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Alzheimer's plaques and sleep

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Printed Date: April 23 2024 at 6:21am


Topic: Alzheimer's plaques and sleep
Posted By: Hazelpad
Subject: Alzheimer's plaques and sleep
Date Posted: February 15 2022 at 9:56am

Totally off topic but sometimes its nice to talk about new important articles.

Anyway one of risk factord for covid mortality is Alzheimer's  disease probably because patient  happy hypoxia symptom will be more suppressed in damaged neurological pathways.

However I found this article showing how the plaques can be blown out of our brain by good sleep cycles.  This combines  with other research showing a similar effect with exercise.

Thought it interesting maybe delays onset or prevents but won't stop once started.

Hz x

Quote

The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to new research. The research underscores the importance of healthy sleep habits in preventing the protein Amyloid-Beta 42 (AB42) from forming clumps in the brain, and opens a path to potential Alzheimer's therapies


https://www.sciencedaily.com/releases/2022/02/220210154215.htm - https://www.sciencedaily.com/releases/2022/02/220210154215.htm




Replies:
Posted By: KiwiMum
Date Posted: February 15 2022 at 11:56am

Thanks for posting that Hazelpad. My mother died from dementia and I'm anxious not to go the same way. Interestingly enough, she had appalling sleep patterns that got worse as she aged. She also never exercised in her life after leaving school. So it ties in.



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Posted By: Hazelpad
Date Posted: February 15 2022 at 4:13pm

It's not nice to have that over your head but many of the dementia now appear to have environment and lifestyle choices acting on genetics so it probably is not down to genetics alone.

Here is link for exercise research came out this month.  Quite a good study.

Basically even in patients full of toxic proteins linked to cognitive disorders, they had less effect in those that stayed fit and active.

HZ x


Exercise alters brain chemistry to protect aging synapses: Enhanced nerve transmission seen in older adults who remained active -- ScienceDaily

https://www.sciencedaily.com/releases/2022/01/220107100955.htm - https://www.sciencedaily.com/releases/2022/01/220107100955.htm



Exercise alters brain chemistry to protect aging synapses

Enhanced nerve transmission seen in older adults who remained active

Date:
January 7, 2022
Source:
University of California - San Francisco
Summary:
When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a new study has found

This protective impact was found even in people whose brains at autopsy were riddled with toxic proteins associated with Alzheimer's and other neurodegenerative diseases.




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