's in the past winter waves...the coming winter-wave will bring us even closer...








This saga is horrible & sad.  has done an excellent, selfless job educating the public about indoor air & warning about risky technologies. She is being sued for defamation for $180 MILLION w/ $400,000 expected legal fees! Pls share & help.

DJ...does insanity has limits ? (twitter use on this forum has...)

We cannot solve our problems with the same thinking we used when we created them.
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DJ, 

Last few sentences of my 2nd yesterday post went missing....twitter and this forum end up in a fight...

-I will try to "keep this forum alive" for another few months...Maybe not posting anything could start others posting ? Am I in the way for others ? There is a need for info on "pandemics" with a CoViD-winter wave on the rise, a possible bad flu, MPX and lots of other-possible-unwelcome surprises...

As always I hope to be wrong...healthproblems decrease etc...I just do not expect that and use this forum to make my mind up on why...

-In Ukraine Russia would not have organized the referenda in 4 regions if they did not expect to win them. Tomorrow it will be the last day of voting...Some indication that after sept.27 Russia will put an ultimatum to Ukraine to leave the four oblasts/regions - soon Russia will declare them-like Crimea-part of Russia. 

Why does it matter ?  

1. Those four regions-as part of Russia-will see the regular Russian Army moving in..

2. Any attack on those area's will be seen as an attack on Russia (may even bring a [url]https://en.wikipedia.org/wiki/Collective_Security_Treaty_Organization[/url] or https://en.wikipedia.org/wiki/Collective_Security_Treaty_Organization reaction.

3. Some countries (North Korea, Syria) may accept that step...it will tell Russia something of what support they have...

It will not end the war...

Pandemics;

Yesterday had some "horror news" [url]https://www.thailandmedical.news/news/sars-cov-2-presents-its-fall-and-winter-2022-variant-collections-featuring-ba2-75-2,-bq-1-1,-bw-1,-xbb,-bu-1,-br-2,-bm-1-1-1,-ca-1,-bj-1-and-bn-1[/url] or https://www.thailandmedical.news/news/sars-cov-2-presents-its-fall-and-winter-2022-variant-collections-featuring-ba2-75-2,-bq-1-1,-bw-1,-xbb,-bu-1,-br-2,-bm-1-1-1,-ca-1,-bj-1-and-bn-1 and [url]https://www.coronaheadsup.com/science/ade/preprint-reevaluation-of-antibody-dependent-enhancement-for-sars-cov-2-treatments/[/url] or https://www.coronaheadsup.com/science/ade/preprint-reevaluation-of-antibody-dependent-enhancement-for-sars-cov-2-treatments/ 

Today [url]https://www.coronaheadsup.com/science/variants/omicron/ba-2-75-2/ba-2-75-2-and-bq-1-1-approaching-sars-1-level-escaping-capability/[/url] or https://www.coronaheadsup.com/science/variants/omicron/ba-2-75-2/ba-2-75-2-and-bq-1-1-approaching-sars-1-level-escaping-capability/ comes on top of that...

A new Twitter thread out today from Yunlong Cao gives further details about the variants BA.2.75 and BQ.1.1.

“Updating information regarding convergent variants BA.2.3.20, BN.1, BA.2.10.4, BN.2.1, BA.4.6.1, BQ.1, BQ.1.1. In short, BA.2.75.2 and BQ.1.1 are the most antibody-evasive convergent variants tested, far exceeding BA.5 and approaching SARS-CoV-1 level. (1/4)”

 

“BA.2.75.2 is slightly more evasive than BQ.1.1 against plasma from BA.2/BA.5 breakthrough infections. Its due to the enriched NTD-NAbs elicited by BA.2/BA.5 infections, which BQ.1.1 can’t escape. Note that these variants are approaching SARS-CoV-1 level escaping capability. (2/4)

 

“As expected, BQ.1.1 escapes Evusheld and bebtelovimab, making all clinically available antibody drugs ineffective. BQ.1.1 and BA.2.75.2 both displayed sufficient hACE2 binding capability. (3/4)”

 

“We should be able to update information on BU.1, BR.2, BM.1.1.1, CA.1, and XBB within two weeks. I agree with @CorneliusRoemer that XBB will be the most immune-evasive convergent variant for now, since it should be able to escape the majority of both NTD/RBD NAbs. (4/4)”

 

Do we have any idea what protection bivalent [vaccines] will afford against these?

“I don’t think the current WT/BA.1 or WT/BA.5 bivalent vaccines would be very effective against those convergent variants, based on the released mouse vaccination data.”

 

Yunlong Cao has already featured in two other posts on Coronaheadsup.com about BA.2.75.2 and other variants of interest. You can find the posts here and here

 

Cornelius Roemer: “BQ.1.1 is showing quite some growth, especially in England where the first sample was submitted 9 days ago and now there are already 28 sequences. I hope there is some sort of biased sampling going on. Otherwise this doesn’t look good.”

DJ, Indications are simply very bad....

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 26 2022 at 12:21am

part 2

[url]https://www.youtube.com/watch?v=_q0XvfIqRJY[/url] or https://www.youtube.com/watch?v=_q0XvfIqRJY Alexander Mercouris/AM; Russia Prepares Knock Out Blow, Ukraine Offensive Stalls; Rumours of Saudi Peace Deal Giving Donbass, Kherson to Russia

DJ, AM discussing a possible peace initiative from Saudi Arabia/GCC [url]https://en.wikipedia.org/wiki/Gulf_Cooperation_Council[/url] or https://en.wikipedia.org/wiki/Gulf_Cooperation_Council (and Türkiye). 

AM expects US/UK/Ukraine,Baltics, Poland (DJ-Finland) may be against any talks with Russia...DJ, However European elections in Sweden, Italy press (most) EU "leaders" for damage control. [url]https://www.zerohedge.com/political/nancy-pelosi-savagely-booed-nyc-festival-doesnt-bode-well-dems-ahead-mid-terms[/url] or https://www.zerohedge.com/political/nancy-pelosi-savagely-booed-nyc-festival-doesnt-bode-well-dems-ahead-mid-terms US mid term elections, UK breaking up may even change US, UK position....

The (West) European economy is close to collapse...high inflation, growing unrest...the Ukraine war is going on to long, becoming a major burden for most of the EU...

AM also mentioned the military perspective. Russia's next step could be major offensives to capture/annex even more of Ukraine...Odessa, Nikolayev, Charkov...Ukraine was better of with the agreements made in Türkiye...even better if they could have avoided this war. The longer the war goes on the more parts of Ukraine end up as parts of Russia...

-[url]https://www.tropicaltidbits.com/[/url] or https://www.tropicaltidbits.com/ and [url]https://www.nhc.noaa.gov/refresh/graphics_at4+shtml/042342.shtml?cone#contents[/url] or https://www.nhc.noaa.gov/refresh/graphics_at4+shtml/042342.shtml?cone#contents "Ian" is expected to bring major damage to the SE of the US...The Philippines did see a typhone killing several, lots of damage...

DJ-Climate collapse could bring an end to a clear (Ant)Arctic pattern of "melting/freezing-season"....storms could bring above melting temperatures/seawater into (Ant)Arctic zones in a way we did not see before....

-








A few days later and we have some more data to support a growing suspicion that the US is actually entering a second wave of monkeypox cases. We'll be watching this closely and posting updates throughout next week. https://monkeypoxtracker.net/countries/US


DJ...is this second wave related to schools/workplaces reopening ? [url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Statistics[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Statistics may give some info...[url]https://www.paho.org/en/documents/paho-monkepox-sit-rep[/url] or https://www.paho.org/en/documents/paho-monkepox-sit-rep 

Post-COVID-19 syndrome: retinal microcirculation as a potential marker for chronic fatigue https://medrxiv.org/content/10.1101/2022.09.23.22280264v1

link;[url]https://www.medrxiv.org/content/10.1101/2022.09.23.22280264v1[/url] or https://www.medrxiv.org/content/10.1101/2022.09.23.22280264v1 ;

Abstract

Post-COVID-19 syndrome (PCS) summarizes persisting sequelae after infection with the severe-acute-respiratory-syndrome-Coronavirus-2 (SARS-CoV-2). PCS can affect patients of all covid-19 disease severities. As previous studies revealed impaired blood flow as a provoking factor for triggering PCS, it was the aim of the present study to investigate a potential association of self-reported chronic fatigue and retinal microcirculation in patients with PCS, potentially indicating an objective biomarker.

A prospective study was performed, including 201 subjects: 173 patients with PCS and 28 controls. Retinal microcirculation was visualized by OCT-Angiography (OCT-A) and quantified by the Erlangen-Angio-Tool as macula and peripapillary vessel density (VD). Chronic Fatigue (CF) was assessed with the variables ‘Bell score’, age and gender. The VD in the superficial vascular plexus (SVP), intermediate capillary plexus (ICP) and deep capillary plexus (DCP) were analyzed considering the repetitions (12 times). Taking in account of such repetitions a mixed model was performed to detect possible differences in the least square means between different groups of analysis.

An age effect on VD was observed between patients and controls (p<0.0001). Gender analysis yielded that women with PCS showed lower VD levels in SVP compared to male patients (p=0.0015). The PCS patients showed significantly lower VD of ICP as compared to the controls (p=0.0001, [CI: 0.32; 1]). Moreover, considering PCS patients, the mixed model reveals a significant difference between chronic fatigue (CF) and without CF in VD of SVP (p=0.0033, [CI: -4.5; -0.92]). The model included age, gender and the variable ‘Bell score’, representing a subjective marker for CF. Consequently, the retinal microcirculation might be an objective biomarker in subjective-reported chronic fatigue of patients with PCS.

DJ, If bloodflow to the eye can be measured as being different in post-CoViD patients how is blood flow to other organs effected ?

End of part 2

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jjjjllllggggzzzzbb Quote  Post ReplyReply Direct Link To This Post Posted: September 26 2022 at 1:04pm

100% treatment of coronavirus and other infectious diseases with monoclonal antibodies. Treatment without contraindications and I will be able to transfer this ability to people.

Give me a chance to beat the coronavirus.

I have the strongest acquired t-cell immunity. Purposefully strengthen the immune system for more than 7 years. During all the time, lymphocytes were from 44 to 56%. Immunity is constantly stressed due to two rare internal diseases.

How did I achieve such immunity

My mother is a retired cook by profession. I eat 5 times a day only healthy food by healthy food I mean every morning I eat milk porridge, every day I eat at least 200 grams of vegetables and fruits, every evening I drink kefir, every day I drink metformin medicine. I do not work on disability. Due to illness, all kinds of sports are prohibited except for an exercise bike. I do sports on an exercise bike every day.

To prove that I have t-cell immunity. I can provide the test results of 5 immunograms. In 3 immunograms, lymphocytes and t-cells are significantly exceeded in abs.number / ml, I made an immunogram at the Almetyevsk AIDS Center.1 the immunogram was made at the end of August by the polyclinic of PJSC Tatneft after much persuasion. 2 I did an immunogram 20 days later at the request of a local immunologist . 3 I did an immunogram half a year later on the day after the illness. The 2nd and 3rd immunogram was paid for by the polyclinic where the analysis was done, they became interested that my lymphocytes and t-cells were exceeded . In the second and fifth immunogram, the immunologist wrote something.

As proof that acquired immunity. I did 7 blood tests made according to the leukoformula lymphocytes above normal neutrophils below normal, I did it in a private laboratory Invitro.

Monoclonal antibodies are the strongest weapon against the coronavirus.Monoclonal antibodies are produced from immune cells.

I have had coronavirus 2 times. 1 time in August for 4 days in super light form. On July 26, the deputy heads were healthy.the doctor of the polyclinic of PJSC Tatneft will prove. On August 1, I was at his reception again, I looked sick and he advised me to go home. I was ill at home with symptoms of coughing, sneezing, runny nose and fever On August 3, I did PCR at the Almetyevsk polyclinic of PJSC Tatneft, whether I am sick or not.On the 4th day, a nurse from the polyclinic came, first she communicated with me in a mask and then she made sure that I was healthy and continued to communicate without a mask. By the way, my mother also had a mild coronavirus in 10 days, but with the loss of sense of smell, I accidentally learned about 2 infections from doctors, antibodies to coronavirus spontaneously rose from 204 to 316. I've had the coronavirus 3 times in September 20, the symptoms were sore throat 1 day, a headache 2 days and a runny nose 4 days and I think a new mutation

If my immunity was able to protect me, then I can probably transfer this ability to people. My medicine cures in 3 days, the analogue of my medicine cured the former president of the United States. And as a vaccine, its effect is unlimited in time.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 27 2022 at 2:51am

DJ, 

Some points;

-[url]https://www.tropicaltidbits.com/[/url] or https://www.tropicaltidbits.com/ following "Ian" developing into a major hurricane on its way to hit Florida/US...May bring very serious damage/flooding...

-A.o. Alexander Mercouris on "Ukraine"; Today last day of referendum. The four regions will start the procedure to be included into Russia tomorrow. Russia could declare war september 30-hoping to end this war before december 31. DJ-I think France/Germany may be involved-via Saudi Arabia (and Türkiye ?) - in talks with Russia on Ukraine...(sort of Minsk-3 like ?) After Sweden and Italy elections bringing a win for extreme right parties at least part of the EU is shifting...US, UK, Poland may not be willing to move...Very likely the "west" may see a split...

The economic damage is getting that serious the "west" has to make a move...

Pandemic(s)

[url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory may be facing very major under reporting...









Heavy-tailed sexual contact networks and monkeypox epidemiology in the global outbreak, 2022: MSM with the highest number of partners are key to keeping R0<1  (H/T )

-









In other words a very small portion of people have an extreme number of partners and this has the largest affect on collective behavior i.e. an R0 which is much higher than one. And this hypothesis fits the data better than alternate hypotheses.

link; [url]https://www.science.org/doi/full/10.1126/science.add4507[/url] or https://www.science.org/doi/full/10.1126/science.add4507 DJ-A small group going for "super spread" may develop into massive spread via aerosol, contact of surface etc...Under diagnosing, under reporting may be a major problem...People may "sit it out" only go for help if they get very ill...Still could spread the virus via aerosols, blood/pus...I think schools/workplaces reopening-early this month-by now (incubation 3 weeks) would bring an increase of cases...but it may be hard to detect if people do not go for help...

[url]https://www.coronaheadsup.com/health/who/who-the-end-of-the-pandemic-is-still-a-long-way-off/[/url] or https://www.coronaheadsup.com/health/who/who-the-end-of-the-pandemic-is-still-a-long-way-off/ ;

Just two weeks ago, WHO Director Tedros Ghebreyesus told reporters that the world had “never been in a better position to end the pandemic”, and “the end is in sight.”.

Today, the message from Tedros has changed again. Here is the revised message:

We have spent two and a half years in a long, dark tunnel and we’re just beginning to glimpse the light at the end of that tunnel, but it is still a long way off and the tunnel is still dark with many obstacles that could trip us up if we don’t take care.

We all need hope that we can and we will get to the end of the tunnel and put the pandemic behind us but we’re not there yet. We’re still in the tunnel and we will only get to the end by focusing on the path ahead and by moving forward with purpose and care.purpose and care.

WHO: Monkeypox, COVID-19 & Other Global Health Issues Virtual Press Conference

 

This change of tone from the World Health Organisation comes just days after American President, Joe Biden, also walked back his comments that the pandemic was over.

 

Our question is this; why was the disastrous “the pandemic is over” message disseminated globally just days before the start of what could be the worst winter wave in pandemic history?
Mixed messages don’t save lives…

DJ...information/communication may be the #1 tool in any crisis...But sending stupid info does do a lot of damage...

[url]https://www.thailandmedical.news/news/latest-sars-cov-2-bq-1-1-and-ba-2-3-20-variants-driving-exponential-daily-new-infections-and-hospitalizations-across-europe-with-high-incidences-of-ar[/url] or https://www.thailandmedical.news/news/latest-sars-cov-2-bq-1-1-and-ba-2-3-20-variants-driving-exponential-daily-new-infections-and-hospitalizations-across-europe-with-high-incidences-of-ar ds. (TMN)

DJ A.o. link to [url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time self-reporting UK CoViD cases now above 2 million and going up...[url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table Europe cases +3% (with very poor -often not daily- reporting resulting in "false" statistics...) Oceania cases +9% (they are now in spring...) 

TMN mentioning London UK hospitals reaching their limits...UK "gov" simply denying the crisis...the article is full of links...

DJ-It would fit in with the exponential model...NOT stopping the spread, vaccines only limiting disease-in that way at best buying time...There may be discussion on how many people did catch CoViD...some "experts" claim all of us must have had "contact" with CoViD by now...others go for "billions"...Vaccines-looking at statistics-did save lives...for CoViD deaths within 28 days after infection...however excess deaths may indicate there arte major problems...

Other diseases [url]https://www.thailandmedical.news/news/breaking-long-covid-is-a-misnomer-the-conditions-are-being-caused-by-viral-persistence-and-viral-peptides-similar-to-retrotransposons-and-introns[/url] or https://www.thailandmedical.news/news/breaking-long-covid-is-a-misnomer-the-conditions-are-being-caused-by-viral-persistence-and-viral-peptides-similar-to-retrotransposons-and-introns the CoViD-virus variants staying in the body doing damage -certainly in combination-could make this winter a major challenge... 

-There is some discussion on timing of vaccines [url]https://www.statnews.com/2022/09/09/doubling-up-on-covid-booster-flu-shot-may-have-downside/[/url] or https://www.statnews.com/2022/09/09/doubling-up-on-covid-booster-flu-shot-may-have-downside/ ...If you want to vaccinate a lot of people in a short time it could be usefull to combine a CoViD-vaccination with a flu-vaccination...However some people have serious healthissues after the CoVid vaccination...so they may have hesitations on getting both vaccines in one time...It may also be the first time-in many countries-that large scale co-vaccinations (flu/CoViD0 are getting organized...So there may be limited data on (more) side effects...

[url]https://flunewseurope.org/[/url] or https://flunewseurope.org/ indicates "limited flu activity" in Europe; 

  • Influenza activity has increased though remains at interseasonal levels.
  • Israel and Spain both have an influenza virus positivity in sentinel primary care specimens of at least 10%.
  • Estonia, Georgia, Germany, Greece, the Netherlands, UK (Northern Ireland) and Sweden reported sporadic geographic activity, Malta reported local activity, Scotland reported regional activity and Portugal reported widespread activity. 
  • Azerbaijan, Georgia, Luxembourg and Slovenia reported low influenza intensity.
  • Display of data will be updated on a monthly basis during the interseason period (weeks 21-39).

DJ..we are now in week 39 so very likely weekly updates become available...We had another major bird-flu outbreak in NL yesterday-meaning 200,000 birds will get killed...H5N1 may be a growing risk...

End of part 1...(maybe later part 2 ???) 

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 27 2022 at 10:02am

part 2,

I will put non-pandemic items in the latest news section with the same name (as long as not being sabotaged...). 

[url]https://www.coronaheadsup.com/coronavirus/germany-chancellor-olaf-scholz-and-interior-minister-nancy-faeser-test-positive-for-covid/[/url] or https://www.coronaheadsup.com/coronavirus/germany-chancellor-olaf-scholz-and-interior-minister-nancy-faeser-test-positive-for-covid/ ;

German Chancellor Olaf Scholz has tested positive for COVID-19. Scholz’s office said he had gone into isolation and cancelled his public appointments for the week.

Germany’s Interior Minister Nancy Faeser has also tested positive for the first time since the start of the pandemic.

“Now Corona got me too, for the first time. The virus remains insidious. Everyone take care of yourselves this fall!”


DW.com report

DJ...I did not see reports of more cases after the UK royal funeral...so may have been limited ? 

[url]https://nltimes.nl/2022/09/27/new-covid-wave-may-begun-patient-total-new-infections-set-new-40-day-highs[/url] or https://nltimes.nl/2022/09/27/new-covid-wave-may-begun-patient-total-new-infections-set-new-40-day-highs

Officially diagnosed coronavirus infections have been rising for four weeks in the Netherlands. A high number of people testing positive at the GGD over the past seven days is one piece of evidence suggesting the start of a new coronavirus wave, warned public health institute RIVM. The report published on Tuesday showed the most infections since August 13, with figures from the hospitals showing the highest number of Covid-19 patients in care since August 18.

“This may be the start of the expected COVID fall wave. Vaccination and testing are very important in this phase to prevent the numbers from rising sharply,” the RIVM said in a statement.

DJ, see also (more correct) [url]https://www.rivm.nl/en/news/autumn-wave-of-COVID-19-may-be-starting-vaccination-and-testing-are-key[/url] or https://www.rivm.nl/en/news/autumn-wave-of-COVID-19-may-be-starting-vaccination-and-testing-are-key 

Most of Europe may be getting into another wave [url]https://www.thailandmedical.news/news/latest-sars-cov-2-bq-1-1-and-ba-2-3-20-variants-driving-exponential-daily-new-infections-and-hospitalizations-across-europe-with-high-incidences-of-ar[/url] or https://www.thailandmedical.news/news/latest-sars-cov-2-bq-1-1-and-ba-2-3-20-variants-driving-exponential-daily-new-infections-and-hospitalizations-across-europe-with-high-incidences-of-ar 


7 BA.2-like have been sequenced fast. 👏 And with some interesting results! 1 BJ.1 (BA.2.10.1.1) 2 BL.1 (BA.2.75.1.1) 1 BA.2.75.5 1 BA.2.75.2 2 BA.2.75.2/BA.5.2.1 recombinants Likely breakpoint at the spike between 23019 (S:F486S) and G24620T (S:A1020S). They do not have D1199N

-


A total of 177 randomly selected SARS-CoV-2 positive samples, collected between September 14th&Sept 20th 2022 at  testing facilities, 0/177(0%) indicated a BA.1-like, 6/177(3%) a BA.2-like and 171/177(97%) a BA.4/5-like variant. Thanks to  and GGD lab.

see how things develop further...

end of part 2

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 27 2022 at 10:28pm

DJ, 

-When you use a car to go somewhere nearby the means of transport may be 10x the weight of your body...using lots of fuel, space, causing enviromental damage...I personally take a bicycle...less then 1/10 of my weight...taking limited space, very low cost...in urban area's often faster (easy parking !)...

In this pandemic vaccines may stand for cars, masks for bikes...

YES-(New) vaccines may have done a great job in limiting disease - no they did not stop the pandemics. Masks may have (maybe) done more to "stop the spread"...

In traffic you have both cars and bikes...in a pandemic one may need both vaccines and Non Pharma Interventions...how to balance that should be part of a strategy...and I am missing a clear strategy here in NL, most of "the west". China has a clear "Zero CoViD" strategy-has a "strong government" able to enforce it...other countries are in between strategies and what they are able to do...

Maybe the biggest mistake in the present pandemic is NOT limiting air traffic to 5-10% from pre-pandemic level (would also fit climate plans). All kinds of virusses/variants are allowed to fly for free. We are importing variants/diseases from Brazil, Africa, China etc...are exporting our own diseases around the globe...

In Dutch "mopping the floor with the tap still open" (dweilen met de kraan open)...If vaccines would be sterilizing there could maybe some room for this "leaky strategy" but vaccines so far do NOT stop infection or spread-at best limit disease so far...however newer variants are a nightmare...

[url]https://en.wikipedia.org/wiki/Exponential_growth[/url] or https://en.wikipedia.org/wiki/Exponential_growth ; The growth of a bacterial colony is often used to illustrate it. One bacterium splits itself into two, each of which splits itself resulting in four, then eight, 16, 32, and so on. The amount of increase keeps increasing because it is proportional to the ever-increasing number of bacteria. Growth like this is observed in real-life activity or phenomena, such as the spread of virus infection, the growth of debt due to compound interest, and the spread of viral videos. In real cases, initial exponential growth often does not last forever, instead slowing down eventually due to upper limits caused by external factors and turning into logistic growth.

DJ..to put it (very) simple; exponential growth is doubling of something over time...(1-2-4-8-16-32-64-128 etc...). 

[url]https://en.wikipedia.org/wiki/Exponential_growth#Biology[/url] or https://en.wikipedia.org/wiki/Exponential_growth#Biology ;

  • The number of microorganisms in a culture will increase exponentially until an essential nutrient is exhausted, so there is no more of that nutrient for more organisms to grow. Typically the first organism splits into two daughter organisms, who then each split to form four, who split to form eight, and so on. Because exponential growth indicates constant growth rate, it is frequently assumed that exponentially growing cells are at a steady-state. However, cells can grow exponentially at a constant rate while remodeling their metabolism and gene expression.[3]
  • A virus (for example COVID-19, or smallpox) typically will spread exponentially at first, if no artificial immunization is available. Each infected person can infect multiple new people.

DJ..one basic -WRONG !!!- idea was once you did get CoViD (like the idea is for SARS-1/2003) you would have long term immunity...It is unclear how many billion (non)human CoViD infections there have allready been-but CoViD developed into evading immunity on a major scale...So previous infections may NOT stop the exponential growth trend either much or long term...

Vaccines may have done a great job (most vaccines worldwide were not m(essenger)RNA but "old(er) style" made in China, India, Russia often using an adeno-virus "bringing the CoViD message" resulting in (better) immunity/limiting damage after a CoViD infection...However new variants (now all named "Omicron" may be over a thousend by now !) are able to work around vaccine immunity...

Since the high number of CoViD-infections do damage immunity (a.o.) "humans-as a species" may have less immunity against all kind of other diseases...(exponentiol growth in width not in depth). 

Compared to the Spanish Flu (killing between 20 and a 100 million; 2-5% of the global population. I go for the wide timeline of 1917-1923.) were people developed immunity against reinfection SARS-2/CoViD-19 is a much larger problem...

A virus is "on the edge of live" because it needs a host for reproduction...There are close to 8 billion human hosts...CoViD has been detected in up to a hundred other species...so...what is stopping exponential growth for CoViD ? DJ-Vaccines, NPI may be buying time...but it is a very big problem...

-[url]https://www.thailandmedical.news/news/study-validates-previous-findings-that-sars-cov-2-reinfections-are-now-occurring-at-shorter-intervals--current-cdc-and-ecdc-reinfection-definitions-ar[/url] or https://www.thailandmedical.news/news/study-validates-previous-findings-that-sars-cov-2-reinfections-are-now-occurring-at-shorter-intervals--current-cdc-and-ecdc-reinfection-definitions-ar e obsolete !

Lots of links in the article...One major remark [url]https://www.thailandmedical.news/news/breaking-long-covid-is-a-misnomer-the-conditions-are-being-caused-by-viral-persistence-and-viral-peptides-similar-to-retrotransposons-and-introns[/url] or https://www.thailandmedical.news/news/breaking-long-covid-is-a-misnomer-the-conditions-are-being-caused-by-viral-persistence-and-viral-peptides-similar-to-retrotransposons-and-introns in many cases once the virus is in it may stay...So reinfection could mean another variant on top of variants allready in the host...

The virus -often hiding- may keep doing damage...may even renew a start in spread. Sometimes a "re-infection" may mean the "old" virus is "out of hiding"...

For that matter-in my non expert view ( I know something of history, limited of biology...NOT a medical person...) 

-Long CoViD may be related to damage done by a CoViD infection...with some luck however the virus is gone...

-Chronic CoViD may be long term infection WITH the virus (variants-could be more then one...) still in the body...

DJ-Non Pandemic in latest news...refugees spreading infection, water/flooding linked diseases DO have a link with the pandemic. Economies falling apart means less money/capacity for healthcare (here in NL in some sectors 10%+ on sick leave...) Avian Flu-H5N1 in my opinion is "a very major risk"...2022 is a very bad year for "bird flu" worldwide...

African Swine Fever (ASF)-pandemic in pigs (2018-20) was before CoViD...Bird Flu now getting this big...may have some links with CoViD (missed/masked in pigs, birds ???)...

"One Health" does not exclude humans but has a more holistic view...we are all part of nature...I am NOT a statistician...but ASF NOT being linked to CoViD how likely is that ? 

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 28 2022 at 3:03am

part 2, 

Lots of non-pandemic (directly) news...trying to just follow that...

[url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table with simply very limited numbers/reporting the statistics are at best giving some indication; 

Global cases would be -14%...Japan a.o. had very high numbers...So Japan -27% on cases, South Korea -42% makes some sense...from very high numbers...US cases -43% however does NOT make sense...did they stop reporting US cases ? 

Europe cases +6%, with Germany cases +42%...NL +39%...France still +27% while they already were in high numbers...Oceania +8%, Australia +11% for cases...

[url]https://www.thailandmedical.news/news/spike-346-mutations-emerging-in-many-new-omicron-variants-and-sub-lineages-is-helping-sars-cov-2-to-escape-neutralization-by-all-known-antibodies[/url] or https://www.thailandmedical.news/news/spike-346-mutations-emerging-in-many-new-omicron-variants-and-sub-lineages-is-helping-sars-cov-2-to-escape-neutralization-by-all-known-antibodies again development in the WRONG direction !

-[url]https://forum.arctic-sea-ice.net/index.php/topic,3863.0.html[/url] or https://forum.arctic-sea-ice.net/index.php/topic,3863.0.html a discussion on if the Arctic melting season is over or not...Like pandemics you may need lots of data to reach a conclusion...[url]https://www.wormsandgermsblog.com/2022/09/articles/animals/cats/monkeypox-guidance-for-vets/[/url] or https://www.wormsandgermsblog.com/2022/09/articles/animals/cats/monkeypox-guidance-for-vets/ we may simply not have enough info...

[url]https://www.wormsandgermsblog.com/2022/09/articles/animals/birds/avian-influenza-response-approaches-does-one-size-really-fit-all/[/url] or https://www.wormsandgermsblog.com/2022/09/articles/animals/birds/avian-influenza-response-approaches-does-one-size-really-fit-all/ what are the risks of Avian Flu...

Another major concern I have with any strict policy is driving things underground. If bird owners know a positive test means all their birds will be killed, they’re more likely to try to ride out a problem and not get testing done. That means we lose valuable information, don’t get a chance to respond to help contain the issue, and we can miss the ability to manage disease properly if it’s something other than flu. I can absolutely see non-commercial bird owners avoiding testing if stories of mandatory depopulation of birds like theirs increase. We need to know the extent of the spread of this virus so we can take other steps to control it, and driving things underground doesn’t help.

Is there room for a "balanced approach"? [url]https://thebulletin.org/2022/09/is-the-next-pandemic-brewing-on-the-netherlands-poultry-farms/[/url] or https://thebulletin.org/2022/09/is-the-next-pandemic-brewing-on-the-netherlands-poultry-farms/ (good article-hope to find time for more on it later on...) DJ-If you want to put public health on top-relate it to possible very major risks of High Pathogenic Avian Influenza (HPAI) often-not only-H5N1 (other H5/H7 types a.o. also risks) spreading into humans there may be NO room....

DJ-I am not an expert but if I had to make a decission we would STOP animal farms NOW ! High populated area's may be most at risk...NL-south part-is almost a 10 million+ city...NW Europe-depending on definition is 60-100 million people in lots of urban area's...From millions of minks, (most of them now killed)  chicken, pigs to cows this pandemic should learn us this is asking for disaster...

We may be just a few steps away from a much worse pandemic...STOP THE SPREAD ! STOP creating lots of other diseases in overcrowded farms ! There are a few other area's in the world combining millions of people with millions of animals...China is being blamed for many outbreaks...but it simply is NOT only China...In Africa one has mega cities housing millions-often poor...combining it with lots of animals, poor hygiene...

A next pandemic may already have started-we only will learn it in a few weeks, month...Sequencing, testing is out of capacity...

End of part 2

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 28 2022 at 11:23pm

DJ, 

Let me start with a non-pandemic item, music related;[url]https://www.gelderlander.nl/arnhem/amerikaanse-zangeres-moet-arnhems-hotel-verlaten-om-discussie-over-steak-je-zet-toch-geen-75-jarige-op-straat-br~a9cbdb50/[/url] or https://www.gelderlander.nl/arnhem/amerikaanse-zangeres-moet-arnhems-hotel-verlaten-om-discussie-over-steak-je-zet-toch-geen-75-jarige-op-straat-br~a9cbdb50/ one of my favorite old time singers Melanie (now 75) and her son were kicked out of the Arnhem Centre "Bastion Hotel" in a fight over a steak....insanity rules...

[url]https://www.youtube.com/watch?v=PoyyZEaDUyU[/url] or https://www.youtube.com/watch?v=PoyyZEaDUyU "Beautifull People"...1971 somehow [url]https://en.wikipedia.org/wiki/Melanie_(singer)[/url] or https://en.wikipedia.org/wiki/Melanie_(singer) somehow was in my town Arnhem several times...never expected to end up kicked out of a local hotel...[url]https://twitter.com/melaniesafka[/url] or https://twitter.com/melaniesafka and [url]https://www.facebook.com/melanie.safka.5[/url] or https://www.facebook.com/melanie.safka.5 ...crazy !

-There is some talk of a Polar Vortex [url]https://www.severe-weather.eu/global-weather/polar-vortex-cooling-forecast-winter-2022-2023-influence-united-states-europe-fa/[/url] or https://www.severe-weather.eu/global-weather/polar-vortex-cooling-forecast-winter-2022-2023-influence-united-states-europe-fa/ wich could bring cold weather to the US, Europe "later on"...in the middle of an energy crisis (for wich a growing number of people point to biden...) in "the west"...It will increase social unrest...Mass protests, riots and pandemics are NOT a good combination...More on-what looks like US attacks on European-Russia pipelines in non pandemic latest news...insanity rules...

[url]https://www.coronaheadsup.com/europe/europe-another-record-breaking-winter-wave-predicted/[/url] or https://www.coronaheadsup.com/europe/europe-another-record-breaking-winter-wave-predicted/ ;(Ourworldindata)

These European Covid-19 infection charts do NOT look good – almost every country in Europe has a higher Covid case level now than before the huge Omicron winter wave of 2021.

We compared Covid  cases numbers for 27th September 2021 and 27th September 2022 across a few European countries to see how they were faring before the new winter wave sets in.

In almost every European country we looked at, Covid case numbers are far above those on the same date the year last year, and that is despite a dramatic reduction in testing across the continent.

 

Germany currently has nearly SEVEN times as many Covid cases as on the equivalent day last year,

Italy has nearly seven times as many Covid cases as on the equivalent day last year,

France has about seven times as many Covid cases as on the equivalent day last year,

The entire European Union has around three times as many Covid cases as on the equivalent day last year,

Rising Covid case numbers are already feeding through to increased hospitalizations in France and Germany. Hospitalizations in both countries are already running at about twice the level of 27th September 2021.

Our prediction for the European winter wave of 2022: 
Due to a lack of simple, cheap and effective Covid mitigations being implemented across Europe, we predict another record-breaking year for the pandemic on the continent.

If you are travelling over the winter holidays, please take every precaution you can to prevent infection or reinfection.

DJ, [url]https://nltimes.nl/2022/09/28/rivm-new-covid-restrictions-despite-rising-cases-nl-unprepared-sharp-increase[/url] or https://nltimes.nl/2022/09/28/rivm-new-covid-restrictions-despite-rising-cases-nl-unprepared-sharp-increase ;

It is not yet necessary to take extra measures against the spread of the coronavirus, Jaap van Dissel of the public health institute RIVM said in a briefing to parliament on Wednesday. The basic measures like regular hand washing and going into isolation if you test positive should suffice, he said. At the same time, the Cabinet's advisory group, the Social Impact Team (MIT), cautioned that the Netherlands is not ready to handle a severe increase in infections and Covid-19 hospitalizations.

According to Van Dissel, the government's thermometer to monitor the pandemic's status is currently at its lowest level. That means the pressure on healthcare and society is limited and likely to remain so for the time being.


Van Dissel stressed that the Netherlands is not yet in a stable “endemic phase” of this pandemic. There is still a lot of uncertainty about the emergence of new variants, how much immunity has been built against the coronavirus, and how long that will last.

On Tuesday, the RIVM reported that the expected autumn wave of coronavirus infections may have started in the Netherlands. Although there were fewer than 400 patients with Covid-19 in Dutch hospitals on September 9, that figure rose significantly in subsequent days. Just in the past week, the number of patients jumped by more than a third to 631. The percentage of those patients needing intensive care remained low at 35, though that figure also rose by ten in a week. Hospitals admitted 34% more patients with Covid-19 on average over the last seven days compared to the week before. That includes 117 new hospital admissions on Tuesday, the most in nearly two months.


The surging hospital data coincides with a rise in coronavirus particulate matter found in sewer water, the rising basic reproduction (R) value that models the spread of the coronavirus, and the number of infections diagnosed by a healthcare facility. The latter jumped towards a seven-week high, rising by 39 percent, far outpacing the 27 percent increase in testing at the GGD.

The country is not ready for another rapid coronavirus outbreak

Jolande Sap, the chair of the MIT, warned that the Netherlands has not adequately prepared for the continuation of a sharp increase in infections over the next six months. At the same briefing Van Dissel attended, Sap said that it "cannot be ruled out that those scenarios will happen."

Sap said that the government should continue to keep coronavirus access passes as a legal option to impose on the public if the situation spirals out of control. In the past, the access passes were distributed based on vaccination status, prior infections, and test status. The passes were used to enter a variety of locations, like bars, restaurants, museums, and events, depending on the state of the coronavirus pandemic in the Netherlands.

She also said that the government was not placing enough consideration on people who may be impacted by a tightening of measures, such as young people, and people who have had difficulty becoming a part of the workforce. She also said that politicians need to better debate the ethics of the Cabinet's decision-making, "such as the trade-off between saving lives immediately, and protecting long-term quality of life."

Unenthusiastic vaccination turnout; Face masks should return, experts say

Figures from the RIVM show that people who got their Covid-19 vaccinations and a booster shot are 47 percent less likely to require hospitalization than people who skipped the booster shot and just got the repeat shot. After the repeat shot, people are 22 percent less likely to end up in the hospital with a coronavirus infection. The chance of needing intensive care is also smaller.

Given the increase in infections, especially among people over the age of 70, it is a “good time to start vaccinating again,” Van Dissel said. The Netherlands started the latest round of coronavirus vaccinations, using updated Pfizer and Moderna vaccines that offer better protection against the Omnicron variant, last week.

Turnout for the new vaccination round has been low, with fewer than 16 percent of people over 80 receiving a jab, though some may not be able to get a new vaccination because of a recent infection. “You see that people are less interested in a repeat jab when the extra shot is sensible,” said virologist Bert Niesters to the Telegraaf. “It is especially so if you have an underlying condition or you are older.”

He said it is clear that the coronavirus is not gone, particularly since the current Cabinet has not recommended any further measures to slow the new wave of infections. “With the current increasing figures, I would think it would be wise if there were a new emphasis on wearing face masks in busy places, such as in supermarkets, public transport, and in line at Schiphol,” Niesters told the newspaper.

“This is already normal in other countries such as Germany. Together with good hand hygiene, this helps to limit the spread.”

Radboudumc internist and infections expert Chantal Bleeker-Rover agreed. "Wearing a mask over the mouth and nose is much more effective than measures, such as extra cleaning, placement of splash screens, and creating walking routes," she told Omroep Gelderland. "If people want to protect themselves, such a mask is much more effective than those other things.

On Dutch twitter;








I'm not sure what goes into these calculations here, but the BQ.1(.1) growth advantage is visible globally. And unless these outbreaks were preferentially sequenced because they are BQ.1(.1) - they should only increase parameter noisiness, not bias the growth advantage estimate.

DJ [url]https://twitter.com/BertMulderCWZ[/url] or https://twitter.com/BertMulderCWZ (in Dutch) a.o. there is shock and anger on the total stupidity of a non-functioning strategy...From ventilation (who will pay) to sticking to old vaccines (still in storage...) NL government is failing again...Political bla-bla with potential loss of lives this coming winter due to diseases that should have been stopped -for NL alone-maybe in the tens-of-thousends....

End of part 1....

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 29 2022 at 12:05am

part 2, 

[url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table European cases-bad statistics cases +8%...since lots of countries do not provide daily updates "statistics erode over non-reporting days"...[url]https://www.rivm.nl/coronavirus-covid-19/weekcijfers[/url] or https://www.rivm.nl/coronavirus-covid-19/weekcijfers september 27 had NL test result cases +39%...but they only report on tuesday and friday...so worldometer has NL cases now "only" at +16%...

Status of the latest #COVID19 Wave in #NorthEast #USA (MD, PA, DE, NY, MA, VT, CT, NJ, ME, NH, RI) Top circulating variants - BA.5.2.1, BA.4.6 (~14%), BA.5.2 Other: BF.7 (2.6%) BQ.1 (1.2%) BE.1.1 (1.7%) Closely watching hospitalizations.. Don't let your guard down! 15/n

DJ, In worldometers US cases -31% [url]https://public.tableau.com/app/profile/raj.rajnarayanan/viz/HospitalCapacity-USA/HospitalCapacity[/url] or https://public.tableau.com/app/profile/raj.rajnarayanan/viz/HospitalCapacity-USA/HospitalCapacity with several US states hospital capacity in use allready over 90%...(Roode Eylant/ (old Dutch name..) Rhode Island ) and 12 states 80% or more...

[url]https://www.coronaheadsup.com/health/treatment/remdesivir/preprint-mutated-sars-cov-2-variant-resistant-to-remdesivir/[/url] or https://www.coronaheadsup.com/health/treatment/remdesivir/preprint-mutated-sars-cov-2-variant-resistant-to-remdesivir/ ;

A new preprint study shows that two kidney transplant patients treated with immunosuppressive drugs, and who later had a lengthy COVID-19 infection, developed a version of the virus with a genetic change that made it resistant to the antiviral therapy remdesivir.

Our work emphasizes the potential risk of immune escape in immunocompromised hosts, a scenario in which novel spike mutations evade a suboptimal immune response and contribute to recrudescence of symptomatic infection. Equally concerning are recent reports in immunocompromised hosts highlighting the proclivity of SARS-CoV-2 to develop spike mutations conferring resistance to immunotherapeutics after treatment with monoclonal antibodies.

As remdesivir use has become widespread, and we show that mutations associated with remdesivir resistance arise in vivo, our work emphasizes the importance of augmented surveillance efforts to detect clinically significant mutations in immunocompromised patients. Potentially foreshadowing an “endgame” scenario for the COVID-19 pandemic, complex cases like the ones described in this report may presage the eventual need for more advanced molecular diagnostics at the onset of illness to guide therapeutic decisions. It is reasonable to assess for new mutations in patients with prolonged illness who experience persistent infection despite initial therapy.

Preprint: Remdesivir resistance in transplant recipients with persistent COVID-19

DJ [url]https://www.thailandmedical.news/news/with-the-debut-of-over-200-new-immune-evasive-omicron-variants-and-sub-lineages-expect-a-winter-of-dangerous-reinfections-and-coinfections[/url] or https://www.thailandmedical.news/news/with-the-debut-of-over-200-new-immune-evasive-omicron-variants-and-sub-lineages-expect-a-winter-of-dangerous-reinfections-and-coinfections  (TMN) a.o. a link [url]https://cov-spectrum.org/collections/24[/url] or https://cov-spectrum.org/collections/24 to 203 Omicron subvariants with evasive mutations...TMN again warning some new variants have "qualities" seen in SARS 1...[url]https://en.wikipedia.org/wiki/SARS-CoV-1#SARS[/url] or https://en.wikipedia.org/wiki/SARS-CoV-1#SARS

In the SARS outbreak of 2003, about 9% of patients with confirmed SARS-CoV-1 infection died.[14] The mortality rate was much higher for those over 60 years old, with mortality rates approaching 50% for this subset of patients.[14]

Of course the 2003-SARS-1-outbreak was limited...hospitals could provide a lot of HQ care....this winter hospitals may be without enough staff, energy, finance, medication...

The most important tool in any crisis is information...

However if governments, some "experts-for-sale" simply deny the problems (climate collapse, pandemics, risks of war) and only go for short term profits-based on greed and stupidity fighting for dominance...well then the only real answer has to be get other leaders in place....

TMN mentions shorter intervals in reinfections, likely lots more co-infections...DJ-Those co-infections may be outside CoViD...a CoViD-H5N1 flu coinfection could become a disaster...Of course global H5N1 is "out of control" in birds...but also detected infoxes...very likely in other mammals eating dead infected birds...Vaccines-even the newest-could become "less effective" soon...Still might offer some protection against severe disease...

But a "vaccination strategy" in wich vaccines do NOT stop spread of infection-only limits disease-needed a major Non Pharma Intervention strategy that has been totally missing "saving the economy"...A bit like sand bags in front of the front door during a hurricane bringing over 3 meter (12 feet !!!) waves...it is simply not enough !!!!

Somehow "experts" are unwilling to accept science not fitting their "world view"...Exponentials in climate change, pandemics can result in very major changes in a short time...

Maybe first steps are small; 1%, 2%, 4%...we can handle it...8%, 16% "economy first"...32%, 64%...collapse...in a society as complex as modern western ones small changes may allready cause major disruptions... "Just in time delivery" may see a proces getting destroyed when some aspects are "not in time"...

I think you have to put a pandemic against a background. The Spanish Flu did kill that many because of World War One...The coming CoViD winter wave-in combination with CoViD fatigue, bad info, governments unable to understand the crisis...it is a mega mix that can result in the worst human crisis since the middle ages plague in Europe (or the "discovery of the America's by Europeans killing up to 90% of the original American population..Massive slave trade-killing tens of millions of slaves either during transport (as cargo) or in the fields...Brazilian slaves were seen as short term investments..if they worked a few years the investment was "worthwile"...old slaves did cost money...I will not even start on breeding slaves...). 

End of part 2

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 29 2022 at 10:06pm

DJ, more then enough news...

Of course hurricanes -destroying homes and hospitals- most likely will worsen a pandemic. Extreme weather is increasing worldwide...in many ways it can be linked to increasing pandemic risks...Wars, climate change do result in lots of refugees-often in not such good health...however most of global travel is NOT related (yet) to refugees...but vacation, trade...Airtravel has been a main factor in spreading CoViD, worsening climate "change"-in fact climate collapse...

If we seriously wanted to deal with pandemics, climate collapse airtravel would be 5-10% of what it was in 2019....in most places air travel is at pre-pandemic level "saving the economy/profits..."

Some did make claims the "pandemic is over"; 

A pandemic is an epidemic occurring on a scale that crosses international boundaries, usually affecting people on a worldwide scale.[13] A disease or condition is not a pandemic merely because it is widespread or kills many people; it must also be infectious. For instance, cancer is responsible for many deaths but is not considered a pandemic because the disease is not contagious—i.e. easily transmittable—and not even simply infectious.[14]

In 2009, the World Health Organization (WHO) dropped the words "with enormous numbers of deaths and illness" from their definition.[15] In 2008, it also dropped the requirement of an "influenza pandemic" to be a new sub-type with a simple reassortant virus, meaning that many seasonal flu viruses now could be classified as pandemic influenza.[16]

[url]https://en.wikipedia.org/wiki/Pandemic#Stages[/url] or https://en.wikipedia.org/wiki/Pandemic#Stages ; Stage 6-pandemic in progress, sustained (spread) in more then one WHO region. There is also a "post peak" phase...but "post peak" does not mean you are out of the pandemic...there could be another peak...higher even then the previous one...

So -do we see a stop of CoViD spread in ANY WHO region ???? On what bases "a responsible person" could make a claim the pandemic is over ? "Endemic";

In epidemiology, an infection is said to be endemic (from the Greek ἐνen, "in, within" and δῆμοςdemos, "people") in a population when that infection is constantly maintained at a baseline level in a geographic area without external inputs.[1] For example, chickenpox is endemic (steady state) in the United Kingdom, but malaria is not. Every year, there are a few cases of malaria reported in the UK, but these do not lead to sustained transmission in the population due to the lack of a suitable vector (mosquitoes of the genus Anopheles). While it might be common to say that AIDS is "endemic" in some countries, meaning found in an area, this is a use of the word in its etymological, rather than epidemiological or ecological, form.

For an infection that relies on person-to-person transmission, to be endemic, each person who becomes infected with the disease must pass it on to one other person on average. Assuming a completely susceptible population, that means that the basic reproduction number (R0) of the infection must equal one. In a population with some immune individuals, the basic reproduction number multiplied by the proportion of susceptible individuals in the population (S) must be one. This takes account of the probability of each individual to whom the disease may be transmitted being susceptible to it, effectively discounting the immune sector of the population. So, for a disease to be in an endemic steady state it is:

{\displaystyle R_{0}\times S=1}{\displaystyle R_{0}\times S=1}

In this way, the infection neither dies out nor does the number of infected people increase exponentially but the infection is said to be in an endemic steady state. An infection that starts as an epidemic will eventually either die out (with the possibility of it resurging in a theoretically predictable cyclical manner) or reach the endemic steady state, depending on a number of factors, including the virulence of the disease and its mode of transmission.

If a disease is in an endemic steady state in a population, the relation above allows us to estimate the R0 (an important parameter) of a particular infection. This in turn can be fed into a mathematical model for the epidemic. Based on the reproduction number, we can define the epidemic waves, such as the first wave, second wave, etc. for COVID-19 in different regions and countries.[2]

[url]https://en.wikipedia.org/wiki/Endemic_phase_of_COVID-19#Medical_view[/url] or https://en.wikipedia.org/wiki/Endemic_phase_of_COVID-19#Medical_view ;

On 14 April 2022, the World Health Organization said that COVID-19 is far from becoming an endemic disease and could still trigger large outbreaks around the globe.[1]

In June 2022, an article in Human Genomics said that the pandemic was "still raging" but "now is the time to explore the transition from the pandemic to the endemic phase. The latter will require worldwide vigilance and cooperation, especially in emerging countries", and suggested that developed countries should assist in boosting vaccination rates worldwide.[2]

and [url]https://en.wikipedia.org/wiki/Endemic_phase_of_COVID-19#Analysis[/url] or https://en.wikipedia.org/wiki/Endemic_phase_of_COVID-19#Analysis ;

A 2021 article in The Lancet called restrictions being lifted in the United Kingdom "dangerous and immature" and expressed concern that mass infection could lead to vaccine resistance and would impact young people, children and health services.[75] In The BMJ in February 2022, several health policy and public health experts criticised the British government's "living with COVID" plan, suggesting the end of free COVID-19 testing could exacerbate health inequality, and suggesting the plan did not account for required resources for localised contact tracing and hospital capacity.[76]

Elizabeth Stokoe and colleagues wrote that the phrase "living with COVID-19" is a cliché that has two opposed, disputed meanings. On the one hand it can mean simply returning to pre-pandemic living; on the other it can mean that life now must incorporate public health mitigation measures to reduce the impact of the disease. In the United Kingdom, the phrase had enjoyed wide currency among politicians and the popular media, particular in the later, post-2021, phases of the pandemic.[77]

DJ...Like the IPCC (International Panel on Climate Change) the WHO is a political organization...while both groups should put science-not profits-first..."living with the virus" made this pandemic almost impossible to control by now....[url]https://en.wikipedia.org/wiki/Variant_of_concern#Criteria[/url] or https://en.wikipedia.org/wiki/Variant_of_concern#Criteria ...the refusal to give new names to several variants-now all called "Omicron" is anti-science....

Governments denying major risks for the human species are endangering human live...They are not "just" failing...but when you know the risks, know how to limit those risks but rather go for profit governments may be pushing for genocide by pandemics, climate collapse...

False claims "the pandemic is over" by people in a high position is criminal...it is like claiming the house is safe when it is burning out of control...Telling a blind person it is safe to cross the street when it is not...Governments, health agencies have a job making as best as possible risk assesments...inform the public...

Hurricane warnings save lives...knowing the risks and not warning is killing people...millions of them...and that is totally unacceptable !

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 29 2022 at 11:17pm

DJ,

part 2-a look at [url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table "post pandemic" statistics....with poor reporting, at best as indication...however lots of extra info will give a more realistic view...

Global cases now at -4%...Europe cases +10%...winterwave did start here...Oceania cases +65%, deaths +2% (at the moment...). There are 66 countries reporting an increase of cases...Germany, Italy 50%+  Chile, Guatamala, Ghana all +46% ....[url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time UK self reporting numbers going up -over 2.1 million reporting symptoms....

There are lots of statistics-the Our World In Data-jungle....but what is needed is good testing and good reporting...sequencing may tell us more on what variants are spreading...however the picture I get is people may be infected by more then one variant...

[url]https://www.thailandmedical.news/news/breaking-university-of-queensland-study-discovers-that-sars-cov-2-actually-attacks-the-dna-of-heart-cells[/url] or https://www.thailandmedical.news/news/breaking-university-of-queensland-study-discovers-that-sars-cov-2-actually-attacks-the-dna-of-heart-cells link to [url]https://onlinelibrary.wiley.com/doi/10.1111/imm.13577[/url] or https://onlinelibrary.wiley.com/doi/10.1111/imm.13577 ;

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to present with pulmonary and extra-pulmonary organ complications. In comparison with the 2009 pandemic (pH1N1), SARS-CoV-2 infection is likely to lead to more severe disease, with multi-organ effects, including cardiovascular disease. 

SARS-CoV-2 has been associated with acute and long-term cardiovascular disease, but the molecular changes that govern this remain unknown. In this study, we investigated the host transcriptome landscape of cardiac tissues collected at rapid autopsy from seven SARS-CoV-2, two pH1N1, and six control patients using targeted spatial transcriptomics approaches. 


Although SARS-CoV-2 was not detected in cardiac tissue, host transcriptomics showed upregulation of genes associated with DNA damage and repair, heat shock, and M1-like macrophage infiltration in the cardiac tissues of COVID-19 patients. 


The DNA damage present in the SARS-CoV-2 patient samples, were further confirmed by γ-H2Ax immunohistochemistry. In comparison, pH1N1 showed upregulation of interferon-stimulated genes, in particular interferon and complement pathways, when compared with COVID-19 patients. 


These data demonstrate the emergence of distinct transcriptomic profiles in cardiac tissues of SARS-CoV-2 and pH1N1 influenza infection supporting the need for a greater understanding of the effects on extra-pulmonary organs, including the cardiovascular system of COVID-19 patients, to delineate the immunopathobiology of SARS-CoV-2 infection, and long term impact on health.

DJ...in short; it looks like CoViD is damaging hearth(muscle) DNA....

There is an increase of excess deaths-[url]https://www.euromomo.eu/graphs-and-maps/[/url] or https://www.euromomo.eu/graphs-and-maps/ above "normal" for all ages...But also depending on deaths being reported...What is defined as "a CoViD-death" -often as far as I know-the criteria is testing positive for CoViD and death-(from CoViD symptoms) within 4 weeks...Car accidents, wars, killing people that tested + for CoViD are not supposed to be included...however CoViD does do a lot of damage all over the body-long term...So what is a good definition for "death from CoViD" ? 

Does it matter ? I think the main point is -even with a strict definition- CoViD killing more people then -for example-the flu...It is-in that way-a serious risk. On top of that lots of long term health issues...[url]https://www.dutchnews.nl/news/2022/09/ministers-plan-e15000-payout-to-health-workers-with-long-covid/[/url] or https://www.dutchnews.nl/news/2022/09/ministers-plan-e15000-payout-to-health-workers-with-long-covid/ ;

Ministers want to give a ‘no strings’ €15,000 pay out to healthcare workers who developed coronavirus during the early stages of the pandemic and are now dealing with the impact of Long Covid. The pay out is not meant to be seen as damages, or some form of invalidity benefit, but is a ‘recognition of the suffering’ nurses and other healthcare staff have experienced, care minister Conny Helder told MPs on Thursday.
-

The two largest Dutch trade unions have threatened to take legal action against the government unless it offers compensation to healthcare workers suffering from long covid. They have welcomed news of the payout, but say it may be too little too late. The FNV and CNV say the government has failed to address the needs of some 5,500 frontline healthcare workers who are still suffering the effects of coronavirus infections in the early waves of the pandemic. According to the unemployment agency UWV, some 600 healthcare workers have been declared unfit for work due to long covid symptoms. A further 1,000 have been on sick leave for two years, and now risk losing their jobs. The unions say that government guidelines for protective equipment and quarantine violated World Health Organisation standards, allowing hundreds of healthcare workers to become infected

DJ...the pandemic is NOT over...CoViD is still a very serious health risk...with more then 3 million new cases being reported...Global CoViD deaths being rported (worldometers) number dropped from +10,000 last week to +8,000 last 7 days...That pattern indicates the effect of the last wave of CoViD on deaths may be decreasing...but again CoViD death is not well defined...reporting/testing is "poor"...numbers only may give some indication at best...

Thailand Medical News on its site -top bar- warning; Daily CoViD-19 infections, Hospitalizations and deaths rising in UK and elsewhere in Europe...Worldometers on deaths in some European countries ;

Denmark +42% ( last week 31, last 7 days 44 on a population of 5,8 million, 8 per million of the population)

Poland +32% ( last week 96, these last 7 days 127...population 37,7 million 3 per million of the population)

Germany +11%, France +7%...UK simply not reporting in these numbers...

-Another issue [url]https://www.thailandmedical.news/news/breaking-researchers-warn-that-sars-cov-2-could-also-infect-aquatic-mammals-such-as-dolphins-and-whales-creating-new-viral-reservoirs[/url] or https://www.thailandmedical.news/news/breaking-researchers-warn-that-sars-cov-2-could-also-infect-aquatic-mammals-such-as-dolphins-and-whales-creating-new-viral-reservoirs link [url]https://www.mdpi.com/2076-0817/11/10/1096[/url] or https://www.mdpi.com/2076-0817/11/10/1096 ;

Abstract

Due to marine mammals’ demonstrated susceptibility to SARS-CoV-2, based upon the homology level of their angiotensin-converting enzyme 2 (ACE2) viral receptor with the human one, alongside the global SARS-CoV-2 occurrence and fecal contamination of the river and marine ecosystems, SARS-CoV-2 infection may be plausibly expected to occur also in cetaceans, with special emphasis on inshore species like bottlenose dolphins (Tursiops truncatus). 

Moreover, based on immune and inflammatory responses to SARS-CoV-2 infection in humans, macrophages could also play an important role in antiviral defense mechanisms. In order to provide a more in-depth insight into SARS-CoV-2 susceptibility in marine mammals, we evaluated the presence of SARS-CoV-2 and the expression of ACE2 and the pan-macrophage marker CD68. Aliquots of tissue samples, belonging to cetaceans stranded along the Italian coastline during 2020-2021, were collected for SARS-CoV-2 analysis by real-time PCR (RT-PCRT) (N = 43) and Immunohistochemistry (IHC) (N = 59); thirty-two aliquots of pulmonary tissue sample (N = 17 Tursiops truncatus, N = 15 Stenella coeruleoalba) available at the Mediterranean Marine Mammal Tissue Bank (MMMTB) of the University of Padua (Legnaro, Padua, Italy) were analyzed to investigate ACE2 expression by IHC. 

In addition, ACE2 and CD68 were also investigated by Double-Labeling Immunofluorescence (IF) Confocal Laser Microscopy. 

No SARS-CoV-2 positivity was found in samples analyzed for the survey while ACE2 protein was detected in the lower respiratory tract albeit heterogeneously for age, gender/sex, and species, suggesting that ACE2 expression can vary between different lung regions and among individuals. Finally, double IF analysis showed elevated colocalization of ACE2 and CD68 in macrophages only when an evident inflammatory reaction was present, such as in human SARS-CoV-2 infection.

DJ...basic story; sea mammals have ACE-2 receptors able to get infected with CoViD-19 -however so far no CoViD-19 infection was detected in this study...

There are more "receptors" then ACE-2 able to get infected by CoViD-virus...Most people do not have much contacts with other species beside pets...Cats may be more vulnerable then dogs for catching CoViD...but even cats seem not be good in spreading CoViD....Minks may be the most-known-problematic animal for CoViD; easy catching AND spreading it...rats, mice (etc) may be more an unknown risk...

DJ-One possible bad scenario is that we may find no major problems in mice, rats etc...untill there is a new variant able to infect & spread high speed...via urine/dropping also possibly infecting other species, pets...[url]https://www.wormsandgermsblog.com/[/url] or https://www.wormsandgermsblog.com/ and lots of other institutions trying to do the best they can to monitor CoViD-risks in non-human hosts...

-Exponential growth..."explosion" of disease may show in increase of CoViD cases...Is also seen in decrease of immune protection after CoViD infection...resulting in an increase of all kinds of other (infectious) diseases. But it may also show in the number of (sub) variants of CoViD...Omicron now over 1,000 subvariants ? 

Another "exponential" aspect is spread outside the almost 8 billion humans...there are trillions of other animals on this planet...

So-if we would like to see an end to the pandemic-the last thing one wants is massive spread of CoViD in non-human hosts...Even if spread-for now-would be limited-it is a further risk....

[url]https://outbreak.info/situation-reports[/url] or https://outbreak.info/situation-reports showing 625 known/reported Omicron subvariants...

DJ-the picture I more and more get on this ongoing pandemic is "depressing"...."out of control"...a potential very major healthproblem able to kill millions of people in the coming years..

There are ways to stop/limit this; from (better) vaccines, masks to limiting travel (since virusses travel-for-free !) we are not doing enough to get out of this crisis...

End of part 2

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 30 2022 at 12:15am

part 3...twitter...posting from twitter is problematic...

My, oh, my, what's this? #SARS2 spiking in Massachusetts wastewater again. Hopefully next week Biobot will release all regions data, not only for the Northeast.

-

Now, this divergence is just bizarre. Is there some new variant in the Northeast that hasn't reach other parts of the US? Is it BarbeQue.1.1 time already?

-








Replying to 
This is the gentle increase that corresponded to the starting of schools (I don't know why other regions didn't have that). The new spike is what's unusual. I hear that lots of people/kids are sick with stuff that test negative on rapid tests. No idea what that's about 🤷🏻‍♀️

DJ...US cases -27% deaths -25%...reporting/testing may be one problem...there will be regional differences...Floriada, South Carolina may be dealing with "Ian"/stormdamage...

Is there also a variant spreading (a.o.) in the US that is escaping from testing ????

[url]https://public.tableau.com/app/profile/raj.rajnarayanan/viz/USAVariantDB/VariantDashboard[/url] or https://public.tableau.com/app/profile/raj.rajnarayanan/viz/USAVariantDB/VariantDashboard ; a mega-mix of sub-variants...

#COVID19 #VariantDashboard - #UnitedStates  TOP lineages (15-DAY TRENDS): 21.90%  BA.5.2.1 12.89%  BA.5.2 11.13%  BA.5.1 10.84%  BA.4.6 3.36%   BF.10 3.25%   BA.5.6 3.04%   BA.5.5 3.01%   BA.5 2.11%   BA.5.2.9

for the US-last 15 days...but again-if people test-do not get a + even with symptoms...sequencing may miss variants...








- We’re now seeing multi-system inflammatory syndrome in newly born INFANTS. SARS2 never attenuated. It never became mild. It still has a Sag, MHCI downreg, immune evasion/disruption/destruction, & viral persistence. It is not compatible with human physiology. Wear NIOSH PPE.

-

Around 16 million working-age Americans have long Covid today. 2 to 4 million are out of work due to long Covid. Annual cost of those lost wages alone is $170 billion a year (up to $230 billion).

link [url]https://www.brookings.edu/research/new-data-shows-long-covid-is-keeping-as-many-as-4-million-people-out-of-work/[/url] or https://www.brookings.edu/research/new-data-shows-long-covid-is-keeping-as-many-as-4-million-people-out-of-work/ DJ-of course also a lot of human suffering...depression, PTSD, etc on top of other health issues...

[url]https://www.medscape.com/viewarticle/981583[/url] or https://www.medscape.com/viewarticle/981583 ;DJ, For the US long/chronic CoViD costs could run into trillions...worldwide simply  unimaginable...Outcome of "saving the economy" ...it is destroying the economy !!!








Man who says he will die if covid protections are lifted dies of covid after covid protections are lifted What’s wrong with us?

Link;[url]https://www.cbc.ca/news/canada/thunder-bay/immunocompromised-death-covid-19-1.6597716[/url] or https://www.cbc.ca/news/canada/thunder-bay/immunocompromised-death-covid-19-1.6597716 ;

An immunocompromised man in Thunder Bay, Ont., who feared the consequences of relaxed public health measures died last month after testing positive for COVID-19.

Joe Lunn, a heart transplant recipient, told CBC News in March that he was worried about the Ontario government's decision to do away with vaccine certificates in public places.

He had also expressed concerns about its plans to end mask mandates, saying he felt safer in public when others were also taking precautions against spreading the virus. 

"I have fought too hard to stay alive to give up because you feel inconvenienced by a four-by-four inch cloth," he said at the time.

DJ...is this murder ? Is not stopping CoViD, climate collapse genocide ? If not-why not ? 








Covid hospitalisations on the up again, not just in England, but in several Western European countries...


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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 30 2022 at 10:54pm

DJ, part 1 (yesterday part 3 did proof the twitter problem...) 

October 1...

"This is exactly what the Security Council was made to do. Defend sovereignty, protect territorial integrity, promote peace and security," said US ambassador to the United Nations, Linda Thomas-Greenfield, adding "The United Nations was built on an idea that never again would one country be allowed to take another's territory by force."

Memory loss, amnesia, may be linked to long CoViD...

[url]https://nltimes.nl/2022/09/30/ministers-call-171-inflation-rate-terrible-extreme[/url] or https://nltimes.nl/2022/09/30/ministers-call-171-inflation-rate-terrible-extreme ;

Statistics Netherlands’ announcement that inflation was 17.1 percent in September, according to the European harmonized method, hit the Cabinet hard. Various Ministers commented, calling the inflation rate terrible and pointing out that the government is working on softening the blow.

“It is terrible,” said Finance Minister Sigrid Kaag, NOS reports. “It’s really extremely high, also in the countries around us.” She pointed out that the Cabinet already announced a 17 billion euros package to boost purchasing power next year and is working on the energy price cap for consumers.

DJ...creating, "printing" more money only worsens inflation...

[url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table as indication only; global cases at -3%, Europe cases +14%, Africa +0,5%...(Oceania cases depend on Australia reporting them...-19% is a "false statistic"...Australia reporting cases once, twice a week...?) 

Some statistics per country/cases, Tunesia +87%, Austria +66%, Germany +60%, Italy +57%, NL +56%, Ghana +46%, Algeria +39%, Papua New Guinea +36%, Singapore, Denmark both +35%, Chile +34%, France, China (!) +33%, South Africa, Saudi Arabia, Libya all +25%, Bangladesh +16%, Brazil +9%, Israel , Croatia, Ethiopia, Iceland all +8%, Spain +5%, Taiwan +3%..

There are 76 countries reporting an increase of cases...Three countries reporting over 10,000 new cases per million of the population...Montserrat, Dominaca are small...Taiwan ( with 12,082 cases per million in the last 7 days) is a larger country...good healthcare, testing, reporting...39 more countries reported over 1,000 new cases per million...

In other words, three countries did report 1%+ of their population testing positive last week, 39 countries did find 0,1%+ of their population tested positive...[url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time UK cases going up..."incorrect statistics" in worldometers has UK cases -4%...

US cases in worldometers -26%...other (twitter) sources may signal the US has a variant escaping testing ?????

Of course with "politics" going for more war, hyperinflation, any basis for limiting this pandemic is missing...

[url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory a few countries had a last update september 22...a lot of them simply stopped reporting in august...

And this; [url]https://www.aconlabs.com/public-notice-of-counterfeitflowflex-covid-19-antigen-home-test-kits/[/url] or https://www.aconlabs.com/public-notice-of-counterfeitflowflex-covid-19-antigen-home-test-kits/ ;

ACON Laboratories, Inc., has become aware that counterfeit versions of its FDA-authorized Flowflex® COVID-19 Antigen Home Tests in the 1 Test/ kit box configuration marked as Lot# COV2010030 and COV2030016 are being illegally distributed in the United States through unauthorized distributors. These counterfeit tests have not been authorized, cleared, or approved by the FDA for distribution or use in the United States, but their packaging and components may very closely resemble authentic FDA-authorized Flowflex tests. 

Consumers should take precautions to avoid purchasing Flowflex in the 1 Test/ kit box configuration marked as Lot# COV2010030 and COV2030016, that was not distributed through an authorized distributor. ACON is currently not aware of any counterfeit tests in the 2 Test/ kit box and 5 Test/ kit box configurations. The performance of these counterfeit tests has not been adequately established and there is concern about the risk of inaccurate results when people use these unauthorized tests.

Flowflex tests from Lot# COV2010030 and COV2030016 purchased from ACON’s authorized distributors or retail partners listed on FlowflexCOVID.com are authentic and safe to use.

DJ...I have some of the test-kits here at home...In NL the print on the side is a bit different from the US...If fake-test are the problem-in some countries-at least there would not be variants escaping testing....








2 Brazilian HCWs contract #monkeypox, seemingly during a home care visit to a person later confirmed to have MPX. The report, in , underscores the importance of good infection control practices & the role fomites can play in transmission. https://wwwnc.cdc.gov/eid/article/28/12/22-1343_article

DJ...some indication MPX did increase spread after schools/workplaces reopened...simply not being reported...

How NOT to fight a pandemic !

End of part 1

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: September 30 2022 at 11:28pm

DJ, part 2,

Some US tweets;

And here's the divergence confirmed in new #COVID hospital admissions per regions. Compare Northeast Regions 1-3 with total US. HHS Region 1 is the only (first?) one up.

see also [url]https://twitter.com/x2IndSpeculator/status/1575999743117123584/photo/1[/url] or https://twitter.com/x2IndSpeculator/status/1575999743117123584/photo/1 (side arrow to photo 4) 

Replying to 
This graph is great at showing how we've been oddly flat, but clearly elevated, all summer. Just like the wastewater data shows. I honestly don't know what to make of this pattern - is this what "endemic" looks like? Is that our new baseline level between waves?

-

Replying to 
Similar happened in England. Endemic without NPIs or PIs means constant (re)infections; so permanently higher baseline level & waves muted. Then, authorities compare this level with the tops of the highest early waves (which btw have been followed by deep lows) & declare victory.

DJ... the US, UK, NL are run by political criminals...putting short term profits ("economy") above long term public health...If one looks at the bla-bla on climate collapse these "leaders" produce...NOT even limiting air travel, empty words...Again-the pandemic is the outcome of criminal politics...We can NOT get out of this worsening pandemic with the present "political clique"...not representing the people but an elite...

Some more on US-UK pandemic patterns;

Replying to 
England had a very different pattern from us - they had 3 distinct waves (BA1, BA2, and BA5), at fairly consistent intervals (3 months). With no periods of flatness - they kept going either up or down. It's the level of flatness we had here, going neither up nor down, that's odd.

-

Replying to 
That's true, they had more distinct waves, although those waves are more frequent but smaller in amplitude than in 2020/21. But, I meant more how the baseline is higher than at the previous lows in 2020 & 2021, and it's now considered normal. That high baseline is endemicity.

DJ...in climate change some "politicians" proberbly would love to put the year 2000 as a "base line" and claim "climate collapse is not that bad"...In this pandemic one could use 2021 as a baseline and claim 2022 "is not that bad" simply ignoring pre-pandemic statistics...

"Politics" should not be in creative lies...blame games, pushing for more wars...The present "leaders" did "lead" us to "unseen horizons" ...there may be some time left to make a U-turn...








1) Those calling for abstinence for infection control were flippant and neglectful authorities, dismissing the concerns of the marginalized with an impractical suggestion 2) The people calling for continued mask use are not the authorities, but rather the marginalized themselves

-








Replying to 
What seems to be the only lesson from the pandemic, is that governments have weighed the cost on economy of prevention measures versus letting people die. As the population accepts+++ massive mortality, no need for Public Health anymore.

DJ..so what will be "western leaders" next step ? In climate change they defunded "unwelcome science"...[url]https://en.wikipedia.org/wiki/Karen_Silkwood[/url] or https://en.wikipedia.org/wiki/Karen_Silkwood

Karen Gay Silkwood (February 19, 1946 – November 13, 1974) was an American chemical technician and labor union activist known for raising concerns about corporate practices related to health and safety in a nuclear facility.

She worked at the Kerr-McGee Cimarron Fuel Fabrication Site in Oklahoma, making plutonium pellets, and became the first woman on the union's negotiating team. After testifying to the Atomic Energy Commission about her concerns, she was found to have plutonium contamination on her person and in her home. While driving to meet with a New York Times journalist and an official of her union's national office, she died in a car crash under unclear circumstances.

Her family sued Kerr-McGee for the plutonium contamination of Silkwood. The company settled out of court for US $1.38 million, while not admitting liability. Her story was chronicled in Mike Nichols's 1983 Academy Award nominated film Silkwood in which she was portrayed by Meryl Streep.

of course also in the west unwelcome voices have "accidents" (we did have some "bizarre cases" here in NL [url]https://nl.wikipedia.org/wiki/Maarten_van_Traa#Overlijden[/url] or https://nl.wikipedia.org/wiki/Maarten_van_Traa#Overlijden , [url]https://en.wikipedia.org/wiki/Assassination_of_Pim_Fortuyn[/url] or https://en.wikipedia.org/wiki/Assassination_of_Pim_Fortuyn ...other ways of silencing scientists are "promotions" to other fields of science, putting child porn on their computer, claims of tax fraud...). 

DJ-We are in unknown territory..."leaders" did "lead" us here...

Music; [url]https://www.youtube.com/watch?v=wJVpihgwE18[/url] or https://www.youtube.com/watch?v=wJVpihgwE18 "We've got to get out of this place" (Vietnam-war clip...)...

End of part 2

We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: October 01 2022 at 2:21am

let me go for a part 3...trying to look at how hyperinflation, refugees, energy problems are affecting Europe (including the UK) ability to deal with the pandemic...








Today is my last day at University College London, and I want to finally get out of my chest the nightmare I have lived in there for the past 4 years Please read my open letter about the situation and share it carefully with potential students that could take a post at UCL Astro

see [url]https://twitter.com/cosmonist/status/1575890925477580803/photo/1[/url] or https://twitter.com/cosmonist/status/1575890925477580803/photo/1 "anti science-science" going for PR...








Latest ONS infection data shows a modest increase in England, up 11% from last week's reported figure but this understates the true weekly increase, as only a further 3 days have been added. Looking at the daily estimates, the weekly increase is actually 26% to 17th Sept.

-


Please stop. We've all had enough of this shitshow.


Image



-








🚨 NEW: Devon’s health and social care system "under extreme pressure" with long waits in A&E:

DJ link [url]https://www.torbayandsouthdevon.nhs.uk/about-us/news-and-publications/news/2022/09/help-us-help-you-24247/[/url] or https://www.torbayandsouthdevon.nhs.uk/about-us/news-and-publications/news/2022/09/help-us-help-you-24247/ ;

Published: 30 September 2022

Devon’s health and social care system is under extreme pressure today and expected to be throughout this weekend, meaning people are facing longer than usual waits in our Emergency Departments. Rising COVID-19 numbers, high demand for services and delays to discharging people from hospital are all contributing to pressure on the system.

People are being urged to do their bit to help support services by choosing the best service for their needs if they are ill or injured, staying at home if they have the symptoms of an infectious illness such as norovirus (known as the winter vomiting bug), flu or COVID-19 and by picking up any family or friends promptly when they are ready to be discharged from hospital.

NHS Devon’s Chief Nurse, Darryn Allcorn said: “If you do attend an emergency department and it isn’t a life-threatening emergency you may be directed to a more appropriate service. We ask you to be understanding that this is because there are other people who are in much more urgent need of our care.

“We are also urging family and friends of people in hospital to pick up their loved ones as soon as possible when they are ready to be discharged and the hospital has contacted them.”

Another source;








Truss, Kwarteng, and Clarke doubling down on their ‘small state’ ideology and rolling the pitch for spending cuts is totally detached from reality on at least three fronts:

-

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: October 01 2022 at 2:56am

twitter....








Isn't this appalling? These are amongst the people we owe the most to in our society - the key workers. They shouldn't be having to skip meals to feed their kids.

link;[url]https://www.theguardian.com/society/2022/sep/30/nhs-nurses-not-eating-at-work-in-order-to-feed-their-children-survey-finds?CMP=Share_iOSApp_Other[/url] or https://www.theguardian.com/society/2022/sep/30/nhs-nurses-not-eating-at-work-in-order-to-feed-their-children-survey-finds?CMP=Share_iOSApp_Other ;

Some nurses are so hard up that they are having to not eat at work in order to feed and clothe their children, research among hospital bosses has found.

Lack of money is also prompting some NHS staff to call in sick in the days before they get paid because they can no longer afford the travel costs for their shift. Others are taking a second job outside the NHS in an effort to make ends meet.


The impact of the cost of living crisis on health service workers in England has emerged in a survey of chief executives, chairs and other senior figures in health trusts undertaken by NHS Providers, which represents trusts.

Miriam Deakin, the director of policy and strategy at NHS Providers, said: “There are heart-rending stories of nurses choosing between eating during the day and being able to buy a school uniform for their children at home.

“Increasing numbers of nurses and other staff, particularly in the lower pay bands, are finding they are unable to afford to work in the NHS.”

More than a quarter (27%) of trusts already operate food banks for staff, and another 19% plan to open one, to help relieve the acute financial difficulties faced by staff.

The survey also found that some staff:

  • Are stopping contributing to their NHS pension in order to free up cash.

  • Cannot fill up their cars because of petrol price rises.

  • Have mental health issues due to the stress of paying their bills.

The situation is so serious that some low-paid health staff, such as healthcare assistants, are quitting their jobs in the NHS and taking better-paid roles in pubs and shops instead, NHS chiefs said.

DJ-German (government run) [url]https://www.dw.com/en/german-russian-relations-through-history/g-61178567[/url] or https://www.dw.com/en/german-russian-relations-through-history/g-61178567 trying to ignore the economic-pandemic stories...[url]https://www.dw.com/en/coronavirus/s-32798[/url] or https://www.dw.com/en/coronavirus/s-32798 

[url]https://www.france24.com/en/europe/20220929-macron-faces-first-major-strike-since-re-election-as-unions-oppose-pension-reform[/url] or https://www.france24.com/en/europe/20220929-macron-faces-first-major-strike-since-re-election-as-unions-oppose-pension-reform in France ;

Fresh elections?

With deficits spiralling and public debt at historic highs, Macron views pushing back the pension age as one of the only ways the state can raise revenues without increasing taxes.

But his centrist party lost its majority in parliament in June, severely undermining his ability to make changes that are broadly unpopular.

Labour Minister Olivier Dussopt said that the 44-year-old head of state would not hesitate to call fresh elections if opposition parties voted down the government over the reform.

"If all of the opposition comes together to adopt a vote of no-confidence and brings down the government, he (Macron) will let French people decide and say what sort of a majority they want," Dussopt told the LCI channel. 

No opposition party has pledged to support the centrist minority government so far, but the conservative Republicans might still be persuaded, observers say.

DJ...another source;

[url]https://flutrackers.com/forum/forum/local-regional-communities-and-organizations/cidrap/959806-cidrap-covid-19-continues-upward-trend-in-europe[/url] or https://flutrackers.com/forum/forum/local-regional-communities-and-organizations/cidrap/959806-cidrap-covid-19-continues-upward-trend-in-europe ;

Sep 30, 2022

Europe's COVID cases showed more signs of rising last week, marking the first regionwide spike since the most recent BA.5 wave, the European Centre for Disease Prevention and Control (ECDC) said today in a weekly update.

In the past, increasing cases in Europe have come ahead of similar rises in other regions, so trends in Europe are a closely watched global indicator.

Seniors hit hardest in Europe


Cases in people ages 65 and older rose 9% compared to the previous week, which the ECDC said was led by recent increases in 14 of 26 countries in the European Union that reported data. Deaths continued a decreasing trend.

Generally, hospitalization and intensive care unit (ICU) markers were stable in the region, but of 27 reporting countries, 14 noted an increasing trend. The ECDC said the overall picture is that increasing transmission in the majority of countries is mainly affecting seniors, which is in turn impacting hospitals.

"Changes in population mixing following the summer break are likely to be the main driver of these increases, with no indication of changes in the distribution of circulating variants," the ECDC said.

In the United Kingdom, most COVID indicators rose last week compared to the previous week, the Health Security Agency (HSA) said yesterday, pointing out that hospitalizations are highest in those ages 85 and older and that officials have seen a large spike in hospitalizations in those older than 80.

Officials said the North East region had the highest hospital admission level and over the whole region, deaths remained stable.

Mary Ramsay, MBBS, who directs the HSA's public health programs, said, "It is clear now that we are seeing an increase which could signal the start of the anticipated winter wave of COVID-19." She added that the time to get a booster shot if eligible is now. "Cases have started to climb, and hospitalizations are increasing in the oldest age groups," Ramsay said.

Most US markers decline amid subvariant shifts


In the United States, COVID metrics continue to fall, as variant proportions continue to shift. In a weekly update, the Centers for Disease Control and Prevention (CDC) said the 7-day average for new daily cases decreased 13.1% compared to the week before, with the 7-day average for new COVID deaths down 6.7%.

The 7-day average for new daily COVID hospitalizations dropped 7.4% compared to the week before. Hospitalizations have decreased by 25% over the past month, with rates highest in adults ages 85 and older.

One measure that rose was the 7-day average for PCR test positivity, which increased slightly from 9.6% to 9.8%. Wastewater surveillance suggests that 53% of monitoring sites reported a decrease in SARS-CoV-2 levels, while 41% reported an increase.

Regarding variant proportions, BA.5 is still dominant, but continues to decline slowly as newer Omicron subvariants continue to rise slowly, the CDC said today in its latest proportion updates. BA.5 declined from 83.2% to 81.3% over the past week, while BA.2.75 rose from 1.2% to 1.4% and BF.7 rose from 2.4% to 3.4%. Also, the level of BA.4.6, seen at highest levels in the southern Midwest states, rose from 11.8% to 12.8%.

7.5 million have received updated booster


In other updates today, the CDC said more than 7.5 million people have gotten their updated booster doses, up from 4.4 million last week. However, it also noted that 49.9% of the eligible population has yet to receive any booster dose.

A new survey from the Kaiser Family Foundation (KFF) said half of the public has heard little or nothing about the new booster shots and many don't know if the CDC recommends them. The findings also suggest that one third of adults and nearly half of seniors say they've either gotten the new booster or intend to get it as soon as possible.

The survey found a bit of improvement in COVID vaccination for children, which suggests a 7% rise from July. However, half said they will "definitely not" get their child vaccinated against COVID.

On flu [url]https://flutrackers.com/forum/forum/united-states/seasonal-flu-2009-2014-including-h1n1-pandemic-2009-aj/925260-us-fluview-weekly-surveillance-flu-report-2021-2022-season-for-trend-analysis?view=stream[/url] or https://flutrackers.com/forum/forum/united-states/seasonal-flu-2009-2014-including-h1n1-pandemic-2009-aj/925260-us-fluview-weekly-surveillance-flu-report-2021-2022-season-for-trend-analysis?view=stream latest; H3N2 flu dominating over H1N1-flu cases increasing in the US...

DJ...[url]https://www.rivm.nl/griep-griepprik/feiten-en-cijfers[/url] or https://www.rivm.nl/griep-griepprik/feiten-en-cijfers flu-like symptoms are increasing in NL-however H3N2 detections are going down...(it is still early)...I miss NL numbers on MPX...they stopped reporting them ????

In general; the west is moving into a crisis unseen in recent history....Not because of disasters-but because of crazy politics....This pandemic was avoidable...the NATO expansion/sanctions war are a total disaster....Climate collapse is NOT stopped...[url]http://arctic-news.blogspot.com/2022/09/crossing-3c.html[/url] or http://arctic-news.blogspot.com/2022/09/crossing-3c.html "profits first" politics for sale have become a global disaster...

Music; [url]https://www.youtube.com/watch?v=bcLazPauA1c[/url] or https://www.youtube.com/watch?v=bcLazPauA1c There 's got to be a morning after....Maureen Mc Govern 1973...

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: October 01 2022 at 11:17pm

DJ, part 1,

Latest NL inflation year-to-year [url]https://nltimes.nl/2022/09/30/ministers-call-171-inflation-rate-terrible-extreme[/url] or https://nltimes.nl/2022/09/30/ministers-call-171-inflation-rate-terrible-extreme was 17,1%...Most of it related to increase of energy costs...DJ-And I do not expect those energy costs (increasing energy imports have to be paid in US$) to go down...

To limit inflation interest rates are also going up...this does not only affect companies, households...but also the healthcare sector...

Hospitals have "limited budgets" now face both high inflation and interest rates...at least part of medication, medical gear is imported-also outside the Euro-zone...so those costs also may go up...European Healthcare may see inflation costs for this sector close to 20% this year...

-At the same time we did see a CoViD-winterwave starting, flu-numbers (H3N2) increasing, MPX numbers (ignored in reporting) going up...I do not like cynicism-but a lot of the high-risk population could have died allready from heatwaves, earlier CoViD waves...delayed care...Only long/chronic CoViD may result in a new large group of high risk patients...

HCW-ers are exhausted..for now may get better pay working in other sectors...So increasing demand for healthcare is now facing a major decrease in healthcare capacity...We already were in a healthcare crisis...it is now getting much worse...[url]https://www.coronaheadsup.com/europe/europe-another-record-breaking-winter-wave-predicted/[/url] or https://www.coronaheadsup.com/europe/europe-another-record-breaking-winter-wave-predicted/ 

-[url]https://www.thailandmedical.news/news/latest-singapore-in-a-new-covid-19-wave-driven-by-various-new-omicron-variants-including-ba-2-75-with-an-average-of-about-4,000-new-cases-per-day[/url] or https://www.thailandmedical.news/news/latest-singapore-in-a-new-covid-19-wave-driven-by-various-new-omicron-variants-including-ba-2-75-with-an-average-of-about-4,000-new-cases-per-day Austria [url]https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table[/url] or https://www.worldometers.info/coronavirus/weekly-trends/#weekly_table has 8,529 new cases-last 7 days-per million of population (=0,85% of its population testing positive in the last seven days...) Taiwan 12,279-per million...Singapore 3,680 per million..

-[url]https://www.thailandmedical.news/news/warning-newer-sars-cov-2-variants-have-evolved-to-overcome-the-robust-innate-immune-system-of-children-infants-and-children-are-more-vulnerable-now[/url] or https://www.thailandmedical.news/news/warning-newer-sars-cov-2-variants-have-evolved-to-overcome-the-robust-innate-immune-system-of-children-infants-and-children-are-more-vulnerable-now lots of links in the article. Innate immunity is the immunity defense you are born with...findings indicate new variants now are better in getting around those defenses-making CoViD a major risk for babies, young children...(the idea of getting infected to boost immunity for CoViD-19 was wrong from the start-high risk! Not only for severe disease, long/chronic CoViD but also for MIS-C, Multi Inflamatory Syndrome, an overreaction of the immune system both seen in C children, A adults and N new borns...) 

-[url]https://www.thailandmedical.news/news/breaking-u-s-nih-study-finds-that-sars-cov-2-spike-proteins-and-mrnas-can-translocate-into-the-nucleus-of-host-cells-unlike-any-other-coronaviruses[/url] or https://www.thailandmedical.news/news/breaking-u-s-nih-study-finds-that-sars-cov-2-spike-proteins-and-mrnas-can-translocate-into-the-nucleus-of-host-cells-unlike-any-other-coronaviruses link to [url]https://www.biorxiv.org/content/10.1101/2022.09.27.509633v1[/url] or https://www.biorxiv.org/content/10.1101/2022.09.27.509633v1 ;

AAbstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe pathophysiology in vulnerable older populations and appears to be highly pathogenic and more transmissible than SARS-CoV or MERS-CoV [1, 2]. The spike (S) protein appears to be a major pathogenic factor that contributes to the unique pathogenesis of SARS-CoV-2. Although the S protein is a surface transmembrane type 1 glycoprotein, it has been predicted to be translocated into the nucleus due to the novel nuclear localization signal (NLS) “PRRARSV”, which is absent from the S protein of other coronaviruses. Indeed, S proteins translocate into the nucleus in SARS-CoV-2-infected cells. To our surprise, S mRNAs also translocate into the nucleus. S mRNA colocalizes with S protein, aiding the nuclear translocation of S mRNA. While nuclear translocation of nucleoprotein (N) has been shown in many coronaviruses, the nuclear translocation of both S mRNA and S protein reveals a novel pathogenic feature of SARS-CoV-2.

Author summary One of the novel sequence insertions resides at the S1/S2 boundary of Spike (S) protein and constitutes a functional nuclear localization signal (NLS) motif “PRRARSV”, which may supersede the importance of previously proposed polybasic furin cleavage site “RRAR”. Indeed, S protein’s NLS-driven nuclear translocation and its possible role in S mRNA’s nuclear translocation reveal a novel pathogenic feature of SARS-CoV-2.

DJ-The TMN article mentions more severe disease (even worse then SARS-1/MERS) specialy in the elderly...Also links to chronic/long CoViD...

End of part 1,

We cannot solve our problems with the same thinking we used when we created them.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: October 02 2022 at 2:14am

part 2

[url]https://www.wpc.ncep.noaa.gov/qpf/excessive_rainfall_outlook_ero.php[/url] or https://www.wpc.ncep.noaa.gov/qpf/excessive_rainfall_outlook_ero.php DJ-"Ian" did claim lots of lives...cause massive damage/flooding in a.o. Florida...[url]https://en.wikipedia.org/wiki/2022_Atlantic_hurricane_season#Season_effects[/url] or https://en.wikipedia.org/wiki/2022_Atlantic_hurricane_season#Season_effects "Fiona" did bring damage/flooding to a.o. Puerto Rico, Eastern Canada..."Julia" is now forming but most likely will stay on the Atlantic...Worldwide climate disasters worsen the pandemic perspectives....

Economy;








OPEC+ CONFIRMS IN-PERSON MEETING IN VIENNA ON OCT. 5: STATEMENT Between that 1mm cut and the SPR 1mm drain ending in three weeks, oil supply is about to drop big

Link to [url]https://www.zerohedge.com/commodities/opec-output-cut-looks-increasingly-likely-producers-narrow-down-options[/url] or https://www.zerohedge.com/commodities/opec-output-cut-looks-increasingly-likely-producers-narrow-down-options

OPEC+ meets on Wednesday, October 5, to discuss the market and fundamentals situation as oil prices have fallen below $90 per barrel, a level last seen just before the Russian invasion of Ukraine. It is "likely" that the group will agree on a cut, a source at OPEC told Reuters.

and; [url]https://www.zerohedge.com/commodities/us-hits-chinese-firms-new-sanctions-over-iran-oil-sanctions-busting[/url] or https://www.zerohedge.com/commodities/us-hits-chinese-firms-new-sanctions-over-iran-oil-sanctions-bustingThe US has slapped new sanctions on Chinese firms related to Iran’s petrochemical and petroleum trade, after years of reports of Chinese tankers engaged in sanctions-busting activity, and at a moment that a finalized restored JCPOA nuclear deal has all but collapsed.

-

And further according to the US Treasury readout, the actions target "Iranian brokers and several front companies in the UAE, Hong Kong, and India that have facilitated financial transfers and shipping of Iranian petroleum and petrochemical products."

DJ, of course India, China are also global pharma giants....For "the west" outlook is energy prices, medication-prices, inflation will go up...[url]https://en.wikipedia.org/wiki/Failed_state[/url] or https://en.wikipedia.org/wiki/Failed_state ;

failed state is a political body that has disintegrated to a point where basic conditions and responsibilities of a sovereign government no longer function properly (see also fragile state and state collapse). A state can also fail if the government loses its legitimacy even if it is performing its functions properly. For a stable state, it is necessary for the government to enjoy both effectiveness and legitimacy. Likewise, when a nation weakens and its standard of living declines, it introduces the possibility of total governmental collapse. The Fund for Peace characterizes a failed state as having the following characteristics:

Common characteristics of a failing state include a central government so weak or ineffective that it has an inability to raise taxes or other support and has little practical control over much of its territory and hence there is a non-provision of public services. When this happens, widespread corruption and criminality, the intervention of state and non-state actors, the appearance of refugees and the involuntary movement of populations, sharp economic decline, and military intervention from both within and without the state in question can occur.[1]

Metrics have been developed to describe the level of governance of states. The precise level of government control required to avoid being considered a failed state varies considerably amongst authorities.[2] Furthermore, the declaration that a state has "failed" is generally controversial and, when made authoritatively, may carry significant geopolitical consequences.[2]

DJ...with inflation getting out of control, massive distrust in politics/government (not doing their job), pandemics out of control with not enough health care capacity...some western states may have to face this perspective...








NYT daily totals indicate 13.7K U.S. COVID deaths for the month of September. That is nearly equal to the high estimate — 14K — of flu deaths for the 2021-2022 season (October-May).

DJ..."Flu-Rona" is very likely to get worse this year...co-infections of (the many-all still named) "Omicron" variants and "flu" will push excess deaths to record high levels...[url]https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory[/url] or https://en.wikipedia.org/wiki/2022_monkeypox_outbreak#Cases_per_country_and_territory did countries simply stop reporting on MPX ????

Stephen Reicher

@ReicherStephen
·
As Covid hospitalisation rise by 37% in a week, the President of the Royal College of Emergency Medicine says: "Covid just makes everything that much harder and it's entirely valid to link this with critical incidents being called across the country..." https://theguardian.com/world/2022/oct/01/latest-covid-surge-a-heavy-straw-on-camels-back-for-every-hospital-in-uk?CMP=share_btn_tw

DJ...I did start "scenario's" at the start of this pandemic early 2020...The present scenario's are "beyond the worst ones" I could think of....

To allow myself some optimism; What if somehow global conflicts decreased NOW ? A basic problem-making dealing with the pandemics much harder-still would be "printed money" created out of thin air...Due to climate collapse countries claim to go for "green energy" so banks are less willing to invest-long term-into fossil fuels...

Some claims are about 3 billion (out of the almost 8 billion) people did get infected with CoViD...even if only 1% would develop long/chronic CoViD it would be 30 million...A more realistic number may go to 1-in-8 ? Long/Chronic CoViD is the most widespread "form" of CoViD....Healthcare, education may have been hit very hard...

So even if we would be able to end major conflicts from a "pandemic perspective" we are in a much worse position then a year ago....

End of part 2...

We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: October 02 2022 at 2:30am

Let me go for a part 3...

UK [url]https://health-study.joinzoe.com/data#levels-over-time[/url] or https://health-study.joinzoe.com/data#levels-over-time self reporting CoViD symptoms now over 2,3 million (out of UK population of 68,5 million...) 


Shaun Lintern

@ShaunLintern
·
NHS England has identified 10 areas including big city regions like Brimingham and Leicester, which it fears could see a 'system failure' this winter when 999, A&E, hospitals and social care all collapse. twitter.com/ShaunLintern/s…

and 








Royal Liverpool hospital said it had very limited space in emergency departments and St George’s hospital in London asked people to go to A&E only in serious situations.

DJ....protests can become mass spread events....








Some more highlights from an astonishing  poll for  - Tory supporters, look away now: The PM’s net approval rating has fallen from -9 to -37 in a week. It’s a worse net rating than the -28 that Johnson registered in the final poll before his removal.

And 


Mike Galsworthy

@mikegalsworthy
·
It’s an important point that Truss & Kwarteng have no mandate from the British people for the hugely destructive actions they are taking. It’s worth registering this through the current surging petition—> https://petition.parliament.uk/petitions/619781







🔥This has now clocked past a quarter of a million signatures. 🔥 Do sign and share...
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Mike Galsworthy

@mikegalsworthy
·
It’s an important point that Truss & Kwarteng have no mandate from the British people for the hugely destructive actions they are taking. It’s worth registering this through the current surging petition—> https://petition.parliament.uk/petitions/619781
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Again...western countries sinking into a major political crisis....








I guess we have different definitions of what constitutes the beginning of a wave? Maybe we just have different definitions of autumn?

DJ...UK Office of National Statistics state UK cases going up-however "not sign of a new wave".....

We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein
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