Click to Translate to English Click to Translate to French  Click to Translate to Spanish  Click to Translate to German  Click to Translate to Italian  Click to Translate to Japanese  Click to Translate to Chinese Simplified  Click to Translate to Korean  Click to Translate to Arabic  Click to Translate to Russian  Click to Translate to Portuguese  Click to Translate to Myanmar (Burmese)

PANDEMIC ALERT LEVEL
123456
Forum Home Forum Home > Main Forums > General Discussion
  New Posts New Posts RSS Feed - Is Tamiflu Effective Against H1N1?
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Now tracking the new emerging South Africa Omicron Variant

Is Tamiflu Effective Against H1N1?

 Post Reply Post Reply
Author
Message
 Rating: Topic Rating: 1 Votes, Average 4.00  Topic Search Topic Search  Topic Options Topic Options
Guests View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Topic: Is Tamiflu Effective Against H1N1?
    Posted: December 28 2013 at 7:48pm
Ok you guys that are experts is Tamiflu effective against H1N1? I am not seeing anything on this subject.
Back to Top
Medclinician2013 View Drop Down
Valued Member
Valued Member
Avatar

Joined: September 17 2013
Location: Carmel
Status: Offline
Points: 9020
Post Options Post Options   Thanks (0) Thanks(0)   Quote Medclinician2013 Quote  Post ReplyReply Direct Link To This Post Posted: December 28 2013 at 11:03pm
http://www.webmd.com/cold-and-flu/news/20090707/tamiflu-resistant-swine-flu-in-us

This was in 2009. H1N1 was already developing resistance.

July 7, 2009 -- Is Tamiflu-resistant swine flu spreading in the U.S.?

A 16-year-old girl traveling from San Francisco was found to be infected with Tamiflu-resistant swine flu after triggering a temperature-monitoring device in the Hong Kong airport. That has set off a West Coast search for others who might be carrying the drug-resistant virus.

http://www.cbsnews.com/news/tamiflu-resistant-h1n1-cluster-reported/

March 2013


http://www.theguardian.com/world/2013/mar/18/swine-flu-resistant-tamiflu-scientists

Increasing numbers of cases of swine flu are being detected that are resistant to Tamiflu, the drug the UK and rest of the world stockpiled to fight a pandemic, according to scientists calling for greater global monitoring.

Even more worryingly, these strains of flu are appearing in patients who have never been treated with the drug, which means the strains are able to pass from one human to another.

Tamiflu, generic name oseltamivir, is one of the few treatments available for pandemic swine flu, although it is thought to be of limited effectiveness. The reluctance of the manufacturer Roche to release all the trial data has made it difficult to ascertain how limited. Nonetheless the drug can save lives if used early in the course of the illness.

Resistance to the drug has been shown before, but the new Australian data on its steady growth and the apparently easy transfer from one person to another of Tamiflu-resistant flu strains will alarm public health experts.

http://www.bloomberg.com/news/2013-03-18/tamiflu-resistance-in-2-of-h1n1-flu-cases-globally-study-finds.html

Tamiflu-resistant swine flu is turning up in about 2 percent of cases globally, researchers in Australia found, raising the risk that Roche Holding AG (ROG)’s pill may become ineffective in fighting the pandemic H1N1 virus.

Shades of never speaking the name of Moses (Ten Commandments) Henry N. is still alive and beating the bushes with his recombo stuff.

This is interesting though...

The CDC released a series of H1N1 sequences, which were largely from the first three weeks of November. Included were two sequences with H274Y, which correlates with the two Tamiflu resistance cases announce in the week 47 FluView. One of these sequences, A/Louisiana/13/2013 is closely related to the three earlier resistant sequences from Louisiana (A/Louisiana/07/2013, A/Louisiana/08/2013, A/Louisiana/10/2013), which signA cluster of seven people infected with a Tamiflu-resistant strain of pandemic H1N1 influenza has been identified by researchers in Vietnam and reported in the New England Journal of Medicine.

comment: Interesting question. It appears there might be a greater resistance than is currently known and this topic definitely merits more research.

Med
Medclinician - not if but when - original
Back to Top
Guests View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: December 29 2013 at 4:37pm
Thanks Med, I will use my Tamiflu if I get it or my son gets it! Better than nothing!
Back to Top
cobber View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote cobber Quote  Post ReplyReply Direct Link To This Post Posted: December 29 2013 at 5:41pm
Tamiflu is almost useless. 98% of influenza A/H1N1 in North America is resistant to Tamiflu. They still give it to patients as it has a mild effect

Relenza is the go. Its made to combat H1 and specifically H274Y. 

Funny thing is Tamiflu was originally made for H2/H9 but was also found to be useful on H1. It had the strange effect of rearranging the virus to fit the drug. Gotta get lucky sometimes.

I have Relenza stockpiled. Its expensive a hell, but i see it as an insurance policy. You should also stockpile Tamiflu as its still effective against H2 and H9.

Relenza a very unusual drug. Its a pill which is inserted into an inhaler devise. Its similar to the newer asthma inhalers. This delivery method gets the drug deep into the lungs where its most effective. Its akin to inhaling a tea spoon of talcum powder.

Back to Top
Guests View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: December 31 2013 at 6:45pm
cobber how did you get the Relenza? I have to get a script from my doc for the Tamiflu and that is not easy.
Back to Top
Johnray1 View Drop Down
Valued Member
Valued Member
Avatar

Joined: April 23 2006
Location: United States
Status: Offline
Points: 8159
Post Options Post Options   Thanks (0) Thanks(0)   Quote Johnray1 Quote  Post ReplyReply Direct Link To This Post Posted: December 31 2013 at 7:02pm
FluMom,change doctors. Johnray1
Back to Top
cobber View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote cobber Quote  Post ReplyReply Direct Link To This Post Posted: January 02 2014 at 4:48am
Tell your doctor you are flying to Asia and are concerned about birdflu. That's what i did. (i actually went)

Your doctors really shouldn't limit your access to drugs if you make a reasonable request. Just tell them you have an emergency kit and want certain supplies. Most doctors i know love dealing out the drugs.

If they are cool with that then also hit em up for antibiotics too. ;)
Back to Top
cobber View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote cobber Quote  Post ReplyReply Direct Link To This Post Posted: January 02 2014 at 4:50am
PS: Some doctors are wankers and will lecture you. Pissthem off and find a new doctor.
Back to Top
jacksdad View Drop Down
Executive Admin
Executive Admin
Avatar

Joined: September 08 2007
Location: San Diego
Status: Offline
Points: 47251
Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: January 02 2014 at 6:52am
FluMom - Relenza is prescription only but it is still believed to be effective against H1N1 whereas widespread resistance to Tamiflu is starting to show up.
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
Back to Top
Mold_Guru View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Mold_Guru Quote  Post ReplyReply Direct Link To This Post Posted: February 26 2014 at 9:22am
Though I received the seasonal flu vaccine, I was infected with H1N1 in November. It was within 48 hours of my initial symptoms and the urgent care physician prescribed Tamiflu. It had no discernible effect and I was quite ill for two weeks. I just recently acquired Type B and was prescribed Tamiflu. This time, I recovered within a few days and my overall symptoms were minimal.
Back to Top
Kilt2 View Drop Down
Adviser Group
Adviser Group
Avatar

Joined: December 17 2007
Status: Offline
Points: 7414
Post Options Post Options   Thanks (0) Thanks(0)   Quote Kilt2 Quote  Post ReplyReply Direct Link To This Post Posted: February 26 2014 at 5:04pm
Tamiflu and Relenza are Neuraminidase inhibitors.

The death rate (RoM) with those in hospitals with H5N1 and H7N9 would be a lot higher without them.

They help - they are not a magic bullet.

The virus will mutate around them.
And I looked, and behold a pale horse: and his name that sat on him was Death, and Hell followed with him.
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down