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PANDEMIC ALERT LEVEL
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Tracking the next pandemic: Avian Flu Talk

WHO H7N9 Situation updates

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Albert View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: January 30 2014 at 7:07pm
This could get ugly with the Lunar New Year.  The poultry markets will explode with sales and people, not to mention limited h2h.
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: January 30 2014 at 9:23pm
Suzi - Hong Kong found it in poultry from Guangdong, but China says it's not there. Someone's lying Unhappy
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"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote CRS, DrPH Quote  Post ReplyReply Direct Link To This Post Posted: January 30 2014 at 11:46pm
Originally posted by jacksdad jacksdad wrote:

Suzi - Hong Kong found it in poultry from Guangdong, but China says it's not there. Someone's lying Unhappy

Ummm...China?  

Just guessing.   You've probably seen Osterholm's latest:


Dave Halvorson, DVM, an avian health expert at the University of Minnesota in St. Paul, told CIDRAP News that media reports describing China’s poultry testing techniques raise questions about their effectiveness.

He said a ProMED Mail post on a recent report from China’s agriculture ministry to the World Organization for Animal Health (OIE) suggests that Chinese scientists are using polymerase chain reaction and viral isolation testing to monitor poultry. ProMED Mail is the Internet reporting service of the International Society for Infectious Diseases.

He said the surveillance method they are using has little value, because the low-pathogenic virus causes few if any signs in poultry. "It's akin to looking for human influenza virus by sampling clinically healthy people—you won't find much virus."

"I call this type of surveillance '‘looking for negatives,' because the probability of finding virus in healthy birds is so low," Halvorson said.

(see no evil, hear no evil I guess.)

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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 1:06am
Originally posted by CRS, DrPH CRS, DrPH wrote:

"I call this type of surveillance '‘looking for negatives,' because the probability of finding virus in healthy birds is so low," Halvorson said.


I think that just about sums up the situation. Hoping that nobody is really paying close attention, China is doing a half-assed job of making it look like they're responsible and diligent, while their motives are actually much more self serving. After losing billions in poultry sales last year, they're desperate to put a positive spin on this, as evidenced by these quotes from the same CIDRAP article,

"...Meanwhile, China's agriculture ministry said today that tests on farms so far this year have found no H7N9 in poultry, according to a separate report from Xinhua. It said no positives were found among 33,400 samples tested from 2,402 sites...."

"...Fueling more questions about H7N9 circulation on China's poultry farms, Hong Kong's government today said it detected the virus in a number of samples from a shipment of live chickens that were imported from a registered poultry farm near the Guangdong province city of Foshan, according to a statement posted on the government's Web site..."

So, while mainland China openly admits that the virus is showing up in poultry at live markets and sickening people, they flatly deny that the infected birds are coming from their poultry farms. Can't argue with logic like that... Wacko




"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 5:22am

I've said this before, but it could be worth repeating.  SARS spread internationally and left China at around 300 cases.  Both h7 and SARS had/have similar limited h2h.   Based on history, h7 will probably do the same within about 30 days. 

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Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 7:41am
Originally posted by Albert Albert wrote:

I've said this before, but it could be worth repeating.  SARS spread internationally and left China at around 300 cases.  Both h7 and SARS had/have similar limited h2h.   Based on history, h7 will probably do the same within about 30 days. 



Dr.Tom Frieden agrees with you!

"Today marks the Lunar New Year – and the world’s largest annual migration. There will be more than 3.6 billion transit trips within China, in addition to countless international trips. Yet this celebration comes at a time of growing concern about the H7N9 avian influenza virus. And this concern is not unfounded – should this virus change into a form that easily spreads between people, the world’s next pandemic could occur in the next three weeks."

Part of an article from CNN

http://globalpublicsquare.blogs.cnn.com/2014/01/31/how-to-prevent-the-next-pandemic/?hpt=hp_bn2
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 8:35am
think i might have to start Prepin......lol
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Waterboy Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 8:40am
Yes I agree. It may be time...
Family is the toughest part here. They don't believe a pandemic could happen to them. Atleast my family.Any ideas on how I can educate them on this potential problem?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote CRS, DrPH Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 9:29am
Originally posted by carbon20 carbon20 wrote:

think i might have to start Prepin......lol

Absolutely!  When the major public health agencies in the USA start to gear up for pandemic training, you know that the brains in the field are gettin' worried. 

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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 12:02pm
Originally posted by Waterboy Waterboy wrote:

Yes I agree. It may be time...
Family is the toughest part here. They don't believe a pandemic could happen to them. Atleast my family.Any ideas on how I can educate them on this potential problem?


I'm willing to bet that most of us are in the same position - my wife tolerates my prepping (not sure she would if she knew the extent though) but she's openly skeptical about there being any real need for it. I prep for the time when it's too late to head to the store because panic buying has stripped the shelves, and I can do that myself without help. When the time comes, they'll see the wisdom in what we do
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 2:51pm
i dont prep as such ,my belief is that if the "slate wiper " hit and with luck me and mine survive, after

 3/4 weeks  there wont be many people left.......

i have a 'BUG OUT' plan/place to go away from the populated areas

 i do worry what to do about the animals in the Zoo?

prob.  have to leave them to die...........

there would be some hard times ,doubt if most peoples head's would cope with the reality

Vermin would take over ,there  would be rats by the millions and  Roaches, wild cats and dogs ,scavaging

 on the dead,

i think alot of survivor's would go mad

so glad i live here in the most isolated city on the planet

one road in and 4,000 kms  to the next nearest city across a desert

only 2million people live in the whole of Western Australia
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Kyle Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 4:20pm
Lucky you, I live in urban Denver. Can't even imagine the chaos that would ensue in a city.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 7:56pm
Kyle, Denver will get bad I live in the outer burbs and I am armed to the teeth but...I think about just laying low making my house look like it was burned out and boarded up. NO one is in good shape. When I read that book about the Argentina guy he talks about people in their "bug out houses" and how people like that were tortured, raped, and killed.

It will be the luck of the draw for all of us no matter where we are!
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Originally posted by FluMom FluMom wrote:

Kyle, Denver will get bad I live in the outer burbs and I am armed to the teeth but...I think about just laying low making my house look like it was burned out and boarded up. NO one is in good shape. When I read that book about the Argentina guy he talks about people in their "bug out houses" and how people like that were tortured, raped, and killed.

It will be the luck of the draw for all of us no matter where we are!


Really so you feel population density and proximity to that population density won't play a major survival factor in the event of social breakdown due to a virus, ect huh. How interesting. I think its dangerous to rely on luck, since you never get to choose when or if it applies to you.   
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: January 31 2014 at 9:46pm
i think its a few things that will play a role , depends on the severity of the pandemic..

worst case the 'slate wiper' 97% of the population die

add to that death from  other causes,

you might have all the preps you can ,and die in the first week,

depends on the incubation period  of virus

and if you were watching events through a site like this

for warned is forarmed

BE AWARE !!!!!!

MIGHT SAVE  YOU AND YOURS ......


Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

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Post Options Post Options   Thanks (1) Thanks(1)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 9:52am
Originally posted by carbon20 carbon20 wrote:

i dont prep as such ,my belief is that if the "slate wiper " hit and with luck me and mine survive, after
3/4 weeks  there wont be many people left.......


Carbon - sorry, but I couldn't disagree more. You have to prep, buddy.

There is no flu outbreak  that could possibly result in most of the population dying. We're all unique, and our genetic diversity means that at most, only about 50% of us are susceptible to any given influenza virus. 30% is likely the highest infection rate possible for a pandemic influenza strain - still devastating if a virus has a high CFR, but certainly not capable of killing most of our species. Viruses typically trade off lethality for human transmission, so H7N9's current 20% CFR would drop even more in a pandemic. A 30% infection rate, with less than 20% of those dying is still a huge number, but not a slate wiper on it's own.

No virus - not even something as infectious as influenza - could take the world by surprise and sicken and kill that many people in so short a time. If things got really bad and panic set in (think bodies in the streets bad) voluntary social distancing would slow down transmission of the virus. People would avoid contact, stay home from work and SIP if they could. It wouldn't necessarily guarantee staying disease free because the majority would be non-preppers who would still have to go looking for supplies, but it would slow it's spread making a 3 to 4 week time frame all but impossible.

When I first started prepping, I read a couple of good articles that scared the bejeezus out of me. Actually, they were probably the reasons I started down this road because of the concise way they laid out the consequences to society of a major pandemic, particularly the timeline of an outbreak, the effect that absenteeism and fatalities would have on supply lines and infrastructures, and the very real need for self sufficiency. Both were written a few years ago (back when H5N1 was the only one that had us worried) and should be viewed in that context, but the societal effects they discuss are relevant to any strain that might go H2H in a big way. I'll include a link here for Grattan Woodson's article. The other is hard to find on a site that's not blocked, but it's available as a pdf file called "Becoming self sufficient for six months" by a guy that goes by the title Dr. Dave. Google it and you should find it.

Carbon - you're a valued member here. Please rethink your strategy and stay safe.


http://www.fluwiki.info/uploads/Consequences/NewGuideOct7b.pdf
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"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (1) Thanks(1)   Quote Satori Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 10:25am

EXcellent post Jacksdad


"prepping" is insurance

that's how I think of it

I don't ever want to have to use it

but IF I need it

it is there


I've posted this before

but it bears repeating

If 3 Inches Of Snow Can Cause This Much Chaos In Atlanta, What Will Economic Collapse Look Like?

http://endoftheamericandream.com/archives/if-3-inches-of-snow-can-cause-this-much-chaos-in-atlanta-what-will-economic-collapse-look-like


excerpt



Well, according to a report put out by the American Trucker Associations entitled “When Trucks Stop, America Stops“, life would get “apocalyptic” quite rapidly…

A Timeline Showing the Deterioration of Major Industries Following a Truck Stoppage

The first 24 hours

• Delivery of medical supplies to the affected area will cease.
• Hospitals will run out of basic supplies such as syringes and catheters within hours. Radiopharmaceuticals will deteriorate and become unusable.
• Service stations will begin to run out of fuel.
• Manufacturers using just-in-time manufacturing will develop component shortages.
• U.S. mail and other package delivery will cease.

Within one day

• Food shortages will begin to develop.
• Automobile fuel availability and delivery will dwindle, leading to skyrocketing prices and long lines at the gas pumps.
• Without manufacturing components and trucks for product delivery,
assembly lines will shut down, putting thousands out of work.

Within two to three days

• Food shortages will escalate, especially in the face of hoarding and consumer panic.
• Supplies of essentials—such as bottled water, powdered milk, and
canned meat—at major retailers will disappear.
• ATMs will run out of cash and banks will be unable to process
transactions.
• Service stations will completely run out of fuel for autos and trucks.
• Garbage will start piling up in urban and suburban areas.
• Container ships will sit idle in ports and rail transport will be disrupted, eventually coming to a standstill.

Within a week

• Automobile travel will cease due to the lack of fuel. Without autos and busses, many people will not be able to get to work, shop for groceries, or access medical care.
• Hospitals will begin to exhaust oxygen supplies.

Within two weeks

• The nation’s clean water supply will begin to run dry.

Within four weeks

• The nation will exhaust its clean water supply and water will be safe for drinking only after boiling. As a result gastrointestinal illnesses will increase, further taxing an already weakened health care system.

This timeline presents only the primary effects of a freeze on truck travel. Secondary effects must be considered as well, such as inability to maintain telecommunications service, reduced law enforcement, increased crime, increased illness and injury, higher death rates, and likely, civil unrest.


and unfortunately

most Americans aren't prepared for much of anything


Not Prepared: 17 Signs That Most Americans Will Be Wiped Out By The Coming Economic Collapse

http://theeconomiccollapseblog.com/archives/not-prepared-17-signs-that-most-americans-will-be-wiped-out-by-the-coming-economic-collapse


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Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 11:14am
jacksdad- I agree with you if it's a natural virus, man made is another story!

Satori- Great post! During our last ice storm trucks were at a stand still and the stores were bare in two days.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote KiwiMum Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 11:43am
The driving force for our family is the overdue huge earthquake from the Alpine Fault. When that happens, the whole of the South Island of New Zealand will cease to function.

When we had a local 7.1 earthquake in Sept 2010 at 4.35am, I drove down to town at about 9am out of curiosity. I wanted to see what was happening at the supermarkets. Both were shut, due to smashed produce all over the floors but the manager of one told me she would open at 10am, so I waited. I parked near the entrance of the carpark and went and sat by the door and watched. 

Within a few minutes it was madness. People from Christchurch (our local city where the epicentre was) started arriving in cars and cruising around the carpark and then driving off looking for somewhere open, then they came back and a queue started. People were frightened. I was at the front of the queue. 

The doors opened at 10 am and since I was first in I thought I'd stock up on wine and maybe a bit more pasta, but mainly wine. it was mayhem. I didn't linger, I just took my cart to the checkout. Already there were people shouting at the staff. The manager had imposed a limit on bread and water per person but within half an hour, there was none left. It was 2 bottles per person. I bought 2 and gave them to someone else in the carpark (since we have huge water reserves).

People were shoving each other, the atmostphere was incredible. The staff were very stresses and I saw one checkout lady in tears. They could only take cash or cheques. The man in front of me bought 1 packet of nappies (diapers) and cigarettes because that's all the money he had.

After I left I heard that the supermarket shut late morning because of the people. Now that is just what happened in our small town after one earthquake that didn't even kill anyone. It was a knee jerk panicked reaction.

In Feb 2011 we had a 6.3 that killed 181 people (it was very shallow and ground acceleration bought down hundreds of buildings). After that quake the whole of the CBD in Christchurch was cordoned off and remained so for about 2 years. Food sat on the tables in restaurants, rotting in fridges, kitchens etc. With the absence of normal life, rats flourished. In fact the rat population exploded and the rats grew to enormous size feasting on rotting remains. 

Even now, 3 years later only 50% of the underground pipes have been repaired. People living in Chch had no water, sewerage or power. Now this all happened locally and help arrived from all over the globe and from all over NZ. Our community shipped in water to houses in town. We all washed out bottles and milk cartons and filled them from our clean supplies, we donated blankets and spare food. 

Imagine if a disaster happens that's national, where will the help come from? A pandemic that leaves people too scared to go to work will paralyse society. No water, no sewerage, no power, no transport, no food. 

Everyone has something that they can prepare for. You need cash on hand, water, food, lighting, fuel plus a hundred other things. One thing's for sure, after the big 8.2 that's predicted, I won't venture out. We'll stay put. When the big one comes there will be real hardship here.
Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Kyle Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 12:05pm
Back in 2005 we had a massive snowstorm that left over 2 feet of snow here and in the city. Snow plows couldn't keep up and it got to a point where it was impossible to leave our home. Luckily my parents had a lot of extra food, water, etc but if it were to last a few more days we would have  been forced without food.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 1:33pm
I've mentioned this before, but I was in the SoCal blackout and even though it only lasted about 12 hours in the worst affected areas, what I saw still managed to shake my faith in people's priorities. It happened late in the afternoon, and the timing made all the difference.
I learned a valuable lesson myself that day because both of our vehicles were low on gas and I had nothing stored in cans. I picked up my wife (45 minutes in traffic on a route that normally takes five), but we had to pull over on the way back and wait for the congestion to clear or risking running out of fuel. The gas stations we passed were bumper to bumper with cars, drivers standing dejectedly next to their vehicles, probably unable to get home. We parked in the shade outside a liquor store, and for an hour we watched a constant stream of people pull up, look through the darkened windows, bargain unsuccessfully with the staff seated outside in chairs and leave. KiwiMum - you have plenty of everything, but I guarantee that most of these people had no food, water or batteries stockpiled. Booze was the last thing they should have been hunting down in the hours before it got dark.
And it got dark. It was like being out in the mountains or desert on a moonless night. We had area lamps and flashlights in abundance, and an emergency radio for updates on the few stations we could find still able to broadcast. The streets and houses were pitch black though, with the exception of maybe one house per block with a single candle lighting up a room. People were bending down and using cellphones to light their way as they walked home. It was sad, and very disturbing to contemplate what the second night would have been like if the power hadn't come back on. And the chaos that would have ensued by the end of the first week doesn't bear thinking about.
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"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 1:39pm
Originally posted by arirish arirish wrote:

jacksdad- I agree with you if it's a natural virus, man made is another story



Captain Trips? Wink
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 2:16pm
i live 5 mins from the ocean, rabbits and kangaroos ,sheep and cattle all nearbye for fresh food ,i am an

experienced out doors person ,believe me when i say, i know my capablities to think on my feet,i can

make drinking water out of the lakes around where i live ,i have tins of fish ,potatoes ,veggies

 i have dried milk powder(full fat) ,rice and flour and pasta,

i dont store shelves of toilet paper, as i have seen other prepers do on the TV,


i dont need a weapon!!!!!

Perth is a very special place to live ,

the Austalian people will all pull together in a crisis,

i am a member of the local State Emergency Service,

i know how to make it through if the  going gets tough,

might boost up the supplies the moment i hear H2H confirmed !!!!!!

5 P's ........prior preperation prevents poor perfomance

think this site is great ,and you all good people on here glad to be with you Wink
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 2:21pm
funny Niman not on this at all he more interested in h1n1 and h5n1 ????????
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Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 2:28pm
jacksdad- I had to Goggle it, I've never read Stephen King! I don't know about 90% but I believe sooner or later there will be a GoF lab accident or some terrorist will let something loose that we've never seen before!   
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 2:49pm

Human Cytotoxic T Lymphocytes Directed to Seasonal Influenza A Viruses Cross-React with the Newly Emerging H7N9 Virus

  1. Guus F. Rimmelzwaana,b

+ Author Affiliations

  1. aViroscience Laboratory, Erasmus MC, Rotterdam, The Netherlands
  2. bViroClinics Biosciences BV, Rotterdam, The Netherlands

ABSTRACT

In February 2013, zoonotic transmission of a novel influenza A virus of the H7N9 subtype was reported in China. Although at present no sustained human-to-human transmission has been reported, a pandemic outbreak of this H7N9 virus is feared. Since neutralizing antibodies to the hemagglutinin (HA) globular head domain of the virus are virtually absent in the human population, there is interest in identifying other correlates of protection, such as cross-reactive CD8+ T cells (cytotoxic T lymphocytes [CTLs]) elicited during seasonal influenza A virus infections. These virus-specific CD8+ T cells are known to recognize conserved internal proteins of influenza A viruses predominantly, but it is unknown to what extent they cross-react with the newly emerging H7N9 virus. Here, we assessed the cross-reactivity of seasonal H3N2 and H1N1 and pandemic H1N1 influenza A virus-specific polyclonal CD8+ T cells, obtained from HLA-typed study subjects, with the novel H7N9 virus. The cross-reactivity of CD8+ T cells to H7N9 variants of known influenza A virus epitopes and H7N9 virus-infected cells was determined by their gamma interferon (IFN-γ) response and lytic activity. It was concluded that, apart from recognition of individual H7N9 variant epitopes, CD8+ T cells to seasonal influenza viruses display considerable cross-reactivity with the novel H7N9 virus. The presence of these cross-reactive CD8+ T cells may afford some protection against infection with the new virus.

Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 3:10pm
the best read ,i read this about 20 years ago ,this is where i first heard about the 'slate wiper'97%
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Is this recent?
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I mean the abstract previously posted. Is it recent?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 3:40pm
yes  november 2013 Google scholar,scary


Human Cytotoxic T Lymphocytes Directed to Seasonal Influenza A Viruses Cross-React with the Newly Emerging H7N9 Virus

  1. Guus F. Rimmelzwaana,b

+ Author Affiliations

  1. aViroscience Laboratory, Erasmus MC, Rotterdam, The Netherlands
  2. bViroClinics Biosciences BV, Rotterdam, The Netherlands

ABSTRACT

In February 2013, zoonotic transmission of a novel influenza A virus of the H7N9 subtype was reported in China. Although at present no sustained human-to-human transmission has been reported, a pandemic outbreak of this H7N9 virus is feared. Since neutralizing antibodies to the hemagglutinin (HA) globular head domain of the virus are virtually absent in the human population, there is interest in identifying other correlates of protection, such as cross-reactive CD8+ T cells (cytotoxic T lymphocytes [CTLs]) elicited during seasonal influenza A virus infections. These virus-specific CD8+ T cells are known to recognize conserved internal proteins of influenza A viruses predominantly, but it is unknown to what extent they cross-react with the newly emerging H7N9 virus. Here, we assessed the cross-reactivity of seasonal H3N2 and H1N1 and pandemic H1N1 influenza A virus-specific polyclonal CD8+ T cells, obtained from HLA-typed study subjects, with the novel H7N9 virus. The cross-reactivity of CD8+ T cells to H7N9 variants of known influenza A virus epitopes and H7N9 virus-infected cells was determined by their gamma interferon (IFN-γ) response and lytic activity. It was concluded that, apart from recognition of individual H7N9 variant epitopes, CD8+ T cells to seasonal influenza viruses display considerable cross-reactivity with the novel H7N9 virus. The presence of these cross-reactive CD8+ T cells may afford some protection against infection with the new virus.

FOOTNOTES

    • Received 27 September 2013.
    • Accepted 12 November 2013.
  • Address correspondence to Guus F. Rimmelzwaan, g.rimmelzwaan@erasmusmc.nl.
  • * Present address: Marine L. B. Hillaire, CIRI, INSERM U1111, Lyon, France.

  • C.E.V.D.S. and J.H.C.M.K. contributed equally to this work.

  • Published ahead of print 20 November 2013


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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 4:13pm
Originally posted by arirish arirish wrote:

jacksdad- I had to Goggle it, I've never read Stephen King! I don't know about 90% but I believe sooner or later there will be a GoF lab accident or some terrorist will let something loose that we've never seen before!   


Arirish - do yourself a favor and get a copy of "The Stand", and definitely take the time to find the much longer unabridged version. When he first wrote it, Stephen King didn't have as much clout with his publishers as he does now, and they cut almost half of it (something like 500 pages). Thankfully the original is now in print again. It's a long read, but you'll still wish it was longer.

Absolutely awesome novel Thumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs UpThumbs Up
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"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Suzi Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 4:43pm
Demon in the Freezer is good also. About small pox.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote KiwiMum Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 4:51pm
Is The Stand a horror story? I read some Stephen King when I was at college and it was really frightening. I'm not sure I could read another horror story. I love thrillers, just not horror. 
Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 4:59pm
The Stand is a Story " Hot Zone" is real life ,another good story is "the earth abides"

Earth Abides
great read
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Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 5:36pm
I read all the time, mostly history and mysterys but I love all books so I'll give all of the above a try! Thanks for the recommendations!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote hachiban08 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 5:55pm
I still really like One Second After (it's about an EMP attack and the aftermath of it). Has a slight dystopian feel to me, and that's the genre I read the most/working on a novel about.



Be prepared! It may be time....^_^v
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Yes Looper luck will be a big part of survival. I don't know about you but I am not wealthy enough to have a second retreat. Many of us do not have that kind of money. And what? You take off from your home during a pandemic or some other event with thousands and try and take over some other persons retreat out of the city?

No matter where you SIP there will be someone who will try and take what you have.

Now if you have a fully functioning underground retreat that does not need for you to ever come out of the hole then you are both very lucky and very wealthy.

Then you have to look at how old you are and your physical condition. I am in my mid 60's with a kid in college. I have a "bad" ankle that I hurt in my 30's and I do therapy for it but it is a big weakness. So a very long walk especially on uneven ground is not a good thing.

My husband died in 5 years ago so no man to help... makes a huge difference. Men have skills and strengths that most women do not have. And my 20 year old son does not make a man...yet!

I will be lucky depending on the disaster on getting my kid home from college and hunker down at home. So yes, luck will play a big part on survival for many of us.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 7:35pm
I don't want to ruffle any feathers (excuse the pun) and I apologize if I do but thought this thread was WHO H7N9 Situation Updates. I kinda of expect the info here to br relevant to this topic as well as being current to our situation today. Logging on and finding info that is very dated, while interesting and valuable, as well as book reviews and opinions on prepping aren't what I think most would be looking for in this post. Of course I defer to those who have been here a long time and built this helpful site
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 7:54pm
we do get side tracked dont we LOL,

anyway h7n9 is very scary ,noting that we humans have no  resistance to it........aka  a  few posts ago
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: February 01 2014 at 9:14pm
We did go a bit OT there, didn't we? Don't worry - we'll probably get someone to start a new WHO update thread and this one will sink into obscurity. Unlike some forums, AFT has never been particularly rules orientated in that respect and some of us have a habit of losing track and getting easily sidetracked... Ermm
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6 new cases in China, 1 dead.
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Originally posted by FluMom FluMom wrote:

Yes Looper luck will be a big part of survival. I don't know about you but I am not wealthy enough to have a second retreat. Many of us do not have that kind of money. And what? You take off from your home during a pandemic or some other event with thousands and try and take over some other persons retreat out of the city?

No matter where you SIP there will be someone who will try and take what you have.

Now if you have a fully functioning underground retreat that does not need for you to ever come out of the hole then you are both very lucky and very wealthy.

Then you have to look at how old you are and your physical condition. I am in my mid 60's with a kid in college. I have a "bad" ankle that I hurt in my 30's and I do therapy for it but it is a big weakness. So a very long walk especially on uneven ground is not a good thing.

My husband died in 5 years ago so no man to help... makes a huge difference. Men have skills and strengths that most women do not have. And my 20 year old son does not make a man...yet!

I will be lucky depending on the disaster on getting my kid home from college and hunker down at home. So yes, luck will play a big part on survival for many of us.


I hear you Flumom no doubt everyone will do the best they can in the event of a major situation and never was it said that good luck was not a good thing.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Newbie Quote  Post ReplyReply Direct Link To This Post Posted: February 02 2014 at 5:59am
Originally posted by FluMom FluMom wrote:



Then you have to look at how old you are and your physical condition. I am in my mid 60's with a kid in college. I have a "bad" ankle that I hurt in my 30's and I do therapy for it but it is a big weakness. So a very long walk especially on uneven ground is not a good thing.

My husband died in 5 years ago so no man to help... makes a huge difference. Men have skills and strengths that most women do not have. And my 20 year old son does not make a man...yet!

I will be lucky depending on the disaster on getting my kid home from college and hunker down at home. So yes, luck will play a big part on survival for many of us.


Wow, can I relate! Younger (45) and healthy but also no man & keeping farm going with 'power on' and everything being so called normal is hard enough!! You are so right in that men have different skills - I can do some wood work, but am absolutely useless when it comes to anything mechanical!!!   
I do have family close by - one thinks he's ready, but also thinks what coming 'isn't a big deal...'! No concept of how ugly this can/will get - and by this I mean grid down as it seems like all worst case scenarios - terrorist attack, EMP, plague, massive natural disaster etc all eventually hit society break down & power outage... One thing that never seems to get touched on is the fact that if grid down occurs for any real duration of time - the us has 100+ nuclear power plants that all have the potential to turn into Fukushima!!!! To try to survive that WILL need an under ground bunker & in that regard I'm also the same as you (& most ppl) ...who has $!!'s for that?!?!?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: February 02 2014 at 6:08am
A seasonal spike in bird flu cases in China has left 18 people dead, after at least 95 confirmed cases.
Source
AAP

Twelve people have been killed by H7N9 bird flu in a single Chinese province this month, according to state media.

The deaths occurred in the eastern province of Zhejiang, the state-run Xinhua news agency said, citing local health authorities.

The report came as China was said to have dropped its previous description of H7N9 bird flu as "infectious" in new guidelines on how to deal with the disease.

The National Health and Family Planning Commission described it as a "communicable acute respiratory disease" in its 2014 diagnosis and treatment protocols.

In the 2013 version it was considered an "infectious disease".

The Beijing Times on Monday quoted an unnamed Beijing disease control centre official saying that health authorities decided to "downgrade" the virus on the basis that nearly a year of analysis had shown H7N9 was "not strongly infectious".

The H7N9 human outbreak began in China in February 2013 and reignited fears that a bird flu virus could mutate to become easily transmissible between people, potentially triggering a pandemic.

The guidelines come as human cases undergo a seasonal spike, with at least 95 cases confirmed in mainland China so far this month, leading to 18 deaths, according to an AFP tally of reports.

More than half have been in Zhejiang, with 24 in Guangdong in the south.

That compares with 144 confirmed cases, including 46 deaths, in the whole of 2013 according to official statistics.

It was not clear whether the rise in reported cases is due to the virus becoming more widespread and possibly less severe, or detection and treatment improving.

Cases and deaths dropped significantly after the end of June, but have begun to pick up with the onset of winter.

"So far, most cases have been sporadic and there were some cluster outbreaks among family members," the commission said in the guidelines.

"But there is no evidence of sustained human-to-human transmission yet," it said, although it added that "limited" and "unsustained" infections could not be ruled out.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Kyle Quote  Post ReplyReply Direct Link To This Post Posted: February 03 2014 at 5:24pm
Human infection with avian influenza A(H7N9) virus – update

Disease outbreak news

3 FEBRUARY 2014 - The National Health and Family Planning Commission (NHFPC) of China has notified WHO of nine additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus, including one death.

Details of four cases notified on 1 February 2014 are as follows:

All four cases are male. The age range is 5 to 80 years old. Cases have been reported from Guangdong (2), and Zhejiang (2). Two cases are currently in critical condition and the other two cases are in stable condition. Three of the cases are reported to have had exposure to poultry or a live poultry market.

A 80-year-old man from Hangzhou City, Zhejiang Province, who became ill on 19 January and was admitted to hospital on 30 January. He is currently in a critical condition. The patient has a history of exposure to live poultry.

A 54-year-old man from Hangzhou City, Zhejiang Province, who became ill on 23 January and was admitted to hospital on 26 January. He is currently in a critical condition.

A 6-year-old boy who is living in Shenzhen City, Guangdong Province, and became ill on 27 January. He was detected on 28 January by Shenzhen Entry-Exit Quarantine Bureau when travelling through Huanggang Port. He has mild symptoms and is in a stable condition. He is currently in isolated treatment at home. The patient has a history of exposure to live poultry.

A 5-year old boy from Zhaoqing City, Guangdong Province, who became ill on 29 January and admitted to hospital on the same day. He is in a stable condition. The patient has a history of exposure to a live poultry market.

Details of five cases notified on 31 January 2014 are as follows:

Of these, four cases are male. The age range is 28 to 82 years old. Cases have been reported from Guangdong (4), and Hunan (1). One case is fatal and the rest are currently in critical or serious condition. Four of the cases are reported to have had exposure to poultry or a live poultry market.

A 28-year-old man from Zhaoqing City, Guangdong Province, who became ill on 24 January 2014 and admitted to hospital on 26 January. He is currently in a critical condition. The patient has a history of exposure to a live poultry market.

A 82-year-old man from Foshan City, Guangdong Province, who became ill on 22 January and admitted to hospital on 26 January. He is currently in a critical condition.

A 59-year-old man from Guangzhou City, Guangdong Province, who became ill on 22 January and admitted to hospital on 26 January. He died on 30 January. The patient had a history of exposure to a live poultry market.

A 81-year-old woman from Shenzhen City, Guangdong Province, who became ill on 25 January and admitted to hospital on 29 January. She is currently in a serious condition. The patient has a history of exposure to a live poultry market.

A 38-year-old male from Yongzhou City, Hunan Province with onset of symptoms on 24 January 2014. He was admitted to hospital on 30 January and is currently in a critical condition. The patient has a history of exposure to a live poultry market.

So far, there is no evidence of sustained human-to-human transmission.

The Chinese Government continues to take the following surveillance and control measures:

strengthen surveillance and situation analysis;
reinforce case management and treatment;
conduct risk communication with the public and release information;
strengthen international collaboration and communication; and
conduct scientific studies.

Sporadic human cases

While the recent report of avian influenza A(H7N9) virus being detected in live poultry imported from the mainland to Hong Kong SAR, shows the potential for the virus to spread through live poultry, at this time there is no indication that international spread of avian influenza A(H7N9) has occurred through humans or animals.

Further sporadic human cases of A(H7N9) infection are expected in affected and possibly neighbouring areas, especially given expected increases in the trade and transport of poultry associated with the Lunar New Year.

WHO advice

WHO advises that travellers to countries with known outbreaks of avian influenza should avoid poultry farms, or contact with animals in live bird markets, or entering areas where poultry may be slaughtered, or contact with any surfaces that appear to be contaminated with faeces from poultry or other animals. Travellers should also wash their hands often with soap and water. Travellers should follow good food safety and good food hygiene practices.

WHO does not advise special screening at points of entry with regard to this event, nor does it currently recommend any travel or trade restrictions.

As always, a diagnosis of infection with an avian influenza virus should be considered in individuals who develop severe acute respiratory symptoms while travelling or soon after returning from an area where avian influenza is a concern.

WHO encourages countries to continue strengthening influenza surveillance, including surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns, in order to ensure reporting of human infections under the IHR (2005), and continue national health preparedness actions.

WHO
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