Hi again.
Here is link to french article talking about the younger patients in ICU in Paris. 2 things to consider could be going on. Please read them both as they give different reasons. 1) According to press release (see link) it is a numbers game. Basically at start of this second surge around mid August, it was prominently younger people getting it. It did cause a rise in young people in ICU. They go on to say these numbers were very small and appeared high and alarming when expressed as a percentage ( rather than case numbers), because they were few older people catching the virus as they were still self shielding. Now they say the percentages in ICU of various age groups is reverting back to levels seen back in April dominated by older patients. They say the huge amount t of younger people infected inevitably have passed it to older relatives and the over all numbers of patients in ICU have surged. This influx of older people into ICU has now diluted out those patients of the younger age group who now make up a smaller percentage again. 2)That's what their official line is, but USK often what people are experiencing first hand is a more accurate picture. If your friend is reporting first hand that they are even now continuing to see predominantly younger patients thats troubling news, and may cast doubt on above news report. This is my thoughts so no links. Firstly we would need to exclude bias. Is their a chance their ICU serves an area where demographics are a younger population, such as a large University area, student accommodation and fewer older residents. So maybe older patients would be normally under represented. Or do they work in paediatrics which I believe are up to 18 years of age in France. Or are these young people taking beds filled before the second surge came so are catering for the early younger patients and not having room to admit the older patients which are now appearing in last few weeks. If this bias is not in place and If they are working in a general ICU in a mixed population and they are daily admitting younger patients, then that is really significant information. I would worry if your young patients are turning up in numbers in ICU that this might be a second exposure. Some viruses get worse the second time around due to antibody dependent enhancement (ADE) This would be concerning if young people had virus mild/asymptomatic and undetected in spring summer, and now have caught it again and it is worse the second time. We talk about ADE in another thread which Carbon linked too. Maybe your friend is seeing the effects of this rather than coinfection with flu, or a mutated virus. Flu hasnt really hit us yet, and there is no proof of a significant effect of a mutation in sequencing analysis to date. Thanks for your info. It is very worrying. Hopefully just a blip but worrying development were it to continue. Thanks so much for the info. Hz x
ANALYSIS: How France's most seriously ill Covid-19 patients are getting younger - The Local https://www.thelocal.fr/20200924/analysis-why-frances-most-seriously-ill-covid-19-patients-are-getting-younger - https://www.thelocal.fr/20200924/analysis-why-frances-most-seriously-ill-covid-19-patients-are-getting-younger
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