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Tracking the next pandemic: Avian Flu Talk

Swine flu second wave worsens

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    Posted: August 04 2010 at 10:36am
Ahhh.  Wave two?
 
 
 
Swine flu second wave worsens
 
There's been a sharp rise in cases of swine flu and the Health Ministry is expecting it to get worse.

Director of Public Health Dr Mark Jacobs says the country is in a second wave of a pandemic.

"There are just over 400 confirmed cases around the country and just under 200 people in hospital and those numbers are continuing to increase and it's still probably reasonably early days with this second wave."

Dr Jacobs says the swine flu has claimed two lives so far this year.
 
 
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Wellington, Aug 4 NZPA - Health officials are urging people to get a "last minute jab" in a bid to avoid this year's wave of pandemic influenza hitting New Zealand.

"For anyone still thinking about getting vaccinated, now is the time to do it," public health director Mark Jacobs said today.

There were 15,500 doses left of "seasonal" vaccine -- which also protects against pandemic swine flu -- but the vaccine would take up to two weeks to provide protection and young children required two shots three weeks apart to be protected.

Health Ministry data showed increasing numbers of people coming down with flu symptoms, particularly in the northern half of the North Island, indicating a second wave of pandemic H1N1 "swine flu" sweeping the country in little more than a year.

The first wave was on April 25, 2009, when students from Rangitoto College, on Auckland's North Shore, introduced the H1N1 "swine flu" from Mexico via Los Angeles.

An estimated 18 percent of the country's population caught the virus, with the highest rate of infection among school-age children.

Medical scientists later said that relatively few older people were infected last winter, with the nation's elderly largely protected from serious effects because previous influenza viruses, particularly from before 1957, gave them some immunity.

But last year's pandemic wave also showed that younger people with certain health conditions, including pregnancy, were particularly vulnerable to serious illness and death from the virus, and should be targeted for vaccination, along with specific population groups such as children and Pacific Island and Maori people.

Today, health officials said the hospital districts which were suffering worst this winter tended to be the ones with relatively low influenza rates last year, such as Bay of Plenty, and Taranaki.

It was likely that district health boards with lower rates of hospitalisation last year could have greater numbers of people still susceptible to the disease -- including Otago, West Coast, Wairarapa, Whanganui, Nelson Marlborough and Southland.

The Wairarapa is already battening down the hatches, with up to 45 percent of schoolchildren absent due to the rapid spread of H1N1 flu.

Medical officer of health for the greater Wellington region Annette Nesdale said the first signs of high levels of sickness in schools came last Friday, with children arriving at school feeling well in the morning, but falling ill by lunchtime, with most presenting with high fever, chills, headaches and a cough.

 
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Severe swine flu hits New Zealand schools

A virus sweeping through the Wairarapa has been confirmed as swine flu.

The results of swabs taken from the first wave of children affected earlier this week have returned as positive.

So far five schools have been affected with between 20 and 50 per cent of their rolls affected, as children are sent home immediately.

More than 400 children are currently home sick, and Masterton Medical Centre alone is dealing with more than 60 patients a day suffering severe flu like symptoms.

via Wairarapa confirmed as swine flu | Stuff.co.nz

 
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Hi Albert, ya me still around..I wonder what this fall/ winter will bring? Still think that Avain has a chance of combining with the swine flu?


India: Swine flu on the rampage; toll rises to 20
Hyderabad, August 05: The dreaded "swine flu" (Snip) is on the rampage in the State once again. According to latest reports, 17 nursing students, suffering from swine flu symptoms, were being treated in the Gandhi Hospital in Secunderabad. The condition of three students is stated to be causing anxiety. (Snip) The nursing students have complained that they were not being looked after well by the medical staff (Snip) in the hospital.

With the death of a swine flu patient Raghupathi of Jammikunta of Karimnagar district this morning in Gandhi Hospital, the toll of the disease has risen to 20, including seven pregnant women and two lactating mothers. http://www.siasat.com/english/...


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Older Article..hope the source is good..Coyote


Concerns Grow Over Possible H1N1-H5N1 'Reassortment,' Other Mutations
04Dec
2009
by Anthony L. Kimery | HSToday

'The obvious risk is of H5N1 combining with the pandemic [H1N1] virus'

Virologists and influenza authorities are becoming increasingly concerned that the 2009 A-H1N1 flu virus could “reassort” with the highly virulent H5N1 avian flu that’s still prevalent in parts of the world like China, and that a mutation could occur resulting in a new strain that has the lethality of H5N1 and the human transmissibility of A-H1N1.

The concerns have grown in the wake of revelations that mutations of the H1N1 flu virus had been found in Norway and elsewhere, leading experts to fear that it might just be a matter of time before there’s a reassortment of H1N1 and H5N1.

This comes as the World Health Organization (WHO) reported very high pandemic activity in Italy, Norway, the Republic of Moldova, the Russian Federation (Urals region), and Sweden.

Bulgaria, Denmark, Finland, Germany, Iceland, Ireland, Lithuania, Luxembourg, Poland, Portugal, the Russian Federation, Serbia, Turkey, and Ukraine also reported high pandemic activity.

Meanwhile, authorities said they believe the peak of the A-H1N1 pandemic's second wave hasn’t yet been reached in some parts of the world.

WHO said it’s keeping a "very careful” eye on the reported mutations in order to ascertain whether it is causing more severe illness diseases than the A-H1N1 virus.

"We really need to look at this very carefully to see whether it is in fact associated with severe cases," WHO spokesman Thomas Abraham told reporters. He said investigations by WHO's collaborating network of labs will be able to provide a better "understanding … about clinical features associated with the infection of this particular form of the virus."

Since it emerged, the A-H1N1 virus has constantly been mutating, authorities said. So far, most of these mutations have no clinical significance, but "occasionally we come across a virus that might have clinical significance,” Abraham said.

WHO warned that the H5N1 virus has emerged in poultry in Egypt, Indonesia, Thailand and Vietnam just as the H1N1 pandemic influenza continues its rampage across the world.

Not only does this place “those in direct contact with birds - usually rural folk and farm workers - at risk of catching the often-fatal disease,” but “the virus could undergo a process of ‘reassortment’ with another influenza virus and produce a completely new strain," WHO stated.

"The most obvious risk is of H5N1 combining with the pandemic ... [H1N1] virus, producing a flu virus that is as deadly as the former and as contagious as the latter."

That the two flu strain could merge, reassert, and produce a new hybrid influenza strain combining the worst elements of each of the viruses is a possibility that authorities have been worrying about ever since the spread of the A-H1N1 virus increased to pandemic level.

“We don’t know if this is possible, but we are certainly aware of the risk,” Dr. Shin Young-soo, WHO Regional Director for the Western Pacific,” told The Philippine Star. “We are on alert for this development.”

“Influenza viruses are unpredictable. In areas where [A-H1N1] is endemic, we and our partners and national governments are working to build surveillance systems to identify changes in the behavior of the virus,” Shin said. “We are also focusing on early-response capacity to reduce the potential threats to human health.”

Virologists told HSToday.us that “it’s very possible that the two flu strains could combine – this reassortment that we talk about – that could result in a mix of the two,” as one explained. “Of course, what we are concerned about is a mutation that contains the worst characteristics of the two viruses.”

Zhong Nanshan, director of the Guangzhou Institute of Respiratory Diseases in China's southern Guangdong province, warned that China has to be on high alert to any mutation and changes in the virulence of A-H1N1.

"This is something we need to monitor, the change, the mutation of the virus. This is why reporting of the death rate must be really transparent,” he told Reuters Television, adding, China, as you know, is different from other countries. Inside China, H5N1 has been existing for some time, so if there is really a reassortment between H1N1 and H5N1, it will be a disaster.”

WHO reported more than half-a-million laboratory confirmed cases of H1N1 worldwide in mid-November and close to 7,000 deaths, but stressed that in reality that figure is likely much, much higher.

Across Europe, the number of deaths related to pandemic H1N1 has doubled nearly every two weeks since mid-October.

US influenza and public health authorities agreed in interviews with HSToday.us. They said the number of people infected in the US is undoubtedly “much higher” than the number of lab-confirmed cases given that most people who exhibit traditional H1N1 sickness symptoms are not tested to determine if they have H1N1 or a seasonal flu virus strain.

HSToday.us reported last week that four patients at Duke University Medical Center in Durham, NC, at least five persons in a hospital in Wales, and a father in Quebec, Canada become infected with an apparently mutated strain of H1N1 that is resistant to Tamiflu (oseltamivir), the leading antiviral of choice to treat influenza in lieu of having a vaccine.

Meanwhile, Norwegian health authorities reported a potentially significant mutation in H1N1 that could be responsible for the severest symptoms in those infected by the strain - especially persons most at risk to the virus.

Authorities have been monitoring this development very carefully because of concerns that it, too, might become resistant to Tamiflu, and, possibly, other antivirals if they become as widely administered as oseltamivir.

Similar mutations have been reported elsewhere, but haven’t necessarily provoked a more virulent virus or proven to be less resistant to Tamiflu or other antivirals. Nevertheless, authorities increasingly are concerned.

Virologists have been worried for some time that antiviral-resistant influenza could become a serious problem during a pandemic, as antivirals are the primary defense against a pandemic until an effective vaccine is developed and distributed.

Additionally, the Centers for Disease Control and Prevention (CDC) reported during a November 25 press briefing that there's been "a worrisome spike in serious pneumococcal disease" linked to A-H1N1 had appeared in the CDC's Active Bacterial Core surveillance program that monitors infections at ten locations across the nation.

CDC reported a tripling of cases of severe, life-threatening bacterial infections at the monitoring sites.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: August 05 2010 at 9:55am
Hi coyote, I suppose we're all still around.  If you see the old timers resurface, that could be a bad sign, as something has got their attention.
 
As far as H5N1 making its move, the possiblity does exist.  In fact, the WHO snuck this one in on us below.  They gave H5N1 its own pandemic alert grid.  It's new because notice the WHO's typo below with "Inlufenza".  Either way, they have now recognized H5N1 as a specific pandemic threat.
 
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Ya Think Wink
WHAT TO DO????
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Dang, guess when I get better I need to do an inventory on all my meds. Still have Tamiflu and now have some Cipro now. I just keep adding to my stores just in case.
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Swine flu makes ill in Northeast, shuts school
 
The H1N1 influenza outbreak that hit last year is spreading in three Northeastern provinces, making nearly 40 people ill so far and prompting a school to close.
 
In Ubon Rathatchani province, 20 senior education officials caught the disease, known as human swine flu, after attending a seminar there, and 10 of them were admitted to hospital after catching the flu on Thursday.

The officials are from neighbouring Amnat Charoen province. They have been advised to seek further treatment in their home province, after the seminar was called off and they were asked to leave Ubon Rathani.

About 100 officials scheduled to attend the seminar fell ill but were diagnosed with common and seasonal flu. All hotels where they were staying have been sanitised.

In Buri Ram, Marie Anusorn School in Muang district closed immediately after 19 fifthgraders contracted the flu. One of them is receiving hospital treatment.

The school closed yesterday morning and will reopen on Monday. School management has issued an apology to parents for the immediate closure without prior notice. Mattresses and sleepwear of toddlers in its kindergarten classes have been sanitised.
 
Screening of suspected cases will be conducted upon the school's reopening on Monday, and those with symptoms will be excused from classes.
 
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This is the second time in the last few days that we've seen an unusually high hospitalization rate at 50%.  Not sure what's going on with that one. 
 
My guess, the infamous 1918 second wave is underway and heading to North America.  The second wave was delayed, and different, because of air travel.  Without air travel in 1918, the virus would move very slow resulting in a different way of how wave two would start.  The pandemic modeling may have been wrong.   In this case, the whole planet has been saturated with wave one because of travel, now wave two will begin.   Ironically enough, air travel may have had the opposite effect in this case.
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Thanks for the update! We're just going to need to keep a close watch on this!
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Mutation???    Shocked
 
 

Swine flu back in Kolkata, minister among 12 ill

 
KOLKATA: Swine Flu has hit Kolkata yet again, this time probably in a mutated form. Twelve patients have tested positive for the H1N1 virus in the last 11 days, including minister Nandagopal Bhattacharya. Three tested positive on Thursday itself.

A 25-year-old man, Manoj Kriplani, has also tested positive. A patient of chronic renal failure, he returned to the city from Vellore recently. His condition is reported to be critical. Three patients are being treated at Beliaghata ID Hospital. More samples are being sent to the H1N1 testing laboratory attached with the National Institute of Cholera and Enteric Diseases, Beliaghata.

Bhattacharya, who handles the water resources department, has been ailing for quite some time.  "He has tested positive for H1N1 and is undergoing treatment," health minister Surjya Kanta Mishra told TOI late on Thursday. "We are treating swine flu patients with tamiflu. Though the situation is not yet alarming, isolation wards have been kept ready in case the need arises. All other protocols are being followed,” Mishra said.

Last year, swine flu struck in the height of summer. This time, it has come during (the delayed) monsoon. The worrying aspect this year is that the virus seems to have originated locally, unlike in 2009 when it was brought into the country by travellers from North America and South-East Asia.

It is likely that the H1N1 virus has remained dormant in Kolkata and mutated over the last 14 months, say experts. "It seems the virus has been brewing in our backyard. Influenza viruses like H1N1 have a tendency to mutate and linger. They return in waves and with varying degrees of intensity," said Tomonash Bhattacharya, a tropical medicine specialist.


The first case of swine flu in Bengal was detected on May 11, 2009 and the figure started swelling in August and September. There were 130 cases of confirmed H1N1 cases in Bengal in 2009. The scare died down slowly without any fatalities.

http://timesofindia.indiatimes.com/city/kolkata-/Swine-flu-back-in-Kolkata-minister-among-12-ill/articleshow/6174478.cms

 
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Wave two mutated strain?    
 
 
Swine flu virus bred locally, feel doctors [Kolkata
 
KOLKATA: The H1N1 virus, which is responsible for causing swine flu, has returned a little over a year after it struck Kolkata last. While it had broken out at the height of summer in 2009, this time it has struck in monsoon. The worrying aspect this time is that the virus has originated locally, unlike the last occasion, when it had been brought into the country by travellers from North America and south-east Asia.
 
is quite possible, experts pointed out, that the H1N1 has remained dormant in Kolkata and has mutated over the last 14 months. "We need to study the epidemiological history of the patients and check if they had come into contact with people travelling from abroad or other states. But it seems that the virus has not been brought from elsewhere, but has been brewing in our backyard. Influenza viruses like H1N1 have a tendency to mutate and linger. They return in waves and with varying degrees of intensity," said Tomonash Bhattacharya, a tropical medicine specialist.

It is too early, however, to predict if we are headed for a severe outbreak this year, Bhattacharya added. "There is no pattern to the waves. Depending on factors like the weather, it could be severe in successive years," he said.

But the timing, said experts, is not unusual. Any influenza virus, including H1N1, is let loose by fluctuations in weather. The erratic climatic conditions now prevailing in Kolkata are ideal for an outbreak, they felt. The fact that the temperature has been sliding up and down combined with occasional showers has helped the virus to spread. "Any influenza virus gets stimulated by temperature fluctuations and inconsistent rainfall. Chances are that the virus had been floating around and has now got the right stimulus and turned potent. The virus won't disappear till the mercury starts dropping," said a virologist.

The initial symptoms of swine flu are similar to symptoms of regular flu. People with flu symptoms (see box) should seek medical attention, though mortality rate is not high for swine flu. "Many get cured without even knowing that they had the virus. But there is need to be cautious. The reason is that it is very infectious and a minor endemic could turn into a major outbreak in days," said Bhattacharya. For Reprint Rights: timescontent.com

 
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This new strain (wave two) will hit the U.S. the hardest as it picks up steam.   This could get ugly.
 
 
 
19 more swine flu cases in West Bengal
KOLKATA, July 27, 2010
var addthis_pub = "thehindu"; Staff Reporter

Nineteen new cases of swine flu were detected by the West Bengal Health Department on Monday. The total number of patients affected by the virus in the State has risen to 61 since July 1.

According to Dr. Asit Biswas, nodal officer of the health department's swine flu wing, condition of two of the afflicted patients is critical.

Dr. Biswas added that 21 of the 61 patients were admitted to the Beliaghata ID Hospital .

A 58-year-old cancer patient had died of the flu on July 20 marking the first death due to the A (H1NI) virus in the State.

The fact is that none of the patients affected has any past record of travelling abroad or coming in contact with anyone who had made a foreign trip.

It has led the doctors to believe that the patients are being infected by a re-assorted strain of the A (H1N1) virus which is a mutated form of the original A (H1N1) virus and which breeds profusely during the rainy season.

 
 
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New Delhi:  The swine flu virus, which has been on a resurgent course since the beginning of monsoons, tightened its grip over the country during the past week with 21 deaths being reported from various parts.

Kerala and Maharashtra again bore the brunt during the week (July 13-19) with the states reporting eight and 11 cases respectively. One death was reported from Delhi and another from Gujarat.

The two states had reported 16 out of the total 17 deaths the earlier week (July 7-13).

Swine flu cases have seen an upward surge since the onset of monsoons. Out of the 332 cases reported during the week, only one case is imported and rest are indigenous cases.
Till date, samples from 14,7250 people have been tested for Influenza A H1N1 in Government Laboratories and a few private Laboratories across the country and 34,115 of them have been found positive. 

Read more at: http://www.ndtv.com/article/india/swine-flu-cases-on-the-rise-21-deaths-in-one-week-38436?cp
 
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote DANNYKELLEY Quote  Post ReplyReply Direct Link To This Post Posted: August 07 2010 at 4:23pm
THANKS ALBERT!!!
WHAT TO DO????
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No prob Dan.  Long time no talk buddy.  

 
 
 
 
 
 
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Here is one of the indicators.  Infection rate is double.  Now we need severity/virulence.  

 

 

Swine flu infection rate at 40%, alert sounded

aug 5th 
 
PUNE: National Institute of Virology (NIV) has advised people to be alert and take precautionary measures to ward off swine flu as the infection rate has risen to 40% now.

"There has been a significant rise in the number of people suffering from the H1N1 influenza this year compared to 2009, when the rate was between 15% and 25%. However, it has already touched 40% now with a spurt in cases during the second wave. Precaution is the key to protection from the infection," NIV director AC Mishra told TOI on Wednesday.

"We, at the NIV, have been receiving about 200 throat swab samples from all over Maharashtra daily. Many of these are coming from far flung areas that remained unscathed last year. There has been an increase in the number of cases," he said.

Elaborating, Mishra said, "The pandemic H1N1 virus has become a dominant strain"
he said.

 
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Ahhh.  This is about the 3rd time large clusters are taken to the hospital with some seriously ill.  Severity....
 
 
17 Nursing students admitted to Gandhi Hospital, three stated to be in serious condition
Aug 5th 

Though the health officials are claiming that swine flu is under control in the state, 17 nursing students have been admitted to Gandhi Hospital in Secunderabad after they displayed symptoms of having contracted the dreaded disease on Thursday.

It is believed that 3 of these students are in a serious condition.

The blood samples of the nursing students have been sent to Chest Hospital in Erragadda after the swine-flu like symptoms were noticed.

Meanwhile, the nursing students have complained that they are not being looked after well by the authorities at the hospital.

Earlier, Raghupathi, a person hailing from Jimmikunta in Karimnagar district, who was undergoing treatment for swine flu in Gandhi hospital, died on Thursday.

The health department authorities have sounded an alert, as the onset of monsoon is believed to be the reason for fresh cases of swine flu.

Swine flu coordinator at Chest Hospital said the humidity and the cold climate is ideal for the virus to spread rapidly, and urged people to be cautious over the disease.

The influenza has so far claimed the lives of 20 people in the state."
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: August 08 2010 at 7:33am
This 2nd wave could get ugly.  India claiming mutation without testing?  That would indicate that the symptoms are significantly more severe, and they may not need testing to figure this one out.  
 
Still havent heard about people being released from the hospitals yet.  Let's hope it's not a one way ticket in...
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This article came out mid summer, but it could explain the mutation.
 
 
Pandemic virus enters pigs in HK, swaps genes: study
 
(Reuters) - The H1N1 swine flu virus has been spreading quietly in pigs in Hong Kong and swapping genes with other viruses, and researchers said the findings support calls for tighter disease surveillance in pigs before new bugs can emerge and infect people.

The finding, published in Science on Friday, is important as it supports the theory that flu viruses infecting swine can swap genes with other viruses that are in pigs, including more dangerous bugs like the H5N1 or H9N2 bird flu viruses.

Malik Peiris, an influenza expert who worked on the study, said the discovery underlines the importance of disease surveillance in pigs.

"It demonstrates the pandemic virus can easily go back to pigs. Once it does so, it can reassort with other pig viruses and give rise to potentially unexpected consequences," said Peiris, a microbiology professor at the University of Hong Kong.

Peiris and colleagues, including Guan Yi at the University of Hong Kong, have found pandemic H1N1 viruses in nasal swabs taken from apparently healthy pigs at a Hong Kong abattoir during routine checks since October 2009.

"From genetic analysis, what it suggests is each of those viruses we found in pigs all came from humans," Peiris said in a telephone interview.

"It is not surprising because the pandemic virus emerged from pigs, so it is not surprising that it goes back to pigs."

PANDEMIC VIRUS SWAPS GENES IN PIGS

A sample isolated from Hong Kong pigs in January 2010 carried genes from three viruses - the pandemic H1N1, a European "avian like" H1N1 and a so-called "triple reassortant" virus containing bits of human, pig and bird flu viruses which was first discovered in North America in 1998.

"This suggests that the pig is a place where the pandemic virus might actually change and reassort and get new properties possibly," Peiris said.

"The pandemic virus in humans has been extremely stable. It hasn't changed at all even though people were concerned it might reassort and mix with human viruses ... but it seems that it can mix with other flu viruses (in a pig)."

Genetic research has suggested that H1N1, first identified in people in April 2009, had in fact been circulating for at least a decade and probably in pigs. Despite tight controls on herd to protect them from people, little checking is done globally to see whether food herds are infected and if so, with what viruses.

Studies in the past year have turned up pigs in Canada and other countries infected with the pandemic H1N1 virus, evidently carried to the animals by people.

"I must emphasize the point that it doesn't mean that pork is dangerous to eat at all (if well cooked). What it means is it is important to carry out systematic surveillance in pigs so we know what is going on in pigs in regard to influenza viruses in general and the pandemic virus in particular," Peiris said.

Pigs are the reservoir of many human, bird and swine viruses and experts often refer to them as an ideal mixing vessel for new, and possibly more dangerous pathogens.

Asked if there was a possibility of the H1N1 getting mixed up with the H5N1, Peiris said: "That is certainly a possibility, that's why we need to keep track.

"If it is quite able to readily reassort and pick up genes from pig viruses, you might have other combinations of genes that can arise. Unless we are alert to it, we potentially could have a virus that is ... more virulent coming back to humans."

Although H5N1 is a mostly avian virus, it causes more severe illness in people than seasonal flu and kills 60 percent of the people it infects. It has infected 499 people and killed 295 of them since re-emerging in 2003.

The World Health Organization said early in June that the H1N1 pandemic was not yet over although its most intense activity has passed in many parts of the world.

(Editing by Maggie Fox)

 
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19 more swine flu cases in West Bengal

Staff Reporter

KOLKATA: Nineteen new cases of swine flu were detected by the West Bengal Health Department on Monday. The total number of patients affected by the virus in the State has risen to 61 since July 1.

According to Dr. Asit Biswas, nodal officer of the health department's swine flu wing, condition of two of the afflicted patients is critical.

Dr. Biswas added that 21 of the 61 patients were admitted to the Beliaghata ID Hospital.

A 58-year-old cancer patient had died of the flu on July 20 marking the first death due to the A (H1NI) virus in the State.

Three national-level footballers from Sikkim and the State's Minister for Water Resources Investigation and Development are among those afflicted with the flu in the State.

The fact that is raising concern among the doctors is that none of the patients affected has any past record of travelling abroad or coming in contact with anyone who had made a foreign trip.

It has led the doctors to believe that the patients are being infected by a re-assorted strain of the A (H1N1) virus which is a mutated form of the original A (H1N1) virus and which breeds profusely during the rainy season.

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Credit goes to Jen over at the H1N1 board.
 

Another H1N1 case reported from Jaipur

TNN, Aug 7, 2010, 03.29am IST
 
JAIPUR: A 19-year-old boy tested positive for swine flu (H1N1) at SMS Hospital in the city on Friday. The teenager is a resident of Niwai, Tonk, and was living in the city’s Pratap Nagar area. He was advised the H1N1 test a couple of days ago, after he visited the hospital’s outdoor for treatment of the common cold.

The patient’s condition is said to be stable, although he has been admitted to the hospital’s isolation ward. "The patient possibly contracted the disease from one of his roommates, who reportedly tested positive for the virus during a trip to Madhya Pradesh," said Dr L C Sharma, SMS Hospital superintendent.

This the second case of H1N1 from Jaipur over the past one week — reported after a gap of nearly six months. Previously, a person had tested positive after returning from Ahmedabad. The disease has also recently resurfaced in Jodhpur and Udaipur.

The state health department has instructed its chief medical and health officers to ensure proper availability of medicines and treatment facilities at all hospitals.
 
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Nirani inspects dist hospital in wake of epidemic outbreak

TNN, Aug 8, 2010, 10.28pm IST
 
 
BIJAPUR: District minister Murugesh Nirani has instructed the health department staff to be aware of the epidemic diseases affecting people of late and take suitable measures to curb it.

After conducting a spot inspection at the district hospital here on Friday, he enquired after the health of patients.

The minister also told DHO Dr Jagannath to contact him over phone if a problem occured in the district.

Meanwhile the DHO informed that 28 cases had been reported with gastroentritis, of which one person died at Halahalli village in Indi taluk. Sixty-two cases have been reported at Sindagi taluk where two persons have died.

Sixty-seven suspected and 65 confirmed cases of chikungunya have been detected in the district while 151 dengue cases have also been reported of which one case has been confirmed.

Forty-five H1N1 cases have been suspected while 11 cases have been confirmed in the district.


Read more: Nirani inspects dist hospital in wake of epidemic outbreak - Hubli - City - The Times of India http://timesofindia.indiatimes.com/city/hubli/Nirani-inspects-dist-hospital-in-wake-of-epidemic-outbreak/articleshow/6276796.cms#ixzz0w40gnTsF
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High genetic compatibility between swine-origin H1N1 and highly pathogenic avian H5N1 influenza viruses.

Cássio Pontes Octaviani, Makoto Ozawa, Shinya Yamada, Hideo Goto, and Yoshihiro Kawaoka*

Division of Virology, Department of Microbiology and Immunology and Department of Special Pathogens, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639; ERATO Infection-Induced Host Responses Project, Japan Science and Technology Agency, Saitama 332-0012; Influenza Research Institute, Dept. of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53711; Department of Microbiology and Infectious Diseases, Kobe University, Hyogo 650-0017, Japan; and Creative Research Initiative, Sousei, Hokkaido University, Sapporo 060-0818, Japan

Abstract
Reassortment is an important mechanism for the evolution of influenza viruses. Here, we co-infected cultured cells with the pandemic swine-origin influenza virus (S-OIV) and a contemporary H5N1 virus and found that these two viruses have high genetic compatibility. Studies in human lung cell lines indicated that some reassortants had better growth kinetics than their parental viruses. We conclude that reassortment between these two viruses can occur and could create pandemic H5N1 viruses.
 

 
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Credit goes to Jen at the H1N1 board for finding this story:
 

H1N1 flu deaths revolving again in parts of Gujarat

8/8/10

Rajkot district administration distributed H1N1 vaccine to all medical and Para-medical staffs which is grounded by the state government in response to the epidemic caused recently. Saurashtra is said to be affected maximum with death of 4 out of 13 people. Now the vaccine is available for staffs in all primary health institutions in villages and cities. The vaccine is just like influenza vaccine called pandemic vaccine and is proved safe. This pandemic vaccine contains adjuvant, a substance which helps in increasing its immune response and thus making it efficient. For elder people one dose of vaccine is sufficient while for children from 6 months to 9 years 2 doses is required which has to be given in 4 weeks extension.

While H1N1 vaccine first reached British, US and UK were waiting with their orders placed. Even china was making the vaccines with 20 companies even though these companies are not related to the field. Indian government is still sleeping and not yet pre -booked any order with any of the companies like GlaxoSmithKline, Novartis etc. Even though swine flu death is increasing Indian government authorities are not taking any fruitful steps.

A senior official of Rajkot district administration says that “The vaccine will protect the staffs for 9-11 months thus putting a halo around one and shielding the person”. Thus they can treat the H1N1 patients without any precautions or fear.

When the official was questioned about the availability of vaccine for common man he says “It all depends upon the government and it is not in their hands”. The officials have also created an awareness program like ‘Wash your hands with soap now and then and eat fruits containing Vitamin C’ since soap contains carbolic acid which will kill the virus while ascorbic acid in citrus fruits will help in giving immunisation

 
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83 H1N1 deaths in India in past one week: Govt.

Submitted by admin2 on Mon, 08/09/2010 - 17:38
 
NetIndian News Network
New Delhi, August 9, 2010

As many as 83 people died of influenza A (H1N1) in India in the week ended August 8, an official statement from the Ministry of Health & Family Welfare said here today.


With this, the toll in the country since the World Health Organisation (WHO) declared the swine flu as a pandemic in mid-June last year to 1833.


Of the 83 deaths, 51 occurred in Maharashta, 12 in Karnaaka, 7 in Gujarat, 6 in Andhra Pradesh, 2 in Orissa and 1 each in Kerala, Madhya Pradesh, Goa, Uttar Pradesh and West Bengal.


A total of 942 fresh cses of the flu were reported during the week, including 400 in Maharashtra, 200 in Karnataka, 106 in Delhi and 105 in Andhra Pradesh, the statement added.

http://netindian.in/news/2010/08/09/0007407/83-h1n1-deaths-india-past-one-week-govt
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US: CDC Health Advisory for Influenza A (H3N2) virus infections
Influenza A (H3N2) virus infections have been recently detected in people in a number of states across the U.S., including two small localized outbreaks. Sporadic cases of influenza and localized summer outbreaks from seasonal influenza viruses are detected each summer.

Clinicians are reminded to consider influenza as a possible diagnosis when evaluating patients with acute respiratory illnesses, including pneumonia, even during the summer months.

    Treatment decisions should not be made on the basis of a negative rapid influenza diagnostic test result since the test has only moderate sensitivity. False positive results also can occur, particularly at times when overall influenza prevalence is low. For patients for whom laboratory confirmation is desired, or to confirm initial influenza cases in a community in which cases have been tested by rapid influenza diagnostic tests, it is recommended that reverse transcriptase polymerase chain reaction (RTPCR), and/or viral culture is utilized.

Clinicians should use empirical treatment with influenza antiviral medications for persons hospitalized with suspected influenza, and for suspected influenza infection of any severity in high-risk individuals, regardless of influenza immunization status. Early initiation of treatment provides more optimal clinical responses, although treatment of moderate, severe, or progressive disease begun after 48 hours of symptoms can still provide benefit. Continued: http://www2a.cdc.gov/han/archi...    
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4th nzer to die of H1N1 if(window.yzq_d==null)window.yzq_d=new Object(); window.yzq_d['yo8zBMtU2TY-']='&U=13heijv2r%2fN%3dyo8zBMtU2TY-%2fC%3d757199.13840550.13853413.12382107%2fD%3dLREC1%2fB%3d6060382%2fV%3d1';

A Christchurch woman is believed to be the fourth person to die of swine flu this year.

The 44-year-old, who had an underlying health condition, died last night in Christchurch Hospital's intensive care unit.

Her death has been referred to the coroner.

A 38-year-old Wellington man also succumbed to swine flu yesterday, a week after he was admitted to Wellington Hospital's intensive care unit.

He was understood to have suffered from cystic fibrosis, which affects the lungs.

The deaths follow those of a 51-year-old Northland man last month, and a 48-year-old Tauranga woman in June.

The H1N1 pandemic strain of the virus is the predominant flu strain circulating this winter.

More than 200 people have been hospitalised with swine flu this year, with nearly 60 admitted last week alone.

Ministry of Health public health director Mark Jacobs said last week regions which had not been hit hard by the virus last year were now reporting higher rates of the illness.

The Bay of Plenty, Lakes and Taranaki district health boards have reported higher swine flu hospitalisation rates than last year.

At least 35 people were confirmed to have died of swine flu last year, while more than 1000 were hospitalised.

The number of confirmed deaths could rise as coroners' findings are released.

http://nz.news.yahoo.com/a/-/top-stories/7732808/christchurch-woman-fourth-swine-flu-death/

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WHO says swine flu pandemic is over

By FRANK JORDANS (AP) – 1 hour ago

GENEVA — The World Health Organization declared the swine flu pandemic officially over Tuesday, months after many national authorities started canceling vaccine orders and shutting down telephone hot lines as the disease ebbed from the headlines.

WHO Director-General Margaret Chan said the organization's emergency committee of top flu experts advised her that the pandemic had "largely run its course" and the world is no longer in phase six — the highest influenza alert level.

"I fully agree with the committee's advice," Chan told reporters in a telephone briefing from her native Hong Kong.

The virus has now entered the "post-pandemic" phase, meaning disease activity around the world has returned to levels usually seen for seasonal influenza, she said.

But Chan cautioned against complacency, saying that even though hospitalizations and deaths have dropped sharply, countries should still keep a watchful eye for unusual patterns of infection and mutations that might render existing vaccines and antiviral drugs ineffective.

"It is likely that the virus will continue to cause serious disease in younger age groups," she said, urging high-risk groups such as pregnant women to continue seeking vaccination.

Unusually, swine flu hits young adults harder than the over-65s, who are believed to have some immunity to the A(H1N1) strain.

At least 18,449 people have died worldwide since the outbreak began in April 2009. WHO, which received at least $170 million from member states to deal with the pandemic, said last week that the true death toll is likely to be higher. But the organization's flu chief, Keiji Fukuda, said a final number won't be known for some months.

Still, lab-confirmed deaths globally increased by only about 300 in the past two months and many countries have long since closed the chapter on swine flu.

Governments in Europe and North America started dumping vaccines earlier this year after finding their stocks were full of unused and expiring supplies.

The United States stopped classifying swine flu as a public health emergency in June, while health authorities in Britain shut down their pandemic flu hot line in February and later canceled vaccine a third of vaccine orders as it became clear the pandemic strain would be less dangerous than feared. Worst-case scenarios had predicted up to 65,000 deaths in Britain. In the end there were 457 confirmed deaths from swine flu.

In Germany, authorities are meeting later this week to discuss who is going to pick up the bill for the 34 million doses of vaccines that were ordered and mostly not used.

A report by the French Senate published last month criticized WHO's handling of the pandemic, in particularly what it described as an "overestimation" of the risk and insufficient transparency about links between WHO experts and the pharmaceutical industry.

In January, polls showed 70 percent of French population thought the government overestimated the danger of the virus H1N1 and ordered too many doses of vaccine. The government had purchased 94 millions doses of vaccine, but canceled half of the initial order at the start of the year.

WHO chief Chan insisted that declaring swine flu a pandemic had been the right decision, based on the internationally agreed rules that existed at the time.

"We have been aided by pure good luck," she said, adding that if the virus had mutated then the death rate could have been much higher. In some countries as many as two in five people are now immune to swine flu, she said.

But Chan acknowledged that changes may be made to the way WHO defines pandemics. "We need to review the phases, including the severity," she said.

Prof. Angus Nicoll, flu program coordinator at the European Center for Disease Prevention and Control, said the decision to declare the pandemic over was consistent with the Stockholm-based body's recent findings.

While flu activity in the northern hemisphere is seasonally low, monitoring in southern hemisphere countries shows that few people are falling seriously ill from swine flu, said Nicoll.

Local spikes in flu deaths, such as seen recently in India, are likely due to better surveillance, he said.

Nevertheless, health officials around the world should prepare for a new type of seasonal flu to appear in the near future that will combine elements of the pandemic A(H1N1) strain, and older A(H3N2) strain and several lesser strains, said Nicoll.

"It looks sort of middle of the road at the moment," he said.

A spokesman for the U.S. Department of Health and Human Services said even though swine flu turned out milder than expected, officials have gained valuable insights into how to deal with a pandemic flu outbreak.

"The most important lesson learned from this experience is the critical need for new influenza manufacturing processes," said HHS spokesman Bill Hall.

Chan, in her exchange with journalists, also raised the specter of deadlier flu pandemics in future.

"Lurking in the background we still have H5N1," she said, a reference to the bird flu strain that has infected 503 people over seven years, killing 299.

Associated Press writers Daphne Rousseau in Paris, Kirsten Grieshaber in Berlin and AP medical writer Maria Cheng in London contributed to this report.
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Not a bad move by the WHO.  Unfortunately they feel that the avian flu pandemic threat is more serious than swine flu wave two - over the next couple of months.  You can't get the public's attention if h5 makes the jump unless you down scale the pandemic alert first and start it over. 

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Post Options Post Options   Thanks (0) Thanks(0)   Quote JustWatching Quote  Post ReplyReply Direct Link To This Post Posted: August 17 2010 at 12:15pm
Albert - you're a Scaremonger...
Disapprove


In NZ it's just those who didn't get it last year having their turn this year - although there is a fairly high rate of reinfection. I myself have had H1N1 twice now - last year was bad, this year wasn't anywhere near as bad but still put me into bed for a day. The whole family has had it - the kids didn't even really notice...


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How does that line go?  Fear....... I am fear!    Angry
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: August 18 2010 at 4:38am
India is estimating 40% of the pop will get the swine flu during their current wave.  So far 20% of the U.S. has had it.  40% could be accurate.  65 mill americans got it, maybe 120 mill more this winter?
 
Could be slightly more aggressive.  
 
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Someone needs to tell the countries in the southern hemisphere there is no second wave.
 
 
A second wave of the swine flu pandemic sweeping the country is gaining momentum and is yet to peak.

Despite the World Health Organisation declaring the world to be in a post-pandemic phase, that's not the case in New Zealand.

Some schools are reporting record absences, businesses such as hairdressers and dentists are experiencing more than usual the number of appointment cancellations, and hospitals are having higher than normal admissions, though other areas have so far been relatively untouched by the virus.

Director of public health Mark Jacobs said the uneven spread was not surprising given the prevalence of the virus last year.

"It's pretty patchy as it washes through different regions. Schools that were not hit hard last year are finding it's a different story this year."

The Wairarapa, Seddon and parts of the Waikato had been badly affected but areas such as Wellington and Gisborne were not.

At Matamata's Firth Primary School last week, seven of the school's 12 teachers and almost 20% of the pupils succumbed to the flu, while in Wairarapa, half the area's schools or training facilities had 15% or more of pupils off sick. Waikato Hospital also took the unusual step of writing to schools and child care centres informing them about the high number of viruses circulating in the community.

Jacobs said with winter viral diseases prevalent at the moment, it was inevitable children would get sick.

"Kids are the best spreaders of the flu, partly because if they haven't had it before they will catch it and partly because washing their hands thoroughly is not always the first thing on their minds," Jacobs said.

He warned that although there were "a whole lot of different regional waves of infection" it all added up to the second wave yet to peak. "In some parts of the North Island in particular it hasn't happened yet, but it will happen."

Jacobs said the good news was that by this time next year swine flu was likely to be just another seasonal flu strain. So far this year two deaths have been confirmed as being due to swine flu and about four others have been referred to the coroner for confirmation.

Vaccination against swine flu is still available and recommended for pregnant women or people with underlying health conditions.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: August 18 2010 at 9:10pm
Hey, I am getting a flu shot this year and pray there are no new changes in the H1N1. H5N1 is still very scary if it goes H2H we will be in trouble and depending on how deadly I will SIP.

Albert you never scare me you are very informative! I pay attention when you put something up to be read.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote DANNYKELLEY Quote  Post ReplyReply Direct Link To This Post Posted: August 20 2010 at 1:47pm
As do I !
WHAT TO DO????
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Flumom and DK, thanks.  It's always good to hear from my old forum friends.   If they think this is bad, people should have seen this place back in 05 - 06.     Smile
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Mary008 Quote  Post ReplyReply Direct Link To This Post Posted: August 24 2010 at 8:46am
 
we still have several Pandemics raging in the world...
 
 
Sentido.tv :: Health :: Malaria Pandemic Kills 2 Million Per Year
MALARIA PANDEMIC KILLS 2 MILLION PER YEAR 24 June 2004. Anti-malaria activist and missionary groups report malaria is world's unseen pandemic, ...
www.casavaria.com/sentido/science/.../04-0624-Malaria.htm - Cached - Similar
 
 
 
 
Tuberculosis Pandemic Information | Pandemic Help Online
Aug 17, 2010 - Information is crucial when you are looking to purchase Tuberculosis Pandemic. Don.
www.pandemic-help-online.com/...Pandemic/Tuberculosis-Pandemic - Cached
 
 
 
 
JAMA -- Controlling and Ultimately Ending the HIV/AIDS Pandemic: A ...
by GK Folkers - 2010
Jul 21, 2010 ... JAMA is a highly cited weekly medical journal that publishes peer-reviewed original medical research findings and editorial opinion.
jama.ama-assn.org/cgi/content/extract/304/3/350
 
 
Water tanks spark dengue pandemic fears - ABC News (Australian ...
Feb 19, 2010 - There is growing concern rainwater tanks are fuelling a mosquito problem, potentially helping to spread the mosquito-borne dengue virus around Australia.
www.abc.net.au/news/stories/2010/02/19/2825202.htm - Cached - Similar
 
 
 
..................
 
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote DANNYKELLEY Quote  Post ReplyReply Direct Link To This Post Posted: August 24 2010 at 12:50pm
I liked 05 and 06Thumbs%20Up
WHAT TO DO????
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Penham Quote  Post ReplyReply Direct Link To This Post Posted: August 26 2010 at 6:18pm
Scaremonger????  I think not! It's all just information.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote JustWatching Quote  Post ReplyReply Direct Link To This Post Posted: August 26 2010 at 10:49pm
Mmmm...  time for a little touch of reality me thinks....

Last year was something to be worried about - we were playing with an unknown and we were VERY near to the countries (advanced and good) health system collapsing - this year however we know what to expect and even while the virus has mutated it's still nothing to freak about.

The below are the most recent consultation rates for influenza-like illness in New Zealand - with the blue line being this year.

As you can see - this year we are peaking WELL before we get anywhere near last years peak...

Last year it knocked something like 35 of us Kiwis off - so far this year we are around 15... even if we were to multiply those number by a factor of 10 they are still a LONG way short of other causes of death in this country - like the annual road toll for example.



One thing which I do think is worth noting however is this: I am currently sick again, have spent the last day in bed. I have all the signs of H1N1 again and I'm pretty certain that's what I've got (there's bugger all else down this way to catch at the moment!).

If that's the case then this is the 3rd time I have had this bug - which would mean the rate of reinfection is VERY high (I'm healthy 35 year old male).

I know there has being a mutation picked up down the line a little way - the introduction of
D225G/N - perhaps that has helped increase the rate of reinfection...  I'm unsure.

But one thing I do know - H1N1 WAS a near miss. Our reaction in the online community at the time was great and websites just like this one were invaluable in spreading information over and beyond the bull****ting media and governments - however the event is past now, you can lower your pretty little graphic up in the top right down to POST Pandemic and we can all sit back and enjoy life again...

So all and all - well done "AvianFluTalk" - and thank you.

See you next time...  which I have no doubt will be sometime soon enough.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote rickster58 Quote  Post ReplyReply Direct Link To This Post Posted: September 08 2010 at 2:56am
Hi Albert and gang,
 
Nothing new to report here in Australia as yet. The current wave sweeping NZ does not seem to have made its way across here. Mind you, we have had a very mild, flu season this year, with almost zero h1n1 reported  through the media (not that you can judge by that these days).
 
Will keep ya posted.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote JustWatching Quote  Post ReplyReply Direct Link To This Post Posted: September 08 2010 at 12:35pm


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Post Options Post Options   Thanks (0) Thanks(0)   Quote JustWatching Quote  Post ReplyReply Direct Link To This Post Posted: September 08 2010 at 12:36pm

Pandemic Influenza H1N1 2009 (swine flu) - Update 206


Influenza H1N1 activity reports are continuing to show a decline.

The number of influenza calls to Healthline is back to normal - currently at the same rate as in 2008 - the year before the pandemic. Though the picture is complicated by the Christchurch earthquake which has bumped up the number of calls to Healthline overall.

Since last Thursday's update, there has been one additional death linked to swine flu reported. This brings the total to date to 17. Thirteen of these deaths have so far been confirmed as being due to swine flu. Details of the latest death is reported on the Auckland DHB website.

As at midday today, there have been 648 hospitalisations of laboratory-confirmed cases of pandemic influenza H1N1, including 11 people currently in intensive care. So far this year, a total of 103 people with confirmed H1N1 have been admitted to intensive care. These figures do not include influenza-like illness among people admitted to hospital without a positive H1N1 laboratory test result.

It's important to seek medical advice early, particularly for people with underlying medical conditions or who are severely overweight or pregnant as they are at greater risk of a more severe illness. If you have flu-like symptoms, phone your GP first before you go in to help them manage your care and prevent spread to others. For health advice, call Healthline on 0800 611 116.

http://www.moh.govt.nz/moh.nsf/indexmh/influenza-a-h1n1-update-206-060910
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