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Pre-Pandemic covid antibody finding Italy |
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Pixie
Admin Group Joined: June 05 2006 Location: United States Status: Offline Points: 19668 |
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Posted: November 14 2020 at 2:09pm |
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy Show all authors Giovanni Apolone*, Emanuele Montomoli*, Alessandro Manenti, ... First Published November 11, 2020 Research Article https://doi.org/10.1177/0300891620974755
Abstract There are no robust data on the real onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and spread in the prepandemic period worldwide. We investigated the presence of SARS-CoV-2 receptor-binding domain (RBD)–specific antibodies in blood samples of 959 asymptomatic individuals enrolled in a prospective lung cancer screening trial between September 2019 and March 2020 to track the date of onset, frequency, and temporal and geographic variations across the Italian regions. SARS-CoV-2 RBD-specific antibodies were detected in 111 of 959 (11.6%) individuals, starting from September 2019 (14%), with a cluster of positive cases (>30%) in the second week of February 2020 and the highest number (53.2%) in Lombardy. This study shows an unexpected very early circulation of SARS-CoV-2 among asymptomatic individuals in Italy several months before the first patient was identified, and clarifies the onset and spread of the coronavirus disease 2019 (COVID-19) pandemic. Finding SARS-CoV-2 antibodies in asymptomatic people before the COVID-19 outbreak in Italy may reshape the history of pandemic. |
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Technophobe
Assistant Admin Joined: January 16 2014 Location: Scotland Status: Offline Points: 88450 |
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Well that does three things:........ It prompts a great theory as to why Italy was hit so hard at the beginning. It makes Trump's shutting of the borders with China look really pointless, especially as there was no attempt to deal with the virus already inside the USA and minimal testing. It makes China even more culpable for the worldwide spread, because it reveals the depth of its coverup. |
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How do you tell if a politician is lying?
His lips or pen are moving. |
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ksc
Adviser Group Joined: February 09 2020 Status: Offline Points: 10995 |
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...or the antibody test is registering false positives. |
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ksc
Adviser Group Joined: February 09 2020 Status: Offline Points: 10995 |
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Pre-existing coronavirus antibodies could help protect children against new pandemic strainhttps://medicalxpress.com/news/2020-11-pre-existing-coronavirus-antibodies-children-pandemic.html In their paper, published in Science today (Friday 6 November), the scientists found that some people, notably children, have antibodies reactive to SARS-CoV-2 in their blood, despite not ever having being infected with the virus. These antibodies are likely the result of exposure to other coronaviruses, which cause a common cold and which have structural similarities with SARS-CoV-2. The researchers made this discovery while developing highly sensitive antibody tests for COVID-19. To see how well their assay tests were performing, they compared the blood of patients with COVID-19 to patients who had not had the disease. Surprisingly, they found that some people who had not been exposed to SARS-CoV-2 had antibodies in their blood which would recognize the virus. To confirm their findings, they analyzed over 300 blood samples collected before the pandemic, between 2011 and 2018. Nearly all samples had antibodies that reacted with common cold coronaviruses, which was expected given how everyone has been exposed to these viruses at some point in their lives. However, a small fraction of adult donors, about 1 in 20, also had antibodies that cross-reacted with SARS-CoV-2, and this was not dependent on recent infection with a common cold coronavirus. Notably, such cross-reactive antibodies were found much more frequently in blood samples taken from children aged 6 to 16. |
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